Dimerization of adiponectin receptor 1 is inhibited by adiponectin

Journal of Cell Science

Volumn 123, Issue 8, 2010, Pages 1320-1328

  Kosel, David ^a   Heiker, John T ^a   Juhl, Cathleen ^a   Wottawah, Cornelia M ^a   Blüher, Matthias ^a   Mörl, Karin ^a   Beck Sickinger, Annette G ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Adiponectin; Adiponectin receptor; Bimolecular fluorescence complementation; Receptor dimerization

Indexed keywords

ADIPONECTIN RECEPTOR 1;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF;

ADIPONECTIN; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE; CELL SURVIVAL; FLOW CYTOMETRY; FLUORESCENCE; HUMANS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, ADIPONECTIN; SUBCELLULAR FRACTIONS;

EID: 77951201291     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.057919     Document Type: Article

References (51)

1. Berg, A. H., Combs, T. P. and Scherer, P. E. (2002). ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab. 13, 84-89.
2. Bergstrom, J. (1975). Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand. J. Clin. Lab. Invest. 35, 609-616.
3. Berthouze, M., Rivail, L., Lucas, A., Ayoub, M. A., Russo, O., Sicsic, S., Fischmeister, R., Berque-Bestel, I., Jockers, R. and Lezoualc'h, F. (2007). Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization. Biochem. Biophys. Res. Commun. 356, 642-647.
4. Cabrele, C., Langer, M., Bader, R., Wieland, H. A., Doods, H. N., Zerbe, O. and Beck-Sickinger, A. G. (2000). The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J. Biol. Chem. 275, 36043-36048.
5. Chen, C. D., Oh, S. Y., Hinman, J. D. and Abraham, C. R. (2006). Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation. J. Neurochem. 97, 30-43.
6. Deckert, C. M., Heiker, J. T. and Beck-Sickinger, A. G. (2006). Localization of novel adiponectin receptor constructs. J. Recept. Signal Transduct. 26, 647-657.
7. Dinger, M. C., Bader, J. E., Kobor, A. D., Kretzschmar, A. K. and Beck-Sickinger, A. G. (2003). Homodimerization of neuropeptide y receptors investigated by fluorescence resonance energy transfer in living cells. J. Biol. Chem. 278, 10562-10571.
8. Fasshauer, M., Paschke, R. and Stumvoll, M. (2004). Adiponectin, obesity, and cardiovascular disease. Biochimie 86, 779-784.
9. Grant, M., Collier, B. and Kumar, U. (2004). Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking. J. Biol. Chem. 279, 36179-36183.
10. Guo, Y., Rebecchi, M. and Scarlata, S. (2005). Phospholipase Cbeta2 binds to and inhibits phospholipase Cdelta1. J. Biol. Chem. 280, 1438-1447.
11. Heiker, J. T., Wottawah, C. M., Juhl, C., Kosel, D., Morl, K. and Beck-Sickinger, A. G. (2009). Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling. Cell Signal. 21, 936-942.
12. Heroux, M., Hogue, M., Lemieux, S. and Bouvier, M. (2007). Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. J. Biol. Chem. 282, 31610-31620.
13. Herrick-Davis, K., Weaver, B. A., Grinde, E. and Mazurkiewicz, J. E. (2006). Serotonin 5-HT2C receptor homodimer biogenesis in the endoplasmic reticulum: real-time visualization with confocal fluorescence resonance energy transfer. J. Biol. Chem. 281, 27109-27116.
14. Horschitz, S., Lau, T. and Schloss, P. (2008). Glycine residues G338 and G342 are important determinants for serotonin transporter dimerisation and cell surface expression. Neurochem. Int. 52, 770-775.
15. Hu, C.-D., Chinenov, Y. and Kerppola, T. K. (2002). Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell 9, 789-798.
16. Johnson, R. M., Hecht, K. and Deber, C. M. (2007). Aromatic and cation-pi interactions enhance helix-helix association in a membrane environment. Biochemistry 46, 9208-9214.
17. Kadowaki, T., Yamauchi, T., Kubota, N., Hara, K., Ueki, K. and Tobe, K. (2006). Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116, 1784-1792.
18. Kerppola, T. K. (2006). Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells. Nat. Protoc. 1, 1278-1286.
19. Kienlen-Campard, P., Tasiaux, B., Van Hees, J., Li, M., Huysseune, S., Sato, T., Fei, J. Z., Aimoto, S., Courtoy, P. J., Smith, S. O. et al. (2008). Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs. J. Biol. Chem. 283, 7733-7744.
20. Latif, R., Graves, P. and Davies, T. F. (2002). Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor. J. Biol. Chem. 277, 45059-45067.
21. Lemmon, M. A., Flanagan, J. M., Treutlein, H. R., Zhang, J. and Engelman, D. M. (1992). Sequence specificity in the dimerization of transmembrane alpha-helices. Biochemistry 31, 12719-12725.
22. Li, N., Cui, Z., Fang, F., Lee, J. Y. and Ballatori, N. (2007). Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter. Biochem. J. 407, 363-372.
23. Lopez-Gimenez, J. F., Canals, M., Pediani, J. D. and Milligan, G. (2007). The {alpha}1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function. Mol. Pharmacol. 71, 1015-1029.
24. Mandrika, I., Petrovska, R. and Wikberg, J. (2005). Melanocortin receptors form constitutive homo- and heterodimers. Biochem. Biophys. Res. Commun. 326, 349-354.
25. Mao, X., Kikani, C. K., Riojas, R. A., Langlais, P., Wang, L., Ramos, F. J., Fang, Q., Christ-Roberts, C. Y., Hong, J. Y., Kim, R. Y. et al. (2006). APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat. Cell Biol. 8, 516-523.
26. Margeta-Mitrovic, M., Jan, Y. N. and Jan, L. Y. (2000). A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron 27, 97-106.
27. McGaughey, G. B., Gagne, M. and Rappe, A. K. (1998). pi-Stacking interactions. Alive and well in proteins. J. Biol. Chem. 273, 15458-15463.
28. Milligan, G. (2008). A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization. Br. J. Pharmacol. 153, Suppl. 1, S216-S229.
29. Morell, M., Espargaro, A., Aviles, F. X. and Ventura, S. (2007). Detection of transient protein-protein interactions by bimolecular fluorescence complementation: the Abl-SH3 case. Proteomics 7, 1023-1036.
30. Nagai, T., Ibata, K., Park, E. S., Kubota, M., Mikoshiba, K. and Miyawaki, A. (2002). A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat. Biotechnol. 20, 87-90.
31. Nakashima, K., Narazaki, M. and Taga, T. (1997). Leptin receptor (OB-R) oligomerizes with itself but not with its closely related cytokine signal transducer gp130. FEBS Lett. 403, 79-82. (Pubitemid 27079813)
32. Oberbach, A., Bossenz, Y., Lehmann, S., Niebauer, J., Adams, V., Paschke, R., Schon, M. R., Bluher, M. and Punkt, K. (2006). Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes. Diabetes Care 29, 895-900.
33. Overton, M. C., Chinault, S. L. and Blumer, K. J. (2003). Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein -coupled receptor. J. Biol. Chem. 279, 49369-49377.
34. Rath, A., Johnson, R. M. and Deber, C. M. (2007). Peptides as transmembrane segments: decrypting the determinants for helix-helix interactions in membrane proteins. Biopolymers 88, 217-232.
35. Salahpour, A., Angers, S., Mercier, J. F., Lagace, M., Marullo, S. and Bouvier, M. (2004). Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J. Biol. Chem. 279, 33390-33397.
36. Schmidt, C., Peng, B., Li, Z., Sclabas, G. M., Fujioka, S., Niu, J., Schmidt-Supprian, M., Evans, D. B., Abbruzzese, J. L. and Chiao, P. J. (2003). Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Mol. Cell 12, 1287-1300.
37. Senes, A., Engel, D. E. and DeGrado, W. F. (2004). Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr. Opin. Struct. Biol. 14, 465-479.
38. Szczesna-Skorupa, E. and Kemper, B. (2006). BAP31 is involved in the retention of cytochrome P450 2C2 in the endoplasmic reticulum. J. Biol. Chem. 281, 4142-4148.
39. Terrillon, S. and Bouvier, M. (2004). Roles of G-protein-coupled receptor dimerization. EMBO Rep. 5, 30-34.
40. Tilg, H. and Moschen, A. R. (2006). Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat. Rev. Immunol. 6, 772-783.
41. Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K. et al. (2004). Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J. Biol. Chem. 279, 30817-30822.
42. Ward, C. W., Lawrence, M. C., Streltsov, V. A., Adams, T. E. and McKern, N. M. (2007). The insulin and EGF receptor structures: new insights into ligand-induced receptor activation. Trends Biochem. Sci. 32, 129-137.
43. White, D. W., Kuropatwinski, K. K., Devos, R., Baumann, H. and Tartaglia, L. A. (1997). Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization. J. Biol. Chem. 272, 4065-4071.
44. Wolf, A., Keil, R., Gotzl, O., Mun, A., Schwarze, K., Lederer, M., Huttelmaier, S. and Hatzfeld, M. (2006). The armadillo protein p0071 regulates Rho signalling during cytokinesis. Nat. Cell Biol. 8, 1432-1440.
45. Xu, Y., Wang, N., Ling, F., Li, P. and Gao, Y. (2009). Receptor for activated C-kinase 1, a novel binding partner of adiponectin receptor 1. Biochem. Biophys. Res. Commun. 378, 95-98.
46. Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K. et al. (2002). Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8, 1288-1295.
47. Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M. et al. (2003). Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423, 762-769.
48. Yamauchi, T., Nio, Y., Maki, T., Kobayashi, M., Takazawa, T., Iwabu, M., Okada-Iwabu, M., Kawamoto, S., Kubota, N., Kubota, T. et al. (2007). Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat. Med. 13, 332-339.
49. Yoon, M. J., Lee, G. Y., Chung, J. J., Ahn, Y. H., Hong, S. H. and Kim, J. B. (2006). Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 55, 2562-2570.
50. Zanna, P. T., Sanchez-Laorden, B. L., Perez-Oliva, A. B., Turpin, M. C., Herraiz, C., Jimenez-Cervantes, C. and Garcia-Borron, J. C. (2008). Mechanism of dimerization of the human melanocortin 1 receptor. Biochem. Biophys. Res. Commun. 368, 211-216.
51. Zawarynski, P., Tallerico, T., Seeman, P., Lee, S. P., O'Dowd, B. F. and George, S. R. (1998). Dopamine D2 receptor dimers in human and rat brain. FEBS Lett. 441, 383-386.