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Volumn 58, Issue 1, 2009, Pages 14-15

Selective Inhibitors of 11 β-Hydroxysteroid Dehydrogenase Type 1 for Patients with Metabolic Syndrome: Is the Target Liver, Fat, or Both?

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 11BETA HYDROXYSTEROID DEHYDROGENASE 1 INHIBITOR; 11BETA HYDROXYSTEROID DEHYDROGENASE 2; ENZYME INHIBITOR; HYDROCORTISONE; UNCLASSIFIED DRUG;

EID: 63249113536     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1404     Document Type: Note
Times cited : (29)

References (12)
  • 6
    • 34249775822 scopus 로고    scopus 로고
    • Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1
    • Berthiaume M, Laplante M, Festuccia W, Gelinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y: Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1. Endocrinology 148:2391-2397, 2007
    • (2007) Endocrinology , vol.148 , pp. 2391-2397
    • Berthiaume, M.1    Laplante, M.2    Festuccia, W.3    Gelinas, Y.4    Poulin, S.5    Lalonde, J.6    Joanisse, D.R.7    Thieringer, R.8    Deshaies, Y.9
  • 7
    • 64549162134 scopus 로고    scopus 로고
    • INCB013739, a selective inhibitor of 11β-hydrox- ysteroid dehydrogenase type 1 (11βHSD1), improves insulin sensitivity and lowers plasma cholesterol over 28 days in patients with type 2 diabetes mellitus (Abstract)
    • Hawkins M, Hunter D, Kishore P, Schwartz S, Hompesch M, Hollis G, Levy R, Williams B, Huber R: INCB013739, a selective inhibitor of 11β-hydrox- ysteroid dehydrogenase type 1 (11βHSD1), improves insulin sensitivity and lowers plasma cholesterol over 28 days in patients with type 2 diabetes mellitus (Abstract). Diabetes 57 (Suppl. 1):A99-A100, 2008
    • (2008) Diabetes , vol.57 , Issue.SUPPL. 1
    • Hawkins, M.1    Hunter, D.2    Kishore, P.3    Schwartz, S.4    Hompesch, M.5    Hollis, G.6    Levy, R.7    Williams, B.8    Huber, R.9
  • 11
    • 33845539145 scopus 로고    scopus 로고
    • Splanchnic cortisol production in dogs occurs primarily in the liver: Evidence for substantial hepatic specific 11β hydroxysteroid dehydrogenase type 1 activity
    • Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA: Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11β hydroxysteroid dehydrogenase type 1 activity. Diabetes 55:3013-3019, 2006
    • (2006) Diabetes , vol.55 , pp. 3013-3019
    • Basu, R.1    Edgerton, D.S.2    Singh, R.J.3    Cherrington, A.4    Rizza, R.A.5
  • 12
    • 17844363297 scopus 로고    scopus 로고
    • The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans
    • Andrew R, Westerbacka J, Wahren J, Yki-Jarvinen H, Walker BR: The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans. Diabetes 54:1364-1370, 2005
    • (2005) Diabetes , vol.54 , pp. 1364-1370
    • Andrew, R.1    Westerbacka, J.2    Wahren, J.3    Yki-Jarvinen, H.4    Walker, B.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.