Single- and double-strand DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation

International Journal of Radiation Biology

Volumn 69, Issue 4, 1996, Pages 513-521

  Lai, H ^a   Singh, N P ^a  

^a University of Washington   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DNA STRAND BREAKAGE; PRIORITY JOURNAL; RADIOFREQUENCY RADIATION; RAT;

ANIMALS; BRAIN; DNA; DNA DAMAGE; DNA REPAIR; MALE; RADIO WAVES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0029931526     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096145814     Document Type: Article

References (50)

1. AMES, B. K., SHIGENAGA, M. K. and HAGEN, T. M., 1993, Oxidants, antioxidants, and the degenerative diseases of aging. Proceedings of the National Academy of Sciences, USA, 90, 7915-7922.
2. BELYAEV, I. YA., ALIPOV., Y. D., SHCHCEGLOV, V. S. and LYSTSOV, V. N., 1992, Resonance effect of microwaves on the genome conformational state of E. coli cells. Zeitschrift für Naturforschung. Section C. Journal of Biosciences, 47, 621-627.
3. BERNSTEIN, C. and BERNSTEIN, H., 1991, Aging, Sex, and DNA repair (New York: Academic).
4. BLOCHER, D. and POHLIT, W., 1982, DNA double-strand breaks in Ehrlich ascites tumour cells at low doses of X-ray. II. Can cell death be attributed to double strand breaks? International Journal of Radiation Biology, 42, 329-338.
5. BRIDGES, B. A., 1981, Some DNA-repair-deficient human syndromes and their implications for human health. Proceedings of the Royal Society (London), 212, 263-278.
6. CERUTTI, P. A., 1985, Peroxidant states and tumor promotion. Science, 227, 375-381.
7. CHETSANGA, C. J., TUTTLE, M., JACOBONI, A. and JOHNSON, C., 1977, Age-associated structural alterations in senescent mouse brain DNA. Biochimica et Biophysica Acta, 474, 180-187.
8. CHOU, C. K., GUY, A. W. and JOHNSON, R. B., 1984, SAR in rats exposed in 2450-MHz circularly polarized waveguide. Bioelectromagnetics, 5, 389-398.
9. CHOU, C. K., GUY, A. W., MCDOUGALL, J. A. and LAI, H., 1985, Specific absorbtion rate in rats exposed to 2450-MHz microwaves under seven exposure conditions. Bioelectromagnetics, 6, 73-88.
10. CIARAVINO, V., MELZ, M. L. and ERWIN, D. N., 1991, Absence of a synergistic effect between moderate-power radiofrequency electromagnetic radiation and adriamycin on cell cycle progression and sister chromatid exchange. Bioelectromagnetics, 12, 289-298.
11. DIMBYLOW, P. J. and MANN, S. M., 1994, SAR calculation in an anatomically realistic model of the head for mobile communication transceivers at 900 MHz and 1.8 GHz. Physics and Medicine in Biology, 39, 1537-1553.
12. FAIRBAIRN, D. W., OLIVE, P. L. AND O'NEILL, K. L., 1995, The comet assay: a comprehensive review. Mutation Research, 339, 37-59.
13. FAN, S., VIJAYALAXMI, MINDEK, G. and BURKART, W., 1990, Adaptive response to 2 low doses of X-rays in human blood lymphocytes. Mutation Research, 243, 53-56.
14. FRANKENBERG, D., FRENKENBERG-SCHWAGER, M., BLOCHER, D. and HARBICH, R., 1981, Evidence for DNA double-strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiation under oxic or anoxic conditions. Radiation Research, 88, 524-532.
15. GARAJ-VRHOVAC, V., HORVAT, D. and KOREN, Z., 1990, The effect of microwave radiation on cell genome. Mutation Research, 243, 87-93.
16. GARAJ-VRHOVAC, V., HORVAT, D. and KOREN, Z., 1991, The relationship between colony-forming ability, chromosome aberrations and incidence of micronuclei in V79 Chinese hamster cells exposed to microwave radiation. Mutation Research, 263, 143-149.
17. GLANTZ, S. A. and PARMLEY, W. W., 1995, Passive smoking and heart disease: mechanisms and risk. Journal of the American Association, 270, 1047-1053.
18. GOLDBERG, V. P., PARKER, M. I. and GEVERS, W., 1991, The genetic basis of Cancer. South African Medical Journal, 80, 99-104.
19. GUY, A. W., WALLACE, J. and MCDOUGALL, J. A., 1979, Circular polarized 2450-MHz waveguide system for chronic exposure of small animals to microwaves. Radio Science, 14(6s), 63-74.
20. HART, R. W. and SETLOW, R. B., 1974, Correlation between deoxyribonucleic acid excision repair and life span in a number of mammalian species. Proceedings of the National Academy of Sciences, USA, 71, 2169-2173.
21. IEEE Standard for Safety Level with Respect to Human Exposure to Radiofrequency Electromagnetic Fields, 3 KHz-300 GHz, 1992 (IEEE C95.1-1991)-IEEE Standard Coordinating Committee 28 (New York: IEEE).
22. JONES, S. K., NEE, L. E., SWEET, L., POLINSKI, R. I., BARTLETT, J. D., BRADLEY, W. G. and ROBISON, S.H., 1989, Decreased DNA repair in familial Alzheimer's disease. Mutation Research, 219, 247-255.
23. KING, J. S., VALCARCEL, E. R., RUFFER, J. T., PHILLIPS, J. W. and MORAN, W. F., 1993, noncomplementary DNA double strand break rejoining in bacterial and human cells. Nucleic Acids Research, 21, 1055-1059.
24. KIRSCHVINK, J. L., 1994, Ferromagnetic resonance in biogenic magnetite: a plausible mechanism for sub-thermal effects of ELF-modulated microwave radiation. In: Project Abstracts of the Annual Review of Research on Biological Effects of Electric and Magnetic Fields for the Generation, Delivery, and Use of Electricity (Federick MD: W/L Associates), p. 137.
25. KIRSCHVINK, J. L., KIRSCHVINK, A. K. and WOODFORD, B., 1990, Human brain magnetite and squid magnetometry. Annals of IEEE Engineering and Medicine in Biology Society, 12(3), 1089-1090.
26. KODYM, R. and HOERTH, E., 1993, Determination of the radiation sensitivity of the stromal Cells in the murine long-term bone marrow culture by measuring the induction and rejoining of interphase chromosome breaks. International Journal of Radiation Oncology, Biology, Physics, 25, 829-833.
27. LAI, H., 1994, Neurological effects of microwave irradiation. In: Advances in Electromagnetic Fields in Living Systems, vol. 1. Edited by: J. C. Lin (New York: Plenum), pp. 27-80.
28. LAI, H., HORITA, A., CHOU, C. K. and GUY, A. W., 1984, Acute low-level microwave irradiation and the actions of pentobarbital: effects of exposure orientation. Bioelectromagnetics, 5, 203-212.
29. LAI, H. and SINGH, N. P., 1995, Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells. Bioelectromagnetics, 16, 207-210.
30. MAES, A., VERSCHAEVE, L., ARROYO, A., DEWAGTER, C. and VERCRUYSSEN, L., 1993, In vitro cytogenetic effects of 2450 MHz waves on human peripheral blood lymphocytes. Bioelectromagnetics, 14, 495-501.
31. MCKELVEY-MARTIN, V. J., GREEN, M. H., SCHMEZER, P., POOL-ZOBEL, B. L., DE-M'EO, M. P. and COLLINS, A., 1993, The single cell gel electrophoresis assay (comet assay): a European review. Mutation Research, 288, 47-63.
32. MELTZ, M. L., EAGAN, P. and ERWIN, D. N., 1990, Proflavin and microwave radiation: absence of a mutagenic interaction. Bioelectromagnetics, 11, 149-157.
33. MULLAART, E., BOERRIGTER, M. E., BOER, G. J and VIJG, J., 1990a, Spontaneous DNA breaks in the rat brain during development and aging. Mutation Research, 237, 9-15.
34. MULAART, E., BOERRIGTFR, M. E., RAVID, R., SWAAB, D. F. and VIJG, J., 1990b, Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients. Neurobiology of Aging, 11, 109-173.
35. NARASIMHAN, V. and HUH, W. K., 1991. Altered restriction patterns of microwave irradiated lambdaphage DNA. Biochemistry International, 25, 363-370.
36. OSMAK, M., HAN, A., IKEBUCHI, M. and HILL, C. K., 1990, Multiple small exposures of filtered mid-UV radiation increase the resistance of Chinese hamster cells to far-UV, mid-UV and filtered mid-UV radiation. International Journal of Radiation Biology, 97, 345-360.
37. RADFORD, I. R., 1985, The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation. International Journal of Radiation Biology, 48, 45-54.
38. RADFORD, I. R. 1986a, Evidence for a general relationship between the induced level of DNA double-strand breakage and cell killing after X-irradiation of mammalian cells. International Journal of Radiation Biology, 49, 611-620.
39. RADFORD I. R., 1986b, Effect of radiomodifying agents on the ratios of X-ray-induced lesions in cellular DNA: use in lethal lesion determination. International Journal of Radiation Biology, 49, 621-637.
40. ROBBINS, J. H., OTSUKA, F., TARONE, R. E., POLINSKY, R. I., BRUMBACK, R. A., MOSHELL, A. N., NFE, L. E. and GANGES, M. S., 1983, Radiosensitivity in Alzheimer's disease and Parkinson disease. Lancet, i, 468-489.
41. ROJAVIN, M. A. and ZISKIN, M. C., 1995. Effect of millimeter waves on survival of UVC-exposed Escherichia coli. Bioelectromagnetics, 16, 188-196.
42. SAGRIPANTI, J. L. and SWICORD, M. L., 1986, DNA structrual changes caused by microwave radiation. International Journal of Radiation Biology, 50, 47-50.
43. SARKAR, S., ALI, S. and BAHARI, J., 1994, Effects of low power microwave on the mouse genome: a direct DNA analysis. Mutation Research, 320, 141-147.
44. SCUDIERO, D. A., MEYER, S. A., CLATTERBUCK, B. E., TARONE, R. E. and ROBBINS, J. H., 1981, Hypersensitivity to N-methyl-N-nitro-N-nitrosoguanidine in fibroblasts from patients with Huntington disease, familial dysautonomia and other primary neuronal degenerations. Proceedings of the National Academy of Sciences, USA, 78, 6451-6455.
45. SINGH, N. P., GRAHAM, M. M., SINGH, V. and KHAN, A., 1995, Induction of DNA single-strand breaks in human lymphocytes by low-doses of γ-rays. International Journal of Radiation Biology, 68, 563-570.
46. SINGH, N. P., STEPHENS, R. E. and SCHNEIDER, E. L., 1994, Modification of alkaline microgel electrophoresis for sensitive detection of DNA damage. International Journal of Radiation Biology, 66, 23-28.
47. TARGOVNIK, H. S., LOCHER, S. E. and HARIHARAN, P. V., 1985, Age associated alterations in DNA damage and repair capacity in Turbatrix aceti exposed to ionizing radiation. International Journal of Radiation Biology, 47, 255-260.
48. VERSCHAEVE, L., SLAETS, D., VAN GORP, U., MAES, A. and VANKERKOM, J., 1994, In vitro and in vivo genetic effects of microwaves from mobile telephone frequencies in human and rat peripheral blood lymphocytes. Proceedings of Cost 244 Meatings on Mobile Communication and Extremely Low Frequency Field: Instrumentation and Measurements in Bioelectromagnetics Research, Bled, Slovenia, Edited by D. Simunic, pp. 74-83.
49. WARD, J. F., 1990, The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review. International Journal of Radiation Biology, 57, 1141-1150.
50. WHEELER, K. T. and LETT, J. T., 1974, On the possibility that DNA repair is related to age in non-dividing cells. Proceedings of the National Academy of Sciences, USA, 71, 1862-1865.