Mutagenic response of 2.45GHz radiation exposure on rat brain

International Journal of Radiation Biology

Volumn 86, Issue 4, 2010, Pages 334-343

  Kesari, Kavindra Kumar ^a   Behari, J ^a   Kumar, Sanjay ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; Comet assay; DNA strand breaks; Histone kinase; Microwave radiation

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; PROTAMINE KINASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN TISSUE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; MALE; MICROWAVE RADIATION; NONHUMAN; PRIORITY JOURNAL; RADIATION ABSORPTION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; RAT; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BRAIN; CATALASE; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; GLUTATHIONE PEROXIDASE; MALE; MICROWAVES; PROTAMINE KINASE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 77950476008     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553000903564059     Document Type: Article

References (55)

1. Agarwal A, Saleh R. 2002. Role of oxidants in male infertility: Rationale, significance, and treatment. Urologic Clinics of North America 29:817-827. (Pubitemid 36015326)
2. Aitken RJ, Bennetts LE, Sawyer D. 2005. Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline. International Journal of Andrology 28:171-179. (Pubitemid 40780344)
3. Aitken RJ, Harkiss D, Buckingham D. 1993. Relationship between iron catalyzed lipid-peroxidation potential and human sperm function. Journal of Reproduction and Fertility 98:257-265. (Pubitemid 23204773)
4. Albers DS, Beal MF. 2000. Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease. Journal of Neural Transmission (Suppl. 59):133-154. (Pubitemid 30479414)
5. Alvarez JG, Touchstone CJ, Blasco L, Storey BT. 1987. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. SOD as major enzyme protectant against oxygen toxicity. Journal of Andrology 8:33-89.
6. Behari J, Kunjilwar KK, Pyne S. 1998. Interaction of low level modulated RF radiation with Na+- K+ - ATPase. Bioelectrochemistry and Bioenergetics 47:247-252.
7. Behari J, Paulraj R. 2007. Biomarkers of induced electromagnetic field and cancer. Indian Journal of Experimental Biology 45:77-85.
8. Bohr H, Bohr J. 2000. Microwave enhanced kinetics observed in ORD studies of protein. Bioelectromagnetics 21:68-72.
9. Cleary SF. 1990. Biological effects of radiofrequency electromagnetic fields. In: Gandhi OP, editor. Biological effects and medical applications of electromagnetic energy. Englewood Cliffs, NJ: Prentice Hall. pp 236-255.
10. Condell RA, Tappel AL. 1993. Evidence for suitability of glutathione peroxidase as a protective enzyme: Studies of oxidative damage, restoration and proteolysis. Archive Biochemistry Biophysics 223:407.
11. Diem E, Schwarz C, Adlkofer F, Jahn O, Rudiger H. 2005. Nonthermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro. Mutation Research 583(2):178-183. (Pubitemid 40775914)
12. Doree M. 1990. Control of M-phase by maturation-promoting factor. Current Opinion Cell Biology 2:269-273. (Pubitemid 20168615)
13. Dunphy WG, Brizuela L, Beach D, Newport J. 1988. The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. Cell 54:423-431.
14. Durney CH, Iskander MF, Massoudi H, Johnson CC. 1984. An empirical formula for broad band SAR calculations of prolate spheroidal models of humans and animal. In: Osepchuk JM, editor. Biological Effects of Electromagnetic Radiation. New York: IEEE Press. pp 85-90.
15. Foray N, Badie C, Alsbeih G, Fertil B, Malaise EP. 1996. A new model describing the curves for repair of both DNA double strand breaks and chromosome damage. Radiation Research 146:53-60. (Pubitemid 26230833)
16. Gautier J, Norbury C, Lohka M, Nuese P, Mailer J. 1988. Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2. Cell 54:433-439.
17. Grundler W, Kaiser F, Keilmann F, Walleczek, J. 1992. Mechanisms of electromagnetic interaction with cellular systems. Naturwissenschaften 79:551-559.
18. Gurney JG, Van Wijngaarden E. 1999. Extremely low frequency electromagnetic fields (EMF) and brain cancer in adults and children: Review and comment. Neuro-Oncology 212-220.
19. Hanks SK, Quinn AM, Hunter T. 1988. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains. Science 241:42-52.
20. Hanks SK, Hunter T. 1995. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification. Federation of American Societies for Experimental Biology Journal 9:576-596.
21. Hardell L, Carlberg M, Hansson Mild K. 2005. Use of cellular or cordless telephones and the risk for Non-Hodgkin's Lymphoma. International Archives of Occupational and Environmental Health 78(8):625-632. (Pubitemid 41644381)
22. Hunter T, Plowman GD. 1997. The protein kinases of budding yeast: Six score and more. Trends in Biochemical Science 22:18-22. (Pubitemid 27056092)
23. Ilhan A, Gurel A, Armutcu F, Kamisli S, Iraz M, Akyol O, Ozen S. 2004. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clinica Chimica Acta 340:153-162. (Pubitemid 38167519)
24. Iliakis G. 1991. The role of DNA double strand breaks in ionizing radiation induced killing of eukaryotic cells. BioEssays 13:641-648. (Pubitemid 21892586)
25. Jones DP, Eklow L, Thor H, Orrenius S. 1981. Metabolism of hydrogen peroxide in isolated hepatocytes: Relative contributions of catalase and glutathione peroxidase in decomposition of endogenously generated H2O2. Archive of Biochemistry Biophysics 210:505-516. (Pubitemid 12243701)
26. Jung T, Moor RM, Fulka J. 1993. Kinetics of MPF and histone H1 kinase activity differ during the G2- to M-phase transition in mouse oocytes. International Journal of Developmental Biology 37:595-600. (Pubitemid 24063762)
27. Kesari KK, Behari J. 2009a. Fifty-gigahertz microwave exposure effect of radiations on rat brain. Applied Biochemistry and Biotechnology 158(1):126-139.
28. Kesari KK, Behari J. 2009b. Effect of microwave at 2.45 GHz radiations on reproductive system of male rats. Toxicological and Environmental Chemistry 2009. (in press, DOI: 10.1080/ 02772240903233637).
29. Kunjilwar KK, Behari J. 1993. Effect of amplitude modulated radiofrequency radiation on cholenergic system of developing rats. Brain Research 601:321. (Pubitemid 23047700)
30. Labbe JC, Capony JP, Caput D, Cavadore JC, Derancourt J, Kaghad M, Lelias JM, Picard A, Doree M. 1989. MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B. EMBO Journal 8:3053-3058. (Pubitemid 19275008)
31. Lai H. 1998. Neurological effects of radiofrequency electromagnetic radiation. Paper presented at the Workshop on Possible Biological and Health Effects of RF Electromagnetic Fields, Mobile Phone and Health Symposium, 25-28 October 1998; University of Vienna, Vienna, Austria. Available from the website: www.mapcruzin.com
32. Lai H, Singh NP. 1997a. Acute exposure to a 60-Hz magnetic field increases DNA strand breaks in rat brain cells. Bioelectromagnetics 18:156-165. (Pubitemid 127472950)
33. Lai H, Singh NP. 1997b. Melatonin and N-tert-butyl-a-phenylnitrone blocked 60-Hz magnetic field-induced DNA single and double strand breaks in rat brain cells. Journal of Pineal Research 22:152-162. (Pubitemid 127731752)
34. Lai H, Singh NP. 1997c. Melatonin and a spin-trap compound blocked radiofrequency radiation-induced DNA strand breaks in rat brain cells. Bioelectromagnetics 18:446-454. (Pubitemid 127475187)
35. Lai H, Singh NP. 1995. Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. Bioelectromagnetics 16:207-210. (Pubitemid 127472950)
36. Lai H, Singh NP. 1996. Double strand breaks in rats' brain cells after acute exposure to radio frequency electromagnetic radiation. International Journal of Radiation Biology 69:513-521. (Pubitemid 26156821)
37. Lai H, Singh NP. 2004. Magnetic field-induced DNA strand breaks in brain cells of rat. Environmental Health Perspectives 112(6):87-694. (Pubitemid 38628398)
38. Lowry OH, Resebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with folin-phenol reagent. Journal of Biochemistry 193:265-275.
39. Maller JL. 1990. Xenopus oocytes and the biochemistry of cell division. Biochemistry 29:3157-3166.
40. Manning G, Whyte DB, Martinez R, Hunter T, Sundersanam S. 2002. The protein kinase complement of the human genome. Science 298:1912-1934. (Pubitemid 35425239)
41. Meikrantz W, Schlegel RA. 1992. M-phase-promoting factor activation. Journal Cell Science 101:475-481.
42. Moustafa YM,Moustafa RM, Belacy AS, Abou-El-Ela H, Ali FM. 2001. Effects of acute exposure to the radiofrequency fields of cellular phones on plasma lipid peroxide and antioxidase activities in human erythrocytes. Journal of Pharmaceutical and Biomedical Analysis 26:605-608.
43. Neubauer C, Phelan AM, Kues H, Lange DG. 1990. Microwave irradiation of rats at 2.45 GHz activates pinocytotic-like uptake of tracer by capillary endothelial cells of cerebral cortex. Bioelectromagnetics 11(4):261-268.
44. Nikolova T, Czyz J, Rolletschek A, Blyszczuk P, Fuchs J, Jovtchev G, Schuderer J, Kuster N, Wobus AM. 2005. Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neural progenitor cells. Federation of American Societies for Experimental Biology Journal 19(12):1686-1688.
45. Nurse P. 1990. Universal control mechanism regulating onset of M-phase. Nature 344:503-508. (Pubitemid 20124423)
46. Oktem F, Ozguner F, Mollaogu H, Koyu A, Uz E. 2005. Oxidative damage in the kidney induced by 900-MHz-emitted mobile phone: Protection by melatonin. Archives of Medical Research 36:350-355. (Pubitemid 40798387)
47. Paulraj R, Behari J. 2002. The effect of low level continuous 2.45 GHz wave on brain enzymes of developing rat brain. Electromagnetic Biology and Medicine 21(3):231-241. (Pubitemid 36010976)
48. Paulraj R, Behari J. 2006. Single strand DNA breaks in rat brain cells exposed to microwave radiation. Mutation Research 596:76-80.
49. Pawse AR, Margery GO, Stocken LA. 1971. Histone kinase and cell division. Biochemistry Journal 122:713-719.
50. Phillips JL, Ivaschuk O, Ishida-Jones T, Jones RA, Campbell-Beachler M, Haggren W. 1998. DNA damage in MOLT-4 lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro. Bioelectrochemistry and Bioenergetics 45:103-110. (Pubitemid 28264411)
51. Reiter RJ. 1997. Melatonin aspects of exposure to low frequency electric and magnetic fields. In: Advances in electromagnetic fields in living systems. New York: Plenum Press 2:1-27.
52. Salford LG, Brun AE, Eberhardt JL, Malmgren L, Persson BRR. 2003. Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. Environmental Health Perspectives 7:881-883. (Pubitemid 36790379)
53. Singh NP. 2003. DNA double strand breaks using neutral microgel elecrrophoresis. Fertility and Sterility 80:1420-1430.
54. Suzuki YJ, Forman HJ, Sevanian A. 1997. Oxidants as stimulators of signal transduction. Free Radical Biology and Medicine 22:269-285. (Pubitemid 26399334)
55. Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. 2000. Single cell gel/comet assay; guidelines for in vitro and in vivo genetic toxicology testing. Environmental and Molecular Mutagenesis 35:206-221. (Pubitemid 30196665)