ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis

Biochemical and Biophysical Research Communications

Volumn 355, Issue 4, 2007, Pages 1038-1044

  Yan, Weihua ^a   Arai, Ayako ^a   Aoki, Mae ^a   Ichijo, Hidenori ^b   Miura, Osamu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Arsenic trioxide; ASK1; JNK; p38

Indexed keywords

ACETYLCYSTEINE; APOPTOSIS SIGNAL REGULATING KINASE 1; ARSENIC TRIOXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; ENZYME ACTIVATION; ENZYME DEFICIENCY; ENZYME REPRESSION; FIBROBLAST; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; ARSENICALS; CELL LINE; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUKEMIA; MAP KINASE KINASE KINASE 5; MICE; OXIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

MURINAE; MUS;

EID: 33847636024     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.02.064     Document Type: Article

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