-
1
-
-
0036495230
-
Formation of a nona-oxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement
-
Ben-Shabat S., Itagaki Y., Jockusch S., Sparrow J.R., Turro N.J., Nakanishi K. Formation of a nona-oxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement. Angewandte Chemie International Edition 2002, 41(5):814-817.
-
(2002)
Angewandte Chemie International Edition
, vol.41
, Issue.5
, pp. 814-817
-
-
Ben-Shabat, S.1
Itagaki, Y.2
Jockusch, S.3
Sparrow, J.R.4
Turro, N.J.5
Nakanishi, K.6
-
2
-
-
0036510535
-
Biosynthetic studies of A2E, a major fluorophore of RPE lipofuscin
-
Ben-Shabat S., Parish C.A., Vollmer H.R., Itagaki Y., Fishkin N., Nakanishi K., et al. Biosynthetic studies of A2E, a major fluorophore of RPE lipofuscin. Journal of Biological Chemistry 2002, 277(9):7183-7190.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.9
, pp. 7183-7190
-
-
Ben-Shabat, S.1
Parish, C.A.2
Vollmer, H.R.3
Itagaki, Y.4
Fishkin, N.5
Nakanishi, K.6
-
3
-
-
0028953831
-
In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics
-
Delori F.C., Dorey C.K., Staurenghi G., Arend O., Goger D.G., Weiter J.J. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Investigative Ophthalmology and Visual Science 1995, 36(3):718-729.
-
(1995)
Investigative Ophthalmology and Visual Science
, vol.36
, Issue.3
, pp. 718-729
-
-
Delori, F.C.1
Dorey, C.K.2
Staurenghi, G.3
Arend, O.4
Goger, D.G.5
Weiter, J.J.6
-
5
-
-
77950516401
-
Origin of fundus autofluorescence
-
Springer-Verlag, Berlin, Heidelberg, F.G. Holz, S. Schmitz-Valckenberg, R.F. Spaide, A.C. Bird (Eds.)
-
Delori F.C., Keilhauer C., Sparrow J.R., Staurenghi G. Origin of fundus autofluorescence. Atlas of fundus autofluorescence imaging 2007, 17-29. Springer-Verlag, Berlin, Heidelberg. F.G. Holz, S. Schmitz-Valckenberg, R.F. Spaide, A.C. Bird (Eds.).
-
(2007)
Atlas of fundus autofluorescence imaging
, pp. 17-29
-
-
Delori, F.C.1
Keilhauer, C.2
Sparrow, J.R.3
Staurenghi, G.4
-
6
-
-
0028783668
-
In vivo measurement of lipofuscin in Stargardt's disease - Fundus flavimaculatus
-
Delori F.C., Staurenghi G., Arend O., Dorey C.K., Goger D.G., Weiter J.J. In vivo measurement of lipofuscin in Stargardt's disease - Fundus flavimaculatus. Investigative Ophthalmology and Visual Science 1995, 36(11):2327-2331.
-
(1995)
Investigative Ophthalmology and Visual Science
, vol.36
, Issue.11
, pp. 2327-2331
-
-
Delori, F.C.1
Staurenghi, G.2
Arend, O.3
Dorey, C.K.4
Goger, D.G.5
Weiter, J.J.6
-
7
-
-
0023814969
-
Fluorophores of the human retinal pigment epithelium: Separation and spectral characterization
-
Eldred G.E., Katz M.L. Fluorophores of the human retinal pigment epithelium: Separation and spectral characterization. Experimental Eye Research 1988, 47(1):71-86.
-
(1988)
Experimental Eye Research
, vol.47
, Issue.1
, pp. 71-86
-
-
Eldred, G.E.1
Katz, M.L.2
-
8
-
-
0027410970
-
Retinal age pigments generated by self-assembling lysosomotropic detergents
-
Eldred G.E., Lasky M.R. Retinal age pigments generated by self-assembling lysosomotropic detergents. Nature 1993, 361(6414):724-726.
-
(1993)
Nature
, vol.361
, Issue.6414
, pp. 724-726
-
-
Eldred, G.E.1
Lasky, M.R.2
-
9
-
-
7044247769
-
Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments
-
Fishkin N., Pescitelli G., Sparrow J.R., Nakanishi K., Berova N. Absolute configurational determination of an all-trans-retinal dimer isolated from photoreceptor outer segments. Chirality 2004, 16:637-641.
-
(2004)
Chirality
, vol.16
, pp. 637-641
-
-
Fishkin, N.1
Pescitelli, G.2
Sparrow, J.R.3
Nakanishi, K.4
Berova, N.5
-
10
-
-
18844379122
-
Isolation and characterization of a retinal pigment epithelial cell fluorophore: An all-trans-retinal dimer conjugate
-
Fishkin N., Sparrow J.R., Allikmets R., Nakanishi K. Isolation and characterization of a retinal pigment epithelial cell fluorophore: An all-trans-retinal dimer conjugate. Proceedings of the National Academy of Sciences of the United States of America 2005, 102(20):7091-7096.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.20
, pp. 7091-7096
-
-
Fishkin, N.1
Sparrow, J.R.2
Allikmets, R.3
Nakanishi, K.4
-
11
-
-
0035069027
-
Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration
-
Holz F.G., Bellman C., Staudt S., Schutt F., Volcker H.E. Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Investigative Ophthalmology and Visual Science 2001, 42(5):1051-1056.
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.5
, pp. 1051-1056
-
-
Holz, F.G.1
Bellman, C.2
Staudt, S.3
Schutt, F.4
Volcker, H.E.5
-
12
-
-
0033026846
-
Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration
-
Holz F.G., Bellmann C., Margaritidis M., Schutt F., Otto T.P., Volcker H.E. Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration. Graefe's Archive for Clinical and Experimental Ophthalmology 1999, 237:145-152.
-
(1999)
Graefe's Archive for Clinical and Experimental Ophthalmology
, vol.237
, pp. 145-152
-
-
Holz, F.G.1
Bellmann, C.2
Margaritidis, M.3
Schutt, F.4
Otto, T.P.5
Volcker, H.E.6
-
13
-
-
28844447280
-
Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cells lipofuscin
-
Jang Y.P., Matsuda H., Itagaki Y., Nakanishi K., Sparrow J.R. Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cells lipofuscin. Journal of Biological Chemistry 2005, 280:39732-39739.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 39732-39739
-
-
Jang, Y.P.1
Matsuda, H.2
Itagaki, Y.3
Nakanishi, K.4
Sparrow, J.R.5
-
14
-
-
4143075923
-
The Rpe65 Leu450Met variant is associated with reduced levels of the RPE lipofuscin fluorophores A2E and iso-A2E
-
Kim S.R., Fishkin N., Kong J., Nakanishi K., Allikmets R., Sparrow J.R. The Rpe65 Leu450Met variant is associated with reduced levels of the RPE lipofuscin fluorophores A2E and iso-A2E. Proceedings of the National Academy of Sciences of the United States of America 2004, 101(32):11668-11672.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.32
, pp. 11668-11672
-
-
Kim, S.R.1
Fishkin, N.2
Kong, J.3
Nakanishi, K.4
Allikmets, R.5
Sparrow, J.R.6
-
15
-
-
34548513286
-
Characterization of dihydro-A2PE: An Intermediate in the A2E biosynthetic pathway
-
Kim S.R., He J., Yanase E., Jang Y.P., Berova N., Sparrow J.R., et al. Characterization of dihydro-A2PE: An Intermediate in the A2E biosynthetic pathway. Biochemistry 2007, 46:10122-10129.
-
(2007)
Biochemistry
, vol.46
, pp. 10122-10129
-
-
Kim, S.R.1
He, J.2
Yanase, E.3
Jang, Y.P.4
Berova, N.5
Sparrow, J.R.6
-
16
-
-
37649001974
-
The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model
-
Kim S.R., Jang Y.P., Jockusch S., Fishkin N.E., Turro N.J., Sparrow J.R. The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:19273-19278.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 19273-19278
-
-
Kim, S.R.1
Jang, Y.P.2
Jockusch, S.3
Fishkin, N.E.4
Turro, N.J.5
Sparrow, J.R.6
-
18
-
-
0034703010
-
The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane
-
Liu J., Itagaki Y., Ben-Shabat S., Nakanishi K., Sparrow J.R. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane. Journal of Biological Chemistry 2000, 275(38):29354-29360.
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.38
, pp. 29354-29360
-
-
Liu, J.1
Itagaki, Y.2
Ben-Shabat, S.3
Nakanishi, K.4
Sparrow, J.R.5
-
19
-
-
0035092144
-
Phenotypic subtypes of Stargardt macular dystrophy - fundus flavimaculatus
-
Lois N., Holder G.E., Bunce C.V., Fitzke F.W., Bird A.C. Phenotypic subtypes of Stargardt macular dystrophy - fundus flavimaculatus. Archives of Ophthalmology 2001, 119:359-369.
-
(2001)
Archives of Ophthalmology
, vol.119
, pp. 359-369
-
-
Lois, N.1
Holder, G.E.2
Bunce, C.V.3
Fitzke, F.W.4
Bird, A.C.5
-
20
-
-
0036177784
-
Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss
-
Lois N., Owens S.L., Coco R., Hopkins J., Fitzke F.W., Bird A.C. Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss. American Journal of Ophthalmology 2002, 133:341-349.
-
(2002)
American Journal of Ophthalmology
, vol.133
, pp. 341-349
-
-
Lois, N.1
Owens, S.L.2
Coco, R.3
Hopkins, J.4
Fitzke, F.W.5
Bird, A.C.6
-
21
-
-
0032438193
-
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
-
Parish C.A., Hashimoto M., Nakanishi K., Dillon J., Sparrow J.R. Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America 1998, 95(25):14609-14613.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14609-14613
-
-
Parish, C.A.1
Hashimoto, M.2
Nakanishi, K.3
Dillon, J.4
Sparrow, J.R.5
-
22
-
-
33644795859
-
Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: A potential therapy for treatment of lipofuscin-based retinal diseases
-
Radu R.A., Han Y., Bui T.V., Nusinowitz S., Bok D., Lichter J., et al. Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: A potential therapy for treatment of lipofuscin-based retinal diseases. Investigative Ophthalmology and Visual Science 2005, 46:4393-4401.
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, pp. 4393-4401
-
-
Radu, R.A.1
Han, Y.2
Bui, T.V.3
Nusinowitz, S.4
Bok, D.5
Lichter, J.6
-
23
-
-
0029985705
-
Ocular age pigment " A2E": An unprecedented pyridinium bisretinoid
-
Sakai N., Decatur J., Nakanishi K., Eldred G.E. Ocular age pigment " A2E": An unprecedented pyridinium bisretinoid. Journal of the American Chemical Society 1996, 118:1559-1560.
-
(1996)
Journal of the American Chemical Society
, vol.118
, pp. 1559-1560
-
-
Sakai, N.1
Decatur, J.2
Nakanishi, K.3
Eldred, G.E.4
-
24
-
-
9444239272
-
Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration
-
Schmitz-Valckenberg S., Bultmann S., Dreyhaupt J., Bindewald A., Holz F.G., Rohrschneider K. Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration. Investigative Ophthalmology and Visual Science 2004, 45:4470-4476.
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, pp. 4470-4476
-
-
Schmitz-Valckenberg, S.1
Bultmann, S.2
Dreyhaupt, J.3
Bindewald, A.4
Holz, F.G.5
Rohrschneider, K.6
-
25
-
-
0942287249
-
Photopic and scotopic fine matrix mapping of retinal areas of increased fundus autofluorescence in patients with age-related maculopathy
-
Scholl H.P.N., Bellmann C., Dandekar S.S., Bird A.C., Fitzke F.W. Photopic and scotopic fine matrix mapping of retinal areas of increased fundus autofluorescence in patients with age-related maculopathy. Investigative Ophthalmology and Visual Science 2004, 45:574-583.
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, pp. 574-583
-
-
Scholl, H.P.N.1
Bellmann, C.2
Dandekar, S.S.3
Bird, A.C.4
Fitzke, F.W.5
-
26
-
-
84895324558
-
Lipofuscin of the retinal pigment epithelium
-
Springer, Heidelberg, F.G. Holz, S. Schmitz-Valckenberg, R.F. Spaide, A.C. Bird (Eds.)
-
Sparrow J.R. Lipofuscin of the retinal pigment epithelium. Atlas of autofluorescence imaging 2007, 3-16. Springer, Heidelberg. F.G. Holz, S. Schmitz-Valckenberg, R.F. Spaide, A.C. Bird (Eds.).
-
(2007)
Atlas of autofluorescence imaging
, pp. 3-16
-
-
Sparrow, J.R.1
-
27
-
-
0034086115
-
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
-
Sparrow J.R., Nakanishi K., Parish C.A. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Investigative Ophthalmology and Visual Science 2000, 41(7):1981-1989.
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.7
, pp. 1981-1989
-
-
Sparrow, J.R.1
Nakanishi, K.2
Parish, C.A.3
-
28
-
-
0032710514
-
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
-
Sparrow J.R., Parish C.A., Hashimoto M., Nakanishi K. A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. Investigative Ophthalmology and Visual Science 1999, 40(12):2988-2995.
-
(1999)
Investigative Ophthalmology and Visual Science
, vol.40
, Issue.12
, pp. 2988-2995
-
-
Sparrow, J.R.1
Parish, C.A.2
Hashimoto, M.3
Nakanishi, K.4
-
29
-
-
0037705336
-
A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation
-
Sparrow J.R., Vollmer-Snarr H.R., Zhou J., Jang Y.P., Jockusch S., Itagaki Y., et al. A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. Journal of Biological Chemistry 2003, 278:18207-18213.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 18207-18213
-
-
Sparrow, J.R.1
Vollmer-Snarr, H.R.2
Zhou, J.3
Jang, Y.P.4
Jockusch, S.5
Itagaki, Y.6
-
30
-
-
0036205219
-
Involvement of oxidative mechanisms in blue light induced damage to A2E-laden RPE
-
Sparrow J.R., Zhou J., Ben-Shabat S., Vollmer H., Itagaki Y., Nakanishi K. Involvement of oxidative mechanisms in blue light induced damage to A2E-laden RPE. Investigative Ophthalmology and Visual Science 2002, 43(4):1222-1227.
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.4
, pp. 1222-1227
-
-
Sparrow, J.R.1
Zhou, J.2
Ben-Shabat, S.3
Vollmer, H.4
Itagaki, Y.5
Nakanishi, K.6
-
31
-
-
0037408428
-
DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue light illumination
-
Sparrow J.R., Zhou J., Cai B. DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue light illumination. Investigative Ophthalmology and Visual Science 2003, 44:2245-2251.
-
(2003)
Investigative Ophthalmology and Visual Science
, vol.44
, pp. 2245-2251
-
-
Sparrow, J.R.1
Zhou, J.2
Cai, B.3
-
32
-
-
0001240249
-
Mechanism of thermolysis of endoperoxides of aromatic compounds. Activation parameters, magnetic field, and magnetic isotope effects
-
Turro N.J., Chow M.-F., Rigaudyo J. Mechanism of thermolysis of endoperoxides of aromatic compounds. Activation parameters, magnetic field, and magnetic isotope effects. Journal of the American Chemical Society 1981, 103:7218-7222.
-
(1981)
Journal of the American Chemical Society
, vol.103
, pp. 7218-7222
-
-
Turro, N.J.1
Chow, M.-F.2
Rigaudyo, J.3
-
34
-
-
0344830731
-
Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope
-
von Rückmann A., Fitzke F.W., Bird A.C. Fundus autofluorescence in age-related macular disease imaged with a laser scanning ophthalmoscope. Investigative Ophthalmology and Visual Science 1997, 38(2):478-486.
-
(1997)
Investigative Ophthalmology and Visual Science
, vol.38
, Issue.2
, pp. 478-486
-
-
von Rückmann, A.1
Fitzke, F.W.2
Bird, A.C.3
-
35
-
-
67749135744
-
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease
-
Wu Y., Fishkin N.E., Pande A., Pande J., Sparrow J.R. Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease. Journal of Biological Chemistry 2009, 284:20155-20166.
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 20155-20166
-
-
Wu, Y.1
Fishkin, N.E.2
Pande, A.3
Pande, J.4
Sparrow, J.R.5
-
36
-
-
15244351557
-
Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells
-
Zhou J., Cai B., Jang Y.P., Pachydaki S., Schmidt A.M., Sparrow J.R. Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells. Experimental Eye Research 2005, 80:567-580.
-
(2005)
Experimental Eye Research
, vol.80
, pp. 567-580
-
-
Zhou, J.1
Cai, B.2
Jang, Y.P.3
Pachydaki, S.4
Schmidt, A.M.5
Sparrow, J.R.6
-
37
-
-
33750814597
-
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
-
Zhou J., Jang Y.P., Kim S.R., Sparrow J.R. Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:16182-16187.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 16182-16187
-
-
Zhou, J.1
Jang, Y.P.2
Kim, S.R.3
Sparrow, J.R.4
-
38
-
-
62649135260
-
Complement activation by bisretinoid constituents of RPE lipofuscin
-
Zhou J., Kim S.R., Westlund B.S., Sparrow J.R. Complement activation by bisretinoid constituents of RPE lipofuscin. Investigative Ophthalmology and Visual Science 2009, 50:1392-1399.
-
(2009)
Investigative Ophthalmology and Visual Science
, vol.50
, pp. 1392-1399
-
-
Zhou, J.1
Kim, S.R.2
Westlund, B.S.3
Sparrow, J.R.4
|