메뉴 건너뛰기




Volumn 57, Issue 2, 2010, Pages 433-457

Immunosuppression Armamentarium in 2010: Mechanistic and Clinical Considerations

Author keywords

Immunosuppressive treatment; Induction; Maintenance immunosuppression; Mechanism of action; Pediatric transplantation; Side effects; Solid organ transplantation

Indexed keywords

ABATACEPT; ALEMTUZUMAB; AZATHIOPRINE; BASILIXIMAB; BELATACEPT; CALCINEURIN INHIBITOR; CYCLOSPORIN; DACLIZUMAB; EVEROLIMUS; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2 RECEPTOR ANTIBODY; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; MURONOMAB; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG;

EID: 77950965578     PISSN: 00313955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pcl.2010.01.018     Document Type: Review
Times cited : (12)

References (113)
  • 1
    • 77951001783 scopus 로고    scopus 로고
    • NAPRTCS 2008 Annual Report. In: North American Pediatric Renal Trials and Collaborative Studies;
    • Martz K, Stablein DM. NAPRTCS 2008 Annual Report. In: North American Pediatric Renal Trials and Collaborative Studies; 2008.
    • (2008)
    • Martz, K.1    Stablein, D.M.2
  • 2
    • 70349251605 scopus 로고    scopus 로고
    • Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Pediatric Heart Transplantation Report-2009
    • Kirk R., Edwards L.B., Aurora P., et al. Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Pediatric Heart Transplantation Report-2009. J Heart Lung Transplant 2009, 28(10):993-1006.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.10 , pp. 993-1006
    • Kirk, R.1    Edwards, L.B.2    Aurora, P.3
  • 3
    • 70349240683 scopus 로고    scopus 로고
    • Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Pediatric Lung and Heart/Lung Transplantation Report-2009
    • Aurora P., Edwards L.B., Christie J.D., et al. Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Pediatric Lung and Heart/Lung Transplantation Report-2009. J Heart Lung Transplant 2009, 28(10):1023-1030.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.10 , pp. 1023-1030
    • Aurora, P.1    Edwards, L.B.2    Christie, J.D.3
  • 4
    • 58249084373 scopus 로고    scopus 로고
    • Outcomes of 5-year survivors of pediatric liver transplantation: report on 461 children from a North American multicenter registry
    • Ng V.L., Fecteau A., Shepherd R., et al. Outcomes of 5-year survivors of pediatric liver transplantation: report on 461 children from a North American multicenter registry. Pediatrics 2008, 122(6):e1128-e1135.
    • (2008) Pediatrics , vol.122 , Issue.6
    • Ng, V.L.1    Fecteau, A.2    Shepherd, R.3
  • 5
    • 70349562534 scopus 로고    scopus 로고
    • Overview of immunosuppression in liver transplantation
    • Pillai A.A., Levitsky J. Overview of immunosuppression in liver transplantation. World J Gastroenterol 2009, 15(34):4225-4233.
    • (2009) World J Gastroenterol , vol.15 , Issue.34 , pp. 4225-4233
    • Pillai, A.A.1    Levitsky, J.2
  • 6
    • 38549088096 scopus 로고    scopus 로고
    • HLA-mismatched renal transplantation without maintenance immunosuppression
    • Kawai T., Cosimi A.B., Spitzer T.R., et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008, 358(4):353-361.
    • (2008) N Engl J Med , vol.358 , Issue.4 , pp. 353-361
    • Kawai, T.1    Cosimi, A.B.2    Spitzer, T.R.3
  • 7
    • 0033561405 scopus 로고    scopus 로고
    • A randomized, double-blinded comparison of Thymoglobulin versus Atgam for induction immunosuppressive therapy in adult renal transplant recipients
    • Brennan D.C., Flavin K., Lowell J.A., et al. A randomized, double-blinded comparison of Thymoglobulin versus Atgam for induction immunosuppressive therapy in adult renal transplant recipients. Transplantation 1999, 67(7):1011-1018.
    • (1999) Transplantation , vol.67 , Issue.7 , pp. 1011-1018
    • Brennan, D.C.1    Flavin, K.2    Lowell, J.A.3
  • 8
    • 0034965947 scopus 로고    scopus 로고
    • Comparison of polyclonal induction agents in pediatric renal transplantation
    • Brophy P.D., Thomas S.E., McBryde K.D., et al. Comparison of polyclonal induction agents in pediatric renal transplantation. Pediatr Transplant 2001, 5(3):174-178.
    • (2001) Pediatr Transplant , vol.5 , Issue.3 , pp. 174-178
    • Brophy, P.D.1    Thomas, S.E.2    McBryde, K.D.3
  • 9
    • 14644389386 scopus 로고    scopus 로고
    • Induction therapy after cardiac transplantation: a comparison of anti-thymocyte globulin and daclizumab in the prevention of acute rejection
    • Carlsen J., Johansen M., Boesgaard S., et al. Induction therapy after cardiac transplantation: a comparison of anti-thymocyte globulin and daclizumab in the prevention of acute rejection. J Heart Lung Transplant 2005, 24(3):296-302.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.3 , pp. 296-302
    • Carlsen, J.1    Johansen, M.2    Boesgaard, S.3
  • 10
    • 23944465377 scopus 로고    scopus 로고
    • Induction therapy for pediatric and adult heart transplantation: comparison between OKT3 and daclizumab
    • Chin C., Pittson S., Luikart H., et al. Induction therapy for pediatric and adult heart transplantation: comparison between OKT3 and daclizumab. Transplantation 2005, 80(4):477-481.
    • (2005) Transplantation , vol.80 , Issue.4 , pp. 477-481
    • Chin, C.1    Pittson, S.2    Luikart, H.3
  • 11
    • 37549043953 scopus 로고    scopus 로고
    • Alemtuzumab (Campath-1H) in kidney transplantation
    • Ciancio G., Burke G.W. Alemtuzumab (Campath-1H) in kidney transplantation. Am J Transplant 2008, 8(1):15-20.
    • (2008) Am J Transplant , vol.8 , Issue.1 , pp. 15-20
    • Ciancio, G.1    Burke, G.W.2
  • 12
    • 35248887465 scopus 로고    scopus 로고
    • Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab
    • Kirk A.D., Cherikh W.S., Ring M., et al. Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab. Am J Transplant 2007, 7(11):2619-2625.
    • (2007) Am J Transplant , vol.7 , Issue.11 , pp. 2619-2625
    • Kirk, A.D.1    Cherikh, W.S.2    Ring, M.3
  • 13
    • 60849121985 scopus 로고    scopus 로고
    • Use of antibody induction in pediatric renal transplantation
    • Pescovitz M.D. Use of antibody induction in pediatric renal transplantation. Curr Opin Organ Transplant 2008, 13(5):495-499.
    • (2008) Curr Opin Organ Transplant , vol.13 , Issue.5 , pp. 495-499
    • Pescovitz, M.D.1
  • 14
    • 67651176173 scopus 로고    scopus 로고
    • Continuous infusion of thymoglobulin for induction therapy in pediatric heart transplant recipients; experience and outcomes with a novel strategy for administration
    • Pollock-BarZiv S.M., Allain-Rooney T., Manlhiot C., et al. Continuous infusion of thymoglobulin for induction therapy in pediatric heart transplant recipients; experience and outcomes with a novel strategy for administration. Pediatr Transplant 2009, 13(5):585-589.
    • (2009) Pediatr Transplant , vol.13 , Issue.5 , pp. 585-589
    • Pollock-BarZiv, S.M.1    Allain-Rooney, T.2    Manlhiot, C.3
  • 15
    • 58849135828 scopus 로고    scopus 로고
    • Pediatric living donor kidney transplantation under alemtuzumab pretreatment and tacrolimus monotherapy: 4-year experience
    • Tan H.P., Donaldson J., Ellis D., et al. Pediatric living donor kidney transplantation under alemtuzumab pretreatment and tacrolimus monotherapy: 4-year experience. Transplantation 2008, 86(12):1725-1731.
    • (2008) Transplantation , vol.86 , Issue.12 , pp. 1725-1731
    • Tan, H.P.1    Donaldson, J.2    Ellis, D.3
  • 16
    • 38549103672 scopus 로고    scopus 로고
    • Thymoglobulin induction and steroid avoidance in cardiac transplantation: results of a prospective, randomized, controlled study
    • Yamani M.H., Taylor D.O., Czerr J., et al. Thymoglobulin induction and steroid avoidance in cardiac transplantation: results of a prospective, randomized, controlled study. Clin Transplant 2008, 22(1):76-81.
    • (2008) Clin Transplant , vol.22 , Issue.1 , pp. 76-81
    • Yamani, M.H.1    Taylor, D.O.2    Czerr, J.3
  • 17
    • 68949209720 scopus 로고    scopus 로고
    • Delayed graft function is reduced with antithymocyte globulin induction in pediatric kidney transplantation
    • Vilalta R., Lara E., Madrid A., et al. Delayed graft function is reduced with antithymocyte globulin induction in pediatric kidney transplantation. Transplant Proc 2009, 41(6):2373-2375.
    • (2009) Transplant Proc , vol.41 , Issue.6 , pp. 2373-2375
    • Vilalta, R.1    Lara, E.2    Madrid, A.3
  • 18
    • 13444311969 scopus 로고    scopus 로고
    • Use of basiliximab and cyclosporine in heart transplant patients with pre-operative renal dysfunction
    • Delgado D.H., Miriuka S.G., Cusimano R.J., et al. Use of basiliximab and cyclosporine in heart transplant patients with pre-operative renal dysfunction. J Heart Lung Transplant 2005, 24(2):166-169.
    • (2005) J Heart Lung Transplant , vol.24 , Issue.2 , pp. 166-169
    • Delgado, D.H.1    Miriuka, S.G.2    Cusimano, R.J.3
  • 19
    • 73349134261 scopus 로고    scopus 로고
    • Renal-sparing strategies in cardiac transplantation
    • Gustafsson F., Ross H.J. Renal-sparing strategies in cardiac transplantation. Curr Opin Organ Transplant 2009, 14(5):566-570.
    • (2009) Curr Opin Organ Transplant , vol.14 , Issue.5 , pp. 566-570
    • Gustafsson, F.1    Ross, H.J.2
  • 20
    • 34247554345 scopus 로고    scopus 로고
    • Contributions of the Transplant Registry: the 2006 Annual Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
    • Smith J.M., Stablein D.M., Munoz R., et al. Contributions of the Transplant Registry: the 2006 Annual Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). Pediatr Transplant 2007, 11(4):366-373.
    • (2007) Pediatr Transplant , vol.11 , Issue.4 , pp. 366-373
    • Smith, J.M.1    Stablein, D.M.2    Munoz, R.3
  • 21
    • 70349231224 scopus 로고    scopus 로고
    • The Registry of the International Society for Heart and Lung Transplantation: Twenty-Sixth Official Adult Lung and Heart-Lung Transplantation Report-2009
    • Christie J.D., Edwards L.B., Aurora P., et al. The Registry of the International Society for Heart and Lung Transplantation: Twenty-Sixth Official Adult Lung and Heart-Lung Transplantation Report-2009. J Heart Lung Transplant 2009, 28(10):1031-1049.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.10 , pp. 1031-1049
    • Christie, J.D.1    Edwards, L.B.2    Aurora, P.3
  • 22
    • 52949108390 scopus 로고    scopus 로고
    • Induction therapy with thymoglobulin after heart transplantation: impact of therapy duration on lymphocyte depletion and recovery, rejection, and cytomegalovirus infection rates
    • Goland S., Czer L.S., Coleman B., et al. Induction therapy with thymoglobulin after heart transplantation: impact of therapy duration on lymphocyte depletion and recovery, rejection, and cytomegalovirus infection rates. J Heart Lung Transplant 2008, 27(10):1115-1121.
    • (2008) J Heart Lung Transplant , vol.27 , Issue.10 , pp. 1115-1121
    • Goland, S.1    Czer, L.S.2    Coleman, B.3
  • 23
    • 62449171076 scopus 로고    scopus 로고
    • Infectious complications of antilymphocyte therapies in solid organ transplantation
    • Issa N.C., Fishman J.A. Infectious complications of antilymphocyte therapies in solid organ transplantation. Clin Infect Dis 2009, 48(6):772-786.
    • (2009) Clin Infect Dis , vol.48 , Issue.6 , pp. 772-786
    • Issa, N.C.1    Fishman, J.A.2
  • 24
    • 0029973130 scopus 로고    scopus 로고
    • Mechanisms of immunosuppression induced by antithymocyte globulins and OKT3
    • Bonnefoy-Berard N., Revillard J.P. Mechanisms of immunosuppression induced by antithymocyte globulins and OKT3. J Heart Lung Transplant 1996, 15(5):435-442.
    • (1996) J Heart Lung Transplant , vol.15 , Issue.5 , pp. 435-442
    • Bonnefoy-Berard, N.1    Revillard, J.P.2
  • 25
    • 0023837447 scopus 로고
    • Reexposure to OKT3 in renal allograft recipients
    • Mayes J.T., Thistlethwaite J.R., Stuart J.K., et al. Reexposure to OKT3 in renal allograft recipients. Transplantation 1988, 45(2):349-353.
    • (1988) Transplantation , vol.45 , Issue.2 , pp. 349-353
    • Mayes, J.T.1    Thistlethwaite, J.R.2    Stuart, J.K.3
  • 26
    • 0029565168 scopus 로고
    • Side-effects of a monoclonal antibody, muromonab CD3/orthoclone OKT3: bibliographic review
    • Sgro C. Side-effects of a monoclonal antibody, muromonab CD3/orthoclone OKT3: bibliographic review. Toxicology 1995, 105(1):23-29.
    • (1995) Toxicology , vol.105 , Issue.1 , pp. 23-29
    • Sgro, C.1
  • 27
    • 10844244925 scopus 로고    scopus 로고
    • Drug therapy in the heart transplant recipient: part I: cardiac rejection and immunosuppressive drugs
    • Lindenfeld J., Miller G.G., Shakar S.F., et al. Drug therapy in the heart transplant recipient: part I: cardiac rejection and immunosuppressive drugs. Circulation 2004, 110(24):3734-3740.
    • (2004) Circulation , vol.110 , Issue.24 , pp. 3734-3740
    • Lindenfeld, J.1    Miller, G.G.2    Shakar, S.F.3
  • 28
    • 20344364670 scopus 로고    scopus 로고
    • A randomized multicenter trial of OKT3 mAbs induction compared with intravenous cyclosporine in pediatric renal transplantation
    • Benfield M.R., Tejani A., Harmon W.E., et al. A randomized multicenter trial of OKT3 mAbs induction compared with intravenous cyclosporine in pediatric renal transplantation. Pediatr Transplant 2005, 9(3):282-292.
    • (2005) Pediatr Transplant , vol.9 , Issue.3 , pp. 282-292
    • Benfield, M.R.1    Tejani, A.2    Harmon, W.E.3
  • 29
    • 43649094708 scopus 로고    scopus 로고
    • The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2)
    • Lan R.Y., Selmi C., Gershwin M.E. The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2). J Autoimmun 2008, 31(1):7-12.
    • (2008) J Autoimmun , vol.31 , Issue.1 , pp. 7-12
    • Lan, R.Y.1    Selmi, C.2    Gershwin, M.E.3
  • 30
    • 59249104295 scopus 로고    scopus 로고
    • Short-term anti-CD25 monoclonal antibody administration down-regulated CD25 expression without eliminating the neogenetic functional regulatory T cells in kidney transplantation
    • Wang Z., Shi B.Y., Qian Y.Y., et al. Short-term anti-CD25 monoclonal antibody administration down-regulated CD25 expression without eliminating the neogenetic functional regulatory T cells in kidney transplantation. Clin Exp Immunol 2009, 155(3):496-503.
    • (2009) Clin Exp Immunol , vol.155 , Issue.3 , pp. 496-503
    • Wang, Z.1    Shi, B.Y.2    Qian, Y.Y.3
  • 31
    • 70450223686 scopus 로고    scopus 로고
    • Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation
    • Grundy N., Simmonds J., Dawkins H., et al. Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation. J Heart Lung Transplant 2009, 28(12):1279-1284.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.12 , pp. 1279-1284
    • Grundy, N.1    Simmonds, J.2    Dawkins, H.3
  • 32
    • 58149148269 scopus 로고    scopus 로고
    • Pharmacokinetics and immunodynamics of basiliximab in pediatric renal transplant recipients on mycophenolate mofetil comedication
    • Hocker B., Kovarik J.M., Daniel V., et al. Pharmacokinetics and immunodynamics of basiliximab in pediatric renal transplant recipients on mycophenolate mofetil comedication. Transplantation 2008, 86(9):1234-1240.
    • (2008) Transplantation , vol.86 , Issue.9 , pp. 1234-1240
    • Hocker, B.1    Kovarik, J.M.2    Daniel, V.3
  • 33
    • 12144290787 scopus 로고    scopus 로고
    • Monitoring of T-cell subsets in patients treated with anti-CD 25 antibody
    • Praditpornsilpa K., Avihingsanon Y., Kupatawintu P., et al. Monitoring of T-cell subsets in patients treated with anti-CD 25 antibody. Transplant Proc 2004, 36(2 Suppl 1):S487-S491.
    • (2004) Transplant Proc , vol.36 , Issue.1 2 SUPPL
    • Praditpornsilpa, K.1    Avihingsanon, Y.2    Kupatawintu, P.3
  • 34
    • 0031586439 scopus 로고    scopus 로고
    • Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group
    • Nashan B., Moore R., Amlot P., et al. Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. CHIB 201 International Study Group. Lancet 1997, 350(9086):1193-1198.
    • (1997) Lancet , vol.350 , Issue.9086 , pp. 1193-1198
    • Nashan, B.1    Moore, R.2    Amlot, P.3
  • 35
    • 0033608073 scopus 로고    scopus 로고
    • Reduction of the occurrence of acute cellular rejection among renal allograft recipients treated with basiliximab, a chimeric anti-interleukin-2-receptor monoclonal antibody. United States Simulect Renal Study Group
    • Kahan B.D., Rajagopalan P.R., Hall M. Reduction of the occurrence of acute cellular rejection among renal allograft recipients treated with basiliximab, a chimeric anti-interleukin-2-receptor monoclonal antibody. United States Simulect Renal Study Group. Transplantation 1999, 67(2):276-284.
    • (1999) Transplantation , vol.67 , Issue.2 , pp. 276-284
    • Kahan, B.D.1    Rajagopalan, P.R.2    Hall, M.3
  • 36
    • 0033556545 scopus 로고    scopus 로고
    • Reduction of acute renal allograft rejection by daclizumab. Daclizumab Double Therapy Study Group
    • Nashan B., Light S., Hardie I.R., et al. Reduction of acute renal allograft rejection by daclizumab. Daclizumab Double Therapy Study Group. Transplantation 1999, 67(1):110-115.
    • (1999) Transplantation , vol.67 , Issue.1 , pp. 110-115
    • Nashan, B.1    Light, S.2    Hardie, I.R.3
  • 37
    • 0035884619 scopus 로고    scopus 로고
    • Results of 3-year phase III clinical trials with daclizumab prophylaxis for prevention of acute rejection after renal transplantation
    • Bumgardner G.L., Hardie I., Johnson R.W., et al. Results of 3-year phase III clinical trials with daclizumab prophylaxis for prevention of acute rejection after renal transplantation. Transplantation 2001, 72(5):839-845.
    • (2001) Transplantation , vol.72 , Issue.5 , pp. 839-845
    • Bumgardner, G.L.1    Hardie, I.2    Johnson, R.W.3
  • 38
    • 51849113850 scopus 로고    scopus 로고
    • Basiliximab induction therapy for live donor kidney transplantation: a long-term follow-up of prospective randomized controlled study
    • Sheashaa H.A., Bakr M.A., Ismail A.M., et al. Basiliximab induction therapy for live donor kidney transplantation: a long-term follow-up of prospective randomized controlled study. Clin Exp Nephrol 2008, 12(5):376-381.
    • (2008) Clin Exp Nephrol , vol.12 , Issue.5 , pp. 376-381
    • Sheashaa, H.A.1    Bakr, M.A.2    Ismail, A.M.3
  • 39
    • 84921703405 scopus 로고    scopus 로고
    • Interleukin 2 receptor antagonists for kidney transplant recipients
    • CD003897
    • Webster A.C., Playford E.G., Higgins G., et al. Interleukin 2 receptor antagonists for kidney transplant recipients. Cochrane Database Syst Rev 2004, (1). CD003897.
    • (2004) Cochrane Database Syst Rev , Issue.1
    • Webster, A.C.1    Playford, E.G.2    Higgins, G.3
  • 40
    • 47649088198 scopus 로고    scopus 로고
    • Interleukin-2 receptor antagonists as induction therapy after heart transplantation: systematic review with meta-analysis of randomized trials
    • Moller C.H., Gustafsson F., Gluud C., et al. Interleukin-2 receptor antagonists as induction therapy after heart transplantation: systematic review with meta-analysis of randomized trials. J Heart Lung Transplant 2008, 27(8):835-842.
    • (2008) J Heart Lung Transplant , vol.27 , Issue.8 , pp. 835-842
    • Moller, C.H.1    Gustafsson, F.2    Gluud, C.3
  • 41
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N., DiDonato J.A., Rosette C., et al. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995, 270(5234):286-290.
    • (1995) Science , vol.270 , Issue.5234 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3
  • 42
    • 68849100098 scopus 로고    scopus 로고
    • Corticosteroid-free immunosuppression in liver transplantation: a meta-analysis and meta-regression of outcomes
    • Sgourakis G., Radtke A., Fouzas I., et al. Corticosteroid-free immunosuppression in liver transplantation: a meta-analysis and meta-regression of outcomes. Transpl Int 2009, 22(9):892-905.
    • (2009) Transpl Int , vol.22 , Issue.9 , pp. 892-905
    • Sgourakis, G.1    Radtke, A.2    Fouzas, I.3
  • 43
    • 68849094348 scopus 로고    scopus 로고
    • Steroid avoidance or withdrawal for kidney transplant recipients
    • CD005632
    • Pascual J., Zamora J., Galeano C., et al. Steroid avoidance or withdrawal for kidney transplant recipients. Cochrane Database Syst Rev 2009, (1). CD005632.
    • (2009) Cochrane Database Syst Rev , Issue.1
    • Pascual, J.1    Zamora, J.2    Galeano, C.3
  • 44
    • 42149194286 scopus 로고    scopus 로고
    • Steroid-free, tacrolimus-basiliximab immunosuppression in pediatric liver transplantation: clinical and pharmacoeconomic study in 50 children
    • Gras J.M., Gerkens S., Beguin C., et al. Steroid-free, tacrolimus-basiliximab immunosuppression in pediatric liver transplantation: clinical and pharmacoeconomic study in 50 children. Liver Transpl 2008, 14(4):469-477.
    • (2008) Liver Transpl , vol.14 , Issue.4 , pp. 469-477
    • Gras, J.M.1    Gerkens, S.2    Beguin, C.3
  • 45
    • 0242491816 scopus 로고    scopus 로고
    • Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation
    • Sarwal M.M., Vidhun J.R., Alexander S.R., et al. Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation. Transplantation 2003, 76(9):1331-1339.
    • (2003) Transplantation , vol.76 , Issue.9 , pp. 1331-1339
    • Sarwal, M.M.1    Vidhun, J.R.2    Alexander, S.R.3
  • 46
    • 0001018554 scopus 로고
    • Calcineurin: a calcium- and calmodulin-binding protein of the nervous system
    • Klee C.B., Crouch T.H., Krinks M.H. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc Natl Acad Sci U S A 1979, 76(12):6270-6273.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , Issue.12 , pp. 6270-6273
    • Klee, C.B.1    Crouch, T.H.2    Krinks, M.H.3
  • 47
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J., Farmer J.D., Lane W.S., et al. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66(4):807-815.
    • (1991) Cell , vol.66 , Issue.4 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3
  • 48
    • 0017157814 scopus 로고
    • Biological effects of cyclosporin A: a new antilymphocytic agent
    • Borel J.F., Feurer C., Gubler H.U., et al. Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions 1976, 6(4):468-475.
    • (1976) Agents Actions , vol.6 , Issue.4 , pp. 468-475
    • Borel, J.F.1    Feurer, C.2    Gubler, H.U.3
  • 49
    • 0019491260 scopus 로고
    • Cyclosporin A in cadaveric organ transplantation
    • Calne R.Y., White D.J., Evans D.B., et al. Cyclosporin A in cadaveric organ transplantation. Br Med J (Clin Res Ed) 1981, 282(6268):934-936.
    • (1981) Br Med J (Clin Res Ed) , vol.282 , Issue.6268 , pp. 934-936
    • Calne, R.Y.1    White, D.J.2    Evans, D.B.3
  • 50
    • 0023261356 scopus 로고
    • FK-506, a novel immunosuppressant isolated from a streptomyces. II. Immunosuppressive effect of FK-506 in vitro
    • Kino T., Hatanaka H., Miyata S., et al. FK-506, a novel immunosuppressant isolated from a streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot (Tokyo) 1987, 40(9):1256-1265.
    • (1987) J Antibiot (Tokyo) , vol.40 , Issue.9 , pp. 1256-1265
    • Kino, T.1    Hatanaka, H.2    Miyata, S.3
  • 51
    • 0036175307 scopus 로고    scopus 로고
    • Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
    • Cummins C.L., Jacobsen W., Benet L.Z. Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002, 300(3):1036-1045.
    • (2002) J Pharmacol Exp Ther , vol.300 , Issue.3 , pp. 1036-1045
    • Cummins, C.L.1    Jacobsen, W.2    Benet, L.Z.3
  • 52
    • 68449084545 scopus 로고    scopus 로고
    • New insights into the pharmacokinetics and pharmacodynamics of the calcineurin inhibitors and mycophenolic acid: possible consequences for therapeutic drug monitoring in solid organ transplantation
    • de Jonge H., Naesens M., Kuypers D.R. New insights into the pharmacokinetics and pharmacodynamics of the calcineurin inhibitors and mycophenolic acid: possible consequences for therapeutic drug monitoring in solid organ transplantation. Ther Drug Monit 2009, 31(4):416-435.
    • (2009) Ther Drug Monit , vol.31 , Issue.4 , pp. 416-435
    • de Jonge, H.1    Naesens, M.2    Kuypers, D.R.3
  • 53
    • 47249151375 scopus 로고    scopus 로고
    • Pharmacogenetics of immunosuppressants: progress, pitfalls and promises
    • Cattaneo D., Baldelli S., Perico N. Pharmacogenetics of immunosuppressants: progress, pitfalls and promises. Am J Transplant 2008, 8(7):1374-1383.
    • (2008) Am J Transplant , vol.8 , Issue.7 , pp. 1374-1383
    • Cattaneo, D.1    Baldelli, S.2    Perico, N.3
  • 54
    • 34250792130 scopus 로고    scopus 로고
    • The clinical benefits of cyclosporine C2-level monitoring: a systematic review
    • Knight S.R., Morris P.J. The clinical benefits of cyclosporine C2-level monitoring: a systematic review. Transplantation 2007, 83(12):1525-1535.
    • (2007) Transplantation , vol.83 , Issue.12 , pp. 1525-1535
    • Knight, S.R.1    Morris, P.J.2
  • 55
    • 0036380025 scopus 로고    scopus 로고
    • Mechanisms of clinically relevant drug interactions associated with tacrolimus
    • Christians U., Jacobsen W., Benet L.Z., et al. Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet 2002, 41(11):813-851.
    • (2002) Clin Pharmacokinet , vol.41 , Issue.11 , pp. 813-851
    • Christians, U.1    Jacobsen, W.2    Benet, L.Z.3
  • 56
    • 33746867060 scopus 로고    scopus 로고
    • Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity
    • Tonshoff B., Hocker B. Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity. Pediatr Transplant 2006, 10(6):721-729.
    • (2006) Pediatr Transplant , vol.10 , Issue.6 , pp. 721-729
    • Tonshoff, B.1    Hocker, B.2
  • 57
    • 33644876434 scopus 로고    scopus 로고
    • Tacrolimus versus cyclosporin as primary immunosuppression for kidney transplant recipients
    • CD003961
    • Webster A., Woodroffe R.C., Taylor R.S., et al. Tacrolimus versus cyclosporin as primary immunosuppression for kidney transplant recipients. Cochrane Database Syst Rev 2005, (4). CD003961.
    • (2005) Cochrane Database Syst Rev , Issue.4
    • Webster, A.1    Woodroffe, R.C.2    Taylor, R.S.3
  • 58
    • 42749098080 scopus 로고    scopus 로고
    • Cyclosporin versus tacrolimus for liver transplanted patients
    • CD005161
    • Haddad E.M., McAlister V.C., Renouf E., et al. Cyclosporin versus tacrolimus for liver transplanted patients. Cochrane Database Syst Rev 2006, (4). CD005161.
    • (2006) Cochrane Database Syst Rev , Issue.4
    • Haddad, E.M.1    McAlister, V.C.2    Renouf, E.3
  • 59
    • 58149166707 scopus 로고    scopus 로고
    • Tacrolimus versus cyclosporine microemulsion for heart transplant recipients: a meta-analysis
    • Ye F., Ying-Bin X., Yu-Guo W., et al. Tacrolimus versus cyclosporine microemulsion for heart transplant recipients: a meta-analysis. J Heart Lung Transplant 2009, 28(1):58-66.
    • (2009) J Heart Lung Transplant , vol.28 , Issue.1 , pp. 58-66
    • Ye, F.1    Ying-Bin, X.2    Yu-Guo, W.3
  • 60
    • 67249093754 scopus 로고    scopus 로고
    • Tacrolimus versus cyclosporine for adult lung transplant recipients: a meta-analysis
    • Fan Y., Xiao Y.B., Weng Y.G. Tacrolimus versus cyclosporine for adult lung transplant recipients: a meta-analysis. Transplant Proc 2009, 41(5):1821-1824.
    • (2009) Transplant Proc , vol.41 , Issue.5 , pp. 1821-1824
    • Fan, Y.1    Xiao, Y.B.2    Weng, Y.G.3
  • 61
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograft nephropathy
    • Nankivell B.J., Borrows R.J., Fung C.L., et al. The natural history of chronic allograft nephropathy. N Engl J Med 2003, 349(24):2326-2333.
    • (2003) N Engl J Med , vol.349 , Issue.24 , pp. 2326-2333
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 62
    • 65649141582 scopus 로고    scopus 로고
    • Mycophenolate and sirolimus as calcineurin inhibitor-free immunosuppression improves renal function better than calcineurin inhibitor-reduction in late cardiac transplant recipients with chronic renal failure
    • Groetzner J., Kaczmarek I., Schulz U., et al. Mycophenolate and sirolimus as calcineurin inhibitor-free immunosuppression improves renal function better than calcineurin inhibitor-reduction in late cardiac transplant recipients with chronic renal failure. Transplantation 2009, 87(5):726-733.
    • (2009) Transplantation , vol.87 , Issue.5 , pp. 726-733
    • Groetzner, J.1    Kaczmarek, I.2    Schulz, U.3
  • 63
    • 4644281980 scopus 로고    scopus 로고
    • Severe elevations of FK506 blood concentration due to diarrhea in renal transplant recipients
    • Sato K., Amada N., Sato T., et al. Severe elevations of FK506 blood concentration due to diarrhea in renal transplant recipients. Clin Transplant 2004, 18(5):585-590.
    • (2004) Clin Transplant , vol.18 , Issue.5 , pp. 585-590
    • Sato, K.1    Amada, N.2    Sato, T.3
  • 65
    • 70349306711 scopus 로고    scopus 로고
    • Organ transplant recipients and skin cancer: assessment of risk factors with focus on sun exposure
    • Terhorst D., Drecoll U., Stockfleth E., et al. Organ transplant recipients and skin cancer: assessment of risk factors with focus on sun exposure. Br J Dermatol 2009, 161(Suppl 3):85-89.
    • (2009) Br J Dermatol , vol.161 , Issue.3 SUPPL , pp. 85-89
    • Terhorst, D.1    Drecoll, U.2    Stockfleth, E.3
  • 66
    • 84944372802 scopus 로고
    • Heart transplantation. Four years' experience with conventional immunosuppression
    • Copeland J.G., Mammana R.B., Fuller J.K., et al. Heart transplantation. Four years' experience with conventional immunosuppression. JAMA 1984, 251(12):1563-1566.
    • (1984) JAMA , vol.251 , Issue.12 , pp. 1563-1566
    • Copeland, J.G.1    Mammana, R.B.2    Fuller, J.K.3
  • 67
    • 0028577228 scopus 로고
    • RS-61443: a new immunosuppressive agent
    • Young C.J., Sollinger H.W. RS-61443: a new immunosuppressive agent. Transplant Proc 1994, 26(6):3144-3146.
    • (1994) Transplant Proc , vol.26 , Issue.6 , pp. 3144-3146
    • Young, C.J.1    Sollinger, H.W.2
  • 68
    • 0034045586 scopus 로고    scopus 로고
    • Mycophenolate mofetil and its mechanisms of action
    • Allison A.C., Eugui E.M. Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 2000, 47(2-3):85-118.
    • (2000) Immunopharmacology , vol.47 , Issue.2-3 , pp. 85-118
    • Allison, A.C.1    Eugui, E.M.2
  • 69
    • 27644521264 scopus 로고    scopus 로고
    • Review of major clinical trials with mycophenolate mofetil in cardiac transplantation
    • Kobashigawa J.A., Meiser B.M. Review of major clinical trials with mycophenolate mofetil in cardiac transplantation. Transplantation 2005, 80(2 Suppl):S235-S243.
    • (2005) Transplantation , vol.80 , Issue.2 SUPPL
    • Kobashigawa, J.A.1    Meiser, B.M.2
  • 70
    • 0029115531 scopus 로고
    • Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group
    • Sollinger H.W. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation 1995, 60(3):225-232.
    • (1995) Transplantation , vol.60 , Issue.3 , pp. 225-232
    • Sollinger, H.W.1
  • 71
    • 0006986048 scopus 로고    scopus 로고
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation 1996, 61(7):1029-1037.
    • (1996) Transplantation , vol.61 , Issue.7 , pp. 1029-1037
  • 72
    • 0032526253 scopus 로고    scopus 로고
    • A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: results at three years. Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • Mathew T.H. A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: results at three years. Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation 1998, 65(11):1450-1454.
    • (1998) Transplantation , vol.65 , Issue.11 , pp. 1450-1454
    • Mathew, T.H.1
  • 73
    • 65549153182 scopus 로고    scopus 로고
    • Mycophenolate mofetil decreases acute rejection and may improve graft survival in renal transplant recipients when compared with azathioprine: a systematic review
    • Knight S.R., Russell N.K., Barcena L., et al. Mycophenolate mofetil decreases acute rejection and may improve graft survival in renal transplant recipients when compared with azathioprine: a systematic review. Transplantation 2009, 87(6):785-794.
    • (2009) Transplantation , vol.87 , Issue.6 , pp. 785-794
    • Knight, S.R.1    Russell, N.K.2    Barcena, L.3
  • 74
    • 67650938464 scopus 로고    scopus 로고
    • Azathioprine in liver transplantation: a reevaluation of its use and a comparison with mycophenolate mofetil
    • Germani G., Pleguezuelo M., Villamil F., et al. Azathioprine in liver transplantation: a reevaluation of its use and a comparison with mycophenolate mofetil. Am J Transplant 2009, 9(8):1725-1731.
    • (2009) Am J Transplant , vol.9 , Issue.8 , pp. 1725-1731
    • Germani, G.1    Pleguezuelo, M.2    Villamil, F.3
  • 75
    • 34249873239 scopus 로고    scopus 로고
    • Mycophenolate mofetil versus azathioprine for prevention of chronic allograft dysfunction in renal transplantation: the MYSS follow-up randomized, controlled clinical trial
    • Remuzzi G., Cravedi P., Costantini M., et al. Mycophenolate mofetil versus azathioprine for prevention of chronic allograft dysfunction in renal transplantation: the MYSS follow-up randomized, controlled clinical trial. J Am Soc Nephrol 2007, 18(6):1973-1985.
    • (2007) J Am Soc Nephrol , vol.18 , Issue.6 , pp. 1973-1985
    • Remuzzi, G.1    Cravedi, P.2    Costantini, M.3
  • 76
    • 72449180378 scopus 로고    scopus 로고
    • Mycophenolate mofetil versus azathioprine in organ transplantation
    • Cravedi P., Perna A., Ruggenenti P., et al. Mycophenolate mofetil versus azathioprine in organ transplantation. Am J Transplant 2009, 9(12):2856-2857.
    • (2009) Am J Transplant , vol.9 , Issue.12 , pp. 2856-2857
    • Cravedi, P.1    Perna, A.2    Ruggenenti, P.3
  • 77
    • 0037468452 scopus 로고    scopus 로고
    • Pediatric renal transplantation with mycophenolate mofetil-based immunosuppression without induction: results after three years
    • Jungraithmayr T., Staskewitz A., Kirste G., et al. Pediatric renal transplantation with mycophenolate mofetil-based immunosuppression without induction: results after three years. Transplantation 2003, 75(4):454-461.
    • (2003) Transplantation , vol.75 , Issue.4 , pp. 454-461
    • Jungraithmayr, T.1    Staskewitz, A.2    Kirste, G.3
  • 78
    • 34247623537 scopus 로고    scopus 로고
    • Five-year outcome in pediatric patients with mycophenolate mofetil-based renal transplantation
    • Jungraithmayr T.C., Wiesmayr S., Staskewitz A., et al. Five-year outcome in pediatric patients with mycophenolate mofetil-based renal transplantation. Transplantation 2007, 83(7):900-905.
    • (2007) Transplantation , vol.83 , Issue.7 , pp. 900-905
    • Jungraithmayr, T.C.1    Wiesmayr, S.2    Staskewitz, A.3
  • 79
    • 0035868387 scopus 로고    scopus 로고
    • Mycophenolate mofetil in pediatric renal transplantation without induction therapy: results after 12 months of treatment. German Pediatric Renal Transplantation Study Group
    • Staskewitz A., Kirste G., Tonshoff B., et al. Mycophenolate mofetil in pediatric renal transplantation without induction therapy: results after 12 months of treatment. German Pediatric Renal Transplantation Study Group. Transplantation 2001, 71(5):638-644.
    • (2001) Transplantation , vol.71 , Issue.5 , pp. 638-644
    • Staskewitz, A.1    Kirste, G.2    Tonshoff, B.3
  • 80
    • 0032903614 scopus 로고    scopus 로고
    • Mycophenolate mofetil in pediatric renal transplantation
    • Benfield M.R., Symons J.M., Bynon S., et al. Mycophenolate mofetil in pediatric renal transplantation. Pediatr Transplant 1999, 3(1):33-37.
    • (1999) Pediatr Transplant , vol.3 , Issue.1 , pp. 33-37
    • Benfield, M.R.1    Symons, J.M.2    Bynon, S.3
  • 81
    • 33646494020 scopus 로고    scopus 로고
    • Preventing cardiac allograft vasculopathy: long-term beneficial effects of mycophenolate mofetil
    • Kaczmarek I., Ertl B., Schmauss D., et al. Preventing cardiac allograft vasculopathy: long-term beneficial effects of mycophenolate mofetil. J Heart Lung Transplant 2006, 25(5):550-556.
    • (2006) J Heart Lung Transplant , vol.25 , Issue.5 , pp. 550-556
    • Kaczmarek, I.1    Ertl, B.2    Schmauss, D.3
  • 82
    • 34249317220 scopus 로고    scopus 로고
    • Low-dose tacrolimus/sirolimus and steroid withdrawal in heart recipients is highly efficacious
    • Meiser B., Kaczmarek I., Mueller M., et al. Low-dose tacrolimus/sirolimus and steroid withdrawal in heart recipients is highly efficacious. J Heart Lung Transplant 2007, 26(6):598-603.
    • (2007) J Heart Lung Transplant , vol.26 , Issue.6 , pp. 598-603
    • Meiser, B.1    Kaczmarek, I.2    Mueller, M.3
  • 83
    • 33747119649 scopus 로고    scopus 로고
    • Long-term safety and efficacy after conversion of maintenance renal transplant recipients from mycophenolate mofetil (MMF) to enteric-coated mycophenolate sodium (EC-MPA, myfortic)
    • Budde K., Knoll G., Curtis J., et al. Long-term safety and efficacy after conversion of maintenance renal transplant recipients from mycophenolate mofetil (MMF) to enteric-coated mycophenolate sodium (EC-MPA, myfortic). Clin Nephrol 2006, 66(2):103-111.
    • (2006) Clin Nephrol , vol.66 , Issue.2 , pp. 103-111
    • Budde, K.1    Knoll, G.2    Curtis, J.3
  • 84
    • 33746473566 scopus 로고    scopus 로고
    • Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) compared with mycophenolate mofetil (MMF) in de novo heart transplant recipients: results of a 12-month, single-blind, randomized, parallel-group, multicenter study
    • Kobashigawa J.A., Renlund D.G., Gerosa G., et al. Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) compared with mycophenolate mofetil (MMF) in de novo heart transplant recipients: results of a 12-month, single-blind, randomized, parallel-group, multicenter study. J Heart Lung Transplant 2006, 25(8):935-941.
    • (2006) J Heart Lung Transplant , vol.25 , Issue.8 , pp. 935-941
    • Kobashigawa, J.A.1    Renlund, D.G.2    Gerosa, G.3
  • 85
    • 62849111963 scopus 로고    scopus 로고
    • Successful conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium (myfortic) in liver transplant patients with gastrointestinal side effects
    • Robaeys G., Cassiman D., Verslype C., et al. Successful conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium (myfortic) in liver transplant patients with gastrointestinal side effects. Transplant Proc 2009, 41(2):610-613.
    • (2009) Transplant Proc , vol.41 , Issue.2 , pp. 610-613
    • Robaeys, G.1    Cassiman, D.2    Verslype, C.3
  • 86
    • 51249096080 scopus 로고    scopus 로고
    • Conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in renal transplant recipients with gastrointestinal tract disorders
    • Darji P., Vijayaraghavan R., Thiagarajan C.M., et al. Conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in renal transplant recipients with gastrointestinal tract disorders. Transplant Proc 2008, 40(7):2262-2267.
    • (2008) Transplant Proc , vol.40 , Issue.7 , pp. 2262-2267
    • Darji, P.1    Vijayaraghavan, R.2    Thiagarajan, C.M.3
  • 87
    • 67349179645 scopus 로고    scopus 로고
    • Tetrada of the possible mycophenolate mofetil embryopathy: a review
    • Merlob P., Stahl B., Klinger G. Tetrada of the possible mycophenolate mofetil embryopathy: a review. Reprod Toxicol 2009, 28(1):105-108.
    • (2009) Reprod Toxicol , vol.28 , Issue.1 , pp. 105-108
    • Merlob, P.1    Stahl, B.2    Klinger, G.3
  • 88
    • 33845719435 scopus 로고    scopus 로고
    • Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients
    • Johnston A., He X., Holt D.W. Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients. Transplantation 2006, 82(11):1413-1418.
    • (2006) Transplantation , vol.82 , Issue.11 , pp. 1413-1418
    • Johnston, A.1    He, X.2    Holt, D.W.3
  • 89
    • 0038298273 scopus 로고    scopus 로고
    • Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: a prospective study in 100 de novo renal allograft recipients
    • Kuypers D.R., Claes K., Evenepoel P., et al. Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: a prospective study in 100 de novo renal allograft recipients. J Clin Pharmacol 2003, 43(8):866-880.
    • (2003) J Clin Pharmacol , vol.43 , Issue.8 , pp. 866-880
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3
  • 90
    • 20044390198 scopus 로고    scopus 로고
    • Population pharmacokinetics of mycophenolic acid in kidney transplant pediatric and adolescent patients
    • Payen S., Zhang D., Maisin A., et al. Population pharmacokinetics of mycophenolic acid in kidney transplant pediatric and adolescent patients. Ther Drug Monit 2005, 27(3):378-388.
    • (2005) Ther Drug Monit , vol.27 , Issue.3 , pp. 378-388
    • Payen, S.1    Zhang, D.2    Maisin, A.3
  • 91
    • 55949130835 scopus 로고    scopus 로고
    • Comparing mycophenolate mofetil regimens for de novo renal transplant recipients: the fixed-dose concentration-controlled trial
    • van Gelder T., Silva H.T., de Fijter J.W., et al. Comparing mycophenolate mofetil regimens for de novo renal transplant recipients: the fixed-dose concentration-controlled trial. Transplantation 2008, 86(8):1043-1051.
    • (2008) Transplantation , vol.86 , Issue.8 , pp. 1043-1051
    • van Gelder, T.1    Silva, H.T.2    de Fijter, J.W.3
  • 92
    • 68449083304 scopus 로고    scopus 로고
    • Mycophenolic acid 12-hour area under the curve in de novo liver transplant patients given mycophenolate mofetil at fixed versus concentration-controlled doses
    • Kamar N., Marquet P., Gandia P., et al. Mycophenolic acid 12-hour area under the curve in de novo liver transplant patients given mycophenolate mofetil at fixed versus concentration-controlled doses. Ther Drug Monit 2009, 31(4):451-456.
    • (2009) Ther Drug Monit , vol.31 , Issue.4 , pp. 451-456
    • Kamar, N.1    Marquet, P.2    Gandia, P.3
  • 93
    • 34547907805 scopus 로고    scopus 로고
    • Expanding mTOR signaling
    • Yang Q., Guan K.L. Expanding mTOR signaling. Cell Res 2007, 17(8):666-681.
    • (2007) Cell Res , vol.17 , Issue.8 , pp. 666-681
    • Yang, Q.1    Guan, K.L.2
  • 94
    • 72449147738 scopus 로고    scopus 로고
    • The multifunctional role of mTOR in innate immunity: implications for transplant immunity
    • Saemann M.D., Haidinger M., Hecking M., et al. The multifunctional role of mTOR in innate immunity: implications for transplant immunity. Am J Transplant 2009, 9(12):2655-2661.
    • (2009) Am J Transplant , vol.9 , Issue.12 , pp. 2655-2661
    • Saemann, M.D.1    Haidinger, M.2    Hecking, M.3
  • 95
    • 20844461132 scopus 로고    scopus 로고
    • Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial
    • Keogh A., Richardson M., Ruygrok P., et al. Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial. Circulation 2004, 110(17):2694-2700.
    • (2004) Circulation , vol.110 , Issue.17 , pp. 2694-2700
    • Keogh, A.1    Richardson, M.2    Ruygrok, P.3
  • 96
    • 0016724057 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle
    • Vezina C., Kudelski A., Sehgal S.N. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 1975, 28(10):721-726.
    • (1975) J Antibiot (Tokyo) , vol.28 , Issue.10 , pp. 721-726
    • Vezina, C.1    Kudelski, A.2    Sehgal, S.N.3
  • 97
    • 33750593383 scopus 로고    scopus 로고
    • Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy
    • Schachter A.D., Benfield M.R., Wyatt R.J., et al. Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy. Pediatr Transplant 2006, 10(8):914-919.
    • (2006) Pediatr Transplant , vol.10 , Issue.8 , pp. 914-919
    • Schachter, A.D.1    Benfield, M.R.2    Wyatt, R.J.3
  • 98
    • 13144256680 scopus 로고    scopus 로고
    • The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent
    • Kaplan B., Meier-Kriesche H.U., Napoli K.L., et al. The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent. Clin Pharmacol Ther 1998, 63(1):48-53.
    • (1998) Clin Pharmacol Ther , vol.63 , Issue.1 , pp. 48-53
    • Kaplan, B.1    Meier-Kriesche, H.U.2    Napoli, K.L.3
  • 99
    • 33847235398 scopus 로고    scopus 로고
    • Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview
    • Huyghe E., Zairi A., Nohra J., et al. Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview. Transpl Int 2007, 20(4):305-311.
    • (2007) Transpl Int , vol.20 , Issue.4 , pp. 305-311
    • Huyghe, E.1    Zairi, A.2    Nohra, J.3
  • 100
    • 33745029538 scopus 로고    scopus 로고
    • Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients
    • CD004756
    • Webster A., Pankhurst T., Rinaldi F., et al. Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients. Cochrane Database Syst Rev 2006, (2). CD004756.
    • (2006) Cochrane Database Syst Rev , Issue.2
    • Webster, A.1    Pankhurst, T.2    Rinaldi, F.3
  • 101
    • 33646384606 scopus 로고    scopus 로고
    • Monoclonal and polyclonal antibody therapy for treating acute rejection in kidney transplant recipients: a systematic review of randomized trial data
    • Webster A.C., Pankhurst T., Rinaldi F., et al. Monoclonal and polyclonal antibody therapy for treating acute rejection in kidney transplant recipients: a systematic review of randomized trial data. Transplantation 2006, 81(7):953-965.
    • (2006) Transplantation , vol.81 , Issue.7 , pp. 953-965
    • Webster, A.C.1    Pankhurst, T.2    Rinaldi, F.3
  • 102
    • 11144354110 scopus 로고    scopus 로고
    • International experience with conversion from cyclosporine to tacrolimus for acute and chronic lung allograft rejection
    • Sarahrudi K., Estenne M., Corris P., et al. International experience with conversion from cyclosporine to tacrolimus for acute and chronic lung allograft rejection. J Thorac Cardiovasc Surg 2004, 127(4):1126-1132.
    • (2004) J Thorac Cardiovasc Surg , vol.127 , Issue.4 , pp. 1126-1132
    • Sarahrudi, K.1    Estenne, M.2    Corris, P.3
  • 103
    • 0035993780 scopus 로고    scopus 로고
    • Conversion of cyclosporine to tacrolimus for refractory or persistent myocardial rejection
    • Chan M.C., Kwok B.W., Shiba N., et al. Conversion of cyclosporine to tacrolimus for refractory or persistent myocardial rejection. Transplant Proc 2002, 34(5):1850-1852.
    • (2002) Transplant Proc , vol.34 , Issue.5 , pp. 1850-1852
    • Chan, M.C.1    Kwok, B.W.2    Shiba, N.3
  • 104
    • 74349101176 scopus 로고    scopus 로고
    • Proteasome inhibition for antibody-mediated rejection
    • Everly J.J., Walsh R.C., Alloway R.R., et al. Proteasome inhibition for antibody-mediated rejection. Curr Opin Organ Transplant 2009, 14(6):662-666.
    • (2009) Curr Opin Organ Transplant , vol.14 , Issue.6 , pp. 662-666
    • Everly, J.J.1    Walsh, R.C.2    Alloway, R.R.3
  • 105
    • 75749083746 scopus 로고    scopus 로고
    • Deciphering antibody-mediated rejection: new insights into mechanisms and treatment
    • Stegall M.D., Gloor J.M. Deciphering antibody-mediated rejection: new insights into mechanisms and treatment. Curr Opin Organ Transplant 2009, 15(1):8-10.
    • (2009) Curr Opin Organ Transplant , vol.15 , Issue.1 , pp. 8-10
    • Stegall, M.D.1    Gloor, J.M.2
  • 106
    • 0034501632 scopus 로고    scopus 로고
    • Campath-1H monoclonal antibody therapy
    • Flynn J.M., Byrd J.C. Campath-1H monoclonal antibody therapy. Curr Opin Oncol 2000, 12(6):574-581.
    • (2000) Curr Opin Oncol , vol.12 , Issue.6 , pp. 574-581
    • Flynn, J.M.1    Byrd, J.C.2
  • 107
    • 41049115598 scopus 로고    scopus 로고
    • A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-up
    • Ciancio G., Burke G.W., Gaynor J.J., et al. A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-up. Clin Transplant 2008, 22(2):200-210.
    • (2008) Clin Transplant , vol.22 , Issue.2 , pp. 200-210
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3
  • 108
    • 75149189508 scopus 로고    scopus 로고
    • Alemtuzumab induction prior to cardiac transplantation with lower intensity maintenance immunosuppression: one-year outcomes
    • Teuteberg J.J., Shullo M.A., Zomak R., et al. Alemtuzumab induction prior to cardiac transplantation with lower intensity maintenance immunosuppression: one-year outcomes. Am J Transplant 2010, 10(2):382-388.
    • (2010) Am J Transplant , vol.10 , Issue.2 , pp. 382-388
    • Teuteberg, J.J.1    Shullo, M.A.2    Zomak, R.3
  • 109
    • 0031727486 scopus 로고    scopus 로고
    • The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells
    • McAdam A.J., Schweitzer A.N., Sharpe A.H. The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells. Immunol Rev 1998, 165:231-247.
    • (1998) Immunol Rev , vol.165 , pp. 231-247
    • McAdam, A.J.1    Schweitzer, A.N.2    Sharpe, A.H.3
  • 110
    • 33748416499 scopus 로고    scopus 로고
    • Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
    • Suntharalingam G., Perry M.R., Ward S., et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med 2006, 355(10):1018-1028.
    • (2006) N Engl J Med , vol.355 , Issue.10 , pp. 1018-1028
    • Suntharalingam, G.1    Perry, M.R.2    Ward, S.3
  • 111
    • 38949173232 scopus 로고    scopus 로고
    • Costimulation blockade in autoimmunity and transplantation
    • [quiz: 7-8]
    • Vincenti F. Costimulation blockade in autoimmunity and transplantation. J Allergy Clin Immunol 2008, 121(2):299-306. [quiz: 7-8].
    • (2008) J Allergy Clin Immunol , vol.121 , Issue.2 , pp. 299-306
    • Vincenti, F.1
  • 112
    • 23944502334 scopus 로고    scopus 로고
    • Costimulation blockade with belatacept in renal transplantation
    • Vincenti F., Larsen C., Durrbach A., et al. Costimulation blockade with belatacept in renal transplantation. N Engl J Med 2005, 353(8):770-781.
    • (2005) N Engl J Med , vol.353 , Issue.8 , pp. 770-781
    • Vincenti, F.1    Larsen, C.2    Durrbach, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.