Serum-mediated osteogenic effect in traumatic brain-injured patients

ANZ Journal of Surgery

Volumn 79, Issue 6, 2009, Pages 449-455

  Gautschi, Oliver P ^a,b   Cadosch, Dieter ^a   Frey, Sönke P ^a   Skirving, Allan P ^a   Filgueira, Luis ^a   Zellweger, René ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b Kantonsspital St Gallen ^*  (Switzerland)

Author keywords

Fracture healing; Heterotopic ossification; Osteogenic effect; Traumatic brain injury

Indexed keywords

ALKALINE PHOSPHATASE; CATHEPSIN K; MESSENGER RNA; PROTHROMBIN; SERINE PROTEINASE; SERINE PROTEINASE 7; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; BONE DEVELOPMENT; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FEMUR FRACTURE; FETUS CELL; FOLLOW UP; FRACTURE HEALING; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; OSTEOBLAST; TRAUMATIC BRAIN INJURY;

ADOLESCENT; ADULT; BRAIN INJURIES; CASE-CONTROL STUDIES; CELL LINE; CELLS, CULTURED; FEMALE; FOLLOW-UP STUDIES; FRACTURE HEALING; HUMANS; MALE; MIDDLE AGED; OSSIFICATION, HETEROTOPIC; OSTEOBLASTS; OSTEOGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKULL FRACTURES; YOUNG ADULT;

EID: 67650599101     PISSN: 14451433     EISSN: 14452197     Source Type: Journal    
DOI: 10.1111/j.1445-2197.2008.04803.x     Document Type: Article

References (40)

1. Kaplan FS, Glaser DL, Hebela N et al. Heterotopic ossification. J. Am. Acad. Orthop. Surg. 2004 12 : 116 25.
2. Kushwaha VP, Garland DG. Extremity fractures in the patient with a traumatic brain injury. J. Am. Acad. Orthop. Surg. 1998 6 : 298 307.
3. Tsur A, Sazbon L, Lotem M. Relationship between muscular tone, movement and periarticular new bone formation in postcoma-unaware (PC-U) patients. Brain Inj. 1996 10 : 259 62.
4. Banovac K, Gonzalez F. Evaluation and management of heterotopic ossification in patients with spinal cord injury. Spinal Cord 1997 35 : 158 62.
5. Garland DE, Dowling V. Forearm fractures in the head-injured adult. Clin. Orthop. Relat. Res. 1983 176 : 190 96.
6. Déjerine A, Ceillier A. Para-ostéo-arthropathies des paraplégiques par lésion medullaire: étude clinique et radiographique. Ann. Med. 1918 5 : 497 535.
7. Newman RJ, Stone MH, Mukherjee SK. Accelerated fracture union in association with severe head injury. Injury 1987 18 : 241 6.
8. Perkins R, Skirving AP. Callus formation and the rate of healing of femoral fractures in patients with head injuries. J. Bone Joint Surg. Br. 1987 69 : 521 4.
9. van Kuijk AA, Geurts AC, van Kuppevelt HJ. Neurogenic heterotopic ossification in spinal cord injury. Spinal Cord 2002 40 : 313 26.
10. Shehab D, Elgazzar AH, Collier BD. Heterotopic ossification. J. Nucl. Med. 2002 43 : 346 53.
11. Citta-Pietrolungo TJ, Alexander MA, Steg NL. Early detection of heterotopic ossification in young patients with traumatic brain injury. Arch. Phys. Med. Rehabil. 1992 73 : 258 62.
12. Garland DE. Clinical observations on fractures and heterotopic ossification in the spinal cord and traumatic brain injured populations. Clin. Orthop. Relat. Res. 1988 233 : 86 101. (Pubitemid 18211957)
13. Garland DE. A clinical perspective on common forms of acquired heterotopic ossification. Clin. Orthop. Relat. Res. 1991 263 : 13 29.
14. Bidner SM, Rubins IM, Desjardins JV et al. Evidence for a humoral mechanism for enhanced osteogenesis after head injury. J. Bone Joint Surg. Am. 1990 72 : 1144 9.
15. Brighton CT, Hunt RM. Early histologic and ultrastructural changes in microvessels of periosteal callus. J. Orthop. Trauma 1997 11 : 244 53.
16. Gautschi OP, Toffoli AM, Joesbury KA et al. Osteoinductive effect of cerebrospinal fluid from brain-injured patients. J. Neurotrauma 2007 24 : 154 62.
17. Boes M, Kain M, Kakar S et al. Osteogenic effects of traumatic brain injury on experimental fracture-healing. J. Bone Joint Surg. Am. 2006 88 : 738 43.
18. Chalmers J, Gray DH, Rush J. Observations on the induction of bone in soft tissues. J. Bone Joint Surg. Br. 1975 57 : 36 45.
19. Filgueira L, Meagher J, Al-Mushaiqri M et al. Fulvestrant, an estrogen receptor antagonist, blocks proliferation and differentiation of cultured primary human osteoblasts. Bone 2005 36 : S463 4.
20. Cory AH, Owen TC, Barltrop JA, Cory JG. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 1991 3 : 207 12.
21. Giannoudis PV, Mushtaq S, Harwood P et al. Accelerated bone healing and excessive callus formation in patients with femoral fracture and head Injury. Injury 2006 37 : S18 24.
22. Garland DE, Todler L. Fractures of the tibial diaphysis in adults with head injuries. Clin. Orthop. Relat. Res. 1980 150 : 198 202. (Pubitemid 10039051)
23. Yen ML, Chien CC, Chin IM et al. Multilineage differentiation and characterization of the human foetal osteoblastic 1.19 cell line: a possible in vitro model of human mesenchymal progenitors. Stem Cells 2007 25 : 125 131.
24. Canalis E. Effect of growth factors on bone cell replication and differentiation. Clin. Orthop. Relat. Res. 1985 193 : 246 63.
25. Dimitriou R, Tsiridis E, Giannoudis PV. Current concepts of molecular aspects of bone healing. Injury 2005 36 : 1392 404.
26. Raisz LG, Canalis EM, Dietrich JW et al. Hormonal regulation of bone formation. Recent Prog. Horm. Res. 1978 34 : 335 56.
27. Arosarena O, Collins W. Comparison of BMP-2 and -4 for rat mandibular bone regeneration at various doses. Orthod. Craniofac. Res. 2005 8 : 267 76.
28. Estrores IM, Harrington A, Banovac K. C-reactive protein and erythrocyte sedimentation rate in patients with heterotopic ossification after spinal cord injury. J. Spinal Cord Med. 2004 27 : 434 7.
29. Kossmann T, Hans VH, Imhof HG et al. Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock 1995 4 : 311 17.
30. Baumann H, Gauldie J. The acute phase response. Immunol. Today 1994 15 : 74 80. (Pubitemid 24049800)
31. Hock JM, Fitzpatrick LA, Bilezikian JP. Actions of parathyroid hormone. In : Bilezikian JP, Raisz LG, Rodan GA (eds). Principles of Bone Biology, 2nd edn. San Diego, CA : Academic, 2002 463 81.
32. Wang YH, Liu Y, Rowe DW. Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblast in primary osteoblast cultures. Am. J. Physiol. Endocrinol. Metab. 2007 292 : 594 603.
33. Mandelin J, Hukkanen M, Li TF et al. Human osteoblasts produce cathepsin K. Bone 2006 38 : 769 77.
34. Camozzi V, Tossi A, Simoni E et al. Role of biochemical markers of bone remodeling in clinical practice. J. Endocrinol. Invest. 2007 30 : 13 17.
35. Komori T. Regulation of bone development and maintenance by Runx2. Front. Biosci. 2008 13 : 898 903. (Pubitemid 351594735)
36. Wildburger R, Zarkovic N, Dobnig H et al. Post-traumatic dynamic change of carboxyterminal propeptide of type I procollagen, alkaline phosphatase and its isoenzymes as predictors for enhanced osteogenesis in patients with severe head injury. Res. Exp. Med. (Berl.) 1994 194 : 247 59.
37. Wildburger R, Zarkovic N, Petek W et al. [Hypertrophic callus formation and craniocerebral trauma: early diagnosis and behavior of basic fibroblast growth factor]. Unfallchirurg 1996 99 : 17 23. (Pubitemid 26064682)
38. Kurer MH, Khoker MA, Dandona P. Human osteoblast stimulation by sera from paraplegic patients with heterotopic ossification. Paraplegia 1992 30 : 165 8.
39. Renfree KJ, Banovac K, Hornicek FJ et al. Evaluation of serum osteoblast mitogenic activity in spinal cord and head injury patients with acute heterotopic ossification. Spine 1994 19 : 740 46.
40. Klein BY, Shohami E, Reikinshtein Y. Serum-mediated osteogenic effects of head injury on cultured rat marrow stromal cells. Calcif. Tissue Int. 1999 65 : 217 22.