메뉴 건너뛰기




Volumn 70, Issue 6, 2010, Pages 733-759

Strontium Ranelate: A Review of its Use in the Treatment of Postmenopausal Osteoporosis

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; ALUMINUM HYDROXIDE; BISPHOSPHONIC ACID DERIVATIVE; BIVALOS; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; ETIDRONIC ACID; IBANDRONIC ACID; MAGNESIUM HYDROXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PLACEBO; PROTAXOS; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RALOXIFENE; RISEDRONIC ACID; STRONTIUM RANELATE; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG; VITAMIN D; ZOLEDRONIC ACID;

EID: 77951048379     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/10481900-000000000-00000     Document Type: Review
Times cited : (47)

References (104)
  • 2
    • 43449107330 scopus 로고    scopus 로고
    • National Osteoporosis Foundation [online] [Accessed 2009 Oct 23]
    • National Osteoporosis Foundation. Clinician's guide to prevention and treatment of osteoporosis [online]. Available from URL: http://www.nof.org/ professionals/NOF- Clinicians-Guide.pdf [Accessed 2009 Oct 23]
    • Clinician's Guide to Prevention and Treatment of Osteoporosis
  • 3
    • 38149108553 scopus 로고    scopus 로고
    • International Osteoporosis Foundation [online] [Accessed 2009 Oct 23]
    • International Osteoporosis Foundation. Facts and statistics about osteoporosis and its impact [online]. Available from URL: http://www. iofbonehealth.org/facts-and-sta tistics.html#factsheet-category-22 [Accessed 2009 Oct 23]
    • Facts and Statistics about Osteoporosis and Its Impact
  • 4
    • 33751229879 scopus 로고    scopus 로고
    • Anabolic agents for osteoporosis: What is their likely place in therapy?
    • Girotra M, Rubin MR, Bilezikian JP. Anabolic agents for osteoporosis: what is their likely place in therapy? Treat Endocrinol 2006; 5 (6): 347-358
    • (2006) Treat Endocrinol , vol.5 , Issue.6 , pp. 347-358
    • Girotra, M.1    Rubin, M.R.2    Bilezikian, J.P.3
  • 5
    • 0037319807 scopus 로고    scopus 로고
    • Strontium ranelate: A new paradigm in the treatment of osteoporosis
    • Feb
    • Reginster JY, Deroisy R, Jupsin I. Strontium ranelate: a new paradigm in the treatment of osteoporosis. Drugs Today (Barc) 2003 Feb; 39 (2): 89-101
    • (2003) Drugs Today (Barc) , vol.39 , Issue.2 , pp. 89-101
    • Reginster, J.Y.1    Deroisy, R.2    Jupsin, I.3
  • 6
    • 0034815044 scopus 로고    scopus 로고
    • Mechanisms of action and therapeutic potential of strontium in bone
    • Sep
    • Marie PJ, Ammann P, Boivin G, et al. Mechanisms of action and therapeutic potential of strontium in bone. Calcif Tissue Int 2001 Sep; 69 (3): 121-129
    • (2001) Calcif Tissue Int , vol.69 , Issue.3 , pp. 121-129
    • Marie, P.J.1    Ammann, P.2    Boivin, G.3
  • 7
    • 33747885671 scopus 로고    scopus 로고
    • Strontium ranelate: A dual mode of action rebalancing bone turnover in favour of bone formation
    • Jun
    • Marie PJ. Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol 2006 Jun; 18 Suppl. 1: S11-5
    • (2006) Curr Opin Rheumatol , vol.18 , Issue.SUPPL. 1
    • Marie, P.J.1
  • 8
    • 34147177628 scopus 로고    scopus 로고
    • Strontium ranelate: New insights into its dual mode of action
    • Marie PJ. Strontium ranelate: new insights into its dual mode of action. Bone 2007; 40 (5 Suppl. 1): S5-8
    • (2007) Bone , vol.40 , Issue.5 SUPPL. 1
    • Marie, P.J.1
  • 9
    • 45749103255 scopus 로고    scopus 로고
    • Rebalancing bone turnover in favour of formation with strontium ranelate: Implications for bone strength
    • Jul
    • Fonseca JE. Rebalancing bone turnover in favour of formation with strontium ranelate: implications for bone strength. Rheumatology (Oxford) 2008 Jul; 47 (Suppl. 4): iv17-9
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.SUPPL. 4
    • Fonseca, J.E.1
  • 10
    • 77951048322 scopus 로고    scopus 로고
    • European Medicines Agency [online] [Accessed 2009 Oct 20]
    • European Medicines Agency. Protelos 2g granules for oral suspension: summary of product characteristics [online]. Available from URL: http://www.emea.europa.eu/humandocs/PDFs/EPAR/protelos/emea-combined-h560en. pdf [Accessed 2009 Oct 20]
    • Protelos 2g Granules for Oral Suspension: Summary of Product Characteristics
  • 11
    • 77951059909 scopus 로고    scopus 로고
    • European Medicines Agency [online] [Accessed 2009 Oct 12]
    • European Medicines Agency. Protelos: scientific discussion [online]. Available from URL: http://www.emea.europa. eu/humandocs/PDFs/EPAR/protelos/ 121604en6.pdf [Accessed 2009 Oct 12]
    • Protelos: Scientific Discussion
  • 12
    • 0030176233 scopus 로고    scopus 로고
    • The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro
    • Jun
    • Canalis E, Hott M, Deloffre P, et al. The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro. Bone 1996 Jun; 18 (6): 517-523
    • (1996) Bone , vol.18 , Issue.6 , pp. 517-523
    • Canalis, E.1    Hott, M.2    Deloffre, P.3
  • 13
    • 37349123534 scopus 로고    scopus 로고
    • Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro
    • Jan
    • Bonnelye E, Chabadel A, Saltel F, et al. Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone 2008 Jan; 42 (1): 129-138
    • (2008) Bone , vol.42 , Issue.1 , pp. 129-138
    • Bonnelye, E.1    Chabadel, A.2    Saltel, F.3
  • 14
    • 62149087855 scopus 로고    scopus 로고
    • Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprote-gerin response
    • Apr
    • Atkins GJ, Welldon KJ, Halbout P, et al. Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprote-gerin response. Osteoporos Int 2009 Apr; 20 (4): 653-664
    • (2009) Osteoporos Int , vol.20 , Issue.4 , pp. 653-664
    • Atkins, G.J.1    Welldon, K.J.2    Halbout, P.3
  • 15
    • 0037118899 scopus 로고    scopus 로고
    • In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation
    • Aug 16
    • Baron R, Tsouderos Y. In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur J Pharmacol 2002 Aug 16; 450 (1): 11-17
    • (2002) Eur J Pharmacol , vol.450 , Issue.1 , pp. 11-17
    • Baron, R.1    Tsouderos, Y.2
  • 16
    • 0142122898 scopus 로고    scopus 로고
    • S 12911-2 inhibits osteoclastic bone resorption in vitro
    • Jun
    • Takahashi N, Sasaki T, Tsouderos Y, et al. S 12911-2 inhibits osteoclastic bone resorption in vitro. J Bone Miner Res 2003 Jun; 18 (6): 1082-1087
    • (2003) J Bone Miner Res , vol.18 , Issue.6 , pp. 1082-1087
    • Takahashi, N.1    Sasaki, T.2    Tsouderos, Y.3
  • 17
    • 0036068720 scopus 로고    scopus 로고
    • Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice
    • Jul
    • Delannoy P, Bazot D, Marie PJ. Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. Metabolism 2002 Jul; 51 (7): 906-911
    • (2002) Metabolism , vol.51 , Issue.7 , pp. 906-911
    • Delannoy, P.1    Bazot, D.2    Marie, P.J.3
  • 18
    • 0042707618 scopus 로고    scopus 로고
    • S12911-2 reduces bone loss induced by short-term immobilization in rats
    • Jul
    • Hott M, Deloffre P, Tsouderos Y, et al. S12911-2 reduces bone loss induced by short-term immobilization in rats. Bone 2003 Jul; 33 (1): 115-123
    • (2003) Bone , vol.33 , Issue.1 , pp. 115-123
    • Hott, M.1    Deloffre, P.2    Tsouderos, Y.3
  • 19
    • 0034902167 scopus 로고    scopus 로고
    • Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis)
    • Aug
    • Buehler J, Chappuis P, Saffar JL, et al. Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis). Bone 2001 Aug; 29 (2): 176-179
    • (2001) Bone , vol.29 , Issue.2 , pp. 176-179
    • Buehler, J.1    Chappuis, P.2    Saffar, J.L.3
  • 20
    • 0027316220 scopus 로고
    • An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats
    • May
    • Marie PJ, Hott M, Modrowski D, et al. An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993 May; 8 (5): 607-615
    • (1993) J Bone Miner Res , vol.8 , Issue.5 , pp. 607-615
    • Marie, P.J.1    Hott, M.2    Modrowski, D.3
  • 21
    • 70350304534 scopus 로고    scopus 로고
    • Osteoblasts play key roles in the mechanisms of action of strontium ranelate
    • Aug
    • Brennan TC, Rybchyn MS, Green W, et al. Osteoblasts play key roles in the mechanisms of action of strontium ranelate. Br J Pharmacol 2009 Aug; 157 (7): 1291-1300
    • (2009) Br J Pharmacol , vol.157 , Issue.7 , pp. 1291-1300
    • Brennan, T.C.1    Rybchyn, M.S.2    Green, W.3
  • 22
    • 4644294488 scopus 로고    scopus 로고
    • In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor
    • Oct 29
    • Coulombe J, Faure H, Robin B, et al. In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor. Biochem Biophys Res Commun 2004 Oct 29; 323 (4): 1184-1190
    • (2004) Biochem Biophys Res Commun , vol.323 , Issue.4 , pp. 1184-1190
    • Coulombe, J.1    Faure, H.2    Robin, B.3
  • 23
    • 34250870142 scopus 로고    scopus 로고
    • The calciumsensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation
    • Aug 1
    • Chattopadhyay N, Quinn SJ, Kifor O, et al. The calciumsensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation. Biochem Pharmacol 2007 Aug 1; 74 (3): 438-447
    • (2007) Biochem Pharmacol , vol.74 , Issue.3 , pp. 438-447
    • Chattopadhyay, N.1    Quinn, S.J.2    Kifor, O.3
  • 24
    • 33847162089 scopus 로고    scopus 로고
    • Induction of a program gene expression during osteoblast differentiation with strontium ranelate
    • Apr 6
    • Zhu LL, Zaidi S, Peng Y, et al. Induction of a program gene expression during osteoblast differentiation with strontium ranelate. Biochem Biophys Res Commun 2007 Apr 6; 355 (2): 307-311
    • (2007) Biochem Biophys Res Commun , vol.355 , Issue.2 , pp. 307-311
    • Zhu, L.L.1    Zaidi, S.2    Peng, Y.3
  • 25
    • 43149125403 scopus 로고    scopus 로고
    • Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms
    • Jun
    • Caverzasio J. Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms. Bone 2008 Jun; 42 (6): 1131-1136
    • (2008) Bone , vol.42 , Issue.6 , pp. 1131-1136
    • Caverzasio, J.1
  • 26
    • 58649120832 scopus 로고    scopus 로고
    • The calcium-sensing receptor is involved in strontium rane-late-induced osteoclast apoptosis: New insights into the associated signaling pathways
    • Jan 2
    • Hurtel-Lemaire AS, Mentaverri R, Caudrillier A, et al. The calcium-sensing receptor is involved in strontium rane-late-induced osteoclast apoptosis: new insights into the associated signaling pathways. J Biol Chem 2009 Jan 2; 284 (1): 575-584
    • (2009) J Biol Chem , vol.284 , Issue.1 , pp. 575-584
    • Hurtel-Lemaire, A.S.1    Mentaverri, R.2    Caudrillier, A.3
  • 27
    • 72949086648 scopus 로고    scopus 로고
    • Calcium sensing receptor-dependent and-independent activation of osteo-blast replication and survival by strontium ranelate
    • Epub 2009 Jan 28
    • Fromigue O, Hay E, Barbara A, et al. Calcium sensing receptor-dependent and-independent activation of osteo-blast replication and survival by strontium ranelate. J Cell Mol Med. Epub 2009 Jan 28
    • J Cell Mol Med
    • Fromigue, O.1    Hay, E.2    Barbara, A.3
  • 28
    • 17644382533 scopus 로고    scopus 로고
    • Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats
    • Dec
    • Ammann P, Shen V, Robin B, et al. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. J Bone Miner Res 2004 Dec; 19 (12): 2012-2020
    • (2004) J Bone Miner Res , vol.19 , Issue.12 , pp. 2012-2020
    • Ammann, P.1    Shen, V.2    Robin, B.3
  • 29
    • 36049018715 scopus 로고    scopus 로고
    • Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength
    • Sep
    • Ammann P, Badoud I, Barraud S, et al. Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength. J Bone Miner Res 2007 Sep; 22 (9): 1419-1425
    • (2007) J Bone Miner Res , vol.22 , Issue.9 , pp. 1419-1425
    • Ammann, P.1    Badoud, I.2    Barraud, S.3
  • 30
    • 67650476919 scopus 로고    scopus 로고
    • Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants
    • Aug
    • Bain SD, Jerome C, Shen V, et al. Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants. Osteoporos Int 2009 Aug; 20 (8): 1417-1428
    • (2009) Osteoporos Int , vol.20 , Issue.8 , pp. 1417-1428
    • Bain, S.D.1    Jerome, C.2    Shen, V.3
  • 31
    • 38549175745 scopus 로고    scopus 로고
    • Histomorphometric and mCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate
    • Feb
    • Arlot ME, Jiang Y, Genant HK, et al. Histomorphometric and mCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate. J Bone Miner Res 2008 Feb; 23 (2): 215-222
    • (2008) J Bone Miner Res , vol.23 , Issue.2 , pp. 215-222
    • Arlot, M.E.1    Jiang, Y.2    Genant, H.K.3
  • 32
    • 18344379873 scopus 로고    scopus 로고
    • Strontium ranelate: Dose-dependent effects in established postmen-opausal vertebral osteoporosis-a 2-year randomized placebo controlled trial
    • May
    • Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmen-opausal vertebral osteoporosis-a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002 May; 87 (5): 2060-2066
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.5 , pp. 2060-2066
    • Meunier, P.J.1    Slosman, D.O.2    Delmas, P.D.3
  • 34
    • 21044447888 scopus 로고    scopus 로고
    • Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: TReatment of Peripheral OSteoporosis (TROPOS) study
    • May
    • Reginster JY, Seeman E, De Vernejoul MC, et al. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: TReatment Of Peripheral OSteoporosis (TROPOS) study. J Clin En-docrinol Metab 2005 May; 90 (5): 2816-2822
    • (2005) J Clin En-docrinol Metab , vol.90 , Issue.5 , pp. 2816-2822
    • Reginster, J.Y.1    Seeman, E.2    De Vernejoul, M.C.3
  • 35
    • 68949100644 scopus 로고    scopus 로고
    • Comparative effects of teriparatide and strontium ranelate on bone biopsies and biochemical markers of bone turnover in postmenopausal women with osteoporosis
    • Aug
    • Recker RR, Marin F, Ish-Shalom S, et al. Comparative effects of teriparatide and strontium ranelate on bone biopsies and biochemical markers of bone turnover in postmenopausal women with osteoporosis. J Bone Miner Res 2009 Aug; 24 (8): 1358-1368
    • (2009) J Bone Miner Res , vol.24 , Issue.8 , pp. 1358-1368
    • Recker, R.R.1    Marin, F.2    Ish-Shalom, S.3
  • 36
    • 70149117614 scopus 로고    scopus 로고
    • Effect of strontium ranelate on lumbar spine bone mineral density in women with established osteoporosis previously treated with teriparatide
    • Jul
    • Anastasilakis AD, Polyzos SA, Avramidis A, et al. Effect of strontium ranelate on lumbar spine bone mineral density in women with established osteoporosis previously treated with teriparatide. Horm Metab Res 2009 Jul; 41 (7): 559-562
    • (2009) Horm Metab Res , vol.41 , Issue.7 , pp. 559-562
    • Anastasilakis, A.D.1    Polyzos, S.A.2    Avramidis, A.3
  • 37
    • 77951049321 scopus 로고    scopus 로고
    • The effect of prior bisphosphonate therapy on the subsequent BMD and bone turnover response to strontium ranelate
    • Dec 11
    • Middleton ET, Steel SA, Aye M, et al. The effect of prior bisphosphonate therapy on the subsequent BMD and bone turnover response to strontium ranelate. J Bone Miner Res 2009 Dec 11; 25 (3): 455-462
    • (2009) J Bone Miner Res , vol.25 , Issue.3 , pp. 455-462
    • Middleton, E.T.1    Steel, S.A.2    Aye, M.3
  • 38
    • 78149408954 scopus 로고    scopus 로고
    • Systemic treatment with strontium ranelate promotes tibial fracture healing in ovariectomized rats
    • Epub 2009 Dec
    • Li YF, Luo E, Feng G, et al. Systemic treatment with strontium ranelate promotes tibial fracture healing in ovariectomized rats. Osteoporos Int. Epub 2009 Dec
    • Osteoporos Int
    • Li, Y.F.1    Luo, E.2    Feng, G.3
  • 39
    • 73649136450 scopus 로고    scopus 로고
    • Strontium ranelate enhances callus strength more than PTH 1-34 in an osteoporotic rat model of fracture healing
    • Jan
    • Habermann B, Kafchitsas K, Olender G, et al. Strontium ranelate enhances callus strength more than PTH 1-34 in an osteoporotic rat model of fracture healing. Calcif Tissue Int 2010 Jan; 86 (1): 82-89
    • (2010) Calcif Tissue Int , vol.86 , Issue.1 , pp. 82-89
    • Habermann, B.1    Kafchitsas, K.2    Olender, G.3
  • 40
    • 24144474976 scopus 로고    scopus 로고
    • Long-term strontium ranelate administration in monkeys preserves characteristics of bone mineral crystals and degree of mineralization of bone
    • Sep
    • Farlay D, Boivin G, Panczer G, et al. Long-term strontium ranelate administration in monkeys preserves characteristics of bone mineral crystals and degree of mineralization of bone. J Bone Miner Res 2005 Sep; 20 (9): 1569-1578
    • (2005) J Bone Miner Res , vol.20 , Issue.9 , pp. 1569-1578
    • Farlay, D.1    Boivin, G.2    Panczer, G.3
  • 41
    • 77950940515 scopus 로고    scopus 로고
    • In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization
    • Apr
    • Boivin G, Farlay D, Khebbab MT, et al. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Osteoporos Int 2010 Apr; 21 (4): 667-677
    • Osteoporos Int 2010 , vol.21 , Issue.4 , pp. 667-677
    • Boivin, G.1    Farlay, D.2    Khebbab, M.T.3
  • 42
    • 69949149543 scopus 로고    scopus 로고
    • Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis
    • Oct
    • Meunier PJ, Roux C, Ortolani S, et al. Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis. Osteoporos Int 2009 Oct; 20 (10): 1663-1673
    • (2009) Osteoporos Int , vol.20 , Issue.10 , pp. 1663-1673
    • Meunier, P.J.1    Roux, C.2    Ortolani, S.3
  • 43
    • 58549102898 scopus 로고    scopus 로고
    • The effects of strontium ranelate in Asian women with postmenopausal osteoporosis [published erratum appears in Calcif Tissue Int 2009 Apr; 84 (4): 334]
    • Nov
    • Hwang JS, Chen JF, Yang TS, et al. The effects of strontium ranelate in Asian women with postmenopausal osteoporosis [published erratum appears in Calcif Tissue Int 2009 Apr; 84 (4): 334]. Calcif Tissue Int 2008 Nov; 83 (5): 308-314
    • (2008) Calcif Tissue Int , vol.83 , Issue.5 , pp. 308-314
    • Hwang, J.S.1    Chen, J.F.2    Yang, T.S.3
  • 44
    • 33845191832 scopus 로고    scopus 로고
    • Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women
    • Jan
    • Alexandersen P, Karsdal MA, Qvist P, et al. Strontium ranelate reduces the urinary level of cartilage degradation biomarker CTX-II in postmenopausal women. Bone 2007 Jan; 40 (1): 218-222
    • (2007) Bone , vol.40 , Issue.1 , pp. 218-222
    • Alexandersen, P.1    Karsdal, M.A.2    Qvist, P.3
  • 45
    • 61449099574 scopus 로고    scopus 로고
    • No difference between strontium ranelate (SR) and calcium/vitamin D on bone turnover markers in women with established osteoporosis previously treated with teripara-tide: A randomized controlled trial
    • Apr
    • Anastasilakis AD, Goulis DG, Polyzos SA, et al. No difference between strontium ranelate (SR) and calcium/vitamin D on bone turnover markers in women with established osteoporosis previously treated with teripara-tide: a randomized controlled trial. Clin Endocrinol (Oxf) 2009 Apr; 70 (4): 522-526
    • (2009) Clin Endocrinol (Oxf) , vol.70 , Issue.4 , pp. 522-526
    • Anastasilakis, A.D.1    Goulis, D.G.2    Polyzos, S.A.3
  • 46
    • 77954565409 scopus 로고    scopus 로고
    • Relationship between 3-month changes in biochemical markers of bone remodelling and changes in bone mineral density and fracture incidence in patients treated with strontium ra-nelate for 3 years
    • Epub 2009 Oct
    • Bruyere O, Collette J, Rizzoli R, et al. Relationship between 3-month changes in biochemical markers of bone remodelling and changes in bone mineral density and fracture incidence in patients treated with strontium ra-nelate for 3 years. Osteoporos Int. Epub 2009 Oct
    • Osteoporos Int
    • Bruyere, O.1    Collette, J.2    Rizzoli, R.3
  • 47
    • 33846419499 scopus 로고    scopus 로고
    • Short-term hemostatic safety of strontium ranelate treatment in elderly women with osteoporosis
    • Jan
    • Halil M, Cankurtaran M, Yavuz BB, et al. Short-term hemostatic safety of strontium ranelate treatment in elderly women with osteoporosis. Ann Pharmacother 2007 Jan; 41 (1): 41-45
    • (2007) Ann Pharmacother , vol.41 , Issue.1 , pp. 41-45
    • Halil, M.1    Cankurtaran, M.2    Yavuz, B.B.3
  • 48
    • 70350214648 scopus 로고    scopus 로고
    • Long-term treatment of postmenopausal osteoporosis with strontium ranelate: Results at 8 years
    • Dec
    • Reginster JY, Bruyere O, Sawicki A, et al. Long-term treatment of postmenopausal osteoporosis with strontium ranelate: results at 8 years. Bone 2009 Dec; 45 (6): 1059-1064
    • (2009) Bone , vol.45 , Issue.6 , pp. 1059-1064
    • Reginster, J.Y.1    Bruyere, O.2    Sawicki, A.3
  • 49
    • 68049144652 scopus 로고    scopus 로고
    • Efficacy and safety of 2g/day of strontium ranelate in Asian women with postmenopausal osteoporosis
    • Sep
    • Liu JM, Wai-Chee Kung A, Pheng CS, et al. Efficacy and safety of 2g/day of strontium ranelate in Asian women with postmenopausal osteoporosis. Bone 2009 Sep; 45 (3): 460-465
    • (2009) Bone , vol.45 , Issue.3 , pp. 460-465
    • Liu, J.M.1    Wai-Chee Kung, A.2    Pheng, C.S.3
  • 50
    • 77955094693 scopus 로고    scopus 로고
    • Absolute risk reduction in osteoporosis: Assessing treatment efficacy by number needed to treat
    • Epub 2009 Dec
    • Ringe JD, Doherty JG. Absolute risk reduction in osteoporosis: assessing treatment efficacy by number needed to treat. Rheumatol Int. Epub 2009 Dec
    • Rheumatol Int
    • Ringe, J.D.1    Doherty, J.G.2
  • 51
    • 45349090543 scopus 로고    scopus 로고
    • Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial
    • Jun
    • Reginster JY, Felsenberg D, Boonen S, et al. Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: results of a five-year, randomized, placebo-controlled trial. Arthritis Rheum 2008 Jun; 58 (6): 1687-1695
    • (2008) Arthritis Rheum , vol.58 , Issue.6 , pp. 1687-1695
    • Reginster, J.Y.1    Felsenberg, D.2    Boonen, S.3
  • 52
    • 47249093704 scopus 로고    scopus 로고
    • Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis
    • Apr
    • Marquis P, Roux C, de la Loge C, et al. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. Osteo-poros Int 2008 Apr; 19 (4): 503-510
    • (2008) Osteo-poros Int , vol.19 , Issue.4 , pp. 503-510
    • Marquis, P.1    Roux, C.2    De La Loge, C.3
  • 53
    • 34547790885 scopus 로고    scopus 로고
    • Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate
    • Aug
    • Bruyere O, Roux C, Detilleux J, et al. Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. J Clin Endocrinol Metab 2007 Aug; 92 (8): 3076-3081
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.8 , pp. 3076-3081
    • Bruyere, O.1    Roux, C.2    Detilleux, J.3
  • 54
    • 37749000351 scopus 로고    scopus 로고
    • Relationship between change in femoral neck bone mineral density and hip fracture incidence during treatment with strontium rane-late
    • Dec
    • Bruyere O, Roux C, Badurski J, et al. Relationship between change in femoral neck bone mineral density and hip fracture incidence during treatment with strontium rane-late. Curr Med Res Opin 2007 Dec; 23 (12): 3041-3045
    • (2007) Curr Med Res Opin , vol.23 , Issue.12 , pp. 3041-3045
    • Bruyere, O.1    Roux, C.2    Badurski, J.3
  • 55
    • 33645353336 scopus 로고    scopus 로고
    • Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors
    • Apr
    • Roux C, Reginster JY, Fechtenbaum J, et al. Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors. J Bone Miner Res 2006 Apr; 21 (4): 536-542
    • (2006) J Bone Miner Res , vol.21 , Issue.4 , pp. 536-542
    • Roux, C.1    Reginster, J.Y.2    Fechtenbaum, J.3
  • 56
    • 76549099332 scopus 로고    scopus 로고
    • Vertebral antifracture efficacy of strontium ranelate according to pre-treatment bone turnover
    • Feb
    • Collette J, Bruyere O, Kaufman JM, et al. Vertebral antifracture efficacy of strontium ranelate according to pre-treatment bone turnover. Osteoporos Int 2010 Feb; 21 (2): 233-241
    • (2010) Osteoporos Int , vol.21 , Issue.2 , pp. 233-241
    • Collette, J.1    Bruyere, O.2    Kaufman, J.M.3
  • 57
    • 33745494818 scopus 로고    scopus 로고
    • Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older
    • Jul
    • Seeman E, Vellas B, Benhamou C, et al. Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older. J Bone Miner Res 2006 Jul; 21 (7): 1113-1120
    • (2006) J Bone Miner Res , vol.21 , Issue.7 , pp. 1113-1120
    • Seeman, E.1    Vellas, B.2    Benhamou, C.3
  • 58
    • 77950546166 scopus 로고    scopus 로고
    • Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age
    • Apr
    • Seeman E, Boonen S, Borgstrom F, et al. Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. Bone 2010 Apr; 46 (4): 1038-1042
    • (2010) Bone , vol.46 , Issue.4 , pp. 1038-1042
    • Seeman, E.1    Boonen, S.2    Borgstrom, F.3
  • 59
    • 56749180405 scopus 로고    scopus 로고
    • Strontium ranelate reduces the risk of vertebral fracture in young postmeno-pausal women with severe osteoporosis
    • Dec
    • Roux C, Fechtenbaum J, Kolta S, et al. Strontium ranelate reduces the risk of vertebral fracture in young postmeno-pausal women with severe osteoporosis. Ann Rheum Dis 2008 Dec; 67 (12): 1736-1738
    • (2008) Ann Rheum Dis , vol.67 , Issue.12 , pp. 1736-1738
    • Roux, C.1    Fechtenbaum, J.2    Kolta, S.3
  • 60
    • 39549083894 scopus 로고    scopus 로고
    • Effects of strontium ranelate on spinal osteoarthritis progression
    • Mar
    • Bruyere O, Delferriere D, Roux C, et al. Effects of strontium ranelate on spinal osteoarthritis progression. Ann Rheum Dis 2008 Mar; 67 (3): 335-339
    • (2008) Ann Rheum Dis , vol.67 , Issue.3 , pp. 335-339
    • Bruyere, O.1    Delferriere, D.2    Roux, C.3
  • 61
    • 77953372030 scopus 로고    scopus 로고
    • Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis
    • Epub 2009 Jul 13
    • Roux C, Fechtenbaum J, Kolta S, et al. Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis. J Bone Miner Res. Epub 2009 Jul 13
    • J Bone Miner Res
    • Roux, C.1    Fechtenbaum, J.2    Kolta, S.3
  • 62
    • 39749127750 scopus 로고    scopus 로고
    • Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia
    • Mar
    • Seeman E, Devogelaer JP, Lorenc R, et al. Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia. J Bone Miner Res 2008 Mar; 23 (3): 433-438
    • (2008) J Bone Miner Res , vol.23 , Issue.3 , pp. 433-438
    • Seeman, E.1    Devogelaer, J.P.2    Lorenc, R.3
  • 63
    • 55149085956 scopus 로고    scopus 로고
    • Post-marketing assessment of the safety of strontium ranelate; A novel case-only approach to the early detection of adverse drug reactions
    • Nov
    • Grosso A, Douglas I, Hingorani A, et al. Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. Br J Clin Pharmacol 2008 Nov; 66 (5): 689-694
    • (2008) Br J Clin Pharmacol , vol.66 , Issue.5 , pp. 689-694
    • Grosso, A.1    Douglas, I.2    Hingorani, A.3
  • 64
    • 78149459093 scopus 로고    scopus 로고
    • Osteoporosis and venous thromboembolism: A retrospective cohort study in the UK and General Practice Research Database
    • Epub 2009 Oct 6
    • Breart G, Cooper C, Meyer O, et al. Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK and General Practice Research Database. Osteo-poros Int. Epub 2009 Oct 6
    • Osteo-poros Int
    • Breart, G.1    Cooper, C.2    Meyer, O.3
  • 65
    • 33750204879 scopus 로고    scopus 로고
    • An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials
    • Dec
    • Borgstrom F, Jonsson B, Strom O, et al. An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: based on the results of the SOTI and TROPOS trials. Osteoporos Int 2006 Dec; 17 (12): 1781-1793
    • (2006) Osteoporos Int , vol.17 , Issue.12 , pp. 1781-1793
    • Borgstrom, F.1    Jonsson, B.2    Strom, O.3
  • 66
    • 76549094180 scopus 로고    scopus 로고
    • The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis
    • Feb
    • Borgstrom F, Strom O, Coelho J, et al. The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis. Osteoporos Int 2010 Feb; 21 (2): 339-349
    • (2010) Osteoporos Int , vol.21 , Issue.2 , pp. 339-349
    • Borgstrom, F.1    Strom, O.2    Coelho, J.3
  • 67
    • 72449152953 scopus 로고    scopus 로고
    • Cost-utility of long-term strontium ranelate treatment for postmeno-pausal osteoporotic women
    • Jan
    • Hiligsmann M, Bruyere O, Reginster JY. Cost-utility of long-term strontium ranelate treatment for postmeno-pausal osteoporotic women. Osteoporos Int 2010 Jan; 21 (1): 157-165
    • (2010) Osteoporos Int , vol.21 , Issue.1 , pp. 157-165
    • Hiligsmann, M.1    Bruyere, O.2    Reginster, J.Y.3
  • 68
    • 74249083881 scopus 로고    scopus 로고
    • Cost-effectiveness of strontium ranelate versus risedronate in the treatment of postmenopausal osteoporotic women aged over 75 years
    • Feb
    • Hiligsmann M, Bruyere O, Reginster JY. Cost-effectiveness of strontium ranelate versus risedronate in the treatment of postmenopausal osteoporotic women aged over 75 years. Bone 2010 Feb; 46 (2): 440-446
    • (2010) Bone , vol.46 , Issue.2 , pp. 440-446
    • Hiligsmann, M.1    Bruyere, O.2    Reginster, J.Y.3
  • 69
  • 70
    • 44949191491 scopus 로고    scopus 로고
    • Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    • Wells G, Cranney A, Peterson J, et al. Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. Cochrane Database Syst Rev [CD004523]
    • Cochrane Database Syst Rev
    • Wells, G.1    Cranney, A.2    Peterson, J.3
  • 72
    • 44649120398 scopus 로고    scopus 로고
    • European guidance for the diagnosis and management of osteoporosis in postmenopausal women [published erratum appears in Osteoporos Int 2008 Jul; 19 (7): 1103-4]
    • Apr
    • Kanis JA, Burlet N, Cooper C, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women [published erratum appears in Osteoporos Int 2008 Jul; 19 (7): 1103-4]. Osteoporos Int 2008 Apr; 19 (4): 399-428
    • (2008) Osteoporos Int , vol.19 , Issue.4 , pp. 399-428
    • Kanis, J.A.1    Burlet, N.2    Cooper, C.3
  • 73
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesisof osteoporosis: Concepts, conflicts, and prospects
    • Dec
    • Raisz LG. Pathogenesisof osteoporosis: concepts, conflicts, and prospects. J Clin Invest 2005 Dec; 115 (12): 3318-3325
    • (2005) J Clin Invest , vol.115 , Issue.12 , pp. 3318-3325
    • Raisz, L.G.1
  • 74
    • 54549121554 scopus 로고    scopus 로고
    • Zoledronic acid: A review of its use in the treatment of osteoporosis
    • Deeks ED, Perry CM. Zoledronic acid: a review of its use in the treatment of osteoporosis. Drugs Aging 2008; 25 (11): 963-986
    • (2008) Drugs Aging , vol.25 , Issue.11 , pp. 963-986
    • Deeks, E.D.1    Perry, C.M.2
  • 76
    • 19544376123 scopus 로고    scopus 로고
    • Optimizing the management of postmenopausal osteoporosis with bisphosphonates: The emerging role of intermittent therapy
    • Apr
    • Miller PD. Optimizing the management of postmenopausal osteoporosis with bisphosphonates: the emerging role of intermittent therapy. Clin Ther 2005 Apr; 27 (4): 361-376
    • (2005) Clin Ther , vol.27 , Issue.4 , pp. 361-376
    • Miller, P.D.1
  • 83
    • 33745069049 scopus 로고    scopus 로고
    • How can osteoporosis patients benefit more from their therapy? Adherence issues with bisphosphonate therapy
    • Jun
    • Gold DT, Alexander IM, Ettinger MP. How can osteoporosis patients benefit more from their therapy? Adherence issues with bisphosphonate therapy. Ann Pharmacother 2006 Jun; 40 (6): 1143-1150
    • (2006) Ann Pharmacother , vol.40 , Issue.6 , pp. 1143-1150
    • Gold, D.T.1    Alexander, I.M.2    Ettinger, M.P.3
  • 85
    • 44949104622 scopus 로고    scopus 로고
    • Procter and Gamble Pharmaceuticals UK Limited [online] [Accessed 2010 Mar 24]
    • Procter and Gamble Pharmaceuticals UK Limited. Actonel 5mg film coated tablets: summary of product characteristics [online]. Available from URL: http://emc. medicines.org.uk [Accessed 2010 Mar 24]
    • Actonel 5mg Film Coated Tablets: Summary of Product Characteristics
  • 86
    • 15044360901 scopus 로고    scopus 로고
    • Evidence-based guidelines for the treatment of postmenopausal osteoporosis: A consensus document of the Belgian Bone Club
    • Mar
    • Boonen S, Body JJ, Boutsen Y, et al. Evidence-based guidelines for the treatment of postmenopausal osteoporosis: a consensus document of the Belgian Bone Club. Osteoporos Int 2005 Mar; 16 (3) 239-254
    • (2005) Osteoporos Int , vol.16 , Issue.3 , pp. 239-254
    • Boonen, S.1    Body, J.J.2    Boutsen, Y.3
  • 87
    • 77951037807 scopus 로고    scopus 로고
    • Agence française de securite sanitaire des produits de sante [online] [Accessed 2010 Jan 19]
    • Agence française de securite sanitaire des produits de sante. Traitement medicamenteux de l'osteoporose post-meno-pausique: recommandations (actualisation 2006) [online]. Available from URL: http://www.afssaps.fr/var/ afssaps- site/storage/original/application/6c7b18b541509aa9f4994 84099d5f8e8.pdf [Accessed 2010 Jan 19]
    • Traitement Medicamenteux de l'Osteoporose Post-meno-pausique: Recommandations (Actualisation 2006)
  • 88
    • 63749127955 scopus 로고    scopus 로고
    • Clinical practice guidelines for postmenopausal, esteroid and male osteoporosis: Spanish Society for Bone and Mineral Research
    • May
    • Macas JG, Gay NG, Alonso CG, et al. Clinical practice guidelines for postmenopausal, esteroid and male osteoporosis: Spanish Society for Bone and Mineral Research. Rev Clin Esp 2008 May; 208 Suppl. 1, 1-24
    • (2008) Rev Clin Esp , vol.208 , Issue.SUPPL. 1 , pp. 1-24
    • MacAs, J.G.1    Gay, N.G.2    Alonso, C.G.3
  • 91
    • 70349335692 scopus 로고    scopus 로고
    • Management of osteoporosis in the elderly
    • Oct
    • Rizzoli R, Bruyere O, Cannata-Andia JB, et al. Management of osteoporosis in the elderly. Curr Med Res Opin 2009 Oct; 25 (10) 2373-2387
    • (2009) Curr Med Res Opin , vol.25 , Issue.10 , pp. 2373-2387
    • Rizzoli, R.1    Bruyere, O.2    Cannata-Andia, J.B.3
  • 92
    • 33846449098 scopus 로고    scopus 로고
    • Patient adherence to osteoporosis medications: Problems, consequences and management strategies
    • Papaioannou A, Kennedy CC, Dolovich L, et al. Patient adherence to osteoporosis medications: problems, consequences and management strategies. Drugs Aging 2007; 24 (1): 37-55
    • (2007) Drugs Aging , vol.24 , Issue.1 , pp. 37-55
    • Papaioannou, A.1    Kennedy, C.C.2    Dolovich, L.3
  • 93
    • 44949086638 scopus 로고    scopus 로고
    • Update on the treatment of post-menopausal osteoporosis
    • Cole Z, Dennison E, Cooper C. Update on the treatment of post-menopausal osteoporosis. Br Med Bull 2008; 86: 129-143
    • (2008) Br Med Bull , vol.86 , pp. 129-143
    • Cole, Z.1    Dennison, E.2    Cooper, C.3
  • 94
    • 56349136384 scopus 로고    scopus 로고
    • Osteoporosis and osteoporotic fracture occurrence and prevention in the elderly: A geriatric perspective
    • Oct
    • Boonen S, Dejaeger E, Vanderschueren D, et al. Osteoporosis and osteoporotic fracture occurrence and prevention in the elderly: a geriatric perspective. Best Pract Res Clin Endocrinol Metab 2008 Oct; 22 (5): 765-785
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , Issue.5 , pp. 765-785
    • Boonen, S.1    Dejaeger, E.2    Vanderschueren, D.3
  • 95
    • 63449117928 scopus 로고    scopus 로고
    • Efficacy and safety of pharmacological agents in managing osteoporosis in the old old: Review of the evidence
    • May
    • Inderjeeth CA, Foo ACH, Lai MMY, et al. Efficacy and safety of pharmacological agents in managing osteoporosis in the old old: review of the evidence. Bone 2009 May; 44 (5): 744-751
    • (2009) Bone , vol.44 , Issue.5 , pp. 744-751
    • Inderjeeth, C.A.1    Foo, A.C.H.2    Lai, M.M.Y.3
  • 96
    • 67349173181 scopus 로고    scopus 로고
    • Monitoring strontium ranelate therapy in patients with osteoporosis
    • Jul
    • Kendler DL, Adachi JD, Josse RG, et al. Monitoring strontium ranelate therapy in patients with osteoporosis. Osteoporos Int 2009 Jul; 20 (7): 1101-1106
    • (2009) Osteoporos Int , vol.20 , Issue.7 , pp. 1101-1106
    • Kendler, D.L.1    Adachi, J.D.2    Josse, R.G.3
  • 97
    • 67649443049 scopus 로고    scopus 로고
    • Effect of long-term treatment with strontium ranelate on bone strontium content
    • Aug
    • Barenholdt O, Kolthoff N, Nielsen SP. Effect of long-term treatment with strontium ranelate on bone strontium content. Bone 2009 Aug; 45 (2): 200-206
    • (2009) Bone , vol.45 , Issue.2 , pp. 200-206
    • Barenholdt, O.1    Kolthoff, N.2    Nielsen, S.P.3
  • 98
    • 67649331971 scopus 로고    scopus 로고
    • Raloxifene use in clinical practice: Efficacy and safety
    • Mar-Apr
    • Goldstein SR, Duvernoy CS, Calaf J, et al. Raloxifene use in clinical practice: efficacy and safety. Menopause 2009 Mar-Apr; 16 (2): 413-421
    • (2009) Menopause , vol.16 , Issue.2 , pp. 413-421
    • Goldstein, S.R.1    Duvernoy, C.S.2    Calaf, J.3
  • 99
    • 77951075374 scopus 로고    scopus 로고
    • Treatment of osteoporosis: Recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity
    • May
    • Musette P, Brandi ML, Cacoub P, et al. Treatment of osteoporosis: recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity. Os-teoporos Int 2010 May; 21 (5): 723-732
    • (2010) Os-teoporos Int , vol.21 , Issue.5 , pp. 723-732
    • Musette, P.1    Brandi, M.L.2    Cacoub, P.3
  • 101
    • 0035149060 scopus 로고    scopus 로고
    • The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis
    • Nov
    • Silverman SL, Minshall ME, Shen W, et al. The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis. Arthritis Rheum 2001 Nov; 44 (11): 2611-2619
    • (2001) Arthritis Rheum , vol.44 , Issue.11 , pp. 2611-2619
    • Silverman, S.L.1    Minshall, M.E.2    Shen, W.3
  • 102
    • 67149101339 scopus 로고    scopus 로고
    • Adherence to osteoporosis treatments: Room for improvement
    • Jul
    • Warriner AH, Curtis JR. Adherence to osteoporosis treatments: room for improvement. Curr Opin Rheuma-tol 2009 Jul; 21 (4): 356-362
    • (2009) Curr Opin Rheuma-tol , vol.21 , Issue.4 , pp. 356-362
    • Warriner, A.H.1    Curtis, J.R.2
  • 103
    • 78549267137 scopus 로고    scopus 로고
    • Positive impact of compliance to strontium ranelate on the risk of nonvertebral osteo-porotic fractures
    • Jan
    • Rabenda V, Reginster JY. Positive impact of compliance to strontium ranelate on the risk of nonvertebral osteo-porotic fractures. Osteoporos Int. Epub 2010 Jan
    • (2010) Osteoporos Int. Epub
    • Rabenda, V.1    Reginster, J.Y.2
  • 104
    • 33847356144 scopus 로고    scopus 로고
    • An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults
    • Feb
    • Richards JB, Cherkas LF, Spector TD. An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults. Curr Med Res Opin 2007 Feb; 23 (2): 293-9
    • (2007) Curr Med Res Opin , vol.23 , Issue.2 , pp. 293-9
    • Richards, J.B.1    Cherkas, L.F.2    Spector, T.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.