Quantitative analysis of the cardiac fibroblast transcriptome - Implications for NO/cGMP signaling

Genomics

Volumn 83, Issue 4, 2004, Pages 577-587

  Smolenski, Albert ^a   Schultess, Jan ^a   Danielewski, Oliver ^a   Garcia Arguinzonis, Maisa I ^b   Thalheimer, Petra ^b   Kneitz, Susanne ^b   Walter, Ulrich ^b   Lohmann, Suzanne M ^b  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cardiac fibroblast; cGMP; Gene expression; Proliferation; Protein kinase; SAGE

Indexed keywords

COLLAGEN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GROWTH FACTOR; GUANYLATE CYCLASE; MATRIX PROTEIN; MESSENGER RNA; METALLOPROTEINASE; NITRIC OXIDE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSDUCTION; HEART MUSCLE CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERIAL ANALYSIS OF GENE EXPRESSION; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; WESTERN BLOTTING;

ANIMALS; BLOTTING, NORTHERN; CARRIER PROTEINS; CELL DIVISION; CYCLIC GMP; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GUANYLATE CYCLASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MYOCARDIUM; NITRIC OXIDE; PROTEOME; RECEPTORS, PEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

SALVIA;

EID: 1542719065     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ygeno.2003.10.002     Document Type: Article

References (48)

1. Weber K.T., Brilla C.G. Pathological hypertrophy and cardiac interstitium: fibrosis and renin-angiotensin-aldosterone system. Circulation. 83:1991;1849-1865.
2. Swynghedauw B. Molecular mechanisms of myocardial remodeling. Physiol. Rev. 79:1999;215-262.
3. Long C.S., Brown R.D. The cardiac fibroblast, another therapeutic target for mending the broken heart? J. Mol. Cell. Cardiol. 34:2002;1273-1278.
4. Schorb W., Booz G.W., Dostal D.E., Conrad K.M., Chang K.C., Baker K.M. Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts. Circ. Res. 72:1993;1245-1254.
5. Villarreal F.J., Kim N.N., Ungab G.D., Printz M.P., Dillmann W.H. Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation. 88:1993;2849-2861.
6. Tsutsumi Y., Matsubara H., Ohkubo N., Mori Y., Nozawa Y., Murasawa S., Kijima K., Maruyama K., Masaki H., Moriguchi Y., Shibasaki Y., Kamihata H., Inada M., Iwasaka T. Angiotensin II type 2 receptor is upregulated in human heart with interstitial fibrosis, and cardiac fibroblasts are the major cell type for its expression. Circ. Res. 83:1998;1035-1046.
7. Bouzegrhane F., Thibault G. Is angiotensin II a proliferative factor of cardiac fibroblasts? Cardiovasc Res. 53:2002;304-312.
8. Kuwahara F., Kai H., Tokuda K., Kai M., Takeshita A., Egashira K., Imaizumi T. Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats. Circulation. 106:2002;130-135.
9. Nakajima H., Nakajima H.O., Salcher O., Dittie A.S., Dembowsky K., Jing S., Field L.J. Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factor-beta(1) transgene in the heart. Circ. Res. 86:2000;571-579.
10. Akiyama-Uchida Y., Ashizawa N., Ohtsuru A., Seto S., Tsukazaki T., Kikuchi H., Yamashita S., Yano K. Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts. Hypertension. 40:2002;148-154.
11. Tsuruda T., Jougasaki M., Boerrigter G., Huntley B.K., Chen H.H., D'Assoro A.B., Lee S.C., Larsen A.M., Cataliotti A., Burnett J.C. Jr. Cardiotrophin-1 stimulation of cardiac fibroblast growth: roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor. Circ. Res. 90:2002;128-134.
12. Tamura N., Ogawa Y., Chusho H., Nakamura K., Nakao K., Suda M., Kasahara M., Hashimoto R., Katsuura G., Mukoyama M., Itoh H., Saito Y., Tanaka I., Otani H., Katsuki M. Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc. Natl. Acad. Sci. USA. 97:2000;4239-4244.
13. Vidal M. A biological atlas of functional maps. Cell. 104:2001;333-339.
14. Velculescu V.E., Zhang L., Vogelstein B., Kinzler K.W. Serial analysis of gene expression. Science. 270:1995;484-487.
15. Velculescu V.E., Zhang L., Zhou W., Vogelstein J., Basrai M.A., Bassett D.E. Jr., Hieter P., Vogelstein B., Kinzler K.W. Characterization of the yeast transcriptome. Cell. 88:1997;243-251.
16. Iyer V.R., Eisen M.B., Ross D.T., Schuler G., Moore T., Lee J.C., Trent J.M., Staudt L.M., Hudson J. Jr., Boguski M.S., Lashkari D., Shalon D., Botstein D., Brown P.O. The transcriptional program in the response of human fibroblasts to serum. Science. 283:1999;83-87.
17. Lal A., Lash A.E., Altschul S.F., Velculescu V., Zhang L., McLendon R.E., Marra M.A., Prange C., Morin P.J., Polyak K., Papadopoulos N., Vogelstein B., Kinzler K.W., Strausberg R.L., Riggins G.J. A public database for gene expression in human cancers. Cancer Res. 59:1999;5403-5407.
18. Velculescu V.E., Vogelstein B., Kinzler K.W. Analysing uncharted transcriptomes with SAGE. Trends Genet. 16:2000;423-425.
19. Robert-Nicoud M., Flahaut M., Elalouf J.M., Nicod M., Salinas M., Bens M., Doucet A., Wincker P., Artiguenave F., Horisberger J.D., Vandewalle A., Rossier B.C., Firsov D. Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin. Proc. Natl. Acad. Sci. USA. 98:2001;2712-2716.
20. Anisimov S., Tarasov K., Stern M., Lakatta E., Boheler K. A quantitative and validated SAGE transcriptome reference for adult mouse heart. Genomics. 80:2002;213.
21. Strissel K.J., Girard M.T., West-Mays J.A., Rinehart W.B., Cook J.R., Brinckerhoff C.E., Fini M.E. Role of serum amyloid A as an intermediate in the IL-1 and PMA-stimulated signaling pathways regulating expression of rabbit fibroblast collagenase. Exp. Cell Res. 237:1997;275-287.
22. Satoh J., Kuroda Y., Katamine S. Gene expression profile in prion protein-deficient fibroblasts in culture. Am. J. Pathol. 157:2000;59-68.
23. Bradshaw A.D., Sage E.H. SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J. Clin. Invest. 107:2001;1049-1054.
24. Nagase H., Woessner J.F. Jr. Matrix metalloproteinases. J. Biol. Chem. 274:1999;21491-21494.
25. Li P.F., Dietz R., von Harsdorf R. Superoxide induces apoptosis in cardiomyocytes, but proliferation and expression of transforming growth factor-beta1 in cardiac fibroblasts. FEBS Lett. 448:1999;206-210.
26. Ihn H. Pathogenesis of fibrosis: role of TGF-beta and CTGF. Curr. Opin. Rheumatol. 14:2002;681-685.
27. Wang S., Wu X., Lincoln T.M., Murphy-Ullrich J.E. Expression of constitutively active cGMP-dependent protein kinase prevents glucose stimulation of thrombospondin 1 expression and TGF-beta activity. Diabetes. 52:2003;2144-2150.
28. Gustafsson A.B., Brunton L.L. Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2. Am. J. Physiol. Cell. Physiol. 283:2002;C463-C471.
29. Waterston R.H., Lindblad-Toh K., Birney E., Rogers J., Abril J.F., Agarwal P., Agarwala R., Ainscough R., Alexandersson M., An P., Antonarakis S.E., Attwood J., Baertsch R., Bailey J., Barlow K.et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420:2002;520-562.
30. Yuasa K., Omori K., Yanaka N. Binding and phosphorylation of a novel male germ cell-specific cGMP-dependent protein kinase-anchoring protein by cGMP-dependent protein kinase Ialpha. J. Biol. Chem. 275:2000;4897-4905.
31. Lohmann S.M., Vaandrager A.B., Smolenski A., Walter U., De Jonge H.R. Distinct and specific functions of cGMP-dependent protein kinases. Trends. Biochem. Sci. 22:1997;307-312.
32. Cao L., Gardner D.G. Natriuretic peptides inhibit DNA synthesis in cardiac fibroblasts. Hypertension. 25:1995;227-234.
33. Fujisaki H., Ito H., Hirata Y., Tanaka M., Hata M., Lin M., Adachi S., Akimoto H., Marumo F., Hiroe M. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J. Clin. Invest. 96:1995;1059-1065.
34. Takizawa T., Gu M., Chobanian A.V., Brecher P. Effect of nitric oxide on DNA replication induced by angiotensin II in rat cardiac fibroblasts. Hypertension. 30:1997;1035-1040.
35. Calderone A., Thaik C.M., Takahashi N., Chang D.L., Colucci W.S. Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. J. Clin. Invest. 101:1998;812-818.
36. Chiche J.D., Schlutsmeyer S.M., Bloch D.B., de la Monte S.M., Roberts J.D. Jr., Filippov G., Janssens S.P., Rosenzweig A., Bloch K.D. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J. Biol. Chem. 273:1998;34263-34271.
37. Suhasini M., Li H., Lohmann S.M., Boss G.R., Pilz R.B. Cyclic-GMP-dependent protein kinase inhibits the Ras/mitogen-activated protein kinase pathway. Mol. Cell. Biol. 18:1998;6983-6994.
38. Hanada S., Terada Y., Inoshita S., Sasaki S., Lohmann S.M., Smolenski A., Marumo F. Overexpression of protein kinase G using adenovirus inhibits cyclin E transcription and mesangial cell cycle. Am. J. Physiol. Renal Physiol. 280:2001;F851-F859.
39. Fischer T.A., Palmetshofer A., Gambaryan S., Butt E., Jassoy C., Walter U., Sopper S., Lohmann S.M. Activation of cGMP-dependent protein kinase Ibeta inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells. J. Biol. Chem. 276:2001;5967-5974.
40. Marienfeld U., Walter U., Simm A. Inhibition of rat cardiac fibroblast growth by cAMP - but not by cGMP-dependent protein kinase. Basic Res. Cardiol. 96:2001;184-191.
41. Butt E., Gambaryan S., Gottfert N., Galler A., Marcus K., Meyer H.E. Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146. J. Biol. Chem. 278:2003;15601-15607.
42. Fujii M., Ogata T., Takahashi E., Yamada K., Nakabayashi K., Oishi M., Ayusawa D. Expression of the human cGMP-dependent protein kinase II gene is lost upon introduction of SV40 T antigen or immortalization in human cells. FEBS Lett. 375:1995;263-267.
43. Chen J., Sun M., Lee S., Zhou G., Rowley J.D., Wang S.M. Identifying novel transcripts and novel genes in the human genome by using novel SAGE tags. Proc. Natl. Acad. Sci. USA. 99:2002;12257-12262.
44. Ishii M., Hashimoto S., Tsutsumi S., Wada Y., Matsushima K., Kodama T., Aburatani H. Direct comparison of GeneChip and SAGE on the quantitative accuracy in transcript profiling analysis. Genomics. 68:2000;136-143.
45. Brazma A., Hingamp P., Quackenbush J., Sherlock G., Spellman P., Stoeckert C., Aach J., Ansorge W., Ball C.A., Causton H.C., Gaasterland T., Glenisson P., Holstege F.C., Kim I.F., Markowitz V., Matese J.C., Parkinson H., Robinson A., Sarkans U., Schulze-Kremer S., Stewart J., Taylor R., Vilo J., Vingron M. Minimum information about a microarray experiment (MIAME) - toward standards for microarray data. Nat. Genet. 29:2001;365-371.
46. Garcia Arguinzonis M.I., Galler A.B., Walter U., Reinhard M., Simm A. Increased spreading, Rac/p21-activated kinase (PAK) activity, and compromised cell motility in cells deficient in vasodilator-stimulated phosphoprotein (VASP). J. Biol. Chem. 277:2002;45604-45610.
47. Markert T., Vaandrager A.B., Gambaryan S., Pohler D., Hausler C., Walter U., De Jonge H.R., Jarchau T., Lohmann S.M. Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine: implications for cystic fibrosis transmembrane conductance regulator. J. Clin. Invest. 96:1995;822-830.
48. Smolenski A., Bachmann C., Reinhard K., Hönig-Liedl P., Jarchau T., Hoschuetzky H., Walter U. Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody. J. Biol. Chem. 273:1998;20029-20035.