A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement

Journal of Immunology

Volumn 183, Issue 10, 2009, Pages 6227-6235

  Choi, Chul Won ^a,b   Chung, Yang Jo ^a   Slape, Christopher ^a,c   Aplan, Peter D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Korea University College of Medicine   (South Korea)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOSIALIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADOLESCENT; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CLONAL VARIATION; CONTROLLED STUDY; ERYTHROID CELL; FUSION GENE; GENE; GENE OVEREXPRESSION; GENE REARRANGEMENT; HEMATOPOIESIS; HOXA10 GENE; HOXA7 GENE; HOXA9 GENE; LYMPHATIC LEUKEMIA; LYMPHOBLASTOMA; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTOPENIA; MOUSE; MYELODYSPLASTIC SYNDROME; NONHUMAN; NUP98 HOXD13 GENE; PRE B LYMPHOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; THYMOCYTE; VDJ EXON;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; CELL DIFFERENTIATION; GENE EXPRESSION; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; HOMEODOMAIN PROTEINS; MICE; MYELODYSPLASTIC SYNDROMES; NUCLEAR PORE COMPLEX PROTEINS; ONCOGENE PROTEINS, FUSION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 77950542037     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901121     Document Type: Article

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