Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation

Journal of Biological Chemistry

Volumn 285, Issue 6, 2010, Pages 3582-3591

  Ross, Jeremy A ^a   Cheng, Hanyin ^a,b   Nagy, Zsuzsanna S ^a   Frost, Jeffrey A ^c   Kirken, Robert A ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; DNA BINDING ACTIVITY; HUMAN DISEASE; INTERLEUKIN-2; JANUS TYROSINE KINASE; MULTIPLE LEVELS; NATURAL KILLER; PHOSPHATASE ACTIVITY; PROTEIN PHOSPHATASE 2A; PROTEIN PHOSPHATASE-1; PROTEIN PHOSPHORYLATION; RECEPTOR COMPLEX; SERINE PHOSPHORYLATION; SIGNAL TRANSDUCERS; STAUROSPORINES; THERAPEUTIC TARGETS; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; CELL CULTURE; CHEMICAL ACTIVATION; PHOSPHATASES; PROTEINS; SIGNALING;

PHOSPHORYLATION;

CALYCULIN A; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 2 RECEPTOR GAMMA; JANUS KINASE 3; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; SERINE; STAT5 PROTEIN; STAUROSPORINE; THREONINE; TYROSINE; JAK3 PROTEIN, HUMAN; OLIGONUCLEOTIDE; PHOSPHOPROTEIN PHOSPHATASE 2; STAT5A PROTEIN, HUMAN; STAT5B PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID ANALYSIS; ARTICLE; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOPRECIPITATION; LYMPHOCYTE; METABOLISM; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROMOTER REGION; PROTEIN BINDING; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOPRECIPITATION; INTERLEUKIN-2; JANUS KINASE 3; LYMPHOCYTES; OLIGONUCLEOTIDES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; RECEPTORS, INTERLEUKIN-2; SERINE; STAT5 TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEINS; TYROSINE;

EID: 77950469183     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.053843     Document Type: Article

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