Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells

Cardiovascular Pathology

Volumn 19, Issue 6, 2010, Pages

  Wong, Janica C ^a,b,c   Fiscus, Ronald R ^a,b,c,d  

^a NEVADA CANCER INSTITUTE   (United States)

^b UNIVERSITY OF NEVADA   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d ROSEMAN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

Apoptosis; DNA synthesis; Nitric oxide; Proliferation; Protein kinase G; Vascular smooth muscle cells

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ATRIAL NATRIURETIC FACTOR; BROXURIDINE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE ALPHA; CYCLIC GMP DEPENDENT PROTEIN KINASE BETA; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; DNA; DT 2; DT 3; ISOPROTEIN; KT 5823; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; ATHEROGENESIS; CELL COUNT; CELL CULTURE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME ACTIVATORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; MICE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; PROTEIN KINASE INHIBITORS; TIME FACTORS;

EID: 77951172906     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carpath.2009.11.001     Document Type: Article

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