Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants

Journal of Biological Chemistry

Volumn 285, Issue 15, 2010, Pages 11106-11113

  Li, Kai ^a   Bethea, Heather N ^a   Liu, Jian ^a  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COUPLING SYSTEMS; GLUCOSAMINES; GLUCURONIC ACIDS; HEPARAN SULFATES; IDURONIC ACID; PATHOPHYSIOLOGICAL; SULFATED POLYSACCHARIDES; WILD-TYPE PROTEINS;

BIOCHEMISTRY; ENZYMES; GLUCOSE; HYDRAULIC STRUCTURES;

ACIDS;

EPIMERASE; GLUCOSAMINE; GLUCURONIC ACID; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARAN SULFATE; IDURONIC ACID; POLYSACCHARIDE; SULFATE; SULFOTRANSFERASE; TRITIUM;

ARTICLE; CARBOHYDRATE ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME ENGINEERING; ENZYME MODIFICATION; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SULFATION; SYNTHESIS; WILD TYPE;

CARBOHYDRATE EPIMERASES; CATALYSIS; CATALYTIC DOMAIN; DISACCHARIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCURONIC ACID; HUMANS; IDURONIC ACID; MODELS, CHEMICAL; MUTAGENESIS; MUTATION; POLYSACCHARIDES; PROTEIN ENGINEERING; SULFOTRANSFERASES; TYROSINE;

EID: 77951245025     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.081059     Document Type: Article

References (35)

1. Kreuger, J., Spillmann, D., Li, J. P., and Lindahl, U. (2006) J. Cell Biol. 174, 323-327
2. Capila, I., and Linhardt, R. J. (2002) Angew. Chem. Int. Ed. Engl. 41, 391-412
3. Bishop, J. R., Schuksz, M., and Esko, J. D. (2007) Nature 446, 1030-1037
4. Liu, J., and Pedersen, L. C. (2007) Appl. Microbiol. Biotechnol. 74, 263-272
5. Liu, J., and Thorp, S. C. (2002) Med. Res. Rev. 22, 1-25
6. Sasisekharan, R., Shriver, Z., Venkataraman, G., and Narayanasami, U. (2002) Nat. Rev. Cancer 2, 521-528
7. Gama, C. I., Tully, S. E., Sotogaku, N., Clark, P. M., Rawat, M., Vaidehi, N., Goddard, W. A., 3rd, Nishi, A., and Hsieh-Wilson, L. C. (2006) Nat. Chem. Biol. 2, 467-473
8. Habuchi, H., Habuchi, O., and Kimata, K. (2004) Glycoconj. J. 21, 47-52
9. Nakato, H., and Kimata, K. (2002) Biochim. Biophys. Acta 1573, 312-318
10. Peterson, S. P., Frick, A., and Liu, J. (2009) Nat. Prod. Rep. 26, 610-627
11. Raman, R., Venkataraman, G., Ernst, S., Sasisekharan, V., and Sasisekharan, R. (2003) Proc. Natl. Acad. Sci. 100, 2357-2362
12. Chen, J., Jones, C. L., and Liu, J. (2007) Chem. Biol. 14, 986-993
13. Jia, J., Maccarana, M., Zhang, X., Bespalov, M., Lindahl, U., and Li, J. P. (2009) J. Biol. Chem. 284, 15942-15950
14. Das, S. K., Mallet, J. M., Esnault, J., Driguez, P. A., Duchaussoy, P., Sizun, P., Herault, J. P., Herbert, J. M., Petitou, M., and Sinaÿ, P. (2001) Chemistry 7, 4821-4834
15. Li, J. P., Gong, F., Hagner-McWhirter, A., Forsberg, E., Abrink, M., Kisilevsky, R., Zhang, X., and Lindahl, U. (2003) J. Biol. Chem. 278, 28363-28366
16. Pinhal, M. A., Smith, B., Olson, S., Aikawa, J., Kimata, K., and Esko, J. D. (2001) Proc. Natl. Acad. Sci. 98, 12984-12989
17. Kakuta, Y., Li, L., Pedersen, L. C., Pedersen, L. G., and Negishi, M. (2003) Biochem. Soc. Trans. 31, 331-334
18. Edavettal, S. C., Lee, K. A., Negishi, M., Linhardt, R. J., Liu, J., and Pedersen, L. C. (2004) J. Biol. Chem. 279, 25789-25797
19. Xu, D., Moon, A. F., Song, D., Pedersen, L. C., and Liu, J. (2008) Nat. Chem. Biol. 4, 200-202
20. Bethea, H. N., Xu, D., Liu, J., and Pedersen, L. C. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 18724-18729
21. Moon, A. F., Edavettal, S. C., Krahn, J. M., Munoz, E. M., Negishi, M., Linhardt, R. J., Liu, J., and Pedersen, L. C. (2004) J. Biol. Chem. 279, 45185-45193
22. Campbell, P., Hannesson, H. H., Sandbäck, D., Rodén, L., Lindahl, U., and Li, J. P. (1994) J. Biol. Chem. 269, 26953-26958
23. Li, J., Hagner-McWhirter, A., Kjellén, L., Palgi, J., Jalkanen, M., and Lindahl, U. (1997) J. Biol. Chem. 272, 28158-28163
24. Muñoz, E., Xu, D., Avci, F., Kemp, M., Liu, J., and Linhardt, R. J. (2006) Biochem. Biophys. Res. Commun. 339, 597-602
25. Lindahl, U., Li, J. P., Kusche-Gullberg, M., Salmivirta, M., Alaranta, S., Veromaa, T., Emeis, J., Roberts, I., Taylor, C., Oreste, P., Zoppetti, G., Naggi, A., Torri, G., and Casu, B. (2005) J. Med. Chem. 48, 349-352
26. Vann, W. F., Schmidt, M. A., Jann, B., and Jann, K. (1981) Eur. J. Biochem. 116, 359-364
27. Xia, G., Chen, J., Tiwari, V., Ju, W., Li, J. P., Malmstrom, A., Shukla, D., and Liu, J. (2002) J. Biol. Chem. 277, 37912-37919
28. Duncan, M. B., Liu, M., Fox, C., and Liu, J. (2006) Biochem. Biophys. Res. Commun. 339, 1232-1237
29. Shively, J. E., and Conrad, H. E. (1976) Biochemistry 15, 3932-3942
30. Chen, J., Duncan, M. B., Carrick, K., Pope, R. M., and Liu, J. (2003) Glycobiology 13, 785-794
31. Chen, J., and Liu, J. (2005) Biochim. Biophys. Acta 1725, 190-200
32. Pacheco, B., Maccarana, M., Goodlett, D. R., Malmström, A., and Malmström, L. (2009) J. Biol. Chem. 284, 1741-1747
33. Rost, B., Yachdav, G., and Liu, J. (2004) Nucleic Acids Res. 32, W321-W326
34. Shaya, D., Tocilj, A., Li, Y., Myette, J., Venkataraman, G., Sasisekharan, R., and Cygler, M. (2006) J. Biol. Chem. 281, 15525-15535
35. Shriver, Z., Hu, Y., Pojasek, K., and Sasisekharan, R. (1998) J. Biol. Chem. 273, 22904-22912