Heparan sulphate N-sulphotransferase activity: Reaction mechanism and substrate recognition

Biochemical Society Transactions

Volumn 31, Issue 2, 2003, Pages 331-334

  Kakuta, Y ^a,b   Li, L ^a   Pedersen, L C ^a,c   Pedersen, L G ^a   Negishi, M ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Acceptor substrate binding; Catalytic mechanism; Glycosaminylglycan; Heparan sulphate N sulphotransferase; Molecular modelling; X ray crystal structure

Indexed keywords

ACYLTRANSFERASE; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; ASPARAGINE; GLUTAMIC ACID; GLUTAMINE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE N DEACETYLASE; HEPARAN SULFATE N SULFOTRANSFERASE; HISTIDINE; PHENYLALANINE; SULFOTRANSFERASE; TRISACCHARIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALPHA HELIX; BINDING SITE; CATALYSIS; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR MODEL; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; SUBSTRATE SPECIFICITY; SULFOTRANSFERASES;

FRAXINUS;

EID: 0242416911     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0310331     Document Type: Conference Paper

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