Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes

Diabetes Care

Volumn 29, Issue 4, 2006, Pages 895-900

  Oberbach, Andreas ^a,b   Bossenz, Yvonne ^b   Lehmann, Stefanie ^b   Niebauer, Josef ^c   Adams, Volker ^a   Paschke, Ralf ^a   Schön, Michael R ^a   Blüher, Matthias ^a,b   Punkt, Karla ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^c PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C; OXIDOREDUCTASE;

ADULT; AEROBIC CAPACITY; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPHOTOMETRY; ENZYME ACTIVITY; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INFUSION; GLYCOLYSIS; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; MALE; MUSCLE CELL; NERVE FIBER; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION; SKELETAL MUSCLE; SKIN BIOPSY; STEADY STATE; VASTUS LATERALIS MUSCLE;

EID: 33746334169     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/diacare.29.04.06.dc05-1854     Document Type: Article

References (19)

1. DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP: The effect of insulin on the disposal of intravenous glucose: results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30:1000-1007, 1981
2. Kelley D, Mandarino L: Fuel selection in human skeletal muscle in insulin resistance: a re-examination. Diabetes 49:677-683, 2000
3. Lillioja S, Young AA, Culter CL, Ivy JL, Abbott WG, Zawadzki JK, Yki-Jarvinen H, Christin L, Secomb TW, Bogardus C: Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. J Clin Invest 80:415-424, 1987
4. Gaster M, Staehr P, Beck-Nielsen H, Schroder HD, Handberg A: GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients. Diabetes 50:1324-1329, 2001
5. Lithell H, Lindgarde F, Hellsing K, Lundqvist G, Nygaard E, Vessby B, Saltin B: Body weight, skeletal muscle morphology, and enzyme activities in relation to fasting serum insulin concentration and glucose tolerance in 48-year-old men. Diabetes 30:19-25, 1981
6. Simoneau JA, Kelley DE: Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in type 2 diabetes. J Appl Physiol 83:166-171, 1997
7. He J, Watkins S, Kelley DE: Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity. Diabetes 50:817-823, 2001
8. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 23 (Suppl. 1):S4-S19, 2000
9. Blüher M, Unger R, Rassoul F, Richter V, Paschke R: Relation between glycaemic control, hyperinsulinaemia and plasma concentrations of soluble adhesion molecules in patients with impaired glucose tolerance or type II diabetes. Diabetologia 45:210-216, 2002
10. DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223, 1979
11. Punkt K, Mehlhorn H, and Hilbig H: Region- and age-dependent variations of muscle fibre properties. Acta Histochem 100:37-58, 1998
12. Punkt K: Fibre types in skeletal muscles. Adv Anat Embryol Cell Biol 162:1-112, 2002
13. Bruce CR, Anderson MJ, Carey AL, Newman DG, Bonen A, Kriketos AD, Cooney GJ, Hawley JA: Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. J Clin Endocrinol Metab 88:5444-5451, 2003
14. Simoneau JA, Colberg SR, Thaete FL, Kelley DE: Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB J 9:273-278, 1995
15. Simoneau JA, Bouchard C: Human variation in skeletal muscle fiber-type proportion and enzyme activities. Am J Physiol 257:E567-E572, 1989
16. Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE: Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579-1585, 1997
17. Hickey MS, Carey JO, Azevedo JL, Houmard JA, Pories WJ, Israel RG, Dohm GL: Skeletal muscle fiber composition is related to adiposity and in vitro glucose transport rate in humans. Am J Physiol 268:E453-E457, 1995
18. Simoneau JA, Veerkamp JH, Turcotte LP, Kelley DE: Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J 13:2051-2060, 1999
19. Van der Laarse WJ, Diegenbach PC, Hemminga MA: Calcium-stimulated myofibrillar ATPase activity correlates with shortening velocity of muscle fibres in Xenopis laevis. Histochem J 18:487-496, 1986