Menopause

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition

Volumn , Issue , 2009, Pages 95-97

  Reid, Ian R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Acid base; BMD; Bone formation; Bone mass; Bone resorption; Calcium absorption; Calcium balance; Cytokines; Estrogen; Fractures; Growth factors; Histomorphometry; Osteoporosis; Parathyroid hormone; Progesterone; Renal tubular reabsorption of calcium; Serum calcium fractions

Indexed keywords

EID: 77950613441     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470623992.ch19     Document Type: Chapter

References (42)

1. Chapurlat RD, Garnero P, Sornay-Rendu E, Arlot ME, Claustrat B, Delmas PD 2000 Longitudinal study of bone loss in pre- and perimenopausal women: Evidence for bone loss in perimeno-pausal women. Osteoporos Int 11:493-498.
2. Sowers MR, Jannausch M, McConnell D, Little R, Greendale GA, Finkelstein JS, Neer RM, Johnston J, Ettinger B 2006 Hormone predictors of bone mineral density changes during the menopausal transition. J Clin Endocrinol Metab 91:1261-1267.
3. Macdonald HM, New SA, Campbell MK, Reid DM 2005 Influence of weight and weight change on bone loss in perimenopausal and early postmenopausal Scottish women. Osteoporos Int 16:163-171.
4. Heaney RP, Recker RR, Saville PD 1978 Menopausal changes in bone remodeling. J Lab Clin Med 92:964-970.
5. Garnero P, Sornayrendu E, Chapuy MC, Delmas PD 1996 Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11:337-349.
6. Akhter MP, Lappe JM, Davies KM, Recker RR 2007 Transmeno-pausal changes in the trabecular bone structure. Bone 41:111-116.
7. Cooper DM, Thomas CD, Clement JG, Turinsky AL, Sensen CW, Hallgrimsson 2007 Age-dependent change in the 3D structure of cortical porosity at the human femoral midshaft. Bone 40:957-965.
8. Okazaki R, Inoue D, Shibata M, Saika M, Kido S, Ooka H, Tomi-yama H, Sakamoto Y, Matsumoto T 2002 Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta. Endocrinology 143:2349-2356.
9. Fujita M, Urano T, Horie K, Ikeda K, Tsukui T, Fukuoka H, Tsutsumi O, Ouchi Y, Inoue S 2002 Estrogen activates cyclin-dependent kinases 4 and 6 through induction of cyclin D in rat primary osteoblasts. Biochem Biophys Res Commun 299:222-228.
10. Tomkinson A, Reeve J, Shaw RW, Noble BS 1997 The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J Clin Endocrinol Metab 82:3128-3135.
11. Gohel A, McCarthy MB, Gronowicz G 1999 Estrogen prevents glucocorticoid-induced apoptosis in osteoblasts in vivo and in vitro. Endocrinology 140:5339-5347.
12. Vedi S, Compston JE 1996 The effects of long-term hormone replacement therapy on bone remodeling in postmenopausal women. Bone 19:535-539.
13. Bord S, Beavan S, Ireland D, Horner A, Compston JE 2001 Mechanisms by which high-dose estrogen therapy produces anabolic skeletal effects in postmenopausal women: Role of locally produced growth factors. Bone 29:216-222.
14. Kameda T, Mano H, Yuasa T, Mori Y, Miyazawa K, Shiokawa M, Nakamaru Y, Hiroi E, Hiura K, Kameda A, Yang NN, Hakeda Y, Kumegawa M 1997 Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts. J Exp Med 186:489-95.
15. Syed F, Khosla S 2005 Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 328:688-696.
16. Manolagas SC, Jilka RL 1995 Mechanisms of disease: Bone marrow, cytokines, and bone remodeling - Emerging insights into the pathophysiology of osteoporosis. N Engl J Med 332:305-311.
17. Ryan MR, Shepherd R, Leavey JK, Gao YH, Grassi F, Schnell FJ, Qian WP, Kersh GJ, Weitzmann MN, Pacifici R 2005 An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency. Proc Natl Acad Sci USA 102:16735-16740.
18. Cenci S, Toraldo G, Weitzmann MN, Roggia C, Gao YH, Qian WP, Sierra O, Pacifici R 2003 Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci USA 100:10405-10410.
19. Rogers A, Eastell R 1998 Effects of estrogen therapy of postmenopausal women on cytokines measured in peripheral blood. J Bone Miner Res 13:1577-1586.
20. Sunyer T, Lewis J, Collin-Osdoby P, Osdoby P 1999 Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells. J Clin Invest 103:14091418.
21. Charatcharoenwitthaya N, Khosla S, Atkinson EJ, McCready LK, Riggs BL 2007 Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women. J Bone Miner Res 22:724-729.
22. Kimble RB, Srivaslava S, Ross FP, Matayoshi A, Pacifici R 1996 Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-l-and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production. J Biol Chem 271:28890-28897.
23. Gao YH, Qian WP, Dark K, Toraldo G, Lin ASP, Guldberg RE, Flavell RA, Weitzmann MN, Pacifici R 2004 Estrogen prevents bone loss through transforming growth factor beta signaling in T cells. Proc Natl Acad Sci USA 101:16618-16623.
24. Weitzmann MN, Pacifici R 2006 Estrogen deficiency and bone loss: An inflammatory tale. J Clin Invest 116:1186-1194.
25. Almeida M, Han L, Martin-Millan M, Plotkin LI, Stewart SA, Roberson PK, Kousteni S, O'Brien CA, Bellido T, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC 2007 Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem 282:27285-27297.
26. Mann V, Huber C, Kogianni G, Collins F, Noble B 2007 The antioxidant effect of estrogen and selective estrogen receptor modulators in the inhibition of osteocyte apoptosis in vitro. Bone 40:674-684.
27. Ralston SH 1997 The Michael-Mason-Prize essay 1997-nitric oxide and bone-what a gas. Br J Rheumatol 36:831-838.
28. Friend KE, Hartman ML, Pezzoli SS, Clasey JL, Thorner MO 1996 Both oral and transdermal estrogen increase growth hormone release in postmenopausal women-a clinical research center study. J Clin Endocrinol Metab 81:2250-2256.
29. Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M 2006 FSH directly regulates bone mass. Cell 125:247-260.
30. Heaney RP, Recker RR, Saville PD 1978 Menopausal changes in calcium balance performance. J Lab Clin Med 92:953-963.
31. Arjandi BH, Salih MA, Herbert DC, Sims SH, Kalu DN 1993 Evidence for estrogen receptor-linked calcium transport in the intestine. Bone Miner 21:63-74.
32. Van Cromphaut SJ, Rummens K, Stockmans 1, Van Herck E, Dijcks FA, Ederveen A, Carmeliet P, Verhaeghe J, Bouillon R, Carmeliet G 2003 Intestinal calcium transporter genes are upregu-lated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms. J Bone Miner Res 18:17251736.
33. Nordin BEC, Wlshart JM, Clifton PM, McArthur R, Scopacasa F, Need AG, Morris HA, O'Loughlin PD, Horowitz M 2004 A longitudinal study of bone-related biochemical changes at the menopause. Clin Endocrinol (Oxf) 61:123-130.
34. McKane WR, Khosla S, Burritt MF, Kao PC, Wilson DM, Ory SJ, Riggs BL 1995 Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmeno-pause-A clinical research center study. J Clin Endocrinol Metab 80:3458-3464.
35. Dick IM, Liu J, Glendenning P, Prince RL 2003 Estrogen and androgen regulation of plasma membrane calcium pump activity in immortalized distal tubule kidney cells. Mol Cell Endocrinol 212:11-18.
36. Duarte B, Hargis GK, Kukreja SC 1988 Effects of estradiol and progesterone on parathyroid hormone secretion from human parathyroid tissue. J Clin Endocrinol Metab 66:584-587.
37. Greenberg C, Kukreja SC, Bowser EN, Hargis GK, Henderson WJ, Williams GA 1987 Parathyroid hormone secretion: Effect of estradiol and progesterone. Metabolism 36:151-154.
38. Sokoll LJ, Dawson-Hughes B 1989 Effect of menopause and aging on serum total and ionized calcium and protein concentrations. Calcif Tissue Int 44:181-185.
39. Aitken JM, Lindsay R, Hart DM 1974 The redistribution of body sodium in women on long-term estrogen therapy. Clin Sci Mol Med 47:179-187.
40. Minkoff JR. Young G, Grant B, Marcus R 1986 Interactions of medroxyprogesterone acetate with estrogen on the calcium-parathyroid axis in post-menopausal women. Maturitas 8:35-15.
41. Bayliss DA, Millhorn DE 1992 Central neural mechanisms of progesterone action: Application to the respiratory system. J AppI Physiol 73:393-04.
42. Orr-Walker BJ, Home AM, Evans MC, Grey AB. Murray MAF, McNeil AR, Reid IR 1999 Hormone replacement therapy causes a respiratory alkalosis in normal postmenopausal women. J Clin Endocrinol Metab 84:1997-2001.