Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells

International Immunology

Volumn 14, Issue 8, 2002, Pages 883-892

  Corcione, Anna ^a   Tortolina, Giuseppe ^b   Bonecchi, Raffaella ^c   Battilana, Nicoletta ^a   Taborelli, Giuseppe ^a   Malavasi, Fabio ^d   Sozzani, Silvano ^c   Ottonello, Luciano ^b   Dallegri, Franco ^b   Pistoia, Vito ^a  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

B cells subsets; Chemokine receptors; Chemokines; Locomotion

Indexed keywords

CD38 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR6; EOTAXIN; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; BETA CHEMOKINE; CC CHEMOKINE RECEPTOR 1; CC CHEMOKINE RECEPTOR 4; CHEMOKINE RECEPTOR; LIGAND; MESSENGER RNA; MONOCYTE CHEMOATTRACTANT PROTEIN 1 RECEPTOR;

ARTICLE; B LYMPHOCYTE; CELL ISOLATION; CHEMOTAXIS; CONTROLLED STUDY; FLOW CYTOMETRY; GERMINAL CENTER; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE CULTURE; LYMPHOCYTE MIGRATION; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TONSIL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS;

B-LYMPHOCYTE SUBSETS; CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; GENE EXPRESSION; GERMINAL CENTER; HUMANS; IMMUNOLOGIC MEMORY; LIGANDS; RECEPTORS, CHEMOKINE; RNA, MESSENGER; TONSIL;

EID: 0035993992     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxf054     Document Type: Article

References (66)

1. Lymphocyte homing and homeostasis
2. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration
3. Developmental switches in chemokine response profiles during B cell differentiation and maturation
4. The dynamic relationships between B-cell populations in adults
5. The paths and molecular controls of peripheral B cell development
6. Mechanisms of antigen-driven selection in germinal centers
7. Maturation of immune responses in germinal centers
8. Expansion, selection and mutation of antigen-specific B cells in germinal centers
9. Germinal centers
10. Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones
11. Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2
12. Chemokines and leukocyte traffic
13. Chemokines and cell migration in secondary lymphoid organs
14. Chemokines: Signal lamps for trafficking of T and B cells for development and effector function
15. h2-mediate responses
16. Recent advances in chemokines and chemokine receptors
17. Chemokines
18. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement
19. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
20. The chemokine SDF-1α triggers the chemotactic response and induce cell polarization in human B lymphocytes
21. Activation-dependent modulation of B lymphocyte migration to chemokines
22. A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC) is a highly efficient chemoattractant for B cells and activated T cells
23. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells
24. CKβ-11 macrophage inflammatory protein-3β EB1-ligand chemokine is an efficacious chemoattractant for T and B cells
25. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
26. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma
27. Stromal cell-derived factor-1 as a chemoattractant for follicular center lymphoma B cells
28. Defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
29. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
30. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
31. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
32. Expression of the G-protein-coupled receptor BLR-1 defines mature, recirculating B cells and a subset of T-helper memory cells
33. A putative chemokine receptor, BLR-1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
34. Human macrophage inflammatory protein α (MIP-1α) and MIP-1β chemokines attract distinct populations of lymphocytes
35. Chemotaxis and IL-8 receptor expression in B cells from normal and HIV-infected subjects
36. Characterization of the CCR2 chemokine receptor: Functional CCR receptor expression in B cells
37. Regulation of CCR6 chemokine receptor expression and responsiveness to macrophage inflammatory protein-3α/CCL20 in human B cells
38. Characterization of a murine monoclonal antibody specific for human early lympho-hemopoietic cells
39. Spontaneous production of granulocyte-macrophage colony-stimulating factor in vitro by human B-lineage lymphocytes is a distinctive marker of germinal center cells
40. Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor
41. Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
42. The MCP/eotaxin subfamily of CC chemokines
43. - B cell compartment: Identification of two major tonsillar B cell subsets
44. Analysis of somatic mutation in five B cell subsets of human tonsil
45. Microanatomy of lymphoid tissues during humoral immune responses: Structure function relationships
46. Human macrophage inflammatory protein-α (MIP-1α) and MIP-1β chemokines attract distinct population of lymphocytes
47. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3α
48. Characterisation of macrophage inflammatory protein-5/human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines
49. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4
50. The role of chemokines in regulating cell migration during humoral immune responses
51. CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophagetropic HIV-1
52. Molecular cloning and functional expression of a new human CC-chemokine receptor gene
53. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES
54. Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor
55. Molecular cloning, functional expression and signalling characteristics of a CC chemokine receptor
56. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro
57. Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC
58. Recombinant tumor necrosis factor enhances the locomotion of memory and naive B lymphocytes from human tonsils through the selective engagement of the type II receptor
59. rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: Implications for B cell trafficking in secondary lymphoid tissues
60. A tissue-specific endothelial cell molecule involved in lymphocyte homing
61. A cell surface molecule involved in organ-specific homing of lymphocytes
62. Locomotor properties of human germinal centre B cells: Activation by anti-CD40 and IL-4 allows chemoattraction by anti-immunoglobulin
63. Rheumatoid arthritis: Pathophysiology and implications for therapy
64. New developments in Sjögren's syndrome
65. Antigen receptor engagement selectively induces macrophage inflammatory protein-1α (MIP-1α) and MIP-1β chemokine production in human B cells
66. Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells