Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-α

Journal of Biological Chemistry

Volumn 285, Issue 16, 2010, Pages 11974-11982

  Matsushita, Kenichi ^a,b   Morello, Fulvio ^a   Wu, Yaojiong ^a   Zhang, Lunan ^a   Iwanaga, Shiro ^b   Pratt, Richard E ^a   Dzau, Victor J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; ENDOCRINE CELLS; JUXTAGLOMERULAR CELLS; KEY ENZYMES; LIVER X RECEPTORS; MESENCHYMAL STEM CELL; NUCLEAR HORMONE RECEPTOR; PATHOPHYSIOLOGY; RENIN-ANGIOTENSIN SYSTEM; SECRETORY GRANULES; SMOOTH MUSCLE ACTINS; TRANSCRIPTIONAL REGULATOR;

CELL CULTURE; FETAL MONITORING; FLOWCHARTING; GENE EXPRESSION; GENE EXPRESSION REGULATION; LIVER;

STEM CELLS;

ALPHA SMOOTH MUSCLE ACTIN; CYCLIC AMP; LIVER X RECEPTOR ALPHA; RENIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; JUXTAGLOMERULAR CELL; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENIN RELEASE; SECRETORY GRANULE; TRANSCRIPTION REGULATION;

ACTINS; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE; CYCLIC AMP; GENE EXPRESSION; HUMANS; HYDROXYCHOLESTEROLS; JUXTAGLOMERULAR APPARATUS; LIGANDS; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; ORPHAN NUCLEAR RECEPTORS; RECOMBINANT FUSION PROTEINS; RENIN; RENIN-ANGIOTENSIN SYSTEM; RNA, SMALL INTERFERING;

MURINAE;

EID: 77951231534     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.099671     Document Type: Article

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