A longitudinal study of bone-related biochemical changes at the menopause

Clinical Endocrinology

Volumn 61, Issue 1, 2004, Pages 123-130

  Nordin, B E Christopher ^a,b,c   Wishart, Judith M ^a   Clifton, Peter M ^b   McArthur, Rosemary ^b   Scopacasa, Franca ^a   Need, Allan G ^a,b   Morris, Howard A ^a,b   O'Loughlin, Peter D ^a   Horowitz, Michael ^a,b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b ROYAL ADELAIDE HOSPITAL   (Australia)

^c INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DEOXYPYRIDINOLINE; PARATHYROID HORMONE; PYRIDINOLINE; VITAMIN D;

ADULT; ADVERTIZING; ARTICLE; BIOCHEMISTRY; BLOOD SAMPLING; BONE METABOLISM; CALCIUM ABSORPTION; CALCIUM BLOOD LEVEL; CALCIUM METABOLISM; CALCULATION; CLINICAL EXAMINATION; CONTROLLED STUDY; CORRELATION ANALYSIS; EVALUATION; FEMALE; FREEZING; HOSPITAL ADMISSION; HUMAN; HUMAN EXPERIMENT; LONGITUDINAL STUDY; MENOPAUSE; NORMAL HUMAN; OSTEOLYSIS; PREMENOPAUSE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THAWING; URINALYSIS; VOLUNTEER;

ADULT; AMINO ACIDS; BIOLOGICAL MARKERS; BONE AND BONES; BONE RESORPTION; CALCIUM; FEMALE; HUMANS; LONGITUDINAL STUDIES; MENOPAUSE; MIDDLE AGED; PARATHYROID HORMONE;

EID: 3242657942     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2004.02066.x     Document Type: Article

References (52)

1. Adami, S., Gatti, D., Bertoldo, F., Rossini, M., Fratta-Pasini, A., Zamberlan, N., Facci, E. & LoCascio, V. (1992) The effects of menopause and estrogen replacement therapy on the renal handling of calcium. Osteoporosis International, 2, 180-185.
2. Bolander, M.E., Joyce, M.E., Boden, S.D., Oliver, B. & Ahlke, H. (1990) Estrogen receptor mRNA expression during fracture healing in the rat detected by polymerase chain reaction amplication. In: Calcium Regulation and Bone Metabolism (eds D. V. Cohn, F. H. Glorieux & T. J. Martin), pp. 382-387. Elsevier, New York.
3. Boucher, A., D'Amour, P., Hamel, L., Fugère, P., Gascon-Barré, M., Lepage, R. & Ste-Marie, L.G. (1989) Estrogen replacement decreases the set point of parathyroid hormone stimulation by calcium in normal postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 68, 831-836.
4. 3. Journal of Clinical Investigatgion, 67, 589-596.
5. Burger, H.G., Dudley, E.C., Hopper, J.L., Gromme, N., Guthrie, J.R., Green, A. & Dennerstein, L. (1999) Prospectively measured levels of serum follicle-stimulating hormone, estradiol, and the dimeric inhibins during the menopausal transition in a population-based cohort of women. Journal of Clinical Endocrinology and Metabolism, 84, 4025-4030.
6. Burger, H.G., Dudley, E.C., Cui, J., Dennerstein, L. & Hopper, J.L. (2000). A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition. Journal of Clinical Endocrinology and Metabolism, 85, 2832-2838.
7. Campbell-Thompson, M.L. (1997) Estrogen receptor α and β expression in upper gastrointestinal tract with regulation of trefoil factor family 2 mRNA levels in ovariectomized rats. Biochemical and Biophysical Research Communications, 240, 478-483.
8. Cosman, F., Shen, V., Xie, F., Seibel, M., Ratcliffe, A. & Lindsay, R. (1993) Estrogen protection against bone resorbing effects of parathyroid hormone infusion. Annals of International Medicine, 118, 337-343.
9. Devine, A., Prince, R.L., Kerr, D.A., Dick, I.M., Criddle, R.A., Kent, G.N., Price, R.I. & Garcia Webb, P. (1993) Correlates of intestinal calcium absorption in women 10 years past the menopause. Calcified Tissue International, 52, 358-360.
10. Dick, I.M., Prince, R.L., Kelly, J.J. & Ho, K.K. (1995) Oestrogen effects on calcitriol levels in post-menopausal women: a comparison of oral versus transdermal administration. Clinical Endocrinology, 43, 219-224.
11. Ebeling, P.R., Yergey, A.L., Vieira, N.E., Burritt, M.F., O'Fallon, W.M., Kumar, R. & Riggs, B.L. (1994) Influence of age on effects of endogenous 1,25-dihydroxyvitamin D on calcium absorption in normal women. Calcified Tissue International, 55, 330-334.
12. 3 in oophorectomized women. Journal of Clinical Endocrinology and Metabolism, 71, 1288-1293.
13. Girasole, G., Jilka, R.L., Passeri, G., Boswell, S., Boder, G., Williams, D.C. & Manolagas, S.C. (1992) 17β-Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro. a potential mechanism for the antiosteoporotic effect of estrogens. Journal of Clinical Investigation, 89, 883-891.
14. Grant, F.D., Conlin, P.R. & Brown, E.M. (1990) Rate and concentration dependence of parathyroid hormone dynamics during stepwise changes in serum ionized calcium in normal humans. Journal of Clinical Endocrinology and Metabolism, 71, 370-378.
15. Guthrie, J.R., Ball, M., Dudley, E.C., Garamszegi, C.V., Wahlqvist, M.L., Dennerstein, L. & Burger, H.G. (2001) Impaired fasting glycaemia in middle-aged women: a prospective study. International Journal of Obesity and Related Metabolic Disorders, 25, 646-651.
16. Guthrie, J.R., Ebeling, P.R., Hopper, J.L., Barrett-Connor, E., Dennerstein, L., Dudley, E.C., Burger, H.G. & Wark, J.D. (1998) A prospective study of bone loss in menopausal Australian-born women. Osteoporosis International, 8, 282-290.
17. Hall, G., Collins, A., Csemiczky, G. & Landgren, B.M. (2002) Lipoproteins and BMI. a comparison between women during transit menopause and regularly menstruating healthy women. Maturitas, 41, 177-185.
18. Heaney, R.P. (1965) A unified concept of osteoporosis. American Journal of Medicine, 39, 377-380.
19. Heaney, R.P. (2000) Calcium, dairy products and osteoporosis. Journal of the American College of Nutrition, 19, 83S-99S.
20. Heaney, R.P., Recker, R.R. & Saville, P.D. (1978) Menopausal changes in calcium balance performance. Journal of Laboratory and Clinical Medicine, 92, 953-963.
21. Holzherr, M.L., Retallack, R.W., Gutteridge, D.H., Price, R.I., Faulkner, D.L., Wilson, S.G., Will, R.K., Stewart, G.O., Stuckey, B.G.A., Prince, R.L., Criddle, R.A., Kent, G.N., Bhagat, C.I., Dhaliwal, S.S. & Jamrozik, K. (2000) Calcium absorption in postmenopausal osteoporosis: benefit of HRT plus calcitriol, but not HRT alone, in both malabsorbers and normal absorbers. Osteoporosis International, 11, 43-51.
22. Horowitz, M., Wishart, J.M., Need, A.G., Morris, H.A. & Nordin, B.E.C. (1993) Effects of norethisterone on bone related biochemical variables and forearm bone mineral in postmenopausal osteoporosis. Clinical Endocrinology, 39, 649-655.
23. Joborn, C., Ljunghall, S., Larsson, K., Lindh, E., Naessen, T., Wide, L., Akerstrom, G. & Rastad, J. (1991) Skeletal responsiveness to parathyroid hormone in healthy females: relationship to menopause and oestrogen replacement. Clinical Endocrinology, 34, 335-339.
24. Kelly, P.J., Pocock, N.A., Sambrook, P.N. & Eisman, J.A. (1989) Age and menopause-related changes in indices of bone turnover. Journal of Clinical Endocrinology and Metabolism, 69, 1160-1165.
25. Khosla, S., Atkinson, E.J., Melton, L.J. & Riggs, B.L. (1997) Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: a population-based study. Journal of Clinical Endocrinology and Metabolism, 82, 1522-1527.
26. Marshall, D.H. & Nordin, B.E.C. (1969) Kinetic analysis of plasma radioactivity after oral ingestion of radiocalcium. Nature, 222, 797.
27. Minisola, S., Pacitti, M.T., Scarda, A., Rosso, R., Romagnoli, E., Garnevale, V., Scarnecchia, L. & Mazzuoli, G.F. (1993) Serum ionized calcium, parathyroid hormone and related variables, effect of age and sex. Bone and Mineral, 23, 183-193.
28. Morris, H.A., Cleghorn, D.B., Need, A.G., Horowitz, M. & Nordin, B.E.C. (1995) The 5-year reproducibility of calcium-related biochemical variables in postmenopausal women. Scandinavian Journal of Clinical and Laboratory Investigation, 55, 383-389.
29. Morris, H.A., Need, A.G., Horowitz, M., O'Loughlin, P.D. & Nordin, B.E.C. (1991) Calcium absorption in normal and osteoporotic postmenopausal women. Calcified Tissue International, 49, 240-243.
30. Need, A.G., Morris, H.A., Horowitz, M. & Nordin, B.E.C. (1997) The response to calcitriol therapy in postmenopausal osteoporotic women is a function of initial calcium absorptive status. Calcified Tissue International, 61, 6-9.
31. Need, A.G., Morris, H.A., Horowitz, M., Scopacasa, F. & Nordin, B.E.C. (1998) Intestinal calcium absorption in men with spinal osteoporosis. Clinical Endocrinology, 48, 163-168.
32. Need, A.G., Kemp, A., Giles, N., Morris, H.A., Horowitz, M. & Nordin, B.E.C. (2002) Relationships between intestinal calcium absorption, serum vitamin D metabolites and smoking in postmenopausal women. Osteoporosis International, 13, 83-88.
33. Nordin, B.E.C. (1997) Calcium and osteoporosis. Nutrition, 13, 664-686.
34. Nordin, B.E.C. (2003) Should the treatment of osteoporosis be more selective? Osteoporosis International, 14, 99-102.
35. Nordin, B.E.C. & Polley, K.J. (1987) Metabolic consequences of the menopause. A cross-sectional, longitudinal, and intervention study on 557 normal postmenopausal women. Calcified Tissue International, 41, S1-S60.
36. Nordin, B.E.C., Horsman, A. & Aaron, J. (1976) Diagnostic procedures. In: Calcium, Phosphate and Magnesium Metabolism (ed. B. E. C. Nordin), pp. 469-525. Churchill Livingstone, Edinburgh.
37. 2D levels in postmenopausal osteoporosis. In: Vitamin D Basic Research and its Clinical Application (eds A. W. Norman, K. Schaefer, H. -T. Grigoleit & Dv. Herrath), pp. 382-387. Elsevier, New York.
38. Nordin, B.E.C., Need, A.G., Hartley, T.F., Philcox, J.C., Wilcox, M. & &. Thomas, D.W. (1989) Improved method for calculating calcium fractions in plasma: reference values and effect of menopause. Clinical Chemistry 35, 14-17; Erratum 35, 670.
39. Nordin, B.E.C., Morris, H.A., Wishart, J.M., Scopacasa, F., Horowitz, M. &. Need, A.G. & Clifton, P.M. (1998) Modification and validation of a single-isotope radiocalcium absorption test. Journal of Nuclear Medicine, 39, 108-113.
40. Nordin, B.E.C., Need, A.G., Morris, H.A. & Horowitz, M. (1999) Biochemical variables in pre- and postmenopausal women reconciling the calcium and estrogen hypotheses. Osteoporosis International, 9, 351-357.
41. Orr-Walker, B.J., Home, A.M., Evans, M.C., Grey, A.B., Murray, M.A.F., McNeil, A.R. & Reid, I.R. (1999) Hormone replacement therapy causes a respiratory alkalosis in normal postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 84, 1997-2001.
42. Prince, R.L. (1994) Counterpoint: Estrogen effects on calcitropic hormones and calcium homeostasis. Endocrine Reviews, 15, 301-309.
43. Prince, R.L., Schiff, I. & Neer, R.M. (1990) Effects of transdermal estrogen replacement on parathyroid hormone secretion. Journal of Clinical Endocrinology and Metabolism, 71, 1284-1287.
44. Recker, R., Lappe, J., Davies, K. & Heaney, R. (2000) Characterization of perimenopausal bone loss: a prospective study. Journal of Bone and Mineral Research, 15, 1965-1973.
45. Riggs, B.L., Khosla, S. & Melton, L.J. (1998) A unitary model for involutional osteoporosis, estrogen deficiency causes both Type I and Type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. Journal of Bone and Mineral Research, 13, 763-773.
46. Scopacasa, F., Horowitz, M., Wishart, J., Need, A.G., Morris, H.A., Wittert, G. & Nordin, B.E.C. (1998) Calcium supplementation suppresses bone resorption in early postmenopausal women. Calcified Tissue International, 62, 8-12.
47. Selby, P.L. & Peacock, M. (1986a) Ethinyl estradiol and norethindrone in the treatment of primary hyperparathyroidism in postmenopausal women. New England Journal of Medicine, 314, 1481-1485.
48. Selby, P.L. & Peacock, M. (1986b) The effect of transdermal oestrogen on bone, calcium-regulating hormones and liver in postmenopausal women. Clinical Endocrinology, 25, 543-547.
49. Selby, P.L., Peacock, M., Barkworth, S.A., Brown, W.B. & Taylor, G.A. (1985) Early effects of ethinyloestradiol and norethisterone treatment in post-menopausal women on bone resorption and calcium regulation hormones. Clinical Science, 69, 265-271.
50. Stepan, J.J., Pospichal, J., Presl, J. & Pacovsky, V. (1987) Bone loss and biochemical indices of bone remodeling in surgically induced postmenopausal women. Bone, 8, 279-284.
51. Wishart, J.M., Scopacasa, F., Horowitz, M., Morris, H.A., Need, A.G., Clifton, P.M. & Nordin, B.E.C. (2000) Effect of perimenopause on calcium absorption: a longitudinal study. Climacteric, 3, 102-108.
52. Young, M.M. & Nordin, B.E.C. (1967) Effects of natural and artificial menopause on plasma and urinary calcium and phosphorus. Lancet, 2, 118 -120.