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Volumn 23, Issue 7, 2006, Pages 1597-1607

Acute P-407 administration to mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression

Author keywords

Cellular cholesterol efflux; P 407 induced dyslipidemia; Reverse cholesterol transport

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G8; ACTIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; POLOXAMER; SCAVENGER RECEPTOR BI; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

EID: 33745590411     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-0276-8     Document Type: Article
Times cited : (35)

References (37)
  • 1
    • 0036851863 scopus 로고    scopus 로고
    • The liver X receptor gene team: Potential new players in atherosclerosis
    • J. J. Repa D. J. Mangelsdorf 2002 The liver X receptor gene team: potential new players in atherosclerosis Nat. Med. 8 1243 1248
    • (2002) Nat. Med. , vol.8 , pp. 1243-1248
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 2
    • 0028345073 scopus 로고
    • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
    • S. Ishibashi J. L. Goldstein M. S. Brown J. Herz D. K. Burns 1994 Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice J. Clin. Invest. 93 1885 1893
    • (1994) J. Clin. Invest. , vol.93 , pp. 1885-1893
    • Ishibashi, S.1    Goldstein, J.L.2    Brown, M.S.3    Herz, J.4    Burns, D.K.5
  • 3
    • 3042582763 scopus 로고    scopus 로고
    • The P-407-induced murine model of dose-controlled hyperlipidemia and atherosclerosis: A review of findings to date
    • T. P. Johnston 2004 The P-407-induced murine model of dose-controlled hyperlipidemia and atherosclerosis: a review of findings to date J. Cardiovasc. Pharmacol. 43 595 606
    • (2004) J. Cardiovasc. Pharmacol. , vol.43 , pp. 595-606
    • Johnston, T.P.1
  • 4
    • 24344490760 scopus 로고    scopus 로고
    • Determining hepatic triglyceride production in mice: Comparison of poloxamer 407 with Triton WR-1339
    • J. S. Millar D. A. Cromley M. G. [tmp] McCoy D. J. Rader J. T. Billheimer 2005 Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339 J. Lipid Res. 46 2023 2028
    • (2005) J. Lipid Res. , vol.46 , pp. 2023-2028
    • Millar, J.S.1    Cromley, D.A.2    McCoy, M.G.3    Rader, D.J.4    Billheimer, J.T.5
  • 5
    • 0033569331 scopus 로고    scopus 로고
    • Dose-dependent hyperlipidemia in rabbits following administration of poloxamer 407 gel
    • J. M. Blonder L. Baird J. C. Fulfs G. J. Rosenthal 1999 Dose-dependent hyperlipidemia in rabbits following administration of poloxamer 407 gel Life Sci. 65 L261 L266
    • (1999) Life Sci. , vol.65
    • Blonder, J.M.1    Baird, L.2    Fulfs, J.C.3    Rosenthal, G.J.4
  • 6
    • 31744447154 scopus 로고    scopus 로고
    • The effect of increased lipoprotein levels on the pharmacokinetics of cyclosporine a in the laboratory rat
    • D. R. Brocks S. Ala H. M. Aliabadi 2005 The effect of increased lipoprotein levels on the pharmacokinetics of cyclosporine A in the laboratory rat Biopharm. Drug Dispos. 27 7 16
    • (2005) Biopharm. Drug Dispos. , vol.27 , pp. 7-16
    • Brocks, D.R.1    Ala, S.2    Aliabadi, H.M.3
  • 8
    • 0031851403 scopus 로고    scopus 로고
    • Poloxamer 407-induced atherogenesis in the C57BL/6 mouse
    • W. K. Palmer E. E. Emeson T. P. Johnston 1998 Poloxamer 407-induced atherogenesis in the C57BL/6 mouse Atherosclerosis 136 115 123
    • (1998) Atherosclerosis , vol.136 , pp. 115-123
    • Palmer, W.K.1    Emeson, E.E.2    Johnston, T.P.3
  • 10
    • 0015847114 scopus 로고
    • Quantitative determination of serum triglycerides by the use of enzymes
    • G. Bucolo H. David 1973 Quantitative determination of serum triglycerides by the use of enzymes Clin. Chem. 19 476 482
    • (1973) Clin. Chem. , vol.19 , pp. 476-482
    • Bucolo, G.1    David, H.2
  • 11
    • 77957010585 scopus 로고
    • General procedures for separating lipid components of tissue
    • C. Entenman 1957 General procedures for separating lipid components of tissue Methods Enzymol. 3 301 313
    • (1957) Methods Enzymol. , vol.3 , pp. 301-313
    • Entenman, C.1
  • 12
    • 0034520194 scopus 로고    scopus 로고
    • Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
    • R. G. Lee M. C. Willingham M. A. Davis K. A. Skinner L. L. Rudel 2000 Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates J. Lipid Res. 41 1991 2001
    • (2000) J. Lipid Res. , vol.41 , pp. 1991-2001
    • Lee, R.G.1    Willingham, M.C.2    Davis, M.A.3    Skinner, K.A.4    Rudel, L.L.5
  • 13
    • 0037200030 scopus 로고    scopus 로고
    • Primates highly responsive to dietary cholesterol up-regulate hepatic ACAT2, and less responsive primates do not
    • L. L. Rudel M. Davis J. Sawyer R. Shah J. Wallace 2002 Primates highly responsive to dietary cholesterol up-regulate hepatic ACAT2, and less responsive primates do not J. Biol. Chem. 277 31401 31406
    • (2002) J. Biol. Chem. , vol.277 , pp. 31401-31406
    • Rudel, L.L.1    Davis, M.2    Sawyer, J.3    Shah, R.4    Wallace, J.5
  • 17
    • 33646033422 scopus 로고    scopus 로고
    • Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats
    • in press.
    • T. P. Johnston, M. Jaye, C. L. Webb, J. A. Krawiec, S. P. Alom-Ruiz, K. Sachs-Barrable, and K. M. Wasan. Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats. Eur. J. Pharmacol. (2006), in press.
    • (2006) Eur. J. Pharmacol.
    • Johnston, T.P.1    Jaye, M.2    Webb, C.L.3    Krawiec, J.A.4    Alom-Ruiz, S.P.5    Sachs-Barrable, K.6    Wasan, K.M.7
  • 18
    • 0141652926 scopus 로고    scopus 로고
    • Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats
    • K. M. Wasan R. Subramanian M. Kwong I. J. Goldberg T. Wright T. P. Johnston 2003 Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats J. Pharm. Sci. 6 189 197
    • (2003) J. Pharm. Sci. , vol.6 , pp. 189-197
    • Wasan, K.M.1    Subramanian, R.2    Kwong, M.3    Goldberg, I.J.4    Wright, T.5    Johnston, T.P.6
  • 19
    • 0032167947 scopus 로고    scopus 로고
    • Regulation of lecithin cholesterol acyltransferase activity
    • A. Jonas 1998 Regulation of lecithin cholesterol acyltransferase activity Prog. Lipid Res. 37 209 234
    • (1998) Prog. Lipid Res. , vol.37 , pp. 209-234
    • Jonas, A.1
  • 20
    • 0014264541 scopus 로고
    • The plasma lecithins:cholesterol acyltransferase reaction
    • J. A. Glomset 1968 The plasma lecithins:cholesterol acyltransferase reaction J. Lipid Res. 9 155 167
    • (1968) J. Lipid Res. , vol.9 , pp. 155-167
    • Glomset, J.A.1
  • 22
    • 0027182897 scopus 로고
    • Mechanism of poloxamer 407-induced hypertriglyceridemia in the rat
    • T. P. Johnston W. K. Palmer 1993 Mechanism of poloxamer 407-induced hypertriglyceridemia in the rat Biochem. Pharmacol. 46 1037 1042
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1037-1042
    • Johnston, T.P.1    Palmer, W.K.2
  • 26
    • 0035965514 scopus 로고    scopus 로고
    • Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis
    • T. P. Johnston L. B. Nguyen W. A. Chu 2001 Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis Int. J. Pharm. 229 75 86
    • (2001) Int. J. Pharm. , vol.229 , pp. 75-86
    • Johnston, T.P.1    Nguyen, L.B.2    Chu, W.A.3
  • 27
    • 0030978983 scopus 로고    scopus 로고
    • Effect of poloxamer 407 on the activity of microsomal 3-hydroxy-3-methylglutaryl CoA reductase in rats
    • T. P. Johnston W. K. Palmer 1997 Effect of poloxamer 407 on the activity of microsomal 3-hydroxy-3-methylglutaryl CoA reductase in rats J. Cardiovasc. Pharmacol. 29 580 585
    • (1997) J. Cardiovasc. Pharmacol. , vol.29 , pp. 580-585
    • Johnston, T.P.1    Palmer, W.K.2
  • 28
    • 0034099366 scopus 로고    scopus 로고
    • Regression of poloxamer 407-induced atherosclerotic lesions in C57BL/6 mice using atorvastatin
    • T. P. Johnston J. C. Baker D. Hall S. Jamal W. K. Palmer E. E. Emeson 2000 Regression of poloxamer 407-induced atherosclerotic lesions in C57BL/6 mice using atorvastatin Atherosclerosis 149 303 313
    • (2000) Atherosclerosis , vol.149 , pp. 303-313
    • Johnston, T.P.1    Baker, J.C.2    Hall, D.3    Jamal, S.4    Palmer, W.K.5    Emeson, E.E.6
  • 29
    • 0017724648 scopus 로고
    • Mechanism for elevation of hepatic cholesterol synthesis and serum cholesterol levels in triton WR-1339-induced hyperlipidemia
    • M. Kuroda K. Tanzawa Y. Tsujita A. Endo 1977 Mechanism for elevation of hepatic cholesterol synthesis and serum cholesterol levels in triton WR-1339-induced hyperlipidemia Biochim. Biophys. Acta 489 119 125
    • (1977) Biochim. Biophys. Acta , vol.489 , pp. 119-125
    • Kuroda, M.1    Tanzawa, K.2    Tsujita, Y.3    Endo, A.4
  • 30
    • 0017409666 scopus 로고
    • Regulation of sterol synthesis in 16 tissues of rat. I. Effect of diurnal light cycling, fasting, stress, manipulation of enterohepatic circulation, and administration of chylomicrons and triton
    • J. M. Andersen J. M. Dietschy 1977 Regulation of sterol synthesis in 16 tissues of rat. I. Effect of diurnal light cycling, fasting, stress, manipulation of enterohepatic circulation, and administration of chylomicrons and triton J. Biol. Chem. 252 3646 3651
    • (1977) J. Biol. Chem. , vol.252 , pp. 3646-3651
    • Andersen, J.M.1    Dietschy, J.M.2
  • 31
    • 84960962585 scopus 로고
    • Mechanism underlying hypercholesteremia induced by triton WR-1339
    • M. Friedman S. O. Byers 1957 Mechanism underlying hypercholesteremia induced by triton WR-1339 Am. J. Physiol. 190 439 445
    • (1957) Am. J. Physiol. , vol.190 , pp. 439-445
    • Friedman, M.1    Byers, S.O.2
  • 32
    • 0024449814 scopus 로고
    • Detergent induced changes in serum lipid composition in rats
    • Y. Miura H. Hisaki B. Fukushima T. Nagai T. Ikeda 1989 Detergent induced changes in serum lipid composition in rats Lipids 24 915 918
    • (1989) Lipids , vol.24 , pp. 915-918
    • Miura, Y.1    Hisaki, H.2    Fukushima, B.3    Nagai, T.4    Ikeda, T.5
  • 33
    • 0029008669 scopus 로고
    • Phase behavior of tyloxapol/Triton X100/water mixtures
    • K. Westensen H. Bunjes M. H. Koch 1995 Phase behavior of tyloxapol/Triton X100/water mixtures J. Pharm. Sci. 84 544 550
    • (1995) J. Pharm. Sci. , vol.84 , pp. 544-550
    • Westensen, K.1    Bunjes, H.2    Koch, M.H.3
  • 34
    • 0032883658 scopus 로고    scopus 로고
    • Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers
    • E. V. Batrakova S. Li D. W. Miller A. V. Kabanov 1999 Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers Pharm. Res. 16 1366 1372
    • (1999) Pharm. Res. , vol.16 , pp. 1366-1372
    • Batrakova, E.V.1    Li, S.2    Miller, D.W.3    Kabanov, A.V.4
  • 35
    • 17744382615 scopus 로고    scopus 로고
    • Effect of pluronic P85 on ATPase activity of drug efflux transporters
    • E. V. Batrakova S. Li Y. Li V. Y. Alakhov A. V. Kabanov 2004 Effect of pluronic P85 on ATPase activity of drug efflux transporters Pharm. Res. 21 2226 2233
    • (2004) Pharm. Res. , vol.21 , pp. 2226-2233
    • Batrakova, E.V.1    Li, S.2    Li, Y.3    Alakhov, V.Y.4    Kabanov, A.V.5
  • 36
    • 33745602106 scopus 로고    scopus 로고
    • Does P-glycoprotein play a role in gastrointestinal absorption and cellular transport of dietary cholesterol?
    • in press.
    • C. Leon, K. Sachs-Barrable, and K. M. Wasan. Does P-glycoprotein play a role in gastrointestinal absorption and cellular transport of dietary cholesterol? Drug Dev. Ind. Pharm. (2006), in press.
    • (2006) Drug Dev. Ind. Pharm.
    • Leon, C.1    Sachs-Barrable, K.2    Wasan, K.M.3
  • 37
    • 31844451628 scopus 로고    scopus 로고
    • Reevaluation of the role of the multidrug resistant P-glycoprotein in cellular cholesterol homeostasis
    • G. W. Le, M. Settle, D. J. Greene, R. E. Morton, and J. D. Smith. Reevaluation of the role of the multidrug resistant P-glycoprotein in cellular cholesterol homeostasis. J. Lipid Res. (2005).
    • (2005) J. Lipid Res.
    • Le, G.W.1    Settle, M.2    Greene, D.J.3    Morton, R.E.4    Smith, J.D.5


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