A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 2, 2010, Pages 414-420

  Noh, Ji Yoon ^a   Park, Jong Sook ^a   Lim, Kyung Min ^a   Kim, Keunyoung ^a   Bae, Ok Nam ^a   Chung, Seung Min ^a   Shin, Sue ^b   Chung, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Boramae Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LAPACHONE; CARRIER PROTEIN; GLUTATHIONE; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PROTEIN; REACTIVE OXYGEN METABOLITE; SCRAMBLASE; THIOL;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD TOXICITY; CELL ISOLATION; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVITY; ERYTHROCYTE; ERYTHROCYTE DISORDER; ERYTHROPHAGOCYTOSIS; FACILITATION; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; SPLEEN;

ADENOSINE TRIPHOSPHATE; ADOLESCENT; ADULT; ANEMIA; ANIMALS; CALCIUM; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; FLOW CYTOMETRY; GLUTATHIONE; HEMOLYSIS; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; NAPHTHOQUINONES; OXIDATIVE STRESS; PHAGOCYTOSIS; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; YOUNG ADULT;

EID: 77951062025     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.164608     Document Type: Article

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