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Volumn 34, Issue 4, 2006, Pages 117-128

Antidiabetic activity of benzyl tetra isoquinoline alkaloid berberine in streptozotocin-nicotinamide induced type 2 diabetic rats

Author keywords

Antidiabetic activity; Antioxidants; Berberine; Carbohydrate metabolism; Streptozotocin nicotinamide induced diabetes

Indexed keywords

BENZYL TETRA ISOQUINOLINE; BERBERINE DERIVATIVE; CARBOHYDRATE; GLYCOSYLATED HEMOGLOBIN; QUINOLONE DERIVATIVE; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

EID: 33748675277     PISSN: 03510042     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (54)

References (69)
  • 1
    • 0034652383 scopus 로고    scopus 로고
    • Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydrocarpin a multidrug pump inhibitor
    • Stermitz FR, Lorenz P, Tawara JN, Zenewica LA, Lewis K. Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5′-methoxyhydrocarpin a multidrug pump inhibitor. Proc Natl Acad Sci USA 2001;97:1433-1437.
    • (2001) Proc Natl Acad Sci USA , vol.97 , pp. 1433-1437
    • Stermitz, F.R.1    Lorenz, P.2    Tawara, J.N.3    Zenewica, L.A.4    Lewis, K.5
  • 2
    • 0014569720 scopus 로고
    • Berberine sulfate: Antimicrobial activity, bioassay and mode of action
    • Amin AH, Subbaiah TV, Abbasi KM. Berberine sulfate: antimicrobial activity, bioassay and mode of action. Can J Microbiol 1969;15:1067-1076.
    • (1969) Can J Microbiol , vol.15 , pp. 1067-1076
    • Amin, A.H.1    Subbaiah, T.V.2    Abbasi, K.M.3
  • 3
    • 84907134586 scopus 로고
    • Antimycotic activity of berberine sulphate: An alkaloid from an Indian medicinal herb
    • Mahajan, VM, Sharma A, Rattan A. Antimycotic activity of berberine sulphate: an alkaloid from an Indian medicinal herb. Sabouraudia 1982;20:79-81.
    • (1982) Sabouraudia , vol.20 , pp. 79-81
    • Mahajan, V.M.1    Sharma, A.2    Rattan, A.3
  • 4
    • 0014220647 scopus 로고
    • Effect of berberine sulfate on Entamoeba histolytica
    • Subbaiah TV, Amin AH. Effect of berberine sulfate on Entamoeba histolytica. Nature 1967;215:527-528.
    • (1967) Nature , vol.215 , pp. 527-528
    • Subbaiah, T.V.1    Amin, A.H.2
  • 5
    • 0028610130 scopus 로고
    • Kinetic analysis of interaction of human immunodeficiency virus reverse transcriptase with alkaloids
    • Gudima SO, Memelova LV, Borodulin VB. Kinetic analysis of interaction of human immunodeficiency virus reverse transcriptase with alkaloids. Mol Biol (Mosk) 1994;28:1308-1314.
    • (1994) Mol Biol (Mosk) , vol.28 , pp. 1308-1314
    • Gudima, S.O.1    Memelova, L.V.2    Borodulin, V.B.3
  • 6
    • 33748657781 scopus 로고
    • Anthelmintic activity of berberine hydrochloride in trachoma
    • Singhal KC. Anthelmintic activity of berberine hydrochloride in trachoma. Indian J Ophthalmol 1982;30:69-75.
    • (1982) Indian J Ophthalmol , vol.30 , pp. 69-75
    • Singhal, K.C.1
  • 9
    • 0028867729 scopus 로고
    • Berberine inhibition of electrogenic ion transport in rat colon
    • Taylor CT, Baird AW. Berberine inhibition of electrogenic ion transport in rat colon. Br J Pharmacol 1995;116:2667-2672.
    • (1995) Br J Pharmacol , vol.116 , pp. 2667-2672
    • Taylor, C.T.1    Baird, A.W.2
  • 10
    • 0018727519 scopus 로고
    • Possible mechanism of antidiarrhoeal effect of berberine
    • Akhter MH, Sabir M, Bhide NK. Possible mechanism of antidiarrhoeal effect of berberine. Indian J Med Res 1979;70:233-241.
    • (1979) Indian J Med Res , vol.70 , pp. 233-241
    • Akhter, M.H.1    Sabir, M.2    Bhide, N.K.3
  • 11
    • 0024372136 scopus 로고
    • Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction
    • Xu Z, Cao HY, Li Q. Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction. Chung Kuo Yao Li Hsueh Pao 1989;10:320-324.
    • (1989) Chung Kuo Yao Li Hsueh Pao , vol.10 , pp. 320-324
    • Xu, Z.1    Cao, H.Y.2    Li, Q.3
  • 12
    • 0029563102 scopus 로고
    • Inhibition of in vitro lymphocyte transformation by the isoquinoline alkaloid berberine
    • Ckless K, Schlottfeldt J, Pasqual M. Inhibition of in vitro lymphocyte transformation by the isoquinoline alkaloid berberine. J Pharm Pharmacol 1995;47:1029-1031.
    • (1995) J Pharm Pharmacol , vol.47 , pp. 1029-1031
    • Ckless, K.1    Schlottfeldt, J.2    Pasqual, M.3
  • 13
    • 0029174128 scopus 로고
    • Effects of berberine in platelet aggregation and plasma levels of TXb2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion
    • Wu JF, Liu TP. Effects of berberine in platelet aggregation and plasma levels of TXb2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion. Yao Hsueh Hsueh Pao 1995;30:98-102.
    • (1995) Yao Hsueh Hsueh Pao , vol.30 , pp. 98-102
    • Wu, J.F.1    Liu, T.P.2
  • 14
    • 0017606693 scopus 로고
    • The effects of berberine on bilirubin excretion in the rat
    • Chan MY The effects of berberine on bilirubin excretion in the rat. Gomp Med East West 1977;5:161-168.
    • (1977) Gomp Med East West , vol.5 , pp. 161-168
    • Chan, M.Y.1
  • 15
    • 0025614252 scopus 로고
    • The role and mechanism of berberine on coronary arteries
    • Huang W The role and mechanism of berberine on coronary arteries. Chung Hua Hsin Hsueh Kuan Ping Tsa Chih 1990;18:231-234.
    • (1990) Chung Hua Hsin Hsueh Kuan Ping Tsa Chih , vol.18 , pp. 231-234
    • Huang, W.1
  • 16
    • 0344461936 scopus 로고
    • Inhibitory effect of berberine on potassium channels in guinea pig ventricular mycocytes
    • Hua Z, Wang XL. Inhibitory effect of berberine on potassium channels in guinea pig ventricular mycocytes. Acta Pharm Sinica 1994;29:576-580.
    • (1994) Acta Pharm Sinica , vol.29 , pp. 576-580
    • Hua, Z.1    Wang, X.L.2
  • 17
    • 0041492388 scopus 로고    scopus 로고
    • Effect of Huang Lian Su on nerve conduction velocity and hormone level to diabetic neuropathy in rats
    • Hua WG, Song JM, Liao H. Effect of Huang Lian Su on nerve conduction velocity and hormone level to diabetic neuropathy in rats. Labeled Immunoassays & Clin Med 2001;8:212-214.
    • (2001) Labeled Immunoassays & Clin Med , vol.8 , pp. 212-214
    • Hua, W.G.1    Song, J.M.2    Liao, H.3
  • 18
    • 0041379639 scopus 로고    scopus 로고
    • The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption
    • Guo-Yu Pan, Zhi-Jiang Huang, Guang-Ji Wang. The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption. Planta Med 2003;69:632-636.
    • (2003) Planta Med , vol.69 , pp. 632-636
    • Pan, G.-Y.1    Huang, Z.-J.2    Wang, G.-J.3
  • 19
    • 1842708890 scopus 로고    scopus 로고
    • Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion
    • Leng SH, Lu E Xu LJ. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacol Sinica 2004;25:496-502.
    • (2004) Acta Pharmacol Sinica , vol.25 , pp. 496-502
    • Leng, S.H.1    Lu, E.2    Xu, L.J.3
  • 22
    • 0024508097 scopus 로고
    • Compensatory growth of pancreatic β cells in adult rats after short-term glucose infusion
    • Bonner-Weir S, Dery D, John LL, Gordon CW Compensatory growth of pancreatic β cells in adult rats after short-term glucose infusion. Diabetes 1989;38:49-53.
    • (1989) Diabetes , vol.38 , pp. 49-53
    • Bonner-Weir, S.1    Dery, D.2    John, L.L.3    Gordon, C.W.4
  • 23
    • 0031939587 scopus 로고    scopus 로고
    • Development of a new model of type 2 diabetes in adult rats administered with streptozotocin and nicotinamide
    • Pellegrino M, Broca C, Gross R, Rove M, Manteghetti M, Hillaire-Buys D. Development of a new model of type 2 diabetes in adult rats administered with streptozotocin and nicotinamide. Diabetes 1998;47:224-229.
    • (1998) Diabetes , vol.47 , pp. 224-229
    • Pellegrino, M.1    Broca, C.2    Gross, R.3    Rove, M.4    Manteghetti, M.5    Hillaire-Buys, D.6
  • 24
    • 78651047985 scopus 로고
    • The determination of glycogen in liver and muscle by use of anthrone reagent
    • Nicholas V. The determination of glycogen in liver and muscle by use of anthrone reagent. Indian J Biol Chem 1956;220:583-587.
    • (1956) Indian J Biol Chem , vol.220 , pp. 583-587
    • Nicholas, V.1
  • 25
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 26
    • 7144228388 scopus 로고
    • Determination of hexokinase in tissues
    • Brandstrup N, Kirk JE, Bruni C. Determination of hexokinase in tissues. J Gerontol 1957;12:166-171.
    • (1957) J Gerontol , vol.12 , pp. 166-171
    • Brandstrup, N.1    Kirk, J.E.2    Bruni, C.3
  • 27
    • 0001422064 scopus 로고
    • Glucose 6 phosphate dehydrogenase
    • Deerfield Beach, FL: Verlag Chemie
    • rd edition. Deerfield Beach, FL: Verlag Chemie, 1983; p. 190.
    • (1983) rd Edition , vol.3 , pp. 190
    • Deutsch, J.1
  • 28
    • 0000191753 scopus 로고
    • Lactate dehydrogenase
    • Deerfield Beach, FL: Verlag Chemie
    • rd edition. Deerfield Beach, FL: Verlag Chemie, 1983; p. 118.
    • (1983) rd Edition , vol.3 , pp. 118
    • Vassault, A.1
  • 30
    • 0001810816 scopus 로고
    • Alanine amino transferase
    • Deerfield Beach, FL: Verlag Chemie
    • rd edition. Deerfield Beach, FL: Verlag Chemie, 1983; p. 190.
    • (1983) rd Edition , vol.3 , pp. 190
    • Horder, M.1    Rej, R.2
  • 32
    • 0000024076 scopus 로고
    • Catalase
    • Deerfield Beach, FL: Verlag Chemie
    • rd edition. Deerfield Beach, FL: Verlag Chemie, 1983; p. 273.
    • (1983) rd Edition , vol.3 , pp. 273
    • Aebi, E.H.1
  • 33
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha KA. Colorimetric assay of catalase. Anal Biochem 1972;47:389-394.
    • (1972) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, K.A.1
  • 34
    • 0000735565 scopus 로고
    • Peroxidase
    • Deerfield Beach, FL: Verlag Chemie
    • rd edition. Deerfield Beach, FL: Verlag Chemie, 1983; p. 286.
    • (1983) rd Edition , vol.3 , pp. 286
    • Putter, J.1    Becker, R.2
  • 35
    • 0021681627 scopus 로고
    • A modified spectrophotometric assay of superoxide dismutase
    • Kakkar P, Dos B, Viswanathan RN. A modified spectrophotometric assay of superoxide dismutase. Ind J Biochem Biophys 1984;21:130-132.
    • (1984) Ind J Biochem Biophys , vol.21 , pp. 130-132
    • Kakkar, P.1    Dos, B.2    Viswanathan, R.N.3
  • 36
    • 50549170204 scopus 로고
    • An improved colorimetric assay of ceruloplasmin
    • Ravin HA. An improved colorimetric assay of ceruloplasmin. J Labor Clin Med 1961;589:161-168.
    • (1961) J Labor Clin Med , vol.589 , pp. 161-168
    • Ravin, H.A.1
  • 37
    • 0021288822 scopus 로고
    • Vitamin E analysis methods for animal tissues
    • Desai LD. Vitamin E analysis methods for animal tissues. Methods Enzymol 1984;105:138-142.
    • (1984) Methods Enzymol , vol.105 , pp. 138-142
    • Desai, L.D.1
  • 38
    • 0018369625 scopus 로고
    • Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids
    • McCormick DB, Wright CD, eds. New York: Academic Press
    • Omaye ST, Turnball JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. In: McCormick DB, Wright CD, eds. Methods in enzymology, Vol. 62. New York: Academic Press, 1979; p. 1-11.
    • (1979) Methods in Enzymology , vol.62 , pp. 1-11
    • Omaye, S.T.1    Turnball, J.D.2    Sauberlich, H.E.3
  • 42
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications
    • Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications. Diabetes 1999;48:1-9.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 43
    • 0029996118 scopus 로고    scopus 로고
    • Effect of experimental diabetes and insulin on smooth muscle functions
    • Ozturk Y, Altan VM, Yildizoglu A. Effect of experimental diabetes and insulin on smooth muscle functions. Pharmacol Rev 1996;48:69-112.
    • (1996) Pharmacol Rev , vol.48 , pp. 69-112
    • Ozturk, Y.1    Altan, V.M.2    Yildizoglu, A.3
  • 44
    • 0025073589 scopus 로고
    • Traditional plant treatments for diabetes: Studies in normal and streptozotocin diabetic mice
    • Swanston-Flat SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes: studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-464.
    • (1990) Diabetologia , vol.33 , pp. 462-464
    • Swanston-Flat, S.K.1    Day, C.2    Bailey, C.J.3    Flatt, P.R.4
  • 45
    • 0017107522 scopus 로고
    • Juvenile diabetes mellitus and serum lipids and lipoprotein levels
    • Chase PH, Glasgow AM. Juvenile diabetes mellitus and serum lipids and lipoprotein levels. Am J Dis Child 1976;130:1113.
    • (1976) Am J Dis Child , vol.130 , pp. 1113
    • Chase, P.H.1    Glasgow, A.M.2
  • 46
    • 0015546146 scopus 로고
    • Plasma transport kinetics in diabetes mellitus
    • Nikkila EA, Kekki M. Plasma transport kinetics in diabetes mellitus. Metabolism 1973;22:1-22.
    • (1973) Metabolism , vol.22 , pp. 1-22
    • Nikkila, E.A.1    Kekki, M.2
  • 47
    • 13544254451 scopus 로고    scopus 로고
    • Antidiabetic activity of alcoholic stem extract of C. fenestratum in streptozotocin nicotinamide induced type 2 diabetic rats
    • Shirwaikar A, Rajendran K, Punitha ISR. Antidiabetic activity of alcoholic stem extract of C. fenestratum in streptozotocin nicotinamide induced type 2 diabetic rats. J Ethnopharmacol 2005;97:369-374.
    • (2005) J Ethnopharmacol , vol.97 , pp. 369-374
    • Shirwaikar, A.1    Rajendran, K.2    Punitha, I.S.R.3
  • 48
    • 0002447814 scopus 로고    scopus 로고
    • Regulation of metabolic pathways in liver and kidney during experimental diabetes: Effects of antidiabetic compounds
    • Baquer NZ, Gupta D, Raju J. Regulation of metabolic pathways in liver and kidney during experimental diabetes: effects of antidiabetic compounds. Ind J Clin Biochem 1998;13:63-80.
    • (1998) Ind J Clin Biochem , vol.13 , pp. 63-80
    • Baquer, N.Z.1    Gupta, D.2    Raju, J.3
  • 49
    • 0042243627 scopus 로고    scopus 로고
    • Antihyperglycaemic effect of aqueous and ethanolic extract of Gongronema latifolium levels of glucose and glycogen metabolism in liver of normal and STZ induced diabetic rats
    • Ugochukwu NH, Babady NE. Antihyperglycaemic effect of aqueous and ethanolic extract of Gongronema latifolium levels of glucose and glycogen metabolism in liver of normal and STZ induced diabetic rats. Life Sci 2003;73:1924-1938.
    • (2003) Life Sci , vol.73 , pp. 1924-1938
    • Ugochukwu, N.H.1    Babady, N.E.2
  • 50
  • 51
    • 1942453616 scopus 로고    scopus 로고
    • Glycolysis and gluconeogenesis
    • Berg JM, Tymoczko JL, Stryer L, eds. New York: WH. Freeman and Company
    • Berg JM, Tymoczko JL, Stryer L. Glycolysis and gluconeogenesis. In: Berg JM, Tymoczko JL, Stryer L, eds. Biochemistry. New York: WH. Freeman and Company, 2001; p. 425-464.
    • (2001) Biochemistry , pp. 425-464
    • Berg, J.M.1    Tymoczko, J.L.2    Stryer, L.3
  • 52
    • 0034908609 scopus 로고    scopus 로고
    • Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats
    • Ghosh S, Suryawanshi SA. Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats. Ind J Exp Biol 2001;39:748-759.
    • (2001) Ind J Exp Biol , vol.39 , pp. 748-759
    • Ghosh, S.1    Suryawanshi, S.A.2
  • 53
    • 0014868755 scopus 로고
    • Plasma amino acid levels in diabetic ketoacidosis
    • Felig P, Marliss E, Ohman J, Cahill JF. Plasma amino acid levels in diabetic ketoacidosis. Diabetes 1970;19:727-730.
    • (1970) Diabetes , vol.19 , pp. 727-730
    • Felig, P.1    Marliss, E.2    Ohman, J.3    Cahill, J.F.4
  • 54
    • 0034457043 scopus 로고    scopus 로고
    • Impaired insulin stimulated expression of the glycogen synthase gene in skeletal muscle of type 2 diabetic parents is acquired rather than inherited
    • Huang X, Vaag A, Hanson M, Weng J, Goop L. Impaired insulin stimulated expression of the glycogen synthase gene in skeletal muscle of type 2 diabetic parents is acquired rather than inherited. J Clin Endocrinol Metab 2000;85:1584-1590.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1584-1590
    • Huang, X.1    Vaag, A.2    Hanson, M.3    Weng, J.4    Goop, L.5
  • 55
    • 0016834286 scopus 로고
    • Glycogen synthesis in perfused liver of STZ diabetic rats
    • Whitton PP, Hems DA. Glycogen synthesis in perfused liver of STZ diabetic rats. Biochem J 1975;150:153.
    • (1975) Biochem J , vol.150 , pp. 153
    • Whitton, P.P.1    Hems, D.A.2
  • 57
    • 0015056379 scopus 로고
    • An enzyme based theory of obligate anaerobiosis, the physiological functions of superoxide dismutase
    • McCord JM, Keele BB, Fridovich I. An enzyme based theory of obligate anaerobiosis, the physiological functions of superoxide dismutase. Proc Natl Acad Sci USA 1976;68:1024-1027.
    • (1976) Proc Natl Acad Sci USA , vol.68 , pp. 1024-1027
    • McCord, J.M.1    Keele, B.B.2    Fridovich, I.3
  • 59
    • 0018835727 scopus 로고
    • Glutathione peroxide effect of superoxide, hydroxyl and bromine free radicals on enzyme activity
    • Searle AJ, Wilson R. Glutathione peroxide effect of superoxide, hydroxyl and bromine free radicals on enzyme activity. Int J Radiat Biol 1980;37:213-217.
    • (1980) Int J Radiat Biol , vol.37 , pp. 213-217
    • Searle, A.J.1    Wilson, R.2
  • 60
    • 0021695489 scopus 로고
    • New aspects of glutathione biochemistry and transport selective alterations of glutathione metabolism
    • Meister A. New aspects of glutathione biochemistry and transport selective alterations of glutathione metabolism. Nutr Rev 1984;42:397-410.
    • (1984) Nutr Rev , vol.42 , pp. 397-410
    • Meister, A.1
  • 61
    • 0022511392 scopus 로고
    • Role of thiols in protection against biological reactive intermediates
    • Nicotera P, Orrenius S. Role of thiols in protection against biological reactive intermediates. Adv Exp Med Biol 1986;97:41-49.
    • (1986) Adv Exp Med Biol , vol.97 , pp. 41-49
    • Nicotera, P.1    Orrenius, S.2
  • 62
    • 0027215582 scopus 로고
    • Effect of oral methionine on tissue lipid peroxidation and antioxidants in alloxan induced diabetic rats
    • Anuradha CV, Selvam R. Effect of oral methionine on tissue lipid peroxidation and antioxidants in alloxan induced diabetic rats. J Nutr Biochem 1993;4:212-217.
    • (1993) J Nutr Biochem , vol.4 , pp. 212-217
    • Anuradha, C.V.1    Selvam, R.2
  • 63
    • 0020427486 scopus 로고
    • Biology of disease-free radicals and tissue injury
    • Bruce A, Freeman D, James C. Biology of disease-free radicals and tissue injury. Lab Invest 1982;47:412-426.
    • (1982) Lab Invest , vol.47 , pp. 412-426
    • Bruce, A.1    Freeman, D.2    James, C.3
  • 64
    • 0020035640 scopus 로고
    • The effect of diabetes on the activities of the peroxide metabolic enzymes
    • Matcovis B, Varga SI, Szaluo Witsas H. The effect of diabetes on the activities of the peroxide metabolic enzymes. Horm Metab Res 1982;14:77-79.
    • (1982) Horm Metab Res , vol.14 , pp. 77-79
    • Matcovis, B.1    Varga, S.I.2    Szaluo Witsas, H.3
  • 65
    • 0034437435 scopus 로고    scopus 로고
    • Lipid peroxidation and scavenging enzyme activity in streptozotocin induced diabetes
    • Kinalski M, Sledziewski A, Telejko B, Zarzycki W, Kinalska T. Lipid peroxidation and scavenging enzyme activity in streptozotocin induced diabetes. Acta Diabetol 2000;37:179-183.
    • (2000) Acta Diabetol , vol.37 , pp. 179-183
    • Kinalski, M.1    Sledziewski, A.2    Telejko, B.3    Zarzycki, W.4    Kinalska, T.5
  • 67
    • 0001218860 scopus 로고
    • Ascorbate is an outstanding antioxidant in human blood plasma
    • Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 1986;86:6377-6381.
    • (1986) Proc Natl Acad Sci USA , vol.86 , pp. 6377-6381
    • Frei, B.1    England, L.2    Ames, B.N.3
  • 68
    • 0023933505 scopus 로고
    • The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin e
    • Inefers H, Sies H. The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. Eur J Biochem 1988;174:353-357.
    • (1988) Eur J Biochem , vol.174 , pp. 353-357
    • Inefers, H.1    Sies, H.2
  • 69
    • 0031774992 scopus 로고    scopus 로고
    • Effect of curcumin on the advanced glycation and cross linking of collagen in diabetic rats
    • Sajithlal GB, Chitra P, Chandrakasan G. Effect of curcumin on the advanced glycation and cross linking of collagen in diabetic rats. Biochem Pharmacol 1998;56:1607-1614.
    • (1998) Biochem Pharmacol , vol.56 , pp. 1607-1614
    • Sajithlal, G.B.1    Chitra, P.2    Chandrakasan, G.3


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