Serum after traumatic brain injury increases proliferation and supports expression of osteoblast markers in muscle cells

Journal of Bone and Joint Surgery

Volumn 92, Issue 3, 2010, Pages 645-653

  Cadosch, Dieter ^a   Toffoli, Andrew M ^a   Gautschi, Oliver P ^a   Frey, Sönke P ^a   Zellweger, René ^b   Skirving, Allan P ^b   Filgueira, Luis ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; TRANSCRIPTION FACTOR OSTERIX; BIOLOGICAL MARKER; PARATHYROID HORMONE; PHOSPHATE;

ADULT; AGED; ARTICLE; CELL ASSAY; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CELL SUBPOPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FRACTURE; HETEROTOPIC OSSIFICATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; LONG BONE; MESENCHYME CELL; MUSCLE CELL; ORTHOPEDIC SURGERY; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING; ANALYSIS OF VARIANCE; BLOOD; BRAIN INJURY; COMPUTER ASSISTED TOMOGRAPHY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; FRACTURE HEALING; GLASGOW COMA SCALE; MALE; METABOLISM; PHYSIOLOGY; RADIOGRAPHY;

ADULT; ALKALINE PHOSPHATASE; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BRAIN INJURIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FRACTURE HEALING; FRACTURES, BONE; GLASGOW COMA SCALE; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; MUSCLE, SKELETAL; OSSIFICATION, HETEROTOPIC; OSTEOBLASTS; PARATHYROID HORMONE; PHENOTYPE; PHOSPHATES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77950881878     PISSN: 00219355     EISSN: 15351386     Source Type: Journal    
DOI: 10.2106/JBJS.I.00097     Document Type: Article

References (50)

1. Kaplan FS, Glaser DL, Hebela N, Shore EM. Heterotopic ossification. J Am Acad Orthop Surg. 2004;12:116-25.
2. Flin C, Curalucci H, Duvocelle A, Viton JM. [Heterotopic ossification and brain injury]. Ann Readapt Med Phys. 2002;45:517-20. French.
3. Garland DE, Blum CE, Waters RL. Periarticular heterotopic ossification in head-injured adults. Incidence and location. J Bone Joint Surg Am. 1980;62:1143-6.
4. Mendelson L, Grosswasser Z, Najenson T, Sandbank U, Solzi P. Periarticular new bone formation in patients suffering from severe head injuries. Scand J Rehabil Med. 1975;7:141-5.
5. Cope R. Heterotopic ossification. South Med J. 1990;83:1058-64.
6. Ekelund A, Brosjo O, Nilsson OS. Experimental induction of heterotopic bone. Clin Orthop Relat Res. 1991;263:102-12.
7. Garland DE. Clinical observations on fractures and heterotopic ossification in the spinal cord and traumatic brain injured populations. Clin Orthop Relat Res. 1988;233:86-101.
8. Sawyer JR, Myers MA, Rosier RN, Puzas JE. Heterotopic ossification: clinical and cellular aspects. Calcif Tissue Int. 1991;49:208-15.
9. Wharton GW, Morgan TH. Ankylosis in the paralyzed patient. J Bone Joint Surg Am. 1970;52:105-12.
10. Marusic A, Katavic V, Grcevic D, Lukic IK. Genetic variability of new bone induction in mice. Bone. 1999;25:25-32. (Pubitemid 29322057)
11. Bidner SM, Rubins IM, Desjardins JV, Zukor DJ, Goltzman D. Evidence for a humoral mechanism for enhanced osteogenesis after head injury. J Bone Joint Surg Am. 1990;72:1144-9. (Pubitemid 20343159)
12. Boes M, Kain M, Kakar S, Nicholls F, Cullinane D, Gerstenfeld L, Einhorn TA, Tornetta P 3rd. Osteogenic effects of traumatic brain injury on experimental fracture-healing. J Bone Joint Surg Am. 2006;88:738-43. Erratum in: J Bone Joint Surg Am. 2006;88:1602.
13. Cadosch D, Gautschi OP, Thyer M, Song S, Skirving AP, Filgueira L, Zellweger R. Humoral factors enhance fracture-healing and callus formation in patients with traumatic brain injury. J Bone Joint Surg Am. 2009;91:282-8. Erratum in: J Bone Joint Surg Am. 2009;91:938.
14. Gautschi OP, Cadosch D, Frey SP, Skirving AP, Filgueira L, Zellweger R. Serum-mediated osteogenic effect in traumatic brain-injured patients. ANZ J Surg. 2009;79:449-55.
15. Klein BY, Shohami E, Reikhinshtein Y, Ben-Bassat H, Liebergall M. Serum-mediated osteogenic effects of head injury on cultured rat marrow stromal cells. Calcif Tissue Int. 1999;65:217-22. (Pubitemid 29380342)
16. Kurer MH, Khoker MA, Dandona P. Human osteoblast stimulation by sera from paraplegic patients with heterotopic ossification. Paraplegia. 1992;30:165-8.
17. Musgrave DS, Bosch P, Lee JY, Pelinkovic D, Ghivizzani SC, Whalen J, Niyibizi C, Huard J. Ex vivo gene therapy to produce bone using different cell types. Clin Orthop Relat Res. 2000;378:290-305.
18. Okubo Y, Bessho K, Fujimura K, Konishi Y, Kusumoto K, Ogawa Y, Iizuka T. Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites. Int J Oral Maxillofac Surg. 2000;29:62-6.
19. Yoshida K, Bessho K, Fujimura K, Kusumoto K, Ogawa Y, Tani Y, Iizuka T. Osteoinduction capability of recombinant human bone morphogenetic protein-2 in intramuscular and subcutaneous sites: an experimental study. J Craniomaxillofac Surg. 1998;26:112-5.
20. Fujimura K, Bessho K, Kusumoto K, Konishi Y, Ogawa Y, Iizuka T. Experimental osteoinduction by recombinant human bone morphogeneticprotein 2 in tissue with low blood flow: a study in rats. Br J Oral Maxillofac Surg. 2001;39:294-300.
21. Alessandri G, Pagano S, Bez A, Benetti A, Pozzi S, Iannolo G, Baronio M, Invernici G, Caruso A, Muneretto C, Bisleri G, Parati E. Isolation and culture of human muscle-derived stem cells able to differentiate into myogenic and neurogenic cell lineages. Lancet. 2004;364:1872-83.
22. Williams JT, Southerland SS, Souza J, Calcutt AF, Cartledge RG. Cells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypes. Am Surg. 1999;65:22-6.
23. Mastrogiacomo M, Derubeis AR, Cancedda R. Bone and cartilage formation by skeletal muscle derived cells. J Cell Physiol. 2005;204:594-603.
24. Musgrave DS, Pruchnic R, Bosch P, Ziran BH, Whalen J, Huard J. Human skeletal muscle cells in ex vivo gene therapy to deliver bone morphogenetic protein-2. J Bone Joint Surg Br. 2002;84:120-7.
25. Sun JS, Wu SY, Lin FH. The role of muscle-derived stem cells in bone tissue engineering. Biomaterials. 2005;26:3953-60.
26. Collicott PE, Hughes I. Training in advanced trauma life support. JAMA. 1980;243:1156-9.
27. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974;2:81-4.
28. Abbreviated Injury Scale (AIS) 1990 - update 98. Barrington, IL: Association for the Advancement of Automotive Medicine; 1998.
29. Bujan J, Pascual G, Corrales C, Gomez-Gil V, Rodriguez M, Bellon JM. Muscle-derived stem cells in tissue engineering: defining cell properties suitable for construct design. Histol Histopathol. 2005;20:891-9.
30. Lecoeur L, Ouhayoun JP. In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells. Biomaterials. 1997;18:989-93.
31. Levy MM, Joyner CJ, Virdi AS, Reed A, Triffitt JT, Simpson AH, Kenwright J, Stein H, Francis MJ. Osteoprogenitor cells of mature human skeletal muscle tissue: an in vitro study. Bone. 2001;29:317-22.
32. Sakaguchi Y, Sekiya I, Yagishita K, Muneta T. Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum. 2005;52:2521-9.
33. Cadosch D, Thyer M, Gautschi OP, Lochnit G, Frey SP, Zellweger R, Filgueira L, Skirving AP. Functional and proteomic analysis of serum and cerebrospinal fluid derived from patients with traumatic brain injury: a pilot study. ANZ J Surg. 2010; In press.
34. Citta-Pietrolungo TJ, Alexander MA, Steg NL. Early detection of heterotopic ossification in young patients with traumatic brain injury. Arch Phys Med Rehabil. 1992;73:258-62.
35. Pape HC, Lehmann U, van Griensven M, Gansslen A, von Glinski S, Krettek C. Heterotopic ossifications in patients after severe blunt trauma with and without head trauma: incidence and patterns of distribution. J Orthop Trauma. 2001;15:229-37. (Pubitemid 32611309)
36. Spencer RF. The effect of head injury on fracture healing. A quantitative assessment. J Bone Joint Surg Br. 1987;69:525-8.
37. Le Du MH, Millan JL. Structural evidence of functional divergence in human alkaline phosphatases. J Biol Chem. 2002;277:49808-14.
38. Bosse A. [Clinical aspects, differential diagnosis and histogenesis of heterotopic ossification]. Veroff Pathol. 1997;146:1-168. German.
39. Purpura KA, Zandstra PW, Aubin JE. Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations. J Cell Biochem. 2003;90:109-20.
40. Grim M, Carlson BM. Alkaline phosphatase and dipeptidylpeptidase IV staining of tissue components of skeletal muscle: a comparative study. J Histochem Cytochem. 1990;38:1907-12. (Pubitemid 20382408)
41. Nakashima K, de Crombrugghe B. Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet. 2003;19:458-66. (Pubitemid 36930029)
42. Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002;108:17-29. (Pubitemid 34137009)
43. Tai G, Christodoulou I, Bishop AE, Polak JM. Use of green fluorescent fusion protein to track activation of the transcription factor osterix during early osteoblast differentiation. Biochem Biophys Res Commun. 2005;333:1116-22. (Pubitemid 40910119)
44. da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci. 2006;119(Pt. 11):2204-13. (Pubitemid 43960310)
45. Cohly HH, Buckley RC, Pecunia R, Das SK. Heterotopic bone formation: presentation of an experimental rat model and a clinical case. Biomed Sci Instrum. 2003;39:446-53. (Pubitemid 36433467)
46. Huggins CB. The phosphatase activity of transplants of the epithelium of the urinary bladder to the abdominal wall producing heterotopic ossification. Biochem J. 1931;25:728-32.
47. Puzas JE, Miller MD, Rosier RN. Pathologic bone formation. Clin Orthop Relat Res. 1989;245:269-81.
48. Soren A, Waugh TR. The morphologic and pathogenetic bases of heterotopic bone formation in the extremities. Zentralbl Allg Pathol. 1983;127:91-6.
49. Urist MR, Iwata H, Ceccotti PL, Dorfman RL, Boyd SD, McDowell RM, Chien C. Bone morphogenesis in implants of insoluble bone gelatin. Proc Natl Acad Sci U S A. 1973;70:3511-5.
50. van Kuijk AA, Geurts AC, van Kuppevelt HJ. Neurogenic heterotopic ossification in spinal cord injury. Spinal Cord. 2002;40:313-26.