-
1
-
-
0032919074
-
L'«épidémie» des maladies métaboliques, un problème majeur de santé publique
-
Scheen AJ. - L'«épidémie» des maladies métaboliques, un problème majeur de santé publique. Rev Med Liège, 1999, 54, 87-94.
-
(1999)
Rev. Med. Liège
, vol.54
, pp. 87-94
-
-
Scheen, A.J.1
-
2
-
-
31744443753
-
Is visceral obesity the cause of the metabolic syndrome?
-
Després JP. - Is visceral obesity the cause of the metabolic syndrome? Ann Med, 2006, 38, 52-63.
-
(2006)
Ann. Med.
, vol.38
, pp. 52-63
-
-
Després, J.P.1
-
3
-
-
0033776719
-
Obesity and cortisol
-
Björntorp P, Rosmond R. - Obesity and cortisol. Nutrition, 2000, 16, 924-936.
-
(2000)
Nutrition
, vol.16
, pp. 924-936
-
-
Björntorp, P.1
Rosmond, R.2
-
4
-
-
68549139946
-
The pathogenetic role of cortisol in the metabolic syndrome: A hypothesis
-
Anagnostis P, Athyros VG, Tziomalos K, et al. - The pathogenetic role of cortisol in the metabolic syndrome: A hypothesis. J Clin Endocrinol Metab, 2009, 94, 2692-2701.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2692-2701
-
-
Anagnostis, P.1
Athyros, V.G.2
Tziomalos, K.3
-
5
-
-
4043077286
-
11β-hydroxysteroïd dehydrogenase type 1: A tissue-specific regulator of glucocorticoid response
-
Tomlinson J W, Walker EA, Bujalska IJ, et al. - 11β- hydroxysteroïd dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev, 2004, 25, 831-866.
-
(2004)
Endocr Rev.
, vol.25
, pp. 831-866
-
-
Tomlinson, J.W.1
Walker, E.A.2
Bujalska, I.J.3
-
6
-
-
18844438379
-
Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydoxysteroid dehydrogenase type 1
-
Bujalska IJ, Draper N, Michailidou Z, et al. - Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydoxysteroid dehydrogenase type 1. J Mol Endocrinol, 2005, 34, 675-684.
-
(2005)
J. Mol. Endocrinol.
, vol.34
, pp. 675-684
-
-
Bujalska, I.J.1
Draper, N.2
Michailidou, Z.3
-
7
-
-
0036959901
-
A switch in dehydrogenase to reductase activity of 11β- hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells
-
Bujalska IJ, Walker EA, Hewison M, et al. - A switch in dehydrogenase to reductase activity of 11β-hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells. J Clin Endocrinol Metab, 2002, 87, 1205-1210.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1205-1210
-
-
Bujalska, I.J.1
Walker, E.A.2
Hewison, M.3
-
8
-
-
0942290504
-
11β-hydroxysteroid dehy-drogenase type 1 in obesity and type 2 diabetes
-
Stulnig TM, Waldhäusl W. - 11β-hydroxysteroid dehy-drogenase type 1 in obesity and type 2 diabetes. Diabe-tologia, 2004, 47, 1-11.
-
(2004)
Diabe-tologia
, vol.47
, pp. 1-11
-
-
Stulnig, T.M.1
Waldhäusl, W.2
-
9
-
-
76149111586
-
Rôle de l'enzyme 11β-hydroxystéroïde déshydrogénase de type 1 dans le risque métabolique associé à l'obésité
-
Iovino A, Paquot N, Scheen AJ. - Rôle de l'enzyme 11β-hydroxystéroïde déshydrogénase de type 1 dans le risque métabolique associé à l'obésité. Obésité, 2009, 4, 181-188.
-
(2009)
Obésité
, vol.4
, pp. 181-188
-
-
Iovino, A.1
Paquot, N.2
Scheen, A.J.3
-
10
-
-
33845644003
-
Tissue production of cortisol by 11β-hydroxysteroid dehydrogenase type 1 and metabolic disease
-
Walker BR, Andrew R. - Tissue production of cortisol by 11β-hydroxysteroid dehydrogenase type 1 and metabolic disease. Ann NY Acad Sci, 2006, 1083, 165-184.
-
(2006)
Ann. NY Acad. Sci.
, vol.1083
, pp. 165-184
-
-
Walker, B.R.1
Andrew, R.2
-
11
-
-
67651015402
-
Diet and the role of 11β-hydroxysteroid dehydrogenase-1 on obesity
-
London E, Castonguay TW. - Diet and the role of 11β-hydroxysteroid dehydrogenase-1 on obesity. J Nutr Biochem, 2009, 20, 485-493.
-
(2009)
J. Nutr. Biochem.
, vol.20
, pp. 485-493
-
-
London, E.1
Castonguay, T.W.2
-
12
-
-
39849090597
-
Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11β-hydroxysteroid dehydrogenase type 1) gene
-
Iwasaki Y, Takayasu S, Nishiyama M, et al. - Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11β-hydroxysteroid dehydrogenase type 1) gene. Mol Cell Endocrinol, 2008, 285, 10-18.
-
(2008)
Mol. Cell. Endocrinol.
, vol.285
, pp. 10-18
-
-
Iwasaki, Y.1
Takayasu, S.2
Nishiyama, M.3
-
13
-
-
77951055741
-
ère partie: Rôle de l'exposition tissulaire au cortisol dans le risque métabolique lié à l'obésité
-
-, sous presse
-
ère partie: rôle de l'exposition tissulaire au cortisol dans le risque métabolique lié à l'obésité. Méd Malad Métab, 2010, 4, sous presse.
-
(2010)
Méd Malad Métab
, vol.4
-
-
Iovino, A.1
Scheen, A.J.2
-
14
-
-
77951079891
-
ème partie: Inhibition sélec-tive pour traiter les anomalies métaboliques associées à l'obésité
-
-, sous presse
-
ème partie: Inhibition sélec-tive pour traiter les anomalies métaboliques associées à l'obésité. Méd Malad Métab, 2010, 4, sous presse.
-
(2010)
Méd Malad Métab
, vol.4
-
-
Iovino, A.1
Scheen, A.J.2
-
15
-
-
0030936556
-
Does central obesity reflect "Cushing's disease of the omentum"?
-
Bujalska IJ, Kumar S, Stewart PM. - Does central obesity reflect "Cushing's disease of the omentum"? Lancet, 1997, 349, 1210-1213.
-
(1997)
Lancet
, vol.349
, pp. 1210-1213
-
-
Bujalska, I.J.1
Kumar, S.2
Stewart, P.M.3
-
16
-
-
1942520410
-
«Cushing's disease of the omentum» fact or fiction?
-
Tomlinson J W, Stewart PM. - «Cushing's disease of the omentum» fact or fiction? J Endocrinol Invest, 2004, 27, 171-174.
-
(2004)
J. Endocrinol. Invest.
, vol.27
, pp. 171-174
-
-
Tomlinson, J.W.1
Stewart, P.M.2
-
17
-
-
63249083541
-
Cortisol release from adipose tissue by 11β-hydroxysteroid dehy-drogenase type 1 in humans
-
Stimson RH, Andersson J, Andrew R, et al. - Cortisol release from adipose tissue by 11β-hydroxysteroid dehy-drogenase type 1 in humans. Diabetes, 2009, 58, 46-53.
-
(2009)
Diabetes
, vol.58
, pp. 46-53
-
-
Stimson, R.H.1
Andersson, J.2
Andrew, R.3
-
18
-
-
53549105499
-
11beta-hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets
-
Swali A, Walker EA, Lavery GG, et al. - 11beta-hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets. Diabetolo-gia, 2008, 51, 2003-2011.
-
(2008)
Diabetolo-gia
, vol.51
, pp. 2003-2011
-
-
Swali, A.1
Walker, E.A.2
Lavery, G.G.3
-
19
-
-
67349178689
-
Additive action of 11beta-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats
-
Berthiaume M, Laplante M, Festuccia WT, et al. - Additive action of 11beta-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats. Int J Obes, 2009, 33, 601-604.
-
(2009)
Int. J. Obes.
, vol.33
, pp. 601-604
-
-
Berthiaume, M.1
Laplante, M.2
Festuccia, W.T.3
-
20
-
-
73949158787
-
Overex-pression of 11beta-hydroxysteroid dehydrogenase type 1 in hepatic and visceral adipose tissue is associated with metabolic disorders in morbidly obese patients
-
Baudrand R, Carvajal CA, Riquelme A, et al. - Overex-pression of 11beta-hydroxysteroid dehydrogenase type 1 in hepatic and visceral adipose tissue is associated with metabolic disorders in morbidly obese patients. Obes Surg, 2010, 20, 77-83.
-
(2010)
Obes. Surg.
, vol.20
, pp. 77-83
-
-
Baudrand, R.1
Carvajal, C.A.2
Riquelme, A.3
-
21
-
-
0035051205
-
Tissue-specific dysregulation of cortisol metabolism in human obesity
-
Rask E, Olsson T, Söderberg S, et al. - Tissue-specific dysregulation of cortisol metabolism in human obesity. J Clin Endocrinol Metab, 2001, 86, 1418-1421.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1418-1421
-
-
Rask, E.1
Olsson, T.2
Söderberg, S.3
-
22
-
-
0032990860
-
Cortisol metabolism in human obesity: Impaired cortisone cortisol conversion in subjects with central adiposity
-
Stewart PM, Boulton A, Kumar S, et al. - Cortisol metabolism in human obesity: impaired cortisone cortisol conversion in subjects with central adiposity. J Clin Endocrinol Metab, 1999, 84, 1022-1027.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1022-1027
-
-
Stewart, P.M.1
Boulton, A.2
Kumar, S.3
-
23
-
-
0036324073
-
Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11β-hydroxysteroid dehydro-genase type 1 activity
-
Rask E, Walker BR, Söderberg S, et al. - Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11β-hydroxysteroid dehydro-genase type 1 activity. J Clin Endocrinol Metab, 2002, 87, 3330-3336.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 3330-3336
-
-
Rask, E.1
Walker, B.R.2
Söderberg, S.3
-
24
-
-
36448973807
-
Type 2 diabetes and metabolic syndrome are associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in obese subjects
-
Alberti L, Girola A, Gilardini L, et al. - Type 2 diabetes and metabolic syndrome are associated with increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in obese subjects. Int J Obes, 2007, 31, 1826-1831.
-
(2007)
Int. J. Obes.
, vol.31
, pp. 1826-1831
-
-
Alberti, L.1
Girola, A.2
Gilardini, L.3
-
25
-
-
69949092969
-
Omental adipose tissue 11{beta}-HSD1 oxoreductase activity, body fat distribution and metabolic alterations in women
-
Veilleux A, Rhéaume C, Daris M, et al. - Omental adipose tissue 11{beta}-HSD1 oxoreductase activity, body fat distribution and metabolic alterations in women. J Clin Endocrinol Metab, 2009, 94, 3550-3557.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 3550-3557
-
-
Veilleux, A.1
Rhéaume, C.2
Daris, M.3
-
26
-
-
14644388141
-
Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone
-
Sandeep TC, Andrew R, Homer N Z M, et al. - Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. Diabetes, 2005, 54, 872-879.
-
(2005)
Diabetes
, vol.54
, pp. 872-879
-
-
Sandeep, T.C.1
Andrew, R.2
Homer, N.Z.M.3
-
27
-
-
23044460294
-
Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans
-
Basu R, Singh RJ, Basu A, et al. - Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans. J Clin Endocrinol Metab, 2005, 90, 3919-3926.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 3919-3926
-
-
Basu, R.1
Singh, R.J.2
Basu, A.3
-
28
-
-
63249083541
-
Cortisol release from adipose tissue by 11β-hydroxysteroid dehy-drogenase type 1 in humans
-
Stimson RH, Andersson J, Andrew R, et al. - Cortisol release from adipose tissue by 11β-hydroxysteroid dehy-drogenase type 1 in humans. Diabetes, 2009, 58, 46-53.
-
(2009)
Diabetes
, vol.58
, pp. 46-53
-
-
Stimson, R.H.1
Andersson, J.2
Andrew, R.3
-
29
-
-
17844363297
-
The contribution of visceral adipose tissue to splanchnic corti-sol production in healthy humans
-
Andrew R, Westerbacka J, Wahren J, et al. - The contribution of visceral adipose tissue to splanchnic corti-sol production in healthy humans. Diabetes, 2005, 54, 1364-1370.
-
(2005)
Diabetes
, vol.54
, pp. 1364-1370
-
-
Andrew, R.1
Westerbacka, J.2
Wahren, J.3
-
30
-
-
63249128191
-
Liver is the site of splanchnic cortisol production in obese nondiabetic humans
-
Basu R, Basu A, Grudzien M, et al. - Liver is the site of splanchnic cortisol production in obese nondiabetic humans. Diabetes, 2009, 58, 39-45.
-
(2009)
Diabetes
, vol.58
, pp. 39-45
-
-
Basu, R.1
Basu, A.2
Grudzien, M.3
-
31
-
-
63249113536
-
Selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome, is the target liver, fat, or both? (commentary)
-
Stewart PM, Tomlinson JW. - Selective inhibitors of 11β- hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome, is the target liver, fat, or both? (commentary). Diabetes, 2009, 58, 14-15.
-
(2009)
Diabetes
, vol.58
, pp. 14-15
-
-
Stewart, P.M.1
Tomlinson, J.W.2
-
32
-
-
4544263736
-
11β-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus
-
Valsamakis G, Anwar A, Tomlinson JW, et al. - 11β-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus. J Clin Endocrinol Metab, 2004, 89, 4755-4761.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 4755-4761
-
-
Valsamakis, G.1
Anwar, A.2
Tomlinson, J.W.3
-
33
-
-
67649362287
-
11beta-hydroxysteroid dehy-drogenase type 1 inhibitors: A review of recent patents
-
Boyle CD, Kowalski TJ. - 11beta-hydroxysteroid dehy-drogenase type 1 inhibitors: a review of recent patents. Exp Opin Ther Pat, 2009, 19, 801-825.
-
(2009)
Exp. Opin. Ther. Pat
, vol.19
, pp. 801-825
-
-
Boyle, C.D.1
Kowalski, T.J.2
-
34
-
-
64549162134
-
INCB013739, a selective inhibitor of 11β-hydroxysteroid dehydroge-nase type 1 (11βHSD1), improves insulin sensitivity and lowers plasma cholesterol over 28 days in patients with type 2 diabetes mellitus (Abstract)
-
Hawkins M, Hunter D, Kishore P, et al. - INCB013739, a selective inhibitor of 11β-hydroxysteroid dehydroge-nase type 1 (11βHSD1), improves insulin sensitivity and lowers plasma cholesterol over 28 days in patients with type 2 diabetes mellitus (Abstract). Diabetes, 2008, 57 (Suppl 1), A99-A100.
-
(2008)
Diabetes
, vol.57
, Issue.1 SUPPL.
-
-
Hawkins, M.1
Hunter, D.2
Kishore, P.3
-
35
-
-
73249122496
-
Efficacy and safety of the 11-β-HSD1 inhibitor, INCB13739, added to metformin therapy in patients with type 2 diabetes (abstract)
-
-, late breaking abstract 7-LB
-
Rosenstock J, Banarer S, Fonseca V, et al. - Efficacy and safety of the 11-β-HSD1 inhibitor, INCB13739, added to metformin therapy in patients with type 2 diabetes (abstract). Diabetes, 2009, 59, late breaking abstract 7-LB.
-
(2009)
Diabetes
, vol.59
-
-
Rosenstock, J.1
Banarer, S.2
Fonseca, V.3
-
36
-
-
39549104362
-
11β-hydroxystéroïde déshydrogénases. Avancées récentes
-
Vantyghem MC, Marcelli-Tourvieille S, Defrance F, et al. - 11β-hydroxystéroïde déshydrogénases. Avancées récentes. Ann Endocrinol Paris, 2007, 68, 349-356.
-
(2007)
Ann. Endocrinol. Paris
, vol.68
, pp. 349-356
-
-
Vantyghem, M.C.1
Marcelli-Tourvieille, S.2
Defrance, F.3
-
37
-
-
70350230403
-
HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia
-
Hwang JY, Lee SH, Kim GS, et al. - HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia. Bone, 2009, 45, 1098-1103.
-
(2009)
Bone
, vol.45
, pp. 1098-1103
-
-
Hwang, J.Y.1
Lee, S.H.2
Kim, G.S.3
-
38
-
-
34447105433
-
Inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target
-
Wamil M, Seckl JR. - Inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target. Drug Discov Today, 2007, 12, 504-520.
-
(2007)
Drug Discov Today
, vol.12
, pp. 504-520
-
-
Wamil, M.1
Seckl, J.R.2
-
39
-
-
65449167566
-
The role of metabolic derangements and glucocorticoid excess in the aetiology of cognitive impairment in type 2 diabetes
-
Strachan M W J, Reynolds RM, Frier BM, et al. - The role of metabolic derangements and glucocorticoid excess in the aetiology of cognitive impairment in type 2 diabetes. Implications for future therapeutic strategies. Diabetes Obes Metab, 2009, 11, 407-414.
-
(2009)
Implications for Future Therapeutic Strategies. Diabetes Obes. Metab.
, vol.11
, pp. 407-414
-
-
Strachan, M.W.J.1
Reynolds, R.M.2
Frier, B.M.3
|