메뉴 건너뛰기




Volumn 8, Issue 1, 2008, Pages 15-20

Alemtuzumab (Campath-1H) in kidney transplantation

Author keywords

Acute rejection; Alemtuzumab; Induction therapy; Mycophenolate mofetil; Renal allograft; Sirolimus; Tacrolimus

Indexed keywords

15 DEOXYSPERGUALIN; ALEMTUZUMAB; BASILIXIMAB; CALCINEURIN INHIBITOR; CYCLOSPORIN A; CYTOMEGALOVIRUS ANTIBODY; DACLIZUMAB; IMMUNOGLOBULIN G1; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; RITUXIMAB; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 37549043953     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.02053.x     Document Type: Short Survey
Times cited : (60)

References (41)
  • 1
    • 0031001622 scopus 로고    scopus 로고
    • A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation
    • Pirsch JD, Miller J, Deierhoi MH, Vicenti F, Filo R. A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation. Transplantation 1997 63 : 977 983.
    • (1997) Transplantation , vol.63 , pp. 977-983
    • Pirsch, J.D.1    Miller, J.2    Deierhoi, M.H.3    Vicenti, F.4    Filo, R.5
  • 2
    • 0037091031 scopus 로고    scopus 로고
    • Daclizumab induction, tacrolimus, mycophenolate mofetil and steroids as an immunosuppression regimen for primary kidney transplant recipients
    • Ciancio G, Burke GW, Suzart K et al. Daclizumab induction, tacrolimus, mycophenolate mofetil and steroids as an immunosuppression regimen for primary kidney transplant recipients. Transplantation 2002 73 : 1100 1106.
    • (2002) Transplantation , vol.73 , pp. 1100-1106
    • Ciancio, G.1    Burke, G.W.2    Suzart, K.3
  • 4
    • 3542995707 scopus 로고    scopus 로고
    • Long-term renal allograft survival: Have we made significant progress or is it time to rethink our analytic and therapeutic strategies?
    • Meier-Kriesche HU, Schold JD, Kaplan B. Long-term renal allograft survival: Have we made significant progress or is it time to rethink our analytic and therapeutic strategies? Am J Transplant 2004 4 : 1289 1295.
    • (2004) Am J Transplant , vol.4 , pp. 1289-1295
    • Meier-Kriesche, H.U.1    Schold, J.D.2    Kaplan, B.3
  • 6
    • 34547850861 scopus 로고    scopus 로고
    • Transplant glomerulopathy: Subclinical incidence and association with alloantibody
    • Gloor JM, Sethi S, Stegall MD et al. Transplant glomerulopathy: Subclinical incidence and association with alloantibody. Am J Transplant 2007 7 : 2124 2132.
    • (2007) Am J Transplant , vol.7 , pp. 2124-2132
    • Gloor, J.M.1    Sethi, S.2    Stegall, M.D.3
  • 7
    • 34547842740 scopus 로고    scopus 로고
    • Tacrolimus exposure and evolution of renal allograft histology in the first year after transplantation
    • Naesens M, Lerut E, Damme BV, Vanrenterghem Y, Kuypers DRJ. Tacrolimus exposure and evolution of renal allograft histology in the first year after transplantation. Am J Transplant 2007 7 : 2114 2123.
    • (2007) Am J Transplant , vol.7 , pp. 2114-2123
    • Naesens, M.1    Lerut, E.2    Damme, B.V.3    Vanrenterghem, Y.4    Kuypers, D.R.J.5
  • 8
    • 10744220677 scopus 로고    scopus 로고
    • ®)/ sirolimus in renal transplantation. I. Drug interactions and rejection at one year
    • ®)/sirolimus in renal transplantation. I. Drug interactions and rejection at one year. Transplantation 2004 77 : 244 251.
    • (2004) Transplantation , vol.77 , pp. 244-251
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3
  • 9
    • 10744225688 scopus 로고    scopus 로고
    • ®)/ sirolimus in renal transplantation. II. Survival, function, and protocol compliance at one year
    • ®)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at one year. Transplantation 2004 77 : 252 258.
    • (2004) Transplantation , vol.77 , pp. 252-258
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3
  • 10
    • 0035870592 scopus 로고    scopus 로고
    • Six year clinical effect of donor bone marrow infusions in renal transplant patients
    • Ciancio G, Miller J, Garcia-Morales RO et al. Six year clinical effect of donor bone marrow infusions in renal transplant patients. Transplantation 2001 71 : 827 835.
    • (2001) Transplantation , vol.71 , pp. 827-835
    • Ciancio, G.1    Miller, J.2    Garcia-Morales, R.O.3
  • 11
    • 0032852141 scopus 로고    scopus 로고
    • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
    • Spitzer TR, Delmonico F, Tolkoff-Rubin N et al. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation 1999 68 : 480 484.
    • (1999) Transplantation , vol.68 , pp. 480-484
    • Spitzer, T.R.1    Delmonico, F.2    Tolkoff-Rubin, N.3
  • 13
    • 0033610681 scopus 로고    scopus 로고
    • Alemtuzumab 1H allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients
    • Calne R, Moffatt SD, Friend PJ et al. Alemtuzumab 1H allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients. Transplantation 1999 68 : 613 616.
    • (1999) Transplantation , vol.68 , pp. 613-616
    • Calne, R.1    Moffatt, S.D.2    Friend, P.J.3
  • 14
    • 0034501632 scopus 로고    scopus 로고
    • Alemtuzumab monoclonal antibody therapy
    • Flynn JM, Byrd JC. Alemtuzumab monoclonal antibody therapy. Curr Opin Oncol 2000 12 : 574 581.
    • (2000) Curr Opin Oncol , vol.12 , pp. 574-581
    • Flynn, J.M.1    Byrd, J.C.2
  • 15
    • 20544458513 scopus 로고    scopus 로고
    • Alemtuzumab (Alemtuzumab 1H) induction therapy in cadaveric kidney transplantation - Efficacy and safety at five years
    • Watson CJE, Bradley JA, Friend PJ et al. Alemtuzumab (Alemtuzumab 1H) induction therapy in cadaveric kidney transplantation - efficacy and safety at five years. Am J Transplant 2005 5 : 1347 1353.
    • (2005) Am J Transplant , vol.5 , pp. 1347-1353
    • Watson, C.J.E.1    Bradley, J.A.2    Friend, P.J.3
  • 16
    • 0038638396 scopus 로고    scopus 로고
    • Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Alemtuzumab)
    • Kirk AD, Hale DA, Mannon RB et al. Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Alemtuzumab). Transplantation 2003 76 : 120 129.
    • (2003) Transplantation , vol.76 , pp. 120-129
    • Kirk, A.D.1    Hale, D.A.2    Mannon, R.B.3
  • 17
    • 33745279073 scopus 로고    scopus 로고
    • Autoimmune thyroid disease after renal transplantation using depletional induction with Alemtuzumab
    • Kirk AD, Hale DA, Swanson SJ, Mannon RB. Autoimmune thyroid disease after renal transplantation using depletional induction with Alemtuzumab. Am J Transplant 2006 6 : 1084 1085.
    • (2006) Am J Transplant , vol.6 , pp. 1084-1085
    • Kirk, A.D.1    Hale, D.A.2    Swanson, S.J.3    Mannon, R.B.4
  • 18
    • 0033552391 scopus 로고    scopus 로고
    • Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis
    • Coles AJ, Wing M, Smith S et al. Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Lancet 1999 354 : 1691 1695.
    • (1999) Lancet , vol.354 , pp. 1691-1695
    • Coles, A.J.1    Wing, M.2    Smith, S.3
  • 19
    • 27744481221 scopus 로고    scopus 로고
    • Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxypergualin
    • Kirk AD, Mannon RB, Kleiner DE et al. Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxypergualin. Transplantation 2005 80 : 1051 1059.
    • (2005) Transplantation , vol.80 , pp. 1051-1059
    • Kirk, A.D.1    Mannon, R.B.2    Kleiner, D.E.3
  • 20
    • 0033572898 scopus 로고    scopus 로고
    • Peritransplant tolerance induction in macaques: Early events reflecting the unique synergy between immunotoxin and deoxyspergualin
    • Thomas JM, Contreras JL, Jiang XL. Peritransplant tolerance induction in macaques: Early events reflecting the unique synergy between immunotoxin and deoxyspergualin. Transplantation 1999 68 : 1660.
    • (1999) Transplantation , vol.68 , pp. 1660
    • Thomas, J.M.1    Contreras, J.L.2    Jiang, X.L.3
  • 22
    • 0038805159 scopus 로고    scopus 로고
    • Alemtuzumab induction plus rapamycin monotherapy for renal transplantation: Results of a pilot study
    • Knechtle SJ, Pirsch JD, Fechner J Jr. et al. Alemtuzumab induction plus rapamycin monotherapy for renal transplantation: Results of a pilot study. Am J Transplant 2003 3 : 722 730.
    • (2003) Am J Transplant , vol.3 , pp. 722-730
    • Knechtle, S.J.1    Pirsch, J.D.2    Fechner Jr., J.3
  • 23
    • 33749444584 scopus 로고    scopus 로고
    • Outcomes at 3 years of prospective pilot study of Alemtuzumab and sirolimus immunosuppression for renal transplantation
    • Barth RN, Janus CA, Lillesand CA et al. Outcomes at 3 years of prospective pilot study of Alemtuzumab and sirolimus immunosuppression for renal transplantation. Transplant Int 2006 19 : 885 892.
    • (2006) Transplant Int , vol.19 , pp. 885-892
    • Barth, R.N.1    Janus, C.A.2    Lillesand, C.A.3
  • 24
    • 33644833287 scopus 로고    scopus 로고
    • Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression
    • Flechner SM, Friend PJ, Brockmann J et al. Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression. Am J Transplant 2005 5 : 3009 3014.
    • (2005) Am J Transplant , vol.5 , pp. 3009-3014
    • Flechner, S.M.1    Friend, P.J.2    Brockmann, J.3
  • 25
    • 18644376332 scopus 로고    scopus 로고
    • Calcineurin inhibitor and steroid-free immunosuppression in pancreas-kidney and solitary pancreas transplantation
    • Gruessner RWG, Kandaswamy R, Humar A, Gruessner AC, Sutherland DER. Calcineurin inhibitor and steroid-free immunosuppression in pancreas-kidney and solitary pancreas transplantation. Transplantation 2005 79 : 1184 1189.
    • (2005) Transplantation , vol.79 , pp. 1184-1189
    • Gruessner, R.W.G.1    Kandaswamy, R.2    Humar, A.3    Gruessner, A.C.4    Sutherland, D.E.R.5
  • 26
    • 4744354630 scopus 로고    scopus 로고
    • Alemtuzumab in renal transplantation: The University of Wisconsin experience
    • Knechtle SJ, Fernandez LA, Pirsch JD et al. Alemtuzumab in renal transplantation: The University of Wisconsin experience. Surgery 2004 136 : 754 760.
    • (2004) Surgery , vol.136 , pp. 754-760
    • Knechtle, S.J.1    Fernandez, L.A.2    Pirsch, J.D.3
  • 27
    • 20144389244 scopus 로고    scopus 로고
    • Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with thymoglobulin or Alemtuzumab
    • Shapiro R, Basu A, Tzan H et al. Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with thymoglobulin or Alemtuzumab. J Am Coll Surg 2005 200 : 505 515.
    • (2005) J Am Coll Surg , vol.200 , pp. 505-515
    • Shapiro, R.1    Basu, A.2    Tzan, H.3
  • 28
    • 33748477306 scopus 로고    scopus 로고
    • Living donor renal transplantation using Alemtuzumab induction and tacrolimus monotherapy
    • Tan HP, Kaczorowski DJ, Basu M et al. Living donor renal transplantation using Alemtuzumab induction and tacrolimus monotherapy. Am J Transplant 2006 6 : 2409 2417.
    • (2006) Am J Transplant , vol.6 , pp. 2409-2417
    • Tan, H.P.1    Kaczorowski, D.J.2    Basu, M.3
  • 29
    • 4143138695 scopus 로고    scopus 로고
    • The use of Alemtuzumab as induction therapy in renal transplantation: Preliminary results
    • Ciancio G, Burke GW, Gaynor JJ et al. The use of Alemtuzumab as induction therapy in renal transplantation: Preliminary results. Transplantation 2004 78 : 426 433.
    • (2004) Transplantation , vol.78 , pp. 426-433
    • Ciancio, G.1    Burke, G.W.2    Gaynor, J.J.3
  • 30
    • 36849019628 scopus 로고    scopus 로고
    • The use of Alemtuzumab as induction therapy to achieve steroid avoidance in African-American and Hispanic first renal transplant recipients [abstract]
    • Ciancio G, Sageshima J, Gaynor JJ et al. The use of Alemtuzumab as induction therapy to achieve steroid avoidance in African-American and Hispanic first renal transplant recipients [abstract]. Am J Transplant 2006 1324 : 513.
    • (2006) Am J Transplant , vol.1324 , pp. 513
    • Ciancio, G.1    Sageshima, J.2    Gaynor, J.J.3
  • 31
    • 34250658405 scopus 로고    scopus 로고
    • Alemtuzumab (Alemtuzumab 1H) induction with tacrolimus monotherapy is safe for high immunological risk renal transplantation
    • Thomas PG, Woodside KJ, Lappin JA, Vaidya S, Rajaraman S, Gugliuzza KK. Alemtuzumab (Alemtuzumab 1H) induction with tacrolimus monotherapy is safe for high immunological risk renal transplantation. Transplantation 2007 83 : 1509 1512.
    • (2007) Transplantation , vol.83 , pp. 1509-1512
    • Thomas, P.G.1    Woodside, K.J.2    Lappin, J.A.3    Vaidya, S.4    Rajaraman, S.5    Gugliuzza, K.K.6
  • 32
    • 26644457880 scopus 로고    scopus 로고
    • Randomized trial of Alemtuzumab for prevention of graft rejection and preservation of renal function after kidney transplantation
    • Vathsala A, Ona ET, Tan SY et al. Randomized trial of Alemtuzumab for prevention of graft rejection and preservation of renal function after kidney transplantation. Transplantation 2005 80 : 765 774.
    • (2005) Transplantation , vol.80 , pp. 765-774
    • Vathsala, A.1    Ona, E.T.2    Tan, S.Y.3
  • 33
    • 23944434883 scopus 로고    scopus 로고
    • A randomized trial of three renal transplant induction antibodies: Early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring
    • Ciancio G, Burke G, Gaynor JJ et al. A randomized trial of three renal transplant induction antibodies: Early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring. Transplantation 2005 80 : 457 465.
    • (2005) Transplantation , vol.80 , pp. 457-465
    • Ciancio, G.1    Burke, G.2    Gaynor, J.J.3
  • 34
    • 33644676984 scopus 로고    scopus 로고
    • Alemtuzumab induction and prednisone-free maintenance immunotherapy in kidney transplantation: Comparison with basiliximab induction - Long-term results
    • Kaufman DB, Leventhal JR, Axelrod D et al. Alemtuzumab induction and prednisone-free maintenance immunotherapy in kidney transplantation: Comparison with basiliximab induction - long-term results. Am J Transplant 2005 5 : 2539 2548.
    • (2005) Am J Transplant , vol.5 , pp. 2539-2548
    • Kaufman, D.B.1    Leventhal, J.R.2    Axelrod, D.3
  • 35
    • 33644882722 scopus 로고    scopus 로고
    • Alemtuzumab induction and prednisone-free maintenance immunotherapy in simultaneous pancreas-kidney transplantation comparison with rabbit antithymocyte globulin induction - Long-term results
    • Kaufman DB, Leventhal JR, Gallon LG, Parker MA. Alemtuzumab induction and prednisone-free maintenance immunotherapy in simultaneous pancreas-kidney transplantation comparison with rabbit antithymocyte globulin induction - long-term results. Am J Transplant 2006 6 : 331 339.
    • (2006) Am J Transplant , vol.6 , pp. 331-339
    • Kaufman, D.B.1    Leventhal, J.R.2    Gallon, L.G.3    Parker, M.A.4
  • 37
    • 33846150015 scopus 로고    scopus 로고
    • Opportunistic infections in 547 organ transplant recipients receiving Alemtuzumab, a humanized monoclonal CD-52 antibody
    • Peleg AY, Husain S, Kwak EJ et al. Opportunistic infections in 547 organ transplant recipients receiving Alemtuzumab, a humanized monoclonal CD-52 antibody. Clin Infect Dis 2007 44 : 204 212.
    • (2007) Clin Infect Dis , vol.44 , pp. 204-212
    • Peleg, A.Y.1    Husain, S.2    Kwak, E.J.3
  • 38
    • 20044380331 scopus 로고    scopus 로고
    • Immunocompetent T-cells with memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion
    • Pearl JP, Parris J, Hale DA et al. Immunocompetent T-cells with memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. Am J Transplant 2005 5 : 465 474.
    • (2005) Am J Transplant , vol.5 , pp. 465-474
    • Pearl, J.P.1    Parris, J.2    Hale, D.A.3
  • 39
    • 26444609695 scopus 로고    scopus 로고
    • Severe early acute humoral rejection resulting in allograft loss in renal transplant recipient with Alemtuzumab induction therapy
    • Hill P, Galiardini E, Ruggenenti P, Remuzzi G. Severe early acute humoral rejection resulting in allograft loss in renal transplant recipient with Alemtuzumab induction therapy. Nephrol Dial Transplant 2005 : 1741 1744.
    • (2005) Nephrol Dial Transplant , pp. 1741-1744
    • Hill, P.1    Galiardini, E.2    Ruggenenti, P.3    Remuzzi, G.4
  • 40
    • 33947249410 scopus 로고    scopus 로고
    • Regulatory T cells and T cell depletion: Role of immunosuppressive drugs
    • Noris M, Casiraghi F, Todeschini M et al. Regulatory T cells and T cell depletion: Role of immunosuppressive drugs. J Am Soc Nephrol 2007 18 : 1007 1018.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1007-1018
    • Noris, M.1    Casiraghi, F.2    Todeschini, M.3
  • 41
    • 34248679904 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in transplantation: Progress, challenges and prospects
    • Kang SM, Tang Q, Bluestone JA. CD4+CD25+ regulatory T cells in transplantation: Progress, challenges and prospects. Am J Transplant 2007 7 : 1457 1463.
    • (2007) Am J Transplant , vol.7 , pp. 1457-1463
    • Kang, S.M.1    Tang, Q.2    Bluestone, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.