Total synthesis of "Aliskiren": The first renin inhibitor in clinical practice for hypertension

Organic Letters

Volumn 12, Issue 8, 2010, Pages 1816-1819

  Hanessian, Stephen ^a   Guesné, Sébastien ^a   Chénard, Etienne ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALISKIREN; AMIDE; ANTIHYPERTENSIVE AGENT; FUMARIC ACID DERIVATIVE; PROTEINASE INHIBITOR; RENIN;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; HYPERTENSION; STEREOISOMERISM; SYNTHESIS;

AMIDES; ANTIHYPERTENSIVE AGENTS; FUMARATES; HYPERTENSION; PROTEASE INHIBITORS; RENIN; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 77951192304     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol100427v     Document Type: Article

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