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Volumn 23, Issue 5, 2010, Pages 1309-1316

Tumor-targeted efficiency of shRNA vector harboring chimera hTERT/U6 promoter

Author keywords

Human telomerase reverse transcriptase; Promoter; Short hairpin RNA; Telomerase; Tumor targeted

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; SHORT HAIRPIN RNA; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 77950842157     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000765     Document Type: Article
Times cited : (4)

References (28)
  • 1
    • 0029894237 scopus 로고    scopus 로고
    • Telomere length regulation
    • Greider CW: Telomere length regulation. Annu Rev Biochem 65: 337-365, 1996.
    • (1996) Annu Rev Biochem , vol.65 , pp. 337-365
    • Greider, C.W.1
  • 2
    • 0036591887 scopus 로고    scopus 로고
    • Mechanisms of chromosomeend protection
    • Cervantes RB and Lundblad V: Mechanisms of chromosomeend protection. Curr Opin Cell Biol 14: 351-356, 2002.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 351-356
    • Cervantes, R.B.1    Lundblad, V.2
  • 3
    • 19844382620 scopus 로고    scopus 로고
    • Senescence and immortalization: Role of telomeres and telomerase
    • Shay JW and Wright WE: Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 26: 867-874, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 867-874
    • Shay, J.W.1    Wright, W.E.2
  • 4
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • Feng J, Funk WD, Wang SS, et al: The RNA component of human telomerase. Science 269: 1236-1241, 1995.
    • (1995) Science , vol.269 , pp. 1236-1241
    • Feng, J.1    Funk, W.D.2    Wang, S.S.3
  • 5
    • 0030819894 scopus 로고    scopus 로고
    • Telomerase catalytic subunit homologs from fission yeast and human
    • Nakamura TM, Morin GB, Chapman KB, et al: Telomerase catalytic subunit homologs from fission yeast and human. Science 277: 955-959, 1997.
    • (1997) Science , vol.277 , pp. 955-959
    • Nakamura, T.M.1    Morin, G.B.2    Chapman, K.B.3
  • 6
    • 0032911694 scopus 로고    scopus 로고
    • Direct activation of TERT transcription by c-myc
    • Wu KJ, Grandori C, Amacker M, et al: Direct activation of TERT transcription by c-myc. Nat Genet 21: 220-224, 1999.
    • (1999) Nat Genet , vol.21 , pp. 220-224
    • Wu, K.J.1    Grandori, C.2    Amacker, M.3
  • 7
    • 51849160271 scopus 로고    scopus 로고
    • Tumor-targeted radionuclide imaging and therapy based on human sodium iodide symporter gene driven by a modified telomerase reverse transcriptase promoter
    • Kim SH, Chung HK, Kang JH, et al: Tumor-targeted radionuclide imaging and therapy based on human sodium iodide symporter gene driven by a modified telomerase reverse transcriptase promoter. Hum Gene Ther 19: 951-957, 2008.
    • (2008) Hum Gene Ther , vol.19 , pp. 951-957
    • Kim, S.H.1    Chung, H.K.2    Kang, J.H.3
  • 8
    • 0036782884 scopus 로고    scopus 로고
    • Telomerase: A target for cancer therapeutics
    • Shay JW and Wright WE: Telomerase: A target for cancer therapeutics. Cancer Cell 2: 257-265, 2002.
    • (2002) Cancer Cell , vol.2 , pp. 257-265
    • Shay, J.W.1    Wright, W.E.2
  • 9
    • 3543009635 scopus 로고    scopus 로고
    • RNA interference: A potent tool for gene-specific therapeutics
    • Ichim TE, Li M, Qian H, et al: RNA interference: a potent tool for gene-specific therapeutics. Am J Transplant 4: 1227-1236, 2004.
    • (2004) Am J Transplant , vol.4 , pp. 1227-1236
    • Ichim, T.E.1    Li, M.2    Qian, H.3
  • 10
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ and Rossi JJ: Unlocking the potential of the human genome with RNA interference. Nature 431: 371-378, 2004.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 11
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: Short RNAs that silence gene expression
    • Dykxhoorn DM, Novina CD and Sharp PA: Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol 4: 457-467, 2003.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 12
    • 4644223259 scopus 로고    scopus 로고
    • Mechanisms of gene silencing by double-stranded RNA
    • Meister G and Tuschl T: Mechanisms of gene silencing by double-stranded RNA. Nature 431: 343-349, 2004.
    • (2004) Nature , vol.431 , pp. 343-349
    • Meister, G.1    Tuschl, T.2
  • 13
    • 0042267194 scopus 로고    scopus 로고
    • Efficient lentiviral vectors for short hairpin RNA delivery into human cells
    • An DS, Xie Y, Mao SH, et al: Efficient lentiviral vectors for short hairpin RNA delivery into human cells. Hum Gene Ther 14: 1207-1212, 2003.
    • (2003) Hum Gene Ther , vol.14 , pp. 1207-1212
    • An, D.S.1    Xie, Y.2    Mao, S.H.3
  • 14
    • 32444445166 scopus 로고    scopus 로고
    • RNAi-hTERT inhibition hepatocellular carcinoma cell proliferation via decreasing telomerase activity
    • Zhang PH, Zou L and Tu ZG: RNAi-hTERT inhibition hepatocellular carcinoma cell proliferation via decreasing telomerase activity. J Surg Res 131: 143-149, 2006.
    • (2006) J Surg Res , vol.131 , pp. 143-149
    • Zhang, P.H.1    Zou, L.2    Tu, Z.G.3
  • 15
    • 2942709631 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT)
    • Nishi H, Nakada T, Kyo S, et al: Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). Mol Cell Biol 24: 6076-6083, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 6076-6083
    • Nishi, H.1    Nakada, T.2    Kyo, S.3
  • 16
    • 33751106653 scopus 로고    scopus 로고
    • New approaches to molecular cancer therapeutics
    • Collins I and Workman P: New approaches to molecular cancer therapeutics. Nat Chem Biol 2: 689-700, 2006.
    • (2006) Nat Chem Biol , vol.2 , pp. 689-700
    • Collins, I.1    Workman, P.2
  • 17
    • 36349032759 scopus 로고    scopus 로고
    • MicroRNAs in disease and potential therapeutic applications
    • Soifer HS, Rossi JJ and Sætrom P: MicroRNAs in disease and potential therapeutic applications. Mol Ther 15: 2070-2079, 2007.
    • (2007) Mol Ther , vol.15 , pp. 2070-2079
    • Soifer, H.S.1    Rossi, J.J.2    Sætrom, P.3
  • 18
    • 0038746733 scopus 로고    scopus 로고
    • The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochoremicrotubule attachment and in maintaining the spindle assembly checkpoint
    • Hauf S, Cole RW, LaTerra S, et al: The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochoremicrotubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol 161: 281-294, 2003.
    • (2003) J Cell Biol , vol.161 , pp. 281-294
    • Hauf, S.1    Cole, R.W.2    Laterra, S.3
  • 19
    • 0042941765 scopus 로고    scopus 로고
    • Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
    • Chen Y, Stamatoyannopoulos G and Song CZ: Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res 63: 4801-4804, 2003.
    • (2003) Cancer Res , vol.63 , pp. 4801-4804
    • Chen, Y.1    Stamatoyannopoulos, G.2    Song, C.Z.3
  • 20
    • 4744373229 scopus 로고    scopus 로고
    • Noise amidst the silence: Off-target effects of siRNAs?
    • Jackson AL and Linsley PS: Noise amidst the silence: off-target effects of siRNAs? Trends Genet 20: 521-524, 2004.
    • (2004) Trends Genet , vol.20 , pp. 521-524
    • Jackson, A.L.1    Linsley, P.S.2
  • 21
    • 0042972933 scopus 로고    scopus 로고
    • Activation of the interferon system by short-interfering RNAs
    • Sledz CA, Holko M, de Veer MJ, et al: Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 5: 834-839, 2003.
    • (2003) Nat Cell Biol , vol.5 , pp. 834-839
    • Sledz, C.A.1    Holko, M.2    De Veer, M.J.3
  • 22
    • 34247141017 scopus 로고    scopus 로고
    • In vivo gene silencing in solid tumors by targeted electrically mediated siRNA delivery
    • Golzio M, Mazzolini L, Ledoux A, et al: In vivo gene silencing in solid tumors by targeted electrically mediated siRNA delivery. Gene Ther 14: 752-759, 2007.
    • (2007) Gene Ther , vol.14 , pp. 752-759
    • Golzio, M.1    Mazzolini, L.2    Ledoux, A.3
  • 23
    • 33745608078 scopus 로고    scopus 로고
    • Off-target effects by siRNA can induce toxic phenotype
    • Fedorov Y, Anderson EM, Birmingham A, et al: Off-target effects by siRNA can induce toxic phenotype. RNA 12: 1188-1196, 2006.
    • (2006) RNA , vol.12 , pp. 1188-1196
    • Fedorov, Y.1    Anderson, E.M.2    Birmingham, A.3
  • 24
    • 3242677639 scopus 로고    scopus 로고
    • SiRNAs: Applications in functional genomics and potential as therapeutics
    • Dorsett Y and Tuschl T: siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 3: 318-329, 2004.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 25
    • 12144288006 scopus 로고    scopus 로고
    • A resource for largescale RNA-interference-based screens in mammals
    • Paddison PJ, Silva JM, Conklin DS, et al: A resource for largescale RNA-interference-based screens in mammals. Nature 428: 427-431, 2004.
    • (2004) Nature , vol.428 , pp. 427-431
    • Paddison, P.J.1    Silva, J.M.2    Conklin, D.S.3
  • 26
    • 9644275599 scopus 로고    scopus 로고
    • Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
    • Kim B, Tang Q, Biswas PS, et al: Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol 165: 2177-2185, 2004.
    • (2004) Am J Pathol , vol.165 , pp. 2177-2185
    • Kim, B.1    Tang, Q.2    Biswas, P.S.3
  • 27
    • 34547587566 scopus 로고    scopus 로고
    • Antiviral immunity directed by small RNAs
    • Ding SW and Voinnet O: Antiviral immunity directed by small RNAs. Cell 130: 413-426, 2007.
    • (2007) Cell , vol.130 , pp. 413-426
    • Ding, S.W.1    Voinnet, O.2
  • 28
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • Takei Y, Kadomatsu K, Yuzawa Y, et al: A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 64: 3365-3370, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.