Crystal structure of a cisplatin-(1,3-GTG) cross-link within DNA polymerase η

Angewandte Chemie - International Edition

Volumn 49, Issue 17, 2010, Pages 3077-3080

  Reißner, Thomas ^a   Schneider, Sabine ^a   Schorr, Stephanie ^a   Carell, Thomas ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Antitumor agents; Cisplatin; DNA damage; Polymerases; Translesion synthesis

Indexed keywords

ANTI-TUMOR AGENTS; CIS-PLATIN; CRYSTAL STRUCTURE DATA; CYTOTOXIC; DNA DAMAGES; DNA DUPLEXES; DNA LESIONS; DNA POLYMERASE; DNA-PROTEIN COMPLEXES; TRANSLESION SYNTHESIS;

DNA; FUNCTIONAL POLYMERS; GENES; PLATINUM COMPOUNDS; POLYMERS;

CRYSTAL STRUCTURE;

ANTINEOPLASTIC AGENT; CISPLATIN; CROSS LINKING REAGENT; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ETA;

ARTICLE; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; NEOPLASM; SACCHAROMYCES CEREVISIAE; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; CISPLATIN; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; DNA-DIRECTED DNA POLYMERASE; HUMANS; NEOPLASMS; SACCHAROMYCES CEREVISIAE;

EID: 77951169588     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201000414     Document Type: Article

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