Genome mining in Amycolatopsis balhimycina for ferredoxins capable of supporting cytochrome P450 enzymes involved in glycopeptide antibiotic biosynthesis

FEMS Microbiology Letters

Volumn 306, Issue 1, 2010, Pages 45-53

  Geib, Nina ^a   Weber, Tilmann ^b   Wörtz, Tanja ^a   Zerbe, Katja ^a   Wohlleben, Wolfgang ^b   Robinson, John A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Balhimycin; Cytochrome P450; Enzyme; Metalloenzymes; Peptide; Vancomycin

Indexed keywords

BALHIMYCIN; CARBON MONOXIDE; CYTOCHROME P450; FERREDOXIN; NONHEME IRON PROTEIN; OXYGENASE; OXYGENASE B; POLYPEPTIDE ANTIBIOTIC AGENT; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VANCOMYCIN;

AMYCOLATOPSIS BALHIMYCINA; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; COMPUTER MODEL; CONTROLLED STUDY; DRUG STRUCTURE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENOME ANALYSIS; IN VITRO STUDY; NOCARDIA ORIENTALIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PSEUDONOCARDIACEAE; SEQUENCE ANALYSIS; SPECIES COMPARISON;

ACTINOMYCETALES; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; CYTOCHROME P-450 ENZYME SYSTEM; DNA, BACTERIAL; ESCHERICHIA COLI; FERREDOXINS; GENOME, BACTERIAL; GLYCOPEPTIDES; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; VANCOMYCIN;

AMYCOLATOPSIS BALHIMYCINA; AMYCOLATOPSIS ORIENTALIS; ESCHERICHIA COLI;

EID: 77950512582     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2010.01933.x     Document Type: Article

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