The inhibitory effect of hesperidin on tumor cell invasiveness occurs via suppression of activator protein 1 and nuclear factor-kappaB in human hepatocellular carcinoma cells

Toxicology Letters

Volumn 194, Issue 1-2, 2010, Pages 42-49

  Lee, Kuo Hua ^e   Yeh, Ming Hsien ^b   Kao, Shung Te ^c,d   Hung, Che Ming ^e   Liu, Ching Ju ^b   Huang, Yung Yu ^a,b,c,d,e   Yeh, Chia Chou ^a,b  

^a TZU CHI UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e FISHERIES RESEARCH INSTITUTE   (Taiwan)

Author keywords

Activator protein 1; Hesperidin; Matrix metalloproteinase 9; Nuclear factor B; TPA; Tumor invasion

Indexed keywords

GELATINASE B; HESPERIDIN; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CARCINOMA CELL; CELL INVASION; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METASTASIS INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; CANCER INVASION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LIVER TUMOR; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; HESPERIDIN; HUMANS; I-KAPPA B KINASE; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; NF-KAPPA B; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

EID: 77950465549     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.01.021     Document Type: Article

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