Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis

Biochemistry

Volumn 49, Issue 14, 2010, Pages 3009-3023

  Zhang, Xuemei ^a   Motea, Edward ^b   Lee, Irene ^b   Berdis, Anthony J ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5-NITROINDOLE; BASE PAIRS; BASE STACKING; CATALYTIC EFFICIENCIES; DATA SETS; DNA POLYMERASE; DNA POLYMERIZATION; ELECTRON SURFACE; HIGH FIDELITY; HYDROGEN BONDING INTERACTIONS; HYDROGEN BONDINGS; HYDROPHOBIC GROUPS; HYDROPHOBIC NATURE; NUCLEOBASES; POLYMERIZATION REACTION; PRIMER EXTENSION; SHAPE AND SIZE; TEMPLATE STRAND;

DNA; GENES; HYDROGEN; HYDROPHOBICITY; NUCLEOTIDES; POLYMERIZATION; POLYMERS;

HYDROGEN BONDS;

5 INDOLYL NUCLEOTIDE; 5 NITROINDOLE; 5 NITROINDOLYL 2' DEOXYRIBOSIDE TRIPHOSPHATE; DNA; DNA POLYMERASE; EXONUCLEASE; INDOLE DERIVATIVE; NUCLEIC ACID BASE; NUCLEOSIDE PHOSPHATE; NUCLEOTIDE; PHOSPHATE; PURINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; ELECTRON; ENTROPY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HYDROGEN BOND; HYDROPHOBICITY; POLYMERIZATION; PRIORITY JOURNAL; PYROPHOSPHOROLYSIS; SURFACE PROPERTY;

DIPHOSPHATES; DNA-DIRECTED DNA POLYMERASE; ENTROPY; HYDROGEN BONDING; INDOLES; KINETICS; NUCLEOTIDES; PURINE NUCLEOTIDES; PYRIMIDINE NUCLEOTIDES;

EID: 77950631900     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901523y     Document Type: Article

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