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Volumn 30, Issue 3, 1999, Pages 511-518

Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase

Author keywords

Cancer; Hepatocyte growth factor; Invasion; Liver; Urokinase

Indexed keywords

MATRIGEL; SCATTER FACTOR; UROKINASE;

EID: 0032996954     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80113-5     Document Type: Article
Times cited : (61)

References (35)
  • 1
    • 0028176887 scopus 로고
    • α-smooth muscle actin positive perisinusoidal stromal cells in human hepatocellular carcinoma
    • Enzan H, Himeno H, Iwamura S, Onishi S, Saibara T, Yamamoto Y, et al. α-smooth muscle actin positive perisinusoidal stromal cells in human hepatocellular carcinoma. Hepatology. 19:1994;895-903.
    • (1994) Hepatology , vol.19 , pp. 895-903
    • Enzan, H.1    Himeno, H.2    Iwamura, S.3    Onishi, S.4    Saibara, T.5    Yamamoto, Y.6
  • 2
    • 0030683506 scopus 로고    scopus 로고
    • Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: Evidence for a role of hepatocyte growth factor
    • Neaud V, Faouzi S, Guirouilh J, Le Bail B, Balabaud C, Bioulac-Sage P, et al. Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: evidence for a role of hepatocyte growth factor. Hepatology. 26:1997;1458-1486.
    • (1997) Hepatology , vol.26 , pp. 1458-1486
    • Neaud, V.1    Faouzi, S.2    Guirouilh, J.3    Le Bail, B.4    Balabaud, C.5    Bioulac-Sage, P.6
  • 4
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M, Gherardi E, Perryman M, Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature. 327:1987;239-242.
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 5
    • 0025824738 scopus 로고
    • Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
    • Montesano R, Matsumoto K, Nakamura T, Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell. 67:1991;901-908.
    • (1991) Cell , vol.67 , pp. 901-908
    • Montesano, R.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4
  • 6
    • 0025805633 scopus 로고
    • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
    • Bottaro DP, Rubin JS, Faletto DL, Chan AML, Kmiecik TE, Vande Woude GF, et al. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science. 251:1991;802-804.
    • (1991) Science , vol.251 , pp. 802-804
    • Bottaro, D.P.1    Rubin, J.S.2    Faletto, D.L.3    Chan Aml4    Kmiecik, T.E.5    Vande Woude, G.F.6
  • 7
    • 0029149510 scopus 로고
    • Hepatocyte growth factor and its receptor/c-MET regulate both cell growth and invasion of human pancreatic cancer
    • Hasegawa Y, Yamamoto M, Maeda S, Saitoh Y. Hepatocyte growth factor and its receptor/c-MET regulate both cell growth and invasion of human pancreatic cancer. Int J Oncol. 7:1995;877-881.
    • (1995) Int J Oncol , vol.7 , pp. 877-881
    • Hasegawa, Y.1    Yamamoto, M.2    Maeda, S.3    Saitoh, Y.4
  • 8
    • 0029763516 scopus 로고    scopus 로고
    • Acquisition of invasive phenotype in gallbadder cancer cells via mutual interaction of stromal fibroblasts and cancer cells as mediated by hepatocyte growth factor
    • Matsumoto K, Date K, Shimura H, Nakamura T. Acquisition of invasive phenotype in gallbadder cancer cells via mutual interaction of stromal fibroblasts and cancer cells as mediated by hepatocyte growth factor. Jpn J Cancer Res. 87:1996;702-710.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 702-710
    • Matsumoto, K.1    Date, K.2    Shimura, H.3    Nakamura, T.4
  • 9
    • 0030039519 scopus 로고    scopus 로고
    • Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-Met signalling in human cells concomitant with induction of the urokinase proteolysis network
    • Jeffers M, Rong S, Vande Woude GF. Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-Met signalling in human cells concomitant with induction of the urokinase proteolysis network. Mol Cell Biol. 16:1996;1115-1125.
    • (1996) Mol Cell Biol , vol.16 , pp. 1115-1125
    • Jeffers, M.1    Rong, S.2    Vande Woude, G.F.3
  • 10
    • 0026669204 scopus 로고
    • Hepatocyte growth factor increases urokinase-type plasminogen activator (μ-PA) and μ-PA receptor expression in Madin-Darby canine kidney epithelial cells
    • Pepper MS, Matsumoto K, Nakamura T, Orci L, Montesano R. Hepatocyte growth factor increases urokinase-type plasminogen activator (μ-PA) and μ-PA receptor expression in Madin-Darby canine kidney epithelial cells. J Biol Chem. 267:1992;20493-20496.
    • (1992) J Biol Chem , vol.267 , pp. 20493-20496
    • Pepper, M.S.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4    Montesano, R.5
  • 11
    • 0029763184 scopus 로고    scopus 로고
    • Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas
    • Uchiyama A, Essner R, Doi F, Nguyen T, Ramming KP, Nakamura T, et al. Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas. J Cell Biochem. 62:1996;443-453.
    • (1996) J Cell Biochem , vol.62 , pp. 443-453
    • Uchiyama, A.1    Essner, R.2    Doi, F.3    Nguyen, T.4    Ramming Kp5    Nakamura, T.6
  • 12
    • 0022360938 scopus 로고
    • Primary structure of single-chain pro-urokinase
    • Kasai S, Arimura H, Nishida M, Suyama T. Primary structure of single-chain pro-urokinase. J Biol Chem. 260:1985;12382-12389.
    • (1985) J Biol Chem , vol.260 , pp. 12382-12389
    • Kasai, S.1    Arimura, H.2    Nishida, M.3    Suyama, T.4
  • 13
    • 0025052018 scopus 로고
    • Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis
    • Roldan AL, Cubellis MV, Masucci MT, Behrendt N, Lund LR, Dano K, et al. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J. 9:1990;467-474.
    • (1990) EMBO J , vol.9 , pp. 467-474
    • Roldan, A.L.1    Cubellis, M.V.2    Masucci, M.T.3    Behrendt, N.4    Lund, L.R.5    Dano, K.6
  • 14
    • 0031893413 scopus 로고    scopus 로고
    • Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice
    • Carmeliet P, Moons L, Dewerchin M, Rosenberg S, Herbert JM, Lupu F, et al. Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice. J Cell Biol. 140:1998;233-245.
    • (1998) J Cell Biol , vol.140 , pp. 233-245
    • Carmeliet, P.1    Moons, L.2    Dewerchin, M.3    Rosenberg, S.4    Herbert, J.M.5    Lupu, F.6
  • 15
    • 0027314501 scopus 로고
    • Inhibition of urokinase by 4-substituted benzo[b]-thiophene-2-carboxamidines: An important new class of selective synthetic urokinase inhibitors
    • Towle MJ, Lee A, Maduakor EC, Schwartz E, Bridges AJ, Littlefield BA. Inhibition of urokinase by 4-substituted benzo[b]-thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitors. Cancer Res. 53:1993;2553-2559.
    • (1993) Cancer Res , vol.53 , pp. 2553-2559
    • Towle, M.J.1    Lee, A.2    Maduakor, E.C.3    Schwartz, E.4    Bridges, A.J.5    Littlefield, B.A.6
  • 16
    • 0027166733 scopus 로고
    • Mitogenic effect of TGFβ1 on human Ito cell in culture: Evidence for mediation by endogenous platelet derived growth factor
    • Win KM, Charlotte F, Mallat A, Cherqui D, Martin N, Mavier P, et al. Mitogenic effect of TGFβ1 on human Ito cell in culture: evidence for mediation by endogenous platelet derived growth factor. Hepatology. 18:1993;137-145.
    • (1993) Hepatology , vol.18 , pp. 137-145
    • Win, K.M.1    Charlotte, F.2    Mallat, A.3    Cherqui, D.4    Martin, N.5    Mavier, P.6
  • 17
    • 0029119677 scopus 로고
    • Human myofibroblast-like cells obtained by outgrowth are representative of the fibrogenic cells in the liver
    • Blazejewski S, Préaux AM, Mallat A, Brochériou I, Mavier P, Dhumeaux D, et al. Human myofibroblast-like cells obtained by outgrowth are representative of the fibrogenic cells in the liver. Hepatology. 22:1995;788-797.
    • (1995) Hepatology , vol.22 , pp. 788-797
    • Blazejewski, S.1    Préaux, A.M.2    Mallat, A.3    Brochériou, I.4    Mavier, P.5    Dhumeaux, D.6
  • 18
    • 0025853770 scopus 로고
    • Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas
    • Pyke IC, Kristensen P, Ralfkiaer E, Grondahl-Hansen J, Eriksen J, Blasi F, et al. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol. 138:1991;1059-1067.
    • (1991) Am J Pathol , vol.138 , pp. 1059-1067
    • Pyke, I.C.1    Kristensen, P.2    Ralfkiaer, E.3    Grondahl-Hansen, J.4    Eriksen, J.5    Blasi, F.6
  • 19
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem. 102:1980;344-352.
    • (1980) Anal Biochem , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 20
    • 0024544506 scopus 로고
    • Activation of pro-urokinase and plasminogen on human sarcoma cells: A proteolytic system with surface-bound reactants
    • Stephens RW, Pöllänen J, Tapiovaara H, Leung KC, Sim PS, Salonen EM, et al. Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants. J Cell Biol. 108:1989;1987-1995.
    • (1989) J Cell Biol , vol.108 , pp. 1987-1995
    • Stephens, R.W.1    Pöllänen, J.2    Tapiovaara, H.3    Leung, K.C.4    Sim, P.S.5    Salonen, E.M.6
  • 21
    • 0019752371 scopus 로고
    • Assay of coagulation proteases using peptide chromogenic and fiuorogenic substrates
    • Lottenberg R, Christensen U, Jackson MC, Coleman PL. Assay of coagulation proteases using peptide chromogenic and fiuorogenic substrates. Methods Enzymol. 80:1981;341-381.
    • (1981) Methods Enzymol , vol.80 , pp. 341-381
    • Lottenberg, R.1    Christensen, U.2    Jackson, M.C.3    Coleman, P.L.4
  • 22
    • 0027314980 scopus 로고
    • An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator
    • Pyke C, Eriksen J, Solberg H, Schnack Nielsen B, Kristensen P, Lund LR, et al. An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator. FEBS Lett. 326:1993;69-73.
    • (1993) FEBS Lett , vol.326 , pp. 69-73
    • Pyke, C.1    Eriksen, J.2    Solberg, H.3    Schnack Nielsen, B.4    Kristensen, P.5    Lund, L.R.6
  • 23
    • 0028337426 scopus 로고
    • Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in HepG2 cells
    • Wojta J, Nakamura T, Fabry A, Hufnagl P, Beckmann R, McGrath K, et al. Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in HepG2 cells. Blood. 8:1994;151-157.
    • (1994) Blood , vol.8 , pp. 151-157
    • Wojta, J.1    Nakamura, T.2    Fabry, A.3    Hufnagl, P.4    Beckmann, R.5    McGrath, K.6
  • 24
    • 0025867052 scopus 로고
    • Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells
    • Cohen RL, Xi XP, Crowley CW, Lucas BK, Levinson AD, Shuman MA. Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells. Blood. 78:1991;479-487.
    • (1991) Blood , vol.78 , pp. 479-487
    • Cohen, R.L.1    Xi, X.P.2    Crowley, C.W.3    Lucas, B.K.4    Levinson, A.D.5    Shuman Ma6
  • 25
    • 0025908960 scopus 로고
    • Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancer
    • Hollas W, Blasi F, Boyd D. Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancer. Cancer Res. 51:1991;3690-3695.
    • (1991) Cancer Res , vol.51 , pp. 3690-3695
    • Hollas, W.1    Blasi, F.2    Boyd, D.3
  • 26
    • 0031594327 scopus 로고    scopus 로고
    • Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines
    • Kamiyama T, Une Y, Uchino J, Hamada J. Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines. Int J Oncol. 12:1998;655-659.
    • (1998) Int J Oncol , vol.12 , pp. 655-659
    • Kamiyama, T.1    Une, Y.2    Uchino, J.3    Hamada, J.4
  • 27
    • 0030907299 scopus 로고    scopus 로고
    • Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation
    • Baramova EN, Bajou K, Remacle A, L'Hoir C, Krell HW, Weidle UH, et al. Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation. FEBS Lett. 405:1997;157-162.
    • (1997) FEBS Lett , vol.405 , pp. 157-162
    • Baramova, E.N.1    Bajou, K.2    Remacle, A.3    L'Hoir, C.4    Krell, H.W.5    Weidle, U.H.6
  • 28
    • 0027077443 scopus 로고
    • Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor
    • Naldini L, Tamagnone L, Vigna E, Sachs M, Hartmann G, Birchmeier W, et al. Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J. 11:1992;4825-4833.
    • (1992) EMBO J , vol.11 , pp. 4825-4833
    • Naldini, L.1    Tamagnone, L.2    Vigna, E.3    Sachs, M.4    Hartmann, G.5    Birchmeier, W.6
  • 29
    • 0027289115 scopus 로고
    • Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor
    • Miyazawa K, Shimomura T, Kitamura A, Kondo J, Morimoto Y, Kitamura N. Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. J Biol Chem. 268:1993;10024-10028.
    • (1993) J Biol Chem , vol.268 , pp. 10024-10028
    • Miyazawa, K.1    Shimomura, T.2    Kitamura, A.3    Kondo, J.4    Morimoto, Y.5    Kitamura, N.6
  • 30
    • 0026754414 scopus 로고
    • Proteolytic processing of the 72 000-Da type IV collagenase by urokinase plasminogen activator
    • Keski-Oja J, Lohi J, Tuuttila A, Tryggvason K, Vartio T. Proteolytic processing of the 72 000-Da type IV collagenase by urokinase plasminogen activator. Exp Cell Res. 202:1992;471-476.
    • (1992) Exp Cell Res , vol.202 , pp. 471-476
    • Keski-Oja, J.1    Lohi, J.2    Tuuttila, A.3    Tryggvason, K.4    Vartio, T.5
  • 31
    • 0028023631 scopus 로고
    • Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells
    • Abe T, Mori T, Kohno K, Seiki M, Hayakawa T, Welgus HG, et al. Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells. Clin Exp Metast. 12:1994;296-304.
    • (1994) Clin Exp Metast , vol.12 , pp. 296-304
    • Abe, T.1    Mori, T.2    Kohno, K.3    Seiki, M.4    Hayakawa, T.5    Welgus, H.G.6
  • 32
    • 0343051765 scopus 로고    scopus 로고
    • In situ detection of matrix metalloproteinase-2 (MMP-2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis
    • Musso O, Théret N, Campion JP, Turlin B, Milani S, Grappone C, et al. In situ detection of matrix metalloproteinase-2 (MMP-2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis. J Hepatol. 26:1997;593-605.
    • (1997) J Hepatol , vol.26 , pp. 593-605
    • Musso, O.1    Théret, N.2    Campion, J.P.3    Turlin, B.4    Milani, S.5    Grappone, C.6
  • 33
    • 0030915291 scopus 로고    scopus 로고
    • Expression of urokinase-type plasminogen activator receptor in hepatocellular carcinoma
    • Morita Y, Hayashi Y, Wang Y, Kanamaru T, Suzuki S, Kawasaki K, et al. Expression of urokinase-type plasminogen activator receptor in hepatocellular carcinoma. Hepatology. 25:1997;856-861.
    • (1997) Hepatology , vol.25 , pp. 856-861
    • Morita, Y.1    Hayashi, Y.2    Wang, Y.3    Kanamaru, T.4    Suzuki, S.5    Kawasaki, K.6
  • 34
    • 0030795071 scopus 로고    scopus 로고
    • Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428
    • Xing RH, Mazar A, Henkin J, Rabbani A. Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428. Cancer Res. 57:1997;3585-3593.
    • (1997) Cancer Res , vol.57 , pp. 3585-3593
    • Xing, R.H.1    Mazar, A.2    Henkin, J.3    Rabbani, A.4
  • 35
    • 0029789744 scopus 로고    scopus 로고
    • Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model
    • Alonso DF, Farias EF, Ladeda V, Davel L, Puricelli L, Bal De Kier Joffé E. Effects of synthetic urokinase inhibitors on local invasion and metastasis in a murine mammary tumor model. Cancer Res. 40:1996;209-223.
    • (1996) Cancer Res , vol.40 , pp. 209-223
    • Alonso, D.F.1    Farias, E.F.2    Ladeda, V.3    Davel, L.4    Puricelli, L.5    Bal De Kier Joffé, E.6


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