A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide- induced type 2 diabetes

Journal of Nutrition

Volumn 136, Issue 6, 2006, Pages 1472-1476

  Chen, Chia Wen ^a   Cheng, Hsing Hsien ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

HMG CoA reductase; Insulin sensitivity; LDL receptor; Rice bran oil; Type 2 diabetic rats

Indexed keywords

BILE ACID; CHOLESTEROL; EDIBLE OIL; GAMMA ORYZANOL; GAMMA TOCOTRIENOL; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; NICOTINAMIDE; STEROL; STREPTOZOCIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIETARY INTAKE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HYPERINSULINEMIA; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID COMPOSITION; LIVER WEIGHT; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; RAT; RICE BRAN; TRANSCRIPTION INITIATION; WEIGHT GAIN;

EID: 33646790544     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.6.1472     Document Type: Article

References (35)

1. Berger A, Rein D, Schafer A, Monnard I, Gremaud G, Lambelet P, Bertoli C. Similar cholesterol-lowering properties of rice bran oil, with varied gamma-oryzanol, in mildly hypercholesterolemic men. Eur J Nutr. 2005;44:163-73.
2. Most MM, Tulley R, Morales S, Lefevre M. Rice bran oil, not fiber, lowers cholesterol in humans. Am J Clin Nutr. 2005;81:64-8.
3. Purushothama S, Raina PL, Hariharan K. Effect of long-term feeding of rice bran oil upon lipids and lipoproteins in rats. Mol Cell Biochem. 1995;146:63-9.
4. Sakamoto K, Tabata T, Shirasaki K, Inagaki T, Nakayama S. Effects of gamma-oryzanol and cycloartenol ferulic acid ester on cholesterol diet induced hyperlipidemia in rats. Jpn J Pharmacol. 1987;45:559-65.
5. Fang N, Yu S, Badger TM. Characterization of triterpene alcohol and sterol ferulates in rice bran using LC-MS/MS. J Agric Food Chem. 2003;51:3260-7.
6. Seetharamaiah GS, Chandrasekhara N. Studies on hypocholesterolemic activity of rice bran oil. Atherosclerosis. 1989;78:219-23.
7. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993;268:11230-8.
8. Powell EE, Kroon PA. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver. J Clin Invest. 1994;93:2168-74.
9. Chiang JY. Bile acid regulation of gene expression: roles of nuclear hormone receptors. Endocr Rev. 2002;23:443-63.
10. Cheema SK, Agellon LB. The murine and human cholesterol 7alpha-hydroxylase gene promoters are differentially responsive to regulation by fatty acids mediated via peroxisome proliferator-activated receptor alpha. J Biol Chem. 2000;275:12530-6.
11. Dietschy JM, Turley SD, Spady DK. Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res. 1993;34:1637-59.
12. Masiello P, Broca C, Gross R, Roye M, Manteghetti M, Hillaire-Buys D, Novelli M, Ribes G. Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes. 1998;47:224-9.
13. 2 extract of Elettaria cardamomum (L.) Maton. J Agric Food Chem. 2004;52:6278-82.
14. Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939-51.
15. National Science Council. Guide for the care and use of laboratory animals. Taipei, Taiwan, ROC; 1994.
16. Qureshi AA, Mo H, Packer L, Peterson DM. Isolation and identification of novel tocotrienols from rice bran with hypocholesterolemic, antioxidant, and antitumor properties. J Agric Food Chem. 2000;48:3130-40.
17. Lepage G, Roy CC. Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res. 1986;27:114-20.
18. Belobrajdic DP, Mcintosh GH, Owens JA. A high-whey-protein diet reduces body weight gain and alters insulin sensitivity relative to red meat in Wistar rats. J Nutr. 2004;134:1454-8.
19. Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1957;226:497-509.
20. Mashige F, Tanaka N, Maki A, Kamei S, Yamanaka M. Direct spectrophotometry of total bile acids in serum. Clin Chem. 1981;27:1352-6.
21. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-9.
22. Powell EE, Kroon PA. Measurement of mRNA by quantitative PCR with a nonradioactive label. J Lipid Res. 1992;33:609-14.
23. Bloomgarden ZT. Cardiovascular disease and diabetes. Diabetes Care. 2003;26:230-7.
24. Ginsberg HN. Lipoprotein metabolism and its relationship to atherosclerosis. Med Clin North Am. 1994;78:1-20.
25. Norton RA. Quantitation of steryl ferulate and p-coumarate esters from corn and rice. Lipids. 1995;30:269-74.
26. Sasaki J, Takada Y, Handa K, Kusuda M, Tanabe Y, Matsunaga A, Arakawa K. Effects of gamma-oryzanol on serum lipids and apolipoproteins in dyslipidemic schizophrenics receiving major tranquilizers. Clin Ther. 1990;12:263-8.
27. Vissers MN, Zock PL, Meijer GW, Katan MB. Effect of plant sterols from rice bran oil and triterpene alcohols from sheanut oil on serum lipoprotein concentrations in humans. Am J Clin Nutr. 2000;72:1510-5.
28. Lim SY, Doherty JD, Salem N Jr. Lead exposure and (n-3) fatty acid deficiency during rat neonatal development alter liver, plasma, and brain polyunsaturated fatty acid composition. J Nutr. 2005;135:1027-33.
29. Brynes AE, Edwards CM, Jadhav A, Ghatei MA, Bloom SR, Frost GS. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. Am J Clin Nutr. 2000;72:1111-8.
30. Li Y, Hou MJ, Ma J, Tang ZH, Zhu HL, Ling WH. Dietary fatty acids regulate cholesterol induction of liver CYP7alpha1 expression and bile acid production. Lipids. 2005;40:455-62.
31. Rong N, Ausman LM, Nicolosi RJ. Oryzanol decreases cholesterol absorption and aortic fatty streaks in hamsters. Lipids. 1997;32:303-9.
32. Plat J, Mensink RP. Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women. FASEB J. 2002;16:258-60.
33. Rudling M. Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinated regulation in vivo. J Lipid Res. 1992;33:493-501.
34. Parillo M, Rivellese AA, Ciardullo AV, Capaldo B, Giacco A, Genovese S, Riccardi G. A high-monounsaturated-fat/low-carbohydrate diet improves peripheral insulin sensitivity in non-insulin-dependent diabetic patients. Metabolism. 1992;41:1373-8.
35. Ryysy L, Hakkinen AM, Goto T, Vehkavaara S, Westerbacka J, Jalavaara J, Yki-Jarvinen H. Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes. 2000;49:749-58.