The presence of JC virus in gastric carcinomas correlates with patient's age, intestinal histological type and aberrant methylation of tumor suppressor genes

Modern Pathology

Volumn 23, Issue 4, 2010, Pages 522-530

  Ksiaa, Feryel ^a   Ziadi, Sonia ^a   Mokni, Moncef ^a   Korbi, Sadok ^a   Trimeche, Mounir ^a  

^a FARHAT HACHED HOSPITAL   (Tunisia)

Author keywords

Gastric cancer; Methylation; Polyomaviruses; Tumor suppressor genes

Indexed keywords

PROTEIN P53; VIRUS T ANTIGEN;

ADULT; AGE; AGED; ARTICLE; BK VIRUS; CANCER SURVIVAL; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; JC VIRUS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIMIAN VIRUS 40; STOMACH CARCINOMA; STOMACH MUCOSA; TUMOR SUPPRESSOR GENE; VIRUS DETECTION; VIRUS INFECTION;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIGENS, VIRAL, TUMOR; DNA METHYLATION; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; JC VIRUS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYOMAVIRUS INFECTIONS; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS; TUMOR VIRUS INFECTIONS;

EID: 77950519126     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2009.184     Document Type: Article

References (43)

1. Parkin DM, Bray F, Ferlay J, et al. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001; 94:153-156. (Pubitemid 32911406)
2. Jemal A, Tiwari RC, Murray T, et al. Cancer statistics, 2004. CA Cancer J Clinicians 2004;54:8-29.
3. Starzynska T. Molecular epidemiology of gastric cancer. Dig Dis 2007;25:222-224. (Pubitemid 350194172)
4. Lochhead P, El-Omar EM. Gastric cancer. Br Med Bull 2008;85:87-100. (Pubitemid 351398296)
5. Tamura G. Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. W J Gastroenterol 2006;12:192-198. (Pubitemid 43336916)
6. Kim TY, Jong HS, Jung Y, et al. DNA hypermethylation in gastric cancer. Alim Pharmacol Therap 2004;20: 131-142. (Pubitemid 39120285)
7. Oue N, Oshimo Y, Nakayama H, et al. DNA methyla-tion of multiple genes in gastric carcinoma: association with histological type and CpG island methylator phenotype. Cancer Sci 2003;94:901-905. (Pubitemid 37406973)
8. Verma M. Viral genes and methylation. Ann NY Acad Sci 2003;983:170-180. (Pubitemid 36399330)
9. Elgui de Oliveira D. DNA viruses in human cancer: an integrated overview on fundamental mechanisms of viral carcinogenesis. Cancer Lett 2007;247:182-196.
10. Nardone G, Compare D, De Colibus P, et al. Helico-bacter pylori and epigenetic mechanisms underlying gastric carcinogenesis. Dig Dis 2007;25:225-229. (Pubitemid 350194173)
11. Kang GH, Lee S, Kim WH, et al. Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol 2002;160:787-794. (Pubitemid 34224568)
12. Del Valle L, Gordon J, Assimakopoulou M, et al. Detection of JC virus DNA sequences and expression of the viral regulatory protein T-antigen in tumors of the central nervous system. Cancer Res 2001;61: 4287-4293. (Pubitemid 32721002)
13. Boland CR. Evidence for an association between JC Virus and colorectal neoplasia. Cancer Epidemiol Biomarkers Prev 2004;13:2285-2286.
14. Casini B, Borgese L, Del Nonno F, et al. Presence and incidence of DNA sequences of human polyoma-viruses BKV and JCV in colorectal tumor tissues. Anticancer Res 2005;25:1079-1085. (Pubitemid 40546884)
15. Shin SK, Li MS, Fuerst F, et al. Oncogenic T-antigen of JC virus is present frequently in human gastric cancers. Cancer 2006;107:481-488. (Pubitemid 44107207)
16. Murai Y, Zheng HC, Abdel Aziz HO, et al. High JC virus load in gastric cancer and adjacent non-cancerous mucosa. Cancer Sci 2007;98:25-31. (Pubitemid 44803916)
17. Pass HI, Kennedy RC, Carbone M. Evidence for and implications of SV40-like sequences in human me-sotheliomas. Important Adv Oncol 1996;89-108.
18. Rizzo P, Bocchetta M, Powers A, et al. SV40 and the pathogenesis of mesothelioma. Semin Cancer Biol 2001;11:63-71. (Pubitemid 32222752)
19. Vilchez RA, Kozinetz CA, Arrington AS, et al. Simian virus 40 in human cancers. Am J Med 2003; 114:675-684.
20. Butel JS. Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease. Carcino-genesis 2000;21:405-426.
21. White MK, Khalili K. Expression of JC virus regulatory proteins in human cancer: potential mechanisms for tumourigenesis. Eur J Cancer 2005;41:2537-2548. (Pubitemid 41540629)
22. Goel A, Li MS, Nagasaka T, et al. Association of JC virus T-antigen expression with the methylator phe-notype in sporadic colorectal cancers. Gastroenterol-ogy 2006;130:1950-1961. (Pubitemid 43816967)
23. Nosho K, Shima K, Kure S, et al. JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype. Neoplasia 2009;11: 87-95.
24. Sobin LH, Fleming ID. TNM classification of malignant tumors, fifth edition (1997). Union Internationale Contre le Cancer and the American Joint Committee on Cancer. Cancer 1997;80:1803-1804.
25. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An Attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965;64:31-49.
26. Man YG, Moinfar F, Bratthauer GL, et al. An improved method for DNA extraction from paraffin sections. Pathol Res Pract 2001;197:635-642. (Pubitemid 32834404)
27. Saiki RK, Scharf S, Faloona F, et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 1985;20:1350-1354. (Pubitemid 16105164)
28. Arthur RR, Dagostin S, Shah KV. Detection of BK virus and JC virus in urine and brain tissue by the polymerase chain reaction. J Clin Microbiol 1989;27: 1174-1179. (Pubitemid 19136399)
29. Nakatsuka S, Liu A, Dong Z, et al. Simian virus 40 sequences in malignant lymphomas in Japan. Cancer Res 2003;63:7606-7608. (Pubitemid 37466681)
30. Smith RD, Galla JH, Skahan K, et al. Tubulointerstitial nephritis due to a mutant polyomavirus BK virus strain, BKV(Cin), causing end-stage renal disease. J Clin Microbiol 1998;36:1660-1665. (Pubitemid 28226049)
31. Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93:9821-9826. (Pubitemid 26296693)
32. Ksiaa F, Ziadi S, Amara K, et al. Biological significance of promoter hypermethylation of tumor-related genes in patients with gastric carcinomas. Clin Chim Acta 2009;404:128-133.
33. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006;118:3030-3044.
34. Damania B. DNA tumor viruses and human cancer. Trends Microbiol 2007;15:38-44. (Pubitemid 46038728)
35. Ricciardiello L, Laghi L, Ramamirtham P, et al. JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract. Gastroenterol-ogy 2000;119:1228-1235.
36. Boland CR, Luciani MG, Gasche C, et al. Infection, inflammation, and gastrointestinal cancer. Gut 2005;54:1321-1331. (Pubitemid 41192496)
37. Herrera-Goepfert R, Akiba S, Koriyama C, et al. Epstein-Barr virus-associated gastric carcinoma: evidence of age-dependant among a Mexican population. W J Gastroenterol 2005;11:6096-6103. (Pubitemid 43085048)
38. Chang MS, Uozaki H, Chong JM, et al. CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. Clin Cancer Res 2006;12:2995-3002. (Pubitemid 43837343)
39. Chong JM, Sakuma K, Sudo M, et al. Global and non-random CpG-island methylation in gastric carcinoma associated with Epstein-Barr virus. Cancer Sci 2003; 94:76-80. (Pubitemid 36575862)
40. Goel A, Ricciardiello L, Boland CR. DNA tumor viruses and colorectal cancer. Curr Colorectal Cancer Rep 2007;3:76-81.
41. Amara K, Trimeche M, Ziadi S, et al. Presence of simian virus 40 DNA sequences in diffuse large B-cell lymphomas in Tunisia correlates with aberrant promoter hypermethylation of multiple tumor suppressor genes. Int J Cancer 2007;121:2693-2702. (Pubitemid 350136414)
42. Osawa T, Chong JM, Sudo M, et al. Reduced expression and promoter methylation of p16 gene in Epstein-Barr virus-associated gastric carcinoma. Jpn J Cancer Res 2002;93:1195-1200. (Pubitemid 36032981)
43. Sakuma K, Chong JM, Sudo M, et al. High-density methylation of p14ARF and p16INK4A in Epstein-Barr virus-associated gastric carcinoma. Int J Cancer 2004; 112:273-278. (Pubitemid 39244367)