Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji

Carcinogenesis

Volumn 20, Issue 9, 1999, Pages 1769-1775

  Yang, Q ^a   Hergenhahn, M ^a   Weninger, A ^a   Bartsch, H ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ACETYLCYSTEINE; ACROLEIN; ASCORBIC ACID; BETA NAPHTHOFLAVONE; BROXURIDINE; CIGARETTE SMOKE; COUMARIN; CYTOCHROME P450 ISOENZYME; DNA; ETHOXYRESORUFIN DEETHYLASE; FORMALDEHYDE; OXYGENASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA SYNTHESIS INHIBITION; GAMMA RADIATION; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; LYMPHOID CELL; MICROELECTROPHORESIS; PRIORITY JOURNAL; RAJI CELL;

ACETALDEHYDE; ACETYLCYSTEINE; ACROLEIN; ALDEHYDES; ARYL HYDROCARBON HYDROXYLASES; ASCORBIC ACID; B-LYMPHOCYTES; BETA-NAPHTHOFLAVONE; BIOTRANSFORMATION; BURKITT LYMPHOMA; COUMARINS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; DNA DAMAGE; DNA REPAIR; DNA, NEOPLASM; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; FORMALDEHYDE; FREE RADICAL SCAVENGERS; GAMMA RAYS; HUMANS; MIXED FUNCTION OXYGENASES; N-GLYCOSYL HYDROLASES; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; SMOKE;

EID: 0032870878     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.9.1769     Document Type: Article

References (44)

1. International Agency for Research on Cancer (1986) Tobacco Smoking. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Vol. 38. IARC Scientific Publications, IARC, Lyon.
2. Hecht, S.S. and Hoffmann, D. (1988) Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco-smoke. Carcinogenesis, 9, 875-884.
3. Fischer, S., Spiegelhalder, B. and Preussmann, R. (1991) Tobacco-specific nitrosamines in commercial cigarettes: possibilities for reducing exposure. IARC Scientific Publications No. 105, pp. 489-492.
4. Grafström, R.C., Curren, R.D., Yang, L.L. and Harris, C.C. (1986) Aldehyde-induced inhibition of DNA repair and potentiation of N-nitroso compound-induced mutagenesis in cultured human cells. Prog. Clin. Biol. Res., 209A, 255-264.
5. Dypbukt, J.M., Atzori, L., Edman, C.C. and Grafström, R.C. (1993) Thiol status and cytopathological effects of acrolein in normal and xeroderma pigmentosum skin fibroblasts. Carcinogenesis, 14, 975-980.
6. Eisenbrand, G., Schuhmacher, J. and Gölzer, P. (1995) The influence of glutathione and detoxifying enzymes on DNA damage induced by 2-alkenals in primary rat hepatocytes and human lymphoblastoid cells. Chem. Res. Toxicol., 8, 40-46.
7. Pryor, W.A. (1992) Biological effects of cigarette smoke, wood smoke and the smoke from plastics: the use of electron spin resonance. Free Radical Biol. Med., 13, 659-676.
8. Kodama, M., Kaneko, M., Aida, M., Inoue, F., Nakayama, T. and Akimoto, H. (1997) Free radical chemistry of cigarette smoke and its implication in human cancer. Anticancer Res., 17, 433-438.
9. Yoshie, Y. and Ohshima, H. (1997) Synergistic induction of DNA strand breakage by cigarette tar and nitric oxide. Carcinogenesis, 18, 1359-1363.
10. Müller, T., Haussmann, H.J. and Schepers, G. (1997) Evidence for peroxynitrite as an oxidative stress-inducing compound of aqueous cigarette smoke fractions. Carcinogenesis, 18, 295-301.
11. Prevost, V. and Shuker, D.E.G. (1996) Cigarette smoking and urinary 3-alkyladenine excretion in man. Chem. Res. Toxicol., 9, 439-444.
12. Kopplin, A., Eberle-Adamkiewicz, G., Glüsenkamp, K.-H., Nehls, P. and Kirstein, U. (1995) Urinary excretion of 3-methyladenine and 3-ethyladenine after controlled exposure to tobacco smoke. Carcinogenesis, 16, 2637-2641.
13. 32P-post-labeling. Comparison with cigarette smoke-associated DNA adduct profiles in vivo. Mutat. Res., 268, 139-153.
14. Van Dyke, D.L., Worsham, M.J., Benninger, M.S., Krause, C.J., Baker, S.R., Wolf, G.T., Drumheller, T., Tilley, B.C. and Carey, T.E. (1994) Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region. Genes Chrom. Cancer, 9, 192-206.
15. Stone, J.G., Jones, N.J., McGregor, A.D. and Waters, R. (1995) Development of a human biomonitoring assay using buccal mucosa: comparison of smoking-related DNA adducts in mucosa versus biopsies. Cancer Res., 55, 1267-1270.
16. Zhang, Y.J., Hsu, T.M. and Santella, R.M. (1995) Immunoperoxidase detection of polycyclic aromatic hydrocarbon-DNA adducts in oral mucosa of smokers and nonsmokers. Cancer Epidemiol. Biomarkers Prev., 4, 133-138.
17. DeMarini, D.M., Shelton, M.L. and Levine, J.G. (1995) Mutation spectrum of cigarette smoke condensate in Salmonella: comparison with mutations in smoking-associated tumors. Carcinogenesis, 16, 2535-2542.
18. Yang, Q., Hergenhahn, M. and Bartsch, H. (1997) Epstein-Barr virus episomes as target for cigarette smoke- and γ-irradiation-induced DNA damage: studies on the EBNA-1 region by a new gene-specific technique. Carcinogenesis, 18, 1401-1405.
19. Liu, Y., Sundqvist, K., Belinsky, S.A., Castonguay, A., Tjalve, H. and Grafström, R.C. (1993) Metabolism and macromolecular interaction of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in cultured explants and epithelial cells of human buccal mucosa. Carcinogenesis, 14, 2383-2388.
20. Reiners, J.J., Cantu, A.R., Pavone, A., Smith, S.C., Gardner, C.R. and Laskin, D.L. (1990) Fluorescence assay for per-cell estimation of cytochrome P-450-dependent monooxygenase activities in keratinocyte suspensions and cultures. Anal. Biochem., 188, 317-324.
21. Wattenberg, L.W. (1980) Inhibitors of chemical carcinogens. J. Environ. Pathol. Toxicol., 3, 35-52.
22. Määnpaa, J., Juvonen, R., Raunio, H., Rautio, A. and Pelkonen, O. (1994) Metabolic interactions of methoxysalen and coumarin in humans and mice. Biochem. Pharmacol., 48, 1363-1369.
23. Yamazaki, H., Inui, Y., Yun, C.H., Guengerich, F.P. and Shimada, T. (1992) Cytochrome P450 2E1 and 2A6 as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis, 13, 1789-1794.
24. McKelvey-Martin, V.J., Green, M.H., Schmezer, P., Pool-Zobel, B.L., de Meo, M.P. and Collins, A. (1993) The single cell gel electrophoresis assay (comet assay): a European review, Mutat. Res., 288, 47-63.
25. Pool-Zobel, B.L., Lotzmann, N., Knoll, M., Kuchenmeister, F., Lambertz, R., Leucht, U., Schröder, H.-G. and Schmezer, P. (1994) Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples. Environ. Mol. Mutagen., 24, 23-45.
26. Dolbeare, F., Beisker, W., Pallavicini, M.G., Vanderlaan, M. and Gray, J.W. (1985) Cytochemistry for bromodeoxyuridine analysis: stoichiometry and sensitivity. Cytometry, 6, 521-530.
27. Nash, H.M., Lu, R.-Z., Lane, W.S. and Verdine, G.L. (1997) The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution. Chem. Biol., 4, 693-702.
28. Sopta, M., Carthew, R.W. and Greenblatt, J. (1985) Isolation of three proteins that bind to mammalian RNA polymerase II. J. Biol. Chem., 260, 10353-10360.
29. Collins, A.R., Dobson, V.L., Dusinska, M., Kennedy, G. and Stetina, R. (1997) The comet assay: what can it really tell us? Mutat. Res., 375, 183-193.
30. Nackerdien, Z., Olinski, R. and Dizdaroglu, M. (1992) DNA base damage in chromatin of gamma-irradiated cultured human cells. Free Radical Res. Commun., 16, 259-273.
31. Karahalil, B., Girard, P.M., Boiteux, S. and Dizdaroglu, M. (1998) Substrate specificity of the Ogg1 protein of Saccharomyces cerevisiae: excision of guanine lesions produced in DNA by ionizing radiation-or hydrogen peroxide/metal ion-generated free radicals. Nucleic Acids Res., 26, 1228-1233.
32. Uchida, K., Kanematsu, M., Sakai, K., Matsuda, T, Hattori, N., Mizuno, Y., Suzuki, D., Miyata, T., Noguchi, N., Niki, E. and Osawa, T. (1998) Protein-bound acrolein: potential markers for oxidative stress. Proc. Natl Acad. Sci. USA, 95, 4882-4887.
33. Matsukura, N., Willey, J., Miyashita, M., Taffe, B., Hoffmann, D., Waldren, C., Puck, T.T. and Harris, C.C. (1991) Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells. Carcinogenesis, 12, 685-689.
34. Stich, H.F., Karim, J., Koropatnick, J. and Lo, L. (1976) Mutagenic action of ascorbic acid. Nature, 260, 722-724.
35. Anderson, D., Yu, T.-W., Phillips, B.J. and Schmezer, P. (1994) The effect of various antioxidants and other modifiying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay. Mutat. Res., 307, 261-271.
36. Bijur, G.N., Ariza, M.E., Hitchcock, C.L. and Williams, M.V. (1997) Antimutagenic and promutagenic activity of ascorbic acid during oxidative stress. Environ. Mol. Mutagen., 30, 339-345.
37. Tsutsui, T., Hayashi, N., Maizumi, H., Huff, J. and Barrett, J.C. (1997) Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells. Mutat. Res., 373, 113-123.
38. Izzotti, A., Balansky, R., Scatolini, L., Rovida, A. and De Flora, S. (1995) Inhibition by N-acetylcysteine of carcinogen-DNA adducts in the tracheal epithelium of rats exposed to cigarette smoke. Carcinogenesis, 16, 669-672.
39. 2-propanodeoxy-guanosine adducts: potential new biomarkers of smoking-induced DNA damage in human oral tissue. Cancer Res., 58, 581-584.
40. Celotti, L., Furlan, D., Ferraro, P. and Levis, A.G. (1989) DNA repair and replication in lymphocytes from smokers exposed in vitro to UV light. Mutagenesis, 4, 82-86.
41. Sawada, S., Asakura, S., Daimon, H. and Furihata, C. (1995) Comparison of autoradiography, liquid scintillation counting and immunoenzymatic staining of 5-bromo-2′-deoxyuridine for measurement of unscheduled DNA synthesis in rat liver. Mutat. Res., 344, 109-116.
42. Kaina, B. (1998) Critical steps in alkylation-induced aberration formation. Mutat. Res., 404, 119-124.
43. Galloway, S.M., Miller, J.E., Armstrong, M.J., Bean, C.L., Skopek, T.R. and Nichols, W.W. (1998) DNA synthesis inhibition as an indirect mechanism of chromosome aberrations: comparison of DNA-reactive and non-DNA-reactive clastogens. Mutat. Res., 400, 169-186.
44. Chung, F.L., Chen, H.J. and Nath, R.G. (1996) Lipid peroxidation as potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis, 17, 2105-2111.