메뉴 건너뛰기




Volumn 63, Issue 1, 1998, Pages 48-53

The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; PREDNISONE; RAPAMYCIN;

EID: 13144256680     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(98)90120-5     Document Type: Article
Times cited : (121)

References (18)
  • 1
    • 0016724057 scopus 로고
    • Rapamycin (ay-22,989), a new antifungal antibiotic; I: Taxonomy of the producing streptomycete and isolation of the active principle
    • Tokyo
    • Vezina C, Kudelski A, Sehgal SN. Rapamycin (ay-22,989), a new antifungal antibiotic; I: Taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 1975;28:721-6.
    • (1975) J Antibiot , vol.28 , pp. 721-726
    • Vezina, C.1    Kudelski, A.2    Sehgal, S.N.3
  • 2
    • 0016713286 scopus 로고
    • Rapamycin (ay-22,989), a new antifungal antibiotic; II: Fermentation, isolation and characterization
    • Tokyo
    • Sehgal SN, Baker H, Vezina C. Rapamycin (ay-22,989), a new antifungal antibiotic; II: Fermentation, isolation and characterization. J Antibiot (Tokyo) 1975;28:727-32.
    • (1975) J Antibiot , vol.28 , pp. 727-732
    • Sehgal, S.N.1    Baker, H.2    Vezina, C.3
  • 3
    • 0030064388 scopus 로고    scopus 로고
    • The side effect profile of rapamycin: A phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients
    • Murgia MG, Jordan S, Kahan BD. The side effect profile of rapamycin: a phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients. Kidney Int 1996;49:209-16.
    • (1996) Kidney Int , vol.49 , pp. 209-216
    • Murgia, M.G.1    Jordan, S.2    Kahan, B.D.3
  • 4
    • 0031008434 scopus 로고    scopus 로고
    • The pharmacokinetics of rapamycin in stable renal transplant patients after multiple oral dose administration
    • Zimmerman J, Kahan BD. The pharmacokinetics of rapamycin in stable renal transplant patients after multiple oral dose administration. J Clin Pharmacol 1997;37:405-15.
    • (1997) J Clin Pharmacol , vol.37 , pp. 405-415
    • Zimmerman, J.1    Kahan, B.D.2
  • 5
    • 0027446611 scopus 로고
    • The relationship of blood concentrations of rapamycin and cyclosporine to suppression of allograft rejection in a rabbit heterotopic heart transplant model
    • Fryer J, Yatscoff RW, Pascoe EA, Thliveris J. The relationship of blood concentrations of rapamycin and cyclosporine to suppression of allograft rejection in a rabbit heterotopic heart transplant model. Transplantation 1993;55:340-5.
    • (1993) Transplantation , vol.55 , pp. 340-345
    • Fryer, J.1    Yatscoff, R.W.2    Pascoe, E.A.3    Thliveris, J.4
  • 8
    • 0026662551 scopus 로고
    • Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat
    • Sattler M, Guengerich FP, Yun CH, Christians U, Sewing KF. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab Dispos 1992;20: 753-61.
    • (1992) Drug Metab Dispos , vol.20 , pp. 753-761
    • Sattler, M.1    Guengerich, F.P.2    Yun, C.H.3    Christians, U.4    Sewing, K.F.5
  • 9
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and time distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity on cancer chemotherapy
    • Wacher VJ, Wu CY, Benet LZ. Overlapping substrate specificities and time distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity on cancer chemotherapy. Mol Carcinog 1995;13:129-34.
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 11
    • 0028820208 scopus 로고
    • Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
    • Wu CY, Benet LZ, Hebert MF, Gupta SK, Rowland M, Gomex DY, et al. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther 1995; 58:492-7.
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 492-497
    • Wu, C.Y.1    Benet, L.Z.2    Hebert, M.F.3    Gupta, S.K.4    Rowland, M.5    Gomex, D.Y.6
  • 12
    • 0028219564 scopus 로고
    • Sample clean-up and high-performance liquid Chromatographic techniques for measurement of whole blood rapamycin concentrations
    • Napoli KL, Kahan BD. Sample clean-up and high-performance liquid Chromatographic techniques for measurement of whole blood rapamycin concentrations. J Chromatogr B Biomed Appl 1994;654:111-20.
    • (1994) J Chromatogr B Biomed Appl , vol.654 , pp. 111-120
    • Napoli, K.L.1    Kahan, B.D.2
  • 13
    • 0029829769 scopus 로고    scopus 로고
    • Routine clinical monitoring of rapamycin (rapamycin) whole-blood concentrations by HPLC with ultraviolet detection
    • Napoli KL, Kahan BD. Routine clinical monitoring of rapamycin (rapamycin) whole-blood concentrations by HPLC with ultraviolet detection. Clin Chem 1996; 42:1944-8.
    • (1996) Clin Chem , vol.42 , pp. 1944-1948
    • Napoli, K.L.1    Kahan, B.D.2
  • 14
    • 0027226147 scopus 로고
    • Influence of cyclosporine pharmacokinetics, trough concentrations, and AUC monitoring on outcome after kidney transplant
    • Lindholm A, Kahan BD. Influence of cyclosporine pharmacokinetics, trough concentrations, and AUC monitoring on outcome after kidney transplant. Clin Pharmacol Ther 1993;54:205-18.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 205-218
    • Lindholm, A.1    Kahan, B.D.2
  • 17
    • 0027528920 scopus 로고
    • Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine
    • Takeguchi N, Koike M, Matsui W, Kashiwagura T, Kawahara K. Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine. Transplantation 1993; 55:646-50.
    • (1993) Transplantation , vol.55 , pp. 646-650
    • Takeguchi, N.1    Koike, M.2    Matsui, W.3    Kashiwagura, T.4    Kawahara, K.5
  • 18
    • 0028304606 scopus 로고
    • Within-day consistency in cyclosporine pharmacokinetics from a microemulsion formulation in renal transplant patients
    • Kovarik JM, Mueller EA, van Bree JB, Arns W, Renner E, Kutz K. Within-day consistency in cyclosporine pharmacokinetics from a microemulsion formulation in renal transplant patients. Ther Drug Monit 1994;16:232-7.
    • (1994) Ther Drug Monit , vol.16 , pp. 232-237
    • Kovarik, J.M.1    Mueller, E.A.2    Van Bree, J.B.3    Arns, W.4    Renner, E.5    Kutz, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.