Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants

Osteoporosis International

Volumn 20, Issue 8, 2009, Pages 1417-1428

  Bain, S D ^a   Jerome, C ^b   Shen, V ^c   Dupin Roger, I ^d   Ammann, P ^e  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Think Bone Consulting Inc   (United States)

^c MDS Inc   (Canada)

^d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^e WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Bone biomechanics; Bone intrinsic quality; Bone micro architecture; Ovariectomized rat; Strontium ranelate

Indexed keywords

STRONTIUM RANELATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE MASS; BONE STRENGTH; BONE TURNOVER; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FRACTURE; IMAGING SYSTEM; LOADING TEST; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOPOROSIS; OVARIECTOMY; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING; VERTEBRA BODY; VERTEBRA FRACTURE;

ALKALINE PHOSPHATASE; AMINO ACIDS; ANIMALS; BONE DENSITY CONSERVATION AGENTS; BONE REMODELING; COMPRESSIVE STRENGTH; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; LUMBAR VERTEBRAE; ORGANOMETALLIC COMPOUNDS; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; STRONTIUM; THIOPHENES; X-RAY MICROTOMOGRAPHY;

EID: 67650476919     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-008-0815-8     Document Type: Article

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