메뉴 건너뛰기




Volumn 107, Issue 13, 2010, Pages 5699-5700

Targeting a kinetochore-associated motor protein to kill cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CENTROMERE PROTEIN E; GSK 923295; KINESIN; KINESIN 5; MONASTROL; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 77950539813     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001277107     Document Type: Note
Times cited : (3)

References (18)
  • 1
    • 77950525308 scopus 로고    scopus 로고
    • Antitumor activity of an allosteric inhibitor of centromere-associated protein-E (CENP-E)
    • Wood KW, et al. (2010) Antitumor activity of an allosteric inhibitor of centromere-associated protein-E (CENP-E). Proc Natl Acad Sci USA 107:5839-5844.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5839-5844
    • Wood, K.W.1
  • 2
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA, Wilson L (2004) Microtubules as a target for anticancer drugs. Nat Rev Cancer 4:253-265.
    • (2004) Nat Rev Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 3
    • 7744233719 scopus 로고    scopus 로고
    • Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
    • Rieder CL, Maiato H (2004) Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint. Dev Cell 7:637-651.
    • (2004) Dev Cell , vol.7 , pp. 637-651
    • Rieder, C.L.1    Maiato, H.2
  • 4
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • DOI 10.1126/science.286.5441.971
    • Mayer TU, et al. (1999) Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286:971-974. (Pubitemid 33594038)
    • (1999) Science , vol.286 , Issue.5441 , pp. 971-974
    • Mayer, T.U.1    Kapoor, T.M.2    Haggarty, S.J.3    King, R.W.4    Schreiber, S.L.5    Mitchison, T.J.6
  • 5
    • 24344465919 scopus 로고    scopus 로고
    • Analysis of the kinesin superfamily: Insights into structure and function
    • DOI 10.1016/j.tcb.2005.07.006, PII S0962892405001820
    • Miki H, Okada Y, Hirokawa N (2005) Analysis of the kinesin superfamily: Insights into structure and function. Trends Cell Biol 15:467-476. (Pubitemid 41253466)
    • (2005) Trends in Cell Biology , vol.15 , Issue.9 , pp. 467-476
    • Miki, H.1    Okada, Y.2    Hirokawa, N.3
  • 6
    • 77949540170 scopus 로고    scopus 로고
    • How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays
    • in Press
    • Wordeman L (2010) How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays. Semin Cell Dev Biol, in press.
    • (2010) Semin Cell Dev Biol
    • Wordeman, L.1
  • 7
    • 17144405643 scopus 로고    scopus 로고
    • Mitotic kinesins: Prospects for antimitotic drug discovery
    • DOI 10.2174/1568026053507697
    • Bergnes G, Brejc K, Belmont L (2005) Mitotic kinesins: Prospects for antimitotic drug discovery. Curr Top Med Chem 5:127-145. (Pubitemid 40514510)
    • (2005) Current Topics in Medicinal Chemistry , vol.5 , Issue.2 , pp. 127-145
    • Bergnes, G.1    Brejc, K.2    Belmont, L.3
  • 8
    • 59449092629 scopus 로고    scopus 로고
    • Centromere-associated protein E: A motor that puts the brakes on the mitotic checkpoint
    • Wood KW, Chua P, Sutton D, Jackson JR (2008) Centromere-associated protein E: A motor that puts the brakes on the mitotic checkpoint. Clin Cancer Res 14:7588-7592.
    • (2008) Clin Cancer Res , vol.14 , pp. 7588-7592
    • Wood, K.W.1    Chua, P.2    Sutton, D.3    Jackson, J.R.4
  • 9
    • 0001665802 scopus 로고    scopus 로고
    • CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint
    • Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW (2000) CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol 2:484-491.
    • (2000) Nat Cell Biol , vol.2 , pp. 484-491
    • Yao, X.1    Abrieu, A.2    Zheng, Y.3    Sullivan, K.F.4    Cleveland, D.W.5
  • 10
    • 31144471300 scopus 로고    scopus 로고
    • Chromosomes can congress to the metaphase plate before biorientation
    • Kapoor TM, et al. (2006) Chromosomes can congress to the metaphase plate before biorientation. Science 311:388-391.
    • (2006) Science , vol.311 , pp. 388-391
    • Kapoor, T.M.1
  • 11
  • 12
    • 34247333444 scopus 로고    scopus 로고
    • Thespindle-assembly checkpoint in space and time
    • Musacchio A, Salmon ED (2007)Thespindle-assembly checkpoint in space and time.Nat RevMol Cell Biol 8:379-393.
    • (2007) Nat RevMol Cell Biol , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 13
    • 24944452696 scopus 로고    scopus 로고
    • Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
    • DOI 10.1083/jcb.200505040
    • Mao Y, Desai A, Cleveland DW (2005) Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J Cell Biol 170:873-880. (Pubitemid 41306286)
    • (2005) Journal of Cell Biology , vol.170 , Issue.6 , pp. 873-880
    • Mao, Y.1    Desai, A.2    Cleveland, D.W.3
  • 14
    • 0035945356 scopus 로고    scopus 로고
    • Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
    • Howell BJ, et al. (2001) Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J Cell Biol 155:1159-1172.
    • (2001) J Cell Biol , vol.155 , pp. 1159-1172
    • Howell, B.J.1
  • 16
    • 77950532577 scopus 로고    scopus 로고
    • Discovery of GSK923295, the first potent and selective inhibitor of centromere-associated protein E (CENP-E)
    • in press
    • Qian X, et al. Discovery of GSK923295, the first potent and selective inhibitor of centromere-associated protein E (CENP-E). ACS Med Chem Lett, in press.
    • ACS Med Chem Lett
    • Qian, X.1
  • 17
    • 33846065784 scopus 로고    scopus 로고
    • Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
    • DOI 10.1016/j.ccr.2006.12.003, PII S1535610806003680
    • Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW (2007) Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 11:25-36. (Pubitemid 46070223)
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 25-36
    • Weaver, B.A.A.1    Silk, A.D.2    Montagna, C.3    Verdier-Pinard, P.4    Cleveland, D.W.5
  • 18
    • 33846523617 scopus 로고    scopus 로고
    • Targeted anti-mitotic therapies: Can we improve on tubulin agents?
    • Jackson JR, Patrick DR, Dar MM, Huang PS (2007) Targeted anti-mitotic therapies: Can we improve on tubulin agents? Nat Rev Cancer 7:107-117.
    • (2007) Nat Rev Cancer , vol.7 , pp. 107-117
    • Jackson, J.R.1    Patrick, D.R.2    Dar, M.M.3    Huang, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.