Different mechanisms of soy isoflavones in cell cycle regulation and inhibition of invasion

Anticancer Research

Volumn 22, Issue 6 C, 2002, Pages 3811-3817

  Kim, Myoung H ^a   Gutierrez, Angelica M ^b   Goldfarb, Ronald H ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b TEXAS A AND M UNIVERSITY CORPUS CHRISTI   (United States)

Author keywords

Cell cycle; Invasion; Matrix metalloproteinases; Soy isoflavones

Indexed keywords

CAFFEINE; COLLAGENASE 3; DAIDZEIN; GENISTEIN; GLYCITEIN; ISOFLAVONE; NEUTROPHIL COLLAGENASE; SOYBEAN PROTEIN;

ARTICLE; CANCER PREVENTION; CELL CYCLE; CELL CYCLE G2 PHASE; CELL INVASION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SOYBEAN;

3T3 CELLS; ANIMALS; ANTICARCINOGENIC AGENTS; CAFFEINE; CELL CYCLE; COLLAGENASES; GENISTEIN; HUMANS; ISOFLAVONES; JURKAT CELLS; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 8; MICE; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES;

EID: 0036875215     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Akiyama T, Ishida J, Nakagawa S, Ogawara, H, Watanabe S, Itoh N, Shibuya M and Fukami Y: Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595, 1987.
2. Anderson JW, Johnstone BM and Cook-Newell ME: Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med 333: 276-282, 1995.
3. Arjmandi BH, Alekel L, Hollis BW, Amin D, Stacewicz-Sapuntzakis M, Guo P and Kukreja SC: Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis. J Nutr 126: 161-167, 1996.
4. Barnes S and Peterson TG: Biochemical targets of the isoflavone genistein in tumor cell lines. Proc Soc Exp Biol Med 208: 103-108, 1995.
5. Barnes S, Peterson TG and Coward L: Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer. J Cell Biochem Suppl 22: 181-187, 1995.
6. Bearz A, Tell G, Fon-nisano S, Merluzzi S, Colombatti A and Pucillo C: Adhesion to fibronectin promotes the activation of the p125(FAK)/Zap-70complex in human T cells. Immunology 98: 564-568, 1999.
7. Bergan RC, Waggle DH, Carter SK, Horak I, Slicheninyer W and Meyers M: Tyrosine kinase inhibitors and signal transduction modulators: Rationale and current status as chemopreventive agents for prostate cancer. Urology 57: 77-80, 2001.
8. Bulavin DV, Amundson SA and Fomace AJ: p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony. Curr Opin Genet Dev 12: 92-97, 2002.
9. Chan DW, Son SC, Block W, Ye R, Khanna KK, Wold MS, Douglas P, Goodarzi AA, Pelley J, Taya Y, Lavin MF and Lees-Miller SP: Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase. J Biol Chem 275: 7803-7810, 2000.
10. Constantinou A, Kiguchi K and Huberman E: Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res 50: 2618-2624, 1990.
11. Darbon JM, Penary M, Escalas N, Casagrande F, Goubin-Gramatica F, Baudouin C and Ducommun B: Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells. J Biol Chem 275: 15363-15369, 2000.
12. Darzynkiewicz Z, Bedner E and Li X: Analysis of cell death by flow and laser-scanning cytometry. In: Apoptosis (Studzinski GP, ed). New York, Oxford University Press. 1999, pp 57-80.
13. Davis JN, Singh B, Bhuiyan M and Sarkar FH: Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells. Nutr Cancer 32: 123-131, 1998.
14. Giancotti FG and Ruoslahti E: Integrin signaling. Science 285(5430): 1028-1032, 1999.
15. Hollenberg MD: Tyrosine kinase-mediated signal transduction pathways and the actions of polypeptide growth factors and G-protein-coupled agonists in smooth muscle. Mol Cell Biochem 149-150: 77-85, 1995.
16. Kennedy AR: The evidence for soybean products as cancer preventive agents. J Nutr 125(3 Suppl): 733S-743S, 1995.
17. Kim H, Peterson TG and Barnes S: Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways. Am J Clin Nutr 68(6 Suppl): 1418S-1425S, 1998.
18. Kim MH, Albertsson P, Xue Y, Nanninark U, Kitson RP and Goldfarb RH: Expression of neutrophil collagenase (MMP-8) in Jurkat T leukemia cells and its role in invasion. Anticancer Res 21: 45-50, 2001.
19. Li Y, Bhuiyan M and Sarkar FH: Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by genistein. Int J Oncol 15: 525-533, 1999.
20. Lian F, Bhuiyan M, Li YW, Wall N, Kraut M and Sarkar FH: Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line. Nutr Cancer 31: 184-191, 1998.
21. Lian F, Li Y, Bhuiyan M and Sarkar FH: p53-independent apoptosis induced by genistein in lung cancer cells. Nutr Cancer 33: 125-131, 1999.
22. Markovits J, Linassier C, Fosse P, Couprie J, Pierre J, Jacquemin-Sablon A, Saucier JM, Le Pecq JB and Larsen AK: Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II. Cancer Res 49: 5111-5117, 1989.
23. Melchiori A, Albini A, Ray JM and Stetler-Stevenson WG: Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res 52: 2353-2356, 1992.
24. Messina MJ, Persky V, Setchell KD and Barnes S: Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer 21: 113-131, 1994.
25. Murkies AL, Lombard C, Strauss BJ, Wilcox G, Burger HG and Morton MS: Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat. Maturitas 21: 189-195, 1995.
26. Nelson AR, Fingleton B, Rothenberg ML and Matrisian LM: Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol 18: 1135-1149, 2000.
27. Pan W, Ikeda K, Takebe M and Yamori Y: Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats. J Nutr 131: 1154-1158, 2001.
28. Porter AC and Vaillancourt RR: Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis. Oncogene 17 (11 Reviews): 1343-1352, 1998.
29. Robinson MJ, Corbett AH and Osheroff N: Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II. Biochemistry 32: 3638-3643, 1993.
30. Sargeant P, Famdale RW and Sage SO: ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem 268: 18151-18156, 1993.
31. Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, Karnitz LM and Abraham RT: Inhibition of ATM and ATR kinase activities by the radio sensitizing agent, caffeine. Cancer Res 59: 4375-4382, 1999.
32. Shao, ZM, Alpaugh ML, Fontana JA and Barsky SH: Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis. J Cell Biochem 69: 44-54, 1998.
33. Shao ZM, Wu J, Shen ZZ and Barsky SH: Genistein exerts multiple suppressive effects on human breast carcinoma cells. Cancer Res 58: 4851-4857, 1998.
34. Shao ZM, Wu J, Shen ZZ and Barsky SH: Genistein inhibits both constitutive and EGF-stimulated invasion in ER-negative human breast carcinoma cell lines. Anticancer Res 18: 1435-1439, 1998.
35. Song T, Bairua K, Buseman G and Murphy PA: Soy isoflavone analysis: quality control and a new internal standard. Am J Clin Nutr 68(6 Suppl): 1474S-1479S, 1998.
36. Spinozzi F, Pagliacci MC, Migliorati G, Moraca R, Grignani F, Riccardi C and Nicoletti I: The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. Leuk Res 18: 431-439, 1994.
37. Traganos F, Ardelt B, Halko N, Bruno S and Darzynkiewicz Z: Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. Cancer Res 52: 6200-6208, 1992.
38. Wang H-J and Murphy PA: Isoflavone composition of American and Japanese soybean in Iowa: effects of variety, crop year, and location. J Agric Food Chem 42: 1674-1677, 1994.
39. Westermarck J and Kahari VM: Regulation of matrix metalloproteinase expression in tumor invasion. Faseb J 13: 781-792, 1999.
40. Ye R, Bodero A, Zhou BB, Khanna KK, Lavin MF and Lees-Miller SP: The plant isoflavenoid, genistein, activates p53 and Chk2 in an ATM-dependent manner. J Biol Chem 276: 4828-4833, 2001.
41. Yoshida H, Teramoto T, Ikeda K and Yamori Y: Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem 65: 1211-1213, 2001.
42. Yu M, Bowden ET, Sitlani J, Sato H, Seiki M, Mueller SC and Thompson EW: Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells. Cancer Res 57: 5028-5032, 1997.