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Volumn 106, Issue 5, 2010, Pages 389-395

Regulation of low-density lipoprotein receptor and 3-hydroxy-3- methylglutaryl coenzyme A reductase expression by zingiber officinale in the liver of high-fat diet-fed rats

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CHOLESTEROL; GINGER EXTRACT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; ROSIGLITAZONE; TRIACYLGLYCEROL;

EID: 77951073882     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2009.00497.x     Document Type: Article
Times cited : (66)

References (48)
  • 1
    • 33645767027 scopus 로고    scopus 로고
    • Dietary cholesterol, atherosclerosis and coronary heart disease
    • Kratz M. Dietary cholesterol, atherosclerosis and coronary heart disease. Handb Exp Pharmacol 2005 170 : 195 213.
    • (2005) Handb Exp Pharmacol , vol.170 , pp. 195-213
    • Kratz, M.1
  • 2
    • 55849135236 scopus 로고    scopus 로고
    • Molecular processes that handle and mishandle dietary lipids
    • Williams KJ. Molecular processes that handle and mishandle dietary lipids. J Clin Invest 2008 118 : 3247 3259.
    • (2008) J Clin Invest , vol.118 , pp. 3247-3259
    • Williams, K.J.1
  • 3
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 1986 232 : 34 47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 4
    • 0026525973 scopus 로고
    • Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo
    • Rudling M. Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo. J Lipid Res 1992 33 : 493 501.
    • (1992) J Lipid Res , vol.33 , pp. 493-501
    • Rudling, M.1
  • 5
    • 0026755850 scopus 로고
    • Cholesterol biosynthesis and metabolism
    • Russell DW. Cholesterol biosynthesis and metabolism. Cardiovasc Drugs Ther 1992 6 : 103 110.
    • (1992) Cardiovasc Drugs Ther , vol.6 , pp. 103-110
    • Russell, D.W.1
  • 6
    • 0017354135 scopus 로고
    • The low-density lipoprotein pathway and its relation to atherosclerosis
    • Goldstein JL, Brown MS. The low-density lipoprotein pathway and its relation to atherosclerosis. Annu Rev Biochem 1977 46 : 897 930.
    • (1977) Annu Rev Biochem , vol.46 , pp. 897-930
    • Goldstein, J.L.1    Brown, M.S.2
  • 7
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990 343 : 425 430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 8
    • 33745590411 scopus 로고    scopus 로고
    • Acute P-407 administration to mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression
    • DOI 10.1007/s11095-006-0276-8
    • Leon C, Wasan KM, Sachs-Barrable K, Johnston TP. Acute P-407 administration of mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression. Pharm Res 2006 23 : 1597 1607. (Pubitemid 43993823)
    • (2006) Pharmaceutical Research , vol.23 , Issue.7 , pp. 1597-1607
    • Leon, C.1    Wasan, K.M.2    Sachs-Barrable, K.3    Johnston, T.P.4
  • 9
    • 33646790544 scopus 로고    scopus 로고
    • A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide- induced type 2 diabetes
    • Chen CW, Cheng HH. A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. J Nutr 2006 136 : 1472 1476.
    • (2006) J Nutr , vol.136 , pp. 1472-1476
    • Chen, C.W.1    Cheng, H.H.2
  • 10
    • 30744470901 scopus 로고    scopus 로고
    • Adzuki resistant starch lowered serum cholesterol and hepatic 3-hydroxy-3-methylglutaryl-CoA mRNA levels and increased hepatic LDL-receptor and cholesterol 7α-hydroxylase mRNA levels in the rats fed a cholesterol diet
    • DOI 10.1079/BJN20051598
    • Han KH, Iijuka M, Shimada K, Sekikawa M, Kuramochi K, Ohba K et al. Adzuki resistant starch lowered serum cholesterol and hepatic 3-hydroxy-3-methylglutaryl-CoA mRNA levels and increased hepatic LDL-receptor and cholesterol 7α-hydroxylse mRNA levels in rats fed a cholesterol diet. Brit J Nutr 2005 94 : 902 908. (Pubitemid 43092421)
    • (2005) British Journal of Nutrition , vol.94 , Issue.6 , pp. 902-908
    • Han, K.-H.1    Iijuka, M.2    Shimada, K.-I.3    Sekikawa, M.4    Kuramochi, K.5    Ohba, K.6    Ruvini, L.7    Chiji, H.8    Fukushima, M.9
  • 11
    • 34247532444 scopus 로고    scopus 로고
    • Hypocholesterolemic mechanism of Chlorella: Chlorella and its indigestible fraction enhance hepatic cholesterol catabolism through up-regulation of cholesterol 7α-hydroxylase in rats
    • DOI 10.1271/bbb.60566
    • Shibata S, Hayakawa K, Egashira Y, Sanada H. Hypocholesterolemic mechanism of Chlorella: Chlorella and its indigestible fraction enhance hepatic cholesterol catabolism through up-regulation of cholesterol 7 α -hydroxylase in rats. Biosci Biotechnol Biochem 2007 71 : 916 925. (Pubitemid 46650942)
    • (2007) Bioscience, Biotechnology and Biochemistry , vol.71 , Issue.4 , pp. 916-925
    • Shibata, S.1    Hayakawa, K.2    Egashira, Y.3    Sanada, H.4
  • 13
    • 23844530273 scopus 로고    scopus 로고
    • Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles
    • DOI 10.1016/j.phymed.2004.07.009, PII S0944711305001248
    • Chrubasik S, Pittler MH, Roufogalis BD. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 2005 12 : 684 701. (Pubitemid 41169818)
    • (2005) Phytomedicine , vol.12 , Issue.9 , pp. 684-701
    • Chrubasik, S.1    Pittler, M.H.2    Roufogalis, B.D.3
  • 14
    • 84972893056 scopus 로고
    • Ginger-chemistry technology and quality evaluation: Part-1
    • Govindarajan V. Ginger-chemistry technology and quality evaluation: Part-1. Crit Rev Food Sci Nutr 1982 17 : 1 96.
    • (1982) Crit Rev Food Sci Nutr , vol.17 , pp. 1-96
    • Govindarajan, V.1
  • 15
    • 0020448351 scopus 로고
    • Ginger-chemistry technology and quality evaluation: Part-2
    • Govindarajan V. Ginger-chemistry technology and quality evaluation: Part-2. Crit Rev Food Sci Nutr 1982 17 : 189 258.
    • (1982) Crit Rev Food Sci Nutr , vol.17 , pp. 189-258
    • Govindarajan, V.1
  • 16
    • 84970585046 scopus 로고
    • A re-examination of gingerol, shogaol and zingerone, the pungent principles of ginger (Zingiber officinale Roscoe)
    • Connell D, Sutherland M. A re-examination of gingerol, shogaol and zingerone, the pungent principles of ginger (Zingiber officinale Roscoe). Aust J Chem 1969 22 : 1033 1043.
    • (1969) Aust J Chem , vol.22 , pp. 1033-1043
    • Connell, D.1    Sutherland, M.2
  • 17
    • 0032101966 scopus 로고    scopus 로고
    • The protective action of ethanolic ginger extract in cholesterol-fed rabbits
    • Bhandari U, Sharma JN, Zafar R. The protective action of ethanolic ginger extract in cholesterol-fed rabbits. J Ethnopharmacol 1998 61 : 167 171.
    • (1998) J Ethnopharmacol , vol.61 , pp. 167-171
    • Bhandari, U.1    Sharma, J.N.2    Zafar, R.3
  • 18
    • 3042849117 scopus 로고    scopus 로고
    • Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits
    • Verma SK, Singh M, Jain P, Bordia A. Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits. Ind J Exp Biol 2004 42 : 736 738. (Pubitemid 38889467)
    • (2004) Indian Journal of Experimental Biology , vol.42 , Issue.7 , pp. 736-738
    • Verma, S.K.1    Singh, M.2    Jain, P.3    Bordia, A.4
  • 19
    • 13544263392 scopus 로고    scopus 로고
    • Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats
    • DOI 10.1016/j.jep.2004.11.011
    • Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol 2005 97 : 227 230. (Pubitemid 40222022)
    • (2005) Journal of Ethnopharmacology , vol.97 , Issue.2 , pp. 227-230
    • Bhandari, U.1    Kanojia, R.2    Pillai, K.K.3
  • 20
    • 0034011401 scopus 로고    scopus 로고
    • Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice
    • Fuhrman B, Rosenblat M, Hayek T, Coleman R, Aviram M. Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J Nutr 2000 130 : 1124 1131. (Pubitemid 30233257)
    • (2000) Journal of Nutrition , vol.130 , Issue.5 , pp. 1124-1131
    • Fuhrman, B.1    Rosenblat, M.2    Hayek, T.3    Coleman, R.4    Aviram, M.5
  • 22
    • 1042292667 scopus 로고    scopus 로고
    • Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats
    • DOI 10.1211/0022357022403
    • Akhani SP, Viswarkarma SL, Goyal RK. Antidiabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004 56 : 101 105. (Pubitemid 38195334)
    • (2004) Journal of Pharmacy and Pharmacology , vol.56 , Issue.1 , pp. 101-105
    • Akhani, S.P.1    Vishwakarma, S.L.2    Goyal, R.K.3
  • 23
    • 14044257722 scopus 로고    scopus 로고
    • Effect of an indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus
    • DOI 10.1002/ptr.1586
    • Sivakumar V, Sivakumar S. Effect of indigenous herbal compound preparation 'Trikatu' on the lipid profiles of atherogenic diet and standard diet fed Rattus norvegicus. Phytother Res 2004 18 : 976 981. (Pubitemid 40278921)
    • (2004) Phytotherapy Research , vol.18 , Issue.12 , pp. 976-981
    • Valsala, S.1    Sivakumar, S.2
  • 24
    • 0031196852 scopus 로고    scopus 로고
    • Biochemical studies on combined effects of garlic (Allium sativum Linn) and ginger (Zingiber officinale Rosc) in albino rats
    • Ahmed RS, Sharma SB. Biochemical studies on combined effects of garlic (Allium sativum Linn) and ginger (Zingiber officinale Rosc) in albino rats. Ind J Exp Biol 1997 35 : 841 843.
    • (1997) Ind J Exp Biol , vol.35 , pp. 841-843
    • Ahmed, R.S.1    Sharma, S.B.2
  • 25
    • 33646086967 scopus 로고    scopus 로고
    • Beneficial effects of Zingiber officinale on goldthioglucose induced obesity
    • Goyal RK, Kadnur S. Beneficial effects of Zingiber officinale on goldthioglucose induced obesity. Fitoterapia 2006 77 : 160 163.
    • (2006) Fitoterapia , vol.77 , pp. 160-163
    • Goyal, R.K.1    Kadnur, S.2
  • 26
    • 17244368760 scopus 로고    scopus 로고
    • Antiobesity actions of Zingiber officinale Roscoe
    • DOI 10.1248/yakushi.125.213
    • Han L, Gong X, Kawano S, Saito M, Kimura Y, Okuda H. Antiobesity actions of Zingiber officinale Roscoe. Yakugaku Zasshi 2005 125 : 213 217. (Pubitemid 40628411)
    • (2005) Yakugaku Zasshi , vol.125 , Issue.2 , pp. 213-217
    • Han, L.-K.1    Gong, X.-J.2    Kawano, S.3    Saito, M.4    Kimura, Y.5    Okuda, H.6
  • 27
    • 64549145497 scopus 로고    scopus 로고
    • Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet- fed rats
    • Nammi S, Sreemantula S, Roufogalis BD. Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet- fed rats. Basic Clin Pharmacol Toxicol 2009 104 : 366 373.
    • (2009) Basic Clin Pharmacol Toxicol , vol.104 , pp. 366-373
    • Nammi, S.1    Sreemantula, S.2    Roufogalis, B.D.3
  • 28
    • 0027309319 scopus 로고
    • Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe
    • Tanabe M, Chen YD, Saito KI, Kano Y. Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe. Chem Pharm Bull 1993 41 : 710 713. (Pubitemid 23166144)
    • (1993) Chemical and Pharmaceutical Bulletin , vol.41 , Issue.4 , pp. 710-713
    • Tanabe, M.1    Chen, Y.-D.2    Saito, K.3    Kano, Y.4
  • 29
    • 0026311501 scopus 로고
    • The effect of spices on cholesterol-7α-hydroxylase activity and on serum and hepatic cholesterol levels in the rat
    • Srinivasan K, Sambaiah K. The effect of spices on cholesterol-7α- hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Int J Vit Nutr Res 1991 61 : 364 369.
    • (1991) Int J Vit Nutr Res , vol.61 , pp. 364-369
    • Srinivasan, K.1    Sambaiah, K.2
  • 30
    • 26844499175 scopus 로고    scopus 로고
    • Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high-performance liquid chromatography/ electrospray ionization mass spectrometry
    • DOI 10.1002/rcm.2140
    • Jiang H, So′lyom AM, Timmermann BN, Gang DR. Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom 2005 19 : 2957 2964. (Pubitemid 41454614)
    • (2005) Rapid Communications in Mass Spectrometry , vol.19 , Issue.20 , pp. 2957-2964
    • Jiang, H.1    Solyom, A.M.2    Timmermann, B.N.3    Gang, D.R.4
  • 32
    • 34548119824 scopus 로고    scopus 로고
    • High-performance liquid chromatographic analysis of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in ginger-containing dietary supplements, spices, teas, and beverages
    • Schwertner HA, Rios DC. High-performance liquid chromatographic analysis of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in ginger-containing dietary supplements, spices, teas, and beverages. J Chromatogr B 2004 856 : 41 7.
    • (2004) J Chromatogr B , vol.856 , pp. 41-47
    • Schwertner, H.A.1    Rios, D.C.2
  • 33
    • 0018128226 scopus 로고
    • Lipid extraction of tissues with a low toxicity solvent
    • Hara A, Radin NS. Lipid extraction of tissues with a low-toxicity solvent. Anal Biochem 1978 90 : 420. (Pubitemid 9062124)
    • (1978) Analytical Biochemistry , vol.90 , Issue.1 , pp. 420-426
    • Hara, A.1    Radin, N.S.2
  • 34
    • 33747079056 scopus 로고    scopus 로고
    • A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose tolerance in mice fid a high-fat diet
    • Raubenheimer PJ, Nyirenda MJ, Walker BR. A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose tolerance in mice fid a high-fat diet. Diabetes 2006 55 : 2015 2020.
    • (2006) Diabetes , vol.55 , pp. 2015-2020
    • Raubenheimer, P.J.1    Nyirenda, M.J.2    Walker, B.R.3
  • 35
    • 4243098381 scopus 로고    scopus 로고
    • Dietary fat, insulin sensitivity and the metabolic syndrome
    • Riccardi G, Giacco R, Rivellese AA. Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 2007 23 : 447 456.
    • (2007) Clin Nutr , vol.23 , pp. 447-456
    • Riccardi, G.1    Giacco, R.2    Rivellese, A.A.3
  • 36
    • 0029558972 scopus 로고
    • Regulation of intracellular cholesterol metabolism
    • Sato R, Takano T. Regulation of intracellular cholesterol metabolism. Cell Struct Funct 1995 20 : 421 427. (Pubitemid 26061323)
    • (1995) Cell Structure and Function , vol.20 , Issue.6 , pp. 421-427
    • Sato, R.1    Takano, T.2
  • 37
    • 0035351005 scopus 로고    scopus 로고
    • Lipid lowering therapy in diabetes mellitus
    • Neimeijer-Kanters SDJM, Banga JD, Erkelens DW. Lipid lowering therapy in diabetes mellitus. Neth J Med 2001 58 : S14 9.
    • (2001) Neth J Med , vol.58 , pp. 14-19
    • Sdjm, N.1    Banga, J.D.2    Erkelens, D.W.3
  • 38
    • 34347394984 scopus 로고    scopus 로고
    • Management of dyslipidemia in the metabolic syndrome
    • Tan KC. Management of dyslipidemia in the metabolic syndrome. Cardiovasc Hematol Disord Targets 2007 7 : 99 108.
    • (2007) Cardiovasc Hematol Disord Targets , vol.7 , pp. 99-108
    • Tan, K.C.1
  • 39
    • 0030854557 scopus 로고    scopus 로고
    • Regulation of cholesterol biosynthesis by diet in humans
    • Jones PJ. Regulation of cholesterol biosynthesis by diet in humans. Am J Clin Nutr 1997 66 : 438 446.
    • (1997) Am J Clin Nutr , vol.66 , pp. 438-446
    • Jones, P.J.1
  • 40
    • 0025830753 scopus 로고
    • Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels
    • Ness GC, Keller RK, Pendleton LC. Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels. J Biol Chem 1991 266 : 14854 14857.
    • (1991) J Biol Chem , vol.266 , pp. 14854-14857
    • Ness, G.C.1    Keller, R.K.2    Pendleton, L.C.3
  • 41
    • 0032526825 scopus 로고    scopus 로고
    • Dietary cholesterol regulates hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in rats primarily at the level of translation
    • Chambers CM, Ness GC. Dietary cholesterol regulates hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in rats primarily at the level of translation. Arch Biochem Biophys 1998 354 : 317 322.
    • (1998) Arch Biochem Biophys , vol.354 , pp. 317-322
    • Chambers, C.M.1    Ness, G.C.2
  • 42
    • 0034093374 scopus 로고    scopus 로고
    • Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: The concept of cholesterol buffering capacity
    • Ness GC, Chambers CM. Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: the concept of cholesterol buffering capacity. Proc Soc Exp Biol Med 2000 224 : 8 19.
    • (2000) Proc Soc Exp Biol Med , vol.224 , pp. 8-19
    • Ness, G.C.1    Chambers, C.M.2
  • 43
    • 0024576223 scopus 로고
    • Regulation of low density lipoprotein receptor gene expression in human lymphocytes
    • Cuthbert JA, Russell DW, Lipsky PE. Regulation of low density lipoprotein receptor gene expression in human lymphocytes. J Biol Chem 1991 264 : 1298 1304.
    • (1991) J Biol Chem , vol.264 , pp. 1298-1304
    • Cuthbert, J.A.1    Russell, D.W.2    Lipsky, P.E.3
  • 44
    • 84989661353 scopus 로고
    • IGF i increases LDL receptor expression in fibroblasts by a posttranscriptional mechanism involving IGF I-receptors
    • Ostlund RE Jr., Iang JW, Heath-Monning E, Semenkovich CF, Daughaday WH. IGF I increases LDL receptor expression in fibroblasts by a posttranscriptional mechanism involving IGF I-receptors. Artm'osck Thromb 1991 11 : 1414.
    • (1991) Artm'Osck Thromb , vol.11 , pp. 1414
    • Ostlund Jr., R.E.1    Iang, J.W.2    Heath-Monning, E.3    Semenkovich, C.F.4    Daughaday, W.H.5
  • 45
    • 4244146024 scopus 로고
    • Dietary fat and cholesterol-induced modifications of LDL receptor function and mRNA abundance in nonhuman primates
    • Owen CH, Sorci-Thomas M, Rudel LL. Dietary fat and cholesterol-induced modifications of LDL receptor function and mRNA abundance in nonhuman primates. Artm'osck Thromb 1991 11 : 1447.
    • (1991) Artm'Osck Thromb , vol.11 , pp. 1447
    • Owen, C.H.1    Sorci-Thomas, M.2    Rudel, L.L.3
  • 46
    • 0021673438 scopus 로고
    • Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol
    • Goldstein JL, Brown MS. Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol. J Lipid Res 1984 25 : 1450 1461.
    • (1984) J Lipid Res , vol.25 , pp. 1450-1461
    • Goldstein, J.L.1    Brown, M.S.2
  • 47
    • 0026775156 scopus 로고
    • Regulation of hepatic sterol metabolism in the rat-parallel regulation of activity and messenger RNA for 7alpha-hydroxylase but not 3-hydroxy-3- methylglutaryl-coenzyme-A reductase or low density lipoprotein receptor
    • Spady DK, Cuthbert JA. Regulation of hepatic sterol metabolism in the rat-parallel regulation of activity and messenger RNA for 7alpha-hydroxylase but not 3-hydroxy-3-methylglutaryl-coenzyme-A reductase or low density lipoprotein receptor. J Biol Chem 1992 267 : 5584 5591.
    • (1992) J Biol Chem , vol.267 , pp. 5584-5591
    • Spady, D.K.1    Cuthbert, J.A.2
  • 48
    • 0028212483 scopus 로고
    • Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver
    • Powell EE, Kroon PA. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver. J Clin Invest 1994 93 : 2168 2174.
    • (1994) J Clin Invest , vol.93 , pp. 2168-2174
    • Powell, E.E.1    Kroon, P.A.2


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