Impact of female cigarette smoking on circulating B cells in vivo: The suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function

Immunogenetics

Volumn 62, Issue 4, 2010, Pages 237-251

  Pan, Feng ^a,b   Yang, Tie Lin ^a,c   Chen, Xiang Ding ^b,d   Chen, Yuan ^a,b   Gao, Ge ^b   Liu, Yao Zhong ^c   Pei, Yu Fang ^a,c   Sha, Bao Yong ^a,b   Jiang, Yan ^e   Xu, Chao ^e   Recker, Robert R ^b   Deng, Hong Wen ^a,c,d,e  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^d HUNAN NORMAL UNIVERSITY   (China)

^e UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY   (China)

Author keywords

Association; B cells; Cigarette smoking; Genome wide; Microarray

Indexed keywords

CELL PROTEIN; CHEMOKINE RECEPTOR CCR1; GENOMIC DNA; INDUCIBLE T CELL COSTIMULATOR LIGAND; INTERLEUKIN 13; T CELL FACTOR 3 PROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ICOSLG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; MESSENGER RNA; TCF3 PROTEIN, HUMAN;

ADULT; ARTICLE; B LYMPHOCYTE; CAUCASIAN; CIGARETTE SMOKING; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC ASSOCIATION; GENOME ANALYSIS; GENOTYPE; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MICROARRAY ANALYSIS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; DNA MICROARRAY; GENE REGULATORY NETWORK; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; SMOKING;

ADULT; ANTIGENS, CD; B-LYMPHOCYTES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SMOKING; VASCULAR CELL ADHESION MOLECULE-1;

EID: 77950597627     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-010-0431-6     Document Type: Article

References (80)

1. AJ Alberg JG Ford JM Samet 2007 Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition) Chest 132 3 Suppl 29S 55S 10.1378/chest.07-1347 1:CAS:528:DC%2BD2sXht1amt7jN 17873159 (Pubitemid 47494394)
2. HS Al-Ghamdi S Anil 2007 Serum antibody levels in smoker and non-smoker Saudi subjects with chronic periodontitis J Periodontol 78 6 1043 1050 10.1902/jop.2007.060431 17539718
3. A Amos 1996 Women and smoking Br Med Bull 52 1 74 89 1:STN:280: DyaK28zmt1elsA%3D%3D 8746298 (Pubitemid 26039050)
4. SE Barbour K Nakashima JB Zhang S Tangada CL Hahn HA Schenkein JG Tew 1997 Tobacco and smoking: environmental factors that modify the host response (immune system) and have an impact on periodontal health Crit Rev Oral Biol Med 8 4 437 460 10.1177/10454411970080040501 1:STN:280:DyaK1c%2FltlansA%3D%3D 9391754 (Pubitemid 28123817)
5. Y Benjamini Y Hochberg 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing J R Statist Soc B 57 1 289 300
6. AW Bergen N Caporaso 1999 Cigarette smoking J Natl Cancer Inst 91 16 1365 1375 10.1093/jnci/91.16.1365 1:STN:280:DyaK1Mzot1ekug%3D%3D 10451441 (Pubitemid 29399994)
7. CH Bosken J Hards K Gatter JC Hogg 1992 Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry Am Rev Respir Dis 145 4 Pt 1 911 917 1:STN:280: DyaK383gs1Olsg%3D%3D 1554220
8. C Bradney M Hjelmeland Y Komatsu M Yoshida TP Yao Y Zhuang 2003 Regulation of E2A activities by histone acetyltransferases in B lymphocyte development J Biol Chem 278 4 2370 2376 10.1074/jbc.M211464200 1:CAS:528:DC%2BD3sXksFagsQ%3D%3D 12435739 (Pubitemid 36801309)
9. CA Brandsma MN Hylkema BW van der Strate DJ Slebos MA Luinge M Geerlings W Timens DS Postma HA Kerstjens 2008 Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells? Respir Res 9 17 10.1186/1465-9921-9-17 18252008
10. K Briegel KC Lim C Plank H Beug JD Engel M Zenke 1993 Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner Genes Dev 7 6 1097 1109 10.1101/gad.7.6.1097 1:CAS:528:DyaK3sXkvVKmu7Y%3D 8504932 (Pubitemid 23170832)
11. P Buttner S Mosig H Funke 2007 Gene expression profiles of T lymphocytes are sensitive to the influence of heavy smoking: a pilot study Immunogenetics 59 1 37 43 10.1007/s00251-006-0177-3 17149619 (Pubitemid 46011190)
12. Y Cavusoglu B Timuralp T Us Y Akgun G Kudaiberdieva B Gorenek A Unalir O Goktekin N Ata 2004 Cigarette smoking increases plasma concentrations of vascular cell adhesion molecule-1 in patients with coronary artery disease Angiology 55 4 397 402 10.1177/000331970405500406 15258685 (Pubitemid 38924369)
13. MA Chan SH Benedict KC Carstairs WH Francombe EW Gelfand 1990 Expansion of B lymphocytes with an unusual immunoglobulin rearrangement associated with atypical lymphocytosis and cigarette smoking Am J Respir Cell Mol Biol 2 6 549 552 1:CAS:528:DyaK3MXmtVSqtLY%3D 2346660
14. P Cirillo M Pacileo S De Rosa P Calabro A Gargiulo V Angri N Prevete I Fiorentino G Ucci L Sasso G Petrillo SM D'Amore M Chiariello 2007 HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells J Vasc Res 44 6 460 470 10.1159/000106464 1:CAS:528:DC%2BD2sXht1ShurbN 17657162 (Pubitemid 350022320)
15. I Cloez-Tayarani JP Changeux 2007 Nicotine and serotonin in immune regulation and inflammatory processes: a perspective J Leukoc Biol 81 3 599 606 10.1189/jlb.0906544 1:CAS:528:DC%2BD2sXisFCmsbo%3D 17108054 (Pubitemid 46393537)
16. BG Cocks MR de Waal JP Galizzi JE de Vries G Aversa 1993 IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand Int Immunol 5 6 657 663 10.1093/intimm/5.6.657 1:CAS:528:DyaK2cXivFSmsg%3D%3D 7688562 (Pubitemid 23209420)
17. A Corcione G Tortolina R Bonecchi N Battilana G Taborelli F Malavasi S Sozzani L Ottonello F Dallegri V Pistoia 2002 Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells Int Immunol 14 8 883 892 10.1093/intimm/dxf054 1:CAS:528:DC%2BD38XmsVKjtbo%3D 12147625
18. W Cozen D Diaz-Sanchez W James Gauderman J Zadnick MG Cockburn PS Gill R Masood AS Hamilton M Jyrala TM Mack 2004 Th1 and Th2 cytokines and IgE levels in identical twins with varying levels of cigarette consumption J Clin Immunol 24 6 617 622 10.1007/s10875-004-6247-0 1:CAS:528:DC%2BD2MXhtFSnsQ%3D%3D 15622446 (Pubitemid 40933113)
19. T Defrance P Carayon G Billian JC Guillemot A Minty D Caput P Ferrara 1994 Interleukin 13 is a B cell stimulating factor J Exp Med 179 1 135 143 10.1084/jem.179.1.135 1:CAS:528:DyaK2cXnsFWlsg%3D%3D 7903680 (Pubitemid 24012978)
20. B Devlin K Roeder 1999 Genomic control for association studies Biometrics 55 4 997 1004 10.1111/j.0006-341X.1999.00997.x 1:STN:280:DC%2BD3M3itFSqtA%3D%3D 11315092
21. GR Ehrhardt JT Hsu L Gartland CM Leu S Zhang RS Davis MD Cooper 2005 Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells J Exp Med 202 6 783 791 10.1084/jem.20050879 1:CAS:528:DC%2BD2MXhtVegsLjK 16157685 (Pubitemid 41345967)
22. MB Eisen PT Spellman PO Brown D Botstein 1998 Cluster analysis and display of genome-wide expression patterns Proc Natl Acad Sci U S A 95 25 14863 14868 10.1073/pnas.95.25.14863 1:CAS:528:DyaK1cXotVGmurk%3D 9843981 (Pubitemid 29003722)
23. W Feleszko A Zawadzka-Krajewska K Matysiak D Lewandowska J Peradzynska QT Dinh E Hamelmann DA Groneberg M Kulus 2006 Parental tobacco smoking is associated with augmented IL-13 secretion in children with allergic asthma J Allergy Clin Immunol 117 1 97 102 10.1016/j.jaci.2005.09.008 1:CAS:528:DC%2BD28Xktlak 16387591 (Pubitemid 43017146)
24. SR Frank MR Adelstein SH Hansen 2006 GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover Embo J 25 9 1848 1859 10.1038/sj.emboj.7601092 1:CAS:528:DC%2BD28XktVGmsb0%3D 16628223
25. D Frasca AM Landin SC Lechner JG Ryan R Schwartz RL Riley BB Blomberg 2008 Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells J Immunol 180 8 5283 5290 1:CAS:528:DC%2BD1cXkt1arsLg%3D 18390709
26. PE Funk PW Kincade PL Witte 1994 Native associations of early hematopoietic stem cells and stromal cells isolated in bone marrow cell aggregates Blood 83 2 361 369 1:STN:280:DyaK2c7hsV2itg%3D%3D 7506947
27. S Gandini E Botteri S Iodice M Boniol AB Lowenfels P Maisonneuve P Boyle 2008 Tobacco smoking and cancer: a meta-analysis Int J Cancer 122 1 155 164 10.1002/ijc.23033 1:CAS:528:DC%2BD2sXhsVSgtbrF 17893872 (Pubitemid 350209990)
28. Y Geng SM Savage LJ Johnson J Seagrave ML Sopori 1995 Effects of nicotine on the immune response. I. Chronic exposure to nicotine impairs antigen receptor-mediated signal transduction in lymphocytes Toxicol Appl Pharmacol 135 2 268 278 10.1006/taap.1995.1233 1:CAS:528:DyaK28XhvFSnsQ%3D%3D 8545837 (Pubitemid 26031878)
29. G Getz E Levine E Domany 2000 Coupled two-way clustering analysis of gene microarray data Proc Natl Acad Sci U S A 97 22 12079 12084 10.1073/pnas. 210134797 1:CAS:528:DC%2BD3cXnvVSgtL4%3D 11035779
30. R Gisler M Sigvardsson 2002 The human V-preB promoter is a target for coordinated activation by early B cell factor and E47 J Immunol 168 10 5130 5138 1:CAS:528:DC%2BD38XjslSjt7k%3D 11994467 (Pubitemid 34495978)
31. TR Golub DK Slonim P Tamayo C Huard M Gaasenbeek JP Mesirov H Coller ML Loh JR Downing MA Caligiuri CD Bloomfield ES Lander 1999 Molecular classification of cancer: class discovery and class prediction by gene expression monitoring Science 286 5439 531 537 10.1126/science.286.5439.531 1:CAS:528:DyaK1MXmvVOhu7g%3D 10521349
32. S Greenbaum AS Lazorchak Y Zhuang 2004 Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes J Biol Chem 279 43 45028 45035 10.1074/jbc.M400061200 1:CAS:528:DC%2BD2cXosFymu7c%3D 15310760 (Pubitemid 39430917)
33. Hasnis E, Bar-Shai M, Burbea Z, Reznick AZ (2007) Cigarette smoke-induced NF-kappaB activation in human lymphocytes: the effect of low and high exposure to gas phase of cigarette smoke. J Physiol Pharmacol 58 (Suppl 5, Pt 1):263-274. (Pubitemid 351346673)
34. CI Henschke R Yip OS Miettinen 2006 Women's susceptibility to tobacco carcinogens and survival after diagnosis of lung cancer Jama 296 2 180 184 10.1001/jama.296.2.180 16835423 (Pubitemid 44050371)
35. W Hu A Janke S Ortler HP Hartung C Leder BC Kieseier H Wiendl 2007 Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies Neurology 68 4 277 282 10.1212/01.wnl.0000250240.99311.9d 1:CAS:528:DC%2BD2sXlt12msA%3D%3D 17242332 (Pubitemid 46148339)
36. A Hutloff K Buchner K Reiter HJ Baelde M Odendahl A Jacobi T Dorner RA Kroczek 2004 Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus Arthritis Rheum 50 10 3211 3220 10.1002/art.20519 15476242 (Pubitemid 39371998)
37. RA Irizarry B Hobbs F Collin YD Beazer-Barclay KJ Antonellis U Scherf TP Speed 2003 Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 4 2 249 264 10.1093/biostatistics/4.2.249 12925520
38. JC Kidney AG Wong A Efthimiadis MM Morris MR Sears J Dolovich FE Hargreave 1996 Elevated B cells in sputum of asthmatics. Close correlation with eosinophils Am J Respir Crit Care Med 153 2 540 544 1:STN:280: DyaK287mtVGlsg%3D%3D 8564094 (Pubitemid 26051326)
39. M Kraft KB Adler JL Ingram AL Crews TP Atkinson CB Cairns DC Krause HW Chu 2008 Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma Eur Respir J 31 1 43 46 10.1183/09031936.00103307 1:STN:280:DC%2BD1c%2FgsVSnsA%3D%3D 18166592
40. A Langhammer R Johnsen J Holmen A Gulsvik L Bjermer 2000 Cigarette smoking gives more respiratory symptoms among women than among men. The Nord-Trondelag Health Study (HUNT) J Epidemiol Community Health 54 12 917 922 10.1136/jech.54.12.917 1:STN:280:DC%2BD3M7htFKiuw%3D%3D 11076988
41. JS Lee MR Rosengart V Kondragunta Y Zhang J McMurray RA Branch AM Choi FC Sciurba 2007 Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study Respir Res 8 64 10.1186/1465-9921-8-64 17868461
42. SF Lei S Wu LM Li FY Deng SM Xiao C Jiang Y Chen H Jiang F Yang LJ Tan X Sun XZ Zhu MY Liu YZ Liu XD Chen HW Deng 2009 An in vivo genome wide gene expression study of circulating monocytes suggested GBP1, STAT1 and CXCL10 as novel risk genes for the differentiation of peak bone mass Bone 44 5 1010 1014 10.1016/j.bone.2008.05.016 1:CAS:528:DC%2BD1MXktFags7k%3D 19223260
43. C Li W Hung Wong 2001 Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application Genome Biol 2 8 RESEARCH0032 1:CAS:528:DC%2BD38XitlahsLg%3D 11532216
44. C Li WH Wong 2001 Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection Proc Natl Acad Sci U S A 98 1 31 36 10.1073/pnas.011404098 1:CAS:528:DC%2BD3MXkslKnuw%3D%3D 11134512 (Pubitemid 32095858)
45. YZ Liu V Dvornyk Y Lu H Shen JM Lappe RR Recker HW Deng 2005 A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes J Biol Chem 280 32 29011 29016 10.1074/jbc.M501164200 1:CAS:528:DC%2BD2MXntVegsrk%3D 15965235 (Pubitemid 41161349)
46. YZ Liu YF Pei YF Guo L Wang XG Liu H Yan DH Xiong YP Zhang S Levy J Li CK Haddock CJ Papasian Q Xu JZ Ma TJ Payne RR Recker MD Li HW Deng 2009 Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15 Mol Psychiatry 14 7 668 680 10.1038/mp.2009.3 1:CAS:528:DC%2BD1MXnsFers7o%3D 19188921
47. XG Liu LJ Tan SF Lei YJ Liu H Shen L Wang H Yan YF Guo DH Xiong XD Chen F Pan TL Yang YP Zhang Y Guo NL Tang XZ Zhu HY Deng S Levy RR Recker CJ Papasian HW Deng 2009 Genome-wide association and replication studies identified TRHR as an important gene for lean body mass Am J Hum Genet 84 3 418 423 10.1016/j.ajhg.2009.02.004 1:CAS:528:DC%2BD1MXmvFCls74%3D 19268274
48. YZ Liu YF Guo L Wang LJ Tan XG Liu YF Pei H Yan DH Xiong FY Deng N Yu YP Zhang L Zhang SF Lei XD Chen HB Liu XZ Zhu S Levy CJ Papasian BM Drees JJ Hamilton RR Recker HW Deng 2009 Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche PLoS Genet 5 3 e1000420 10.1371/journal.pgen.1000420 19282985
49. J Mackay A Amos 2003 Women and tobacco Respirology 8 2 123 130 10.1046/j.1440-1843.2003.00464.x 12753525 (Pubitemid 36749692)
50. L Marshall M Schooley H Ryan P Cox A Easton C Healton K Jackson KC Davis G Homsi 2006 Youth tobacco surveillance-United States, 2001-2002 MMWR Surveill Summ 55 3 1 56 16708059
51. AN McKenzie JA Culpepper MR de Waal F Briere J Punnonen G Aversa A Sato W Dang BG Cocks S Menon, et al. 1993 Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function Proc Natl Acad Sci U S A 90 8 3735 3739 10.1073/pnas.90.8.3735 1:CAS:528:DyaK3sXktVKqt7w%3D 8097324 (Pubitemid 23111442)
52. RE Mebius 2003 Organogenesis of lymphoid tissues Nat Rev Immunol 3 4 292 303 10.1038/nri1054 1:CAS:528:DC%2BD3sXisFWkurc%3D 12669020
53. P Moszczynski Z Zabinski P Moszczynski Jr J Rutowski S Slowinski Z Tabarowski 2001 Immunological findings in cigarette smokers Toxicol Lett 118 3 121 127 10.1016/S0378-4274(00)00270-8 1:CAS:528:DC%2BD3MXptVSlsw%3D%3D 11137318 (Pubitemid 32008403)
54. AM Murrell AR Green 1995 Regulation of lineage restricted haemopoietic transcription factors in cell hybrids Oncogene 10 4 631 639 1:CAS:528: DyaK2MXktF2lsLk%3D 7862440
55. I Nakao S Kanaji S Ohta H Matsushita K Arima N Yuyama M Yamaya K Nakayama H Kubo M Watanabe H Sagara K Sugiyama H Tanaka S Toda H Hayashi H Inoue T Hoshino A Shiraki M Inoue K Suzuki H Aizawa S Okinami H Nagai M Hasegawa T Fukuda ED Green K Izuhara 2008 Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease J Immunol 180 9 6262 6269 1:CAS:528:DC%2BD1cXkvVCjt74%3D 18424749
56. D Noda T Hamachi K Inoue K Maeda 2007 Relationship between the presence of periodontopathic bacteria and the expression of chemokine receptor mRNA in inflamed gingival tissues J Periodontal Res 42 6 566 571 10.1111/j.1600-0765. 2007.00984.x 1:CAS:528:DC%2BD2sXhsVelur7O 17956471
57. J Parkin B Cohen 2001 An overview of the immune system Lancet 357 9270 1777 1789 10.1016/S0140-6736(00)04904-7 1:CAS:528:DC%2BD3MXkt1Khsrc%3D 11403834 (Pubitemid 32524226)
58. JK Pritchard M Stephens P Donnelly 2000 Inference of population structure using multilocus genotype data Genetics 155 2 945 959 1:STN:280: DC%2BD3cvislKrtA%3D%3D 10835412 (Pubitemid 30397141)
59. O Regius K Rajczy I Gergely L Borzsonyi E Lengyel P Vargha 1990 The effect of smoking on peripheral blood lymphocytes and on some immunological parameters in old age Z Gerontol 23 3 163 167 1:STN:280:DyaK3czmsVOntg%3D%3D 2392875 (Pubitemid 20264850)
60. MI Ryder W Hyun P Loomer C Haqq 2004 Alteration of gene expression profiles of peripheral mononuclear blood cells by tobacco smoke: implications for periodontal diseases Oral Microbiol Immunol 19 1 39 49 10.1046/j.0902-0055. 2003.00110.x 1:CAS:528:DC%2BD2cXhs1Wltbg%3D 14678473 (Pubitemid 38101503)
61. A Sadeghnejad DA Meyers M Bottai DA Sterling ER Bleecker JA Ohar 2007 IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function Am J Respir Crit Care Med 176 8 748 752 10.1164/rccm.200704-543OC 1:CAS:528:DC%2BD2sXhtleru77J 17615386 (Pubitemid 47598475)
62. A Sadeghnejad W Karmaus SH Arshad R Kurukulaaratchy M Huebner S Ewart 2008 IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study Respir Res 9 2 10.1186/1465-9921-9-2 18186920
63. SM Savage LA Donaldson S Cherian R Chilukuri VA White ML Sopori 1991 Effects of cigarette smoke on the immune response. II. Chronic exposure to cigarette smoke inhibits surface immunoglobulin-mediated responses in B cells Toxicol Appl Pharmacol 111 3 523 529 10.1016/0041-008X(91)90256-E 1:CAS:528:DyaK38XnvVentQ%3D%3D 1746027
64. M Sironi FL Sciacca C Matteucci M Conni A Vecchi S Bernasconi A Minty D Caput P Ferrara F Colotta, et al. 1994 Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production Blood 84 6 1913 1921 1:CAS:528:DyaK2cXmt1ynsrw%3D 7521694
65. MV Skok EN Kalashnik LN Koval VI Tsetlin YN Utkin JP Changeux R Grailhe 2003 Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines Mol Pharmacol 64 4 885 889 10.1124/mol.64.4.885 1:CAS:528:DC%2BD3sXnslGrurY%3D 14500745 (Pubitemid 37153057)
66. M Skok R Grailhe JP Changeux 2005 Nicotinic receptors regulate B lymphocyte activation and immune response Eur J Pharmacol 517 3 246 251 10.1016/j.ejphar.2005.05.011 1:CAS:528:DC%2BD2MXmtFGitr0%3D 15963492 (Pubitemid 40977902)
67. MV Skok R Grailhe F Agenes JP Changeux 2007 The role of nicotinic receptors in B-lymphocyte development and activation Life Sci 80 24-25 2334 2336 10.1016/j.lfs.2007.02.005 1:CAS:528:DC%2BD2sXmtVehtLs%3D 17363009 (Pubitemid 46818278)
68. M Tsoumakidou W Elston J Zhu Z Wang E Gamble NM Siafakas NC Barnes PK Jeffery 2007 Cigarette smoking alters bronchial mucosal immunity in asthma Am J Respir Crit Care Med 175 9 919 925 10.1164/rccm.200607-908OC 1:CAS:528:DC%2BD2sXls12ru7s%3D 17303795 (Pubitemid 46684702)
69. BW van der Strate DS Postma CA Brandsma BN Melgert MA Luinge M Geerlings MN Hylkema A van den Berg W Timens HA Kerstjens 2006 Cigarette smoke-induced emphysema: a role for the B cell? Am J Respir Crit Care Med 173 7 751 758 10.1164/rccm.200504-594OC 16399994
70. DM van Leeuwen RW Gottschalk MH van Herwijnen EJ Moonen JC Kleinjans JH van Delft 2005 Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents Toxicol Sci 86 1 200 210 10.1093/toxsci/kfi168 15829617 (Pubitemid 41511365)
71. DM van Leeuwen E van Agen RW Gottschalk R Vlietinck M Gielen MH van Herwijnen LM Maas JC Kleinjans JH van Delft 2007 Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs Carcinogenesis 28 3 691 697 10.1093/carcin/bgl199 17056606 (Pubitemid 46523366)
72. S Vignes E Oksenhendler L Quint MT Daniel X Mariette JP Clauvel 2000 Polyclonal B lymphocytosis and hyper-IgM: immunodeficiency and/or benign lymphoid proliferation associated with tobacco? Rev Med Interne 21 3 236 241 10.1016/S0248-8663(00)80042-9 1:STN:280:DC%2BD3c3is1eqtg%3D%3D 10763184 (Pubitemid 30434088)
73. C von Mering LJ Jensen B Snel SD Hooper M Krupp M Foglierini N Jouffre MA Huynen P Bork 2005 STRING: known and predicted protein-protein associations, integrated and transferred across organisms Nucleic Acids Res 33 Database issue D433 D437 10.1093/nar/gki005 (Pubitemid 40207910)
74. X Wu TG Dewey 2006 From microarray to biological networks: analysis of gene expression profiles Methods Mol Biol 316 35 48 16671399
75. Z Wu RA Irizarry R Gentleman F Martinez-Murillo F Spencer 2004 A model-based background adjustment for oligonucleotide expression arrays J Am Stat Assoc 99 468 909 917 10.1198/016214504000000683 (Pubitemid 39665934)
76. TA Wynn 2003 IL-13 effector functions Annu Rev Immunol 21 425 456 10.1146/annurev.immunol.21.120601.141142 1:CAS:528:DC%2BD3sXjtF2isrY%3D 12615888 (Pubitemid 37174537)
77. DH Xiong XG Liu YF Guo LJ Tan L Wang BY Sha ZH Tang F Pan TL Yang XD Chen SF Lei LM Yerges XZ Zhu VW Wheeler AL Patrick CH Bunker Y Guo H Yan YF Pei YP Zhang S Levy CJ Papasian P Xiao YW Lundberg RR Recker YZ Liu YJ Liu JM Zmuda HW Deng 2009 Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups Am J Hum Genet 84 3 388 398 10.1016/j.ajhg.2009.01.025 1:CAS:528: DC%2BD1MXmvFClsrg%3D 19249006
78. CZ Yang H Heimberg C D'Souza-Schorey MM Mueckler PD Stahl 1998 Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells J Biol Chem 273 7 4006 4011 10.1074/jbc.273.7.4006 1:CAS:528:DyaK1cXht1ahsrY%3D 9461590 (Pubitemid 28103264)
79. Q Yang M Hergenhahn A Weninger H Bartsch 1999 Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji Carcinogenesis 20 9 1769 1775 10.1093/carcin/20.9.1769 1:CAS:528:DyaK1MXlvFWqsbk%3D 10469623 (Pubitemid 29410557)
80. T Zheng Z Zhu Z Wang RJ Homer B Ma RJ Riese Jr HA Chapman Jr SD Shapiro JA Elias 2000 Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema J Clin Invest 106 9 1081 1093 10.1172/JCI10458 1:CAS:528:DC%2BD3cXnvFyqtbg%3D 11067861