Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression

Chemico-Biological Interactions

Volumn 185, Issue 1, 2010, Pages 18-24

  Lee, Eun Jung ^a   Kim, So Young ^a   Hyun, Jin Won ^c   Min, Sung Won ^d   Kim, Dong Hyun ^d   Kim, Hee Sun ^a,b  

^a Ewha Womans University School of Medicine   (South Korea)

^b Ewha Womans University   (South Korea)

^c Jeju National University School of Medicine   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

Gene regulation; Glioma; Glycitein; Invasion; MMP 3; MMP 9

Indexed keywords

DNA; GELATINASE B; GLYCITEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; STROMELYSIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; ASTROCYTOMA; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROMOTER REGION; PROTEIN DNA BINDING;

ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; DNA; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; ISOFLAVONES; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; NEUROGLIA; NF-KAPPA B; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTOR AP-1;

BACTERIA (MICROORGANISMS);

EID: 77950923898     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.02.037     Document Type: Article

References (35)

1. Bello L., Giussani C., Carrabba G., Pluderi M., Costa F., Bikfalvi A. Angiogenesis and invasion in gliomas. Cancer Treat. Res. 2004, 117:263-284.
2. Rao J.S. Molecular mechanisms of glioma invasiveness: the role of proteases. Nat. Rev. Cancer 2003, 3:489-501.
3. Shapiro W.R., Shapiro J.R. Biology and treatment of malignant glioma. Oncology 1998, 12:233-240.
4. Binder D.K., Berger M.S. Proteases and the biology of glioma invasion. J. Neurooncol. 2002, 56:149-158.
5. Rao J.S., Steck S.P.A., Tofilon P., Boyd D., Ali-Osman F., Stelter-Stevenson W.G., Liotta L.A., Sawaya R. Role of plasminogen activator and of 92-kD type IV collagenase in glioblastoma invasion using an in vitro matrigel model. J. Neurosurg. 1994, 18:129-138.
6. Sawaya R.E., Yamamoto M., Gokaslan Z.L., Wang S.W., Mohanam S., Fuller G.N., McCutcheon I.E., Stetler-Stevenson W.G., Nicolson G.L., Rao J.S. Expression and localization of 72kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo. Clin. Exp. Metastasis 1996, 14:35-42.
7. McCready J., Broaddus W.C., Sykes V., Fillmore H.L. Association of a single nucleotide polymorphism in the matrix metalloproteinase-1 promoter with glioblastoma. Int. J. Cancer 2005, 117:781-785.
8. Bodey B., Bodey B., Siegel S.E., Kaiser H.E. Matrix metalloproteinase expression in childhood astrocytomas. Anticancer Res. 2000, 20:3287-3292.
9. Johansson N., Ahonen M., Kahari V.M. Matrix metalloproteinases in tumor invasion. Cell Mol. Life Sci. 2000, 57:5-15.
10. Ramos-DeSimone N., Hahn-Dantona E., Sipley J., Nagase H., French D.L., Quigley J.P. Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. J. Biol. Chem. 1999, 274:13066-13076.
11. Park H.J., Park J.H., Moon J.O., Lee K.T., Jung W.T., Oh S.R., Lee H.K. Isoflavone glycosides from the flowers of Pueraria thunbergiana. Phytochemistry 1999, 51:147-151.
12. Yamaki K., Kim D.H., Ryu N., Kim Y.P., Shin K.H., Ohuchi K. Effects of naturally occurring isoflavones on prostaglandin E2 production. Planta Med. 2002, 68:97-100.
13. Li X., Li J.F., Wang D., Wang W.N., Cui Z. Isoflavone glycosides from the bark of Maackia amurensis. Yao Xue Xue Bao 2009, 44:63-68.
14. Klejdus B., Mikelová R., Petrlová J., Potesil D., Adam V., Stiborová M., Hodek P., Vacek J., Kizek R., Kubán V. Determination of isoflavones in soy bits by fast column high-performance liquid chromatography coupled with UV-visible diode-array detection. J. Chromatogr. A 2005, 1084:71-79.
15. Heinonen S.M., Hoikkala A., Wahala K., Adlercreutz H. Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton. J. Steroid Biochem. Mol. Biol. 2003, 87:285-299.
16. Sepehr E., Cooke G., Robertson P., Gilani G.S. Bioavailability of soy isoflavones in rats. Part I: Application of accurate methodology for studying the effects of gender and source of isoflavones. Mol. Nutr. Food Res. 2007, 51:799-812.
17. Song T.T., Hendrich S., Murphy P.A. Estrogenic activity of glycitein, a soy isoflavone. J. Agric. Food Chem. 2002, 50:2470-2474.
18. Anthony M.S., Clarkson T.B., Williams J.K. Effects of soy isoflavones on atherosclerosis: potential mechanisms. Am. J. Clin. Nutr. 1998, 68:1390S-1393S.
19. Kang K.A., Zhang R., Piao M.J., Lee K.H., Kim B.J., Kim S.Y., Kim H.S., Kim D.H., You H.J., Hyun J.W. Inhibitory effects of glycitein on hydrogen peroxide induced cell damage by scavenging reactive oxygen species and inhibiting c-Jun N-terminal kinase. Free Radic. Res. 2007, 41:720-729.
20. Gutierrez-Zepeda A., Santell R., Wu Z., Brown M., Wu Y., Khan I., Link C.D., Zhao B., Luo Y. Soy isoflavone glycitein protects against beta-amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci. 2005, 6:54-62.
21. Park J.S., Woo M.S., Kim D.H., Hyun J.W., Kim W.K., Lee J.C., Kim H.S. Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. J. Pharmacol. Exp. Ther. 2007, 32:1237-1245.
22. Sheu F., Lai H.H., Yen G.C. Suppression effect of soy isoflavones on nitric oxide production in Raw 264.7 macrophages. J. Agric. Food Chem. 2001, 49:1767-1772.
23. Magee P.J., McGlynn H., Rowland I.R. Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro. Cancer Lett. 2004, 208:35-41.
24. Kim M.H., Gutierrez A.M., Goldfarb R.H. Different mechanisms of soy isoflavones in cell cycle regulation and inhibition of invasion. Anticancer Res. 2002, 22:3811-3817.
25. Jung S.H., Woo M.S., Kim S.Y., Kim W.K., Hyun J.W., Kim E.J., Kim D.H., Kim H.S. Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells. Int. J. Cancer 2006, 118:490-497.
26. Woo M.S., Jung S.H., Kim S.Y., Hyun J.W., Ko K.H., Kim W.K., Kim H.S. Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells. Biochem. Biophys. Res. Commun. 2005, 335:1017-1025.
27. Kim S.Y., Jung S.H., Kim H.S. Curcumin is a potent broad spectrum inhibitor of matrix metalloproteinase gene expression in human astroglioma cells. Biochem. Biophys. Res. Commun. 2005, 337:510-516.
28. Kim S.Y., Lee E.J., Woo M.S., Jung J.S., Hyun J.W., Min S.W., Kim D.H., Kim H.S. Inhibition of matrix metalloproteinase-9 gene expression by an isoflavone metabolite, irisolidone in U87MG human astroglioma cells. Biochem. Biophys. Res. Commun. 2008, 337:510-516.
29. Vincenti M.P., Brinckerhoff C.E. Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?. J. Cell. Physiol. 2007, 213:355-364.
30. Clark I.M., Swingler T.E., Sampieri C.L., Edwards D.R. The regulation of matrix metalloproteinases and their inhibitors. Int. J. Biochem. Cell Biol. 2008, 40:1362-1378.
31. Kim K.S., Kim H.Y., Joe E.H., Jou I. Matrix metalloproteinase-3 induction in rat brain astrocytes: focus on the role of two AP-1 elements. Biochem. J. 2008, 410:605-611.
32. Yakisich J.S., Ohlsson Lindblom I., Siden A., Cruz M.H. Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein. Oncol. Rep. 2009, 22:569-574.
33. Schmidt F., Knobbe C.B., Frank B., Wolburg H., Weller M. The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines. Oncol. Rep. 2008, 19:1061-1066.
34. Siegelin M.D., Gaiser T., Habel A., Siegelin Y. Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2. Neurosci. Lett. 2009, 454:223-228.
35. Puli S., Lai J.C., Bhushan A. Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. J. Neurooncol. 2006, 79:135-142.