Hydrophobicity, shape, and π-electron contributions during translesion DNA synthesis

Journal of the American Chemical Society

Volumn 128, Issue 1, 2006, Pages 143-149

  Zhang, Xuemei ^b   Lee, Irene ^b   Zhou, Xiang ^c   Berdis, Anthony J ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Chemistry ^*  (United States)

^c CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CARRIER CONCENTRATION; CELLULOSE DERIVATIVES; CONFORMATIONS; DISSOCIATION; ENZYMES; GROUND STATE; MUTAGENESIS; SYNTHESIS (CHEMICAL);

5-CYCLOHEXYL-INDOLE; CATALYTIC EFFICIENCY; KPOL; NUCLEOTIDES;

DNA;

5 CYCLOHEXENE INDOLE DERIVATIVE; 5 CYCLOHEXYLINDOLE DERIVATIVE; DNA; DNA POLYMERASE; INDOLE DERIVATIVE; NUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DNA SYNTHESIS; DNA TEMPLATE; ELECTRON; ENZYME CONFORMATION; ENZYME KINETICS; HYDROPHOBICITY; MUTAGENESIS; REACTION ANALYSIS;

DNA; DNA DAMAGE; DNA-DIRECTED DNA POLYMERASE; ELECTRONS; HYDROPHOBICITY; KINETICS; NUCLEIC ACID CONFORMATION; NUCLEOTIDES;

EID: 30744471162     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0546830     Document Type: Article

References (26)

1. (a) Wagner, J.; Etienne, H.; Janel-Bintz, R.; Fuchs, R. P. DNA Repair (Amst) 2002, 1, 159-167.
2. (b) Pages, V.; Fuchs, R. P. Oncogene 2002, 21, 8957-8966
3. Lindahl, T. Nature 1993, 362, 709-715.
4. Boileux, S.; Guillet, M. DNA Repair (Amst) 2004, 3, 1-12.
5. Schaaper, R. M.; Kunkel, T. A.; Loeb, L. A. Proc. Natl. Acad. Sci. U.S.A. 1983, 80, 487-491.
6. (b) Boiteux, S.; Laval, J. Biochemistry 1982, 21, 6746-6751.
7. (c) Efrati, E.; Tocco, G.; Eritja, R.; Wilson, S. H.; Goodman, M. F. J. Biol. Chem. 1997, 272, 2559-2569.
8. (d) Mozzherin, D. J.; Shibutani, S.; Tan, C.-K.; Downey, K. M.; Fisher, P. A. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 6126-6131.
9. (a) Kool, E. T. Annu. Rev. Biophys. Biomol. Struct. 2001, 30, 1-22.
10. (b) Matray, T. J.; Kool, E. T. Nature 1999, 399, 704-709.
11. (a) Vesnaver, G.; Change, C. N.; Eisenberg, M.; Grollman, A. P.; Breslauer, K. J. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 3614-3618.
12. (b) Goodman, M. F.; Ceighton, S.; Bloom, L. B.; Petruska, J. Crit. Rev. Biochem. Mol. Biol. 1993, 28, 83-126.
13. Cuniasse, P.; Fazakerly, G. V.; Guschlbauer, W.; Kaplan, B. E.; Sowers, L. C. J. Mol. Biol. 1987, 213, 303-314.
14. Berdis, A. J. Biochemistry 2001, 40, 7180-7191.
15. Reineks, E. Z.; Berdis, A. J. Biochemistry 2004, 43, 393-404.
16. Zhang, Lee, I.; Berdis, A. J. Biochemistry, 2005, 44, 1703-1711.
17. Zhang, Lee, I.; Berdis, A. J. Org. Biomol. Chem. 2004, 2, 1703-1711.
18. (a) Moyer, M. P.; Shiurba, J. F.; Rapoport, H. J. Org. Chem. 1986, 51, 5106-5110.
19. (b) Girgis, N. S.; Cottam, H. B.; Robins, R. K. J. Heterocycl. Chem. 1988, 25, 361.
20. Loakes, D.; Brown, D. M.; Linde, S.; Hill, F. Nucleic Acids Res. 1995, 23, 2361-2366.
21. Johnson, K. A. Methods Enzymol. 1995, 249, 38-61.
22. Ferscht, A. Enzyme Structure and Mechanism; W. H. Freeman and Company: New York; pp 98-101.
23. (a) Franklin, M. C.; Wang, J.; Steitz, T. A. Cell 2001, 105, 657-667.
24. (b) Hogg, M.; Wallace, S. S.; Doublie, S. EMBO J. 2004, 23, 1483-1493.
25. Johnson, S. J.; Taylor, J. S.; Beese, L. S. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 3895-3900.
26. Li, Y.; Korolev, S.; Waksman, G. EMBO J. 1998, 24, 7514-7525.