An absolute role of the PKC-dependent NF-κB activation for induction of MMP-9 in hepatocellular carcinoma cells

Biochemical and Biophysical Research Communications

Volumn 305, Issue 2, 2003, Pages 428-433

  Hah, Nasun ^a   Lee, Seung Taek ^a  

^a Yonsei University   (South Korea)

Author keywords

Extracellular signal regulated kinase; Hepatocellular carcinoma; MMP 9; NF B; Phorbol 12 myristate 13 acetate; Protein kinase C

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SALAZOSULFAPYRIDINE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CANCER INVASION; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME RELEASE; GENE MUTATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 0038705309     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00788-5     Document Type: Article

References (26)

1. Woessner J.F. Jr. MMPs and TIMPs-an historical perspective. Mol. Biotechnol. 22:2002;33-49.
2. Sato H., Seiki M. Regulatory mechanism of 92-kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene. 81993:1993;395-405.
3. Liu P., Kimmoun E., Legrand A., Sauvanet A., Degott C., Lardeux B., Bernuau D. Activation of NF-κB, AP-1, and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas. J. Hepatol. 37:2002;63-71.
4. Zeigler M.E., Chi Y., Schmidt T., Varani J. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes. J. Cell Physiol. 180:1999;271-284.
5. Hozumi A., Nishimura Y., Nishiuma T., Kotani Y., Yokoyama M. Induction of MMP-9 in normal human bronchial epithelial cells by TNF-α via NF-κB-mediated pathway. Am. J. Physiol. Lung. Cell. Mol. Physiol. 281:2001;L1444-L1452.
6. Gum R., Wang H., Lengyel E., Juarez J., Boyd D. Regulation of 92-kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades. Oncogene. 14:1997;1481-1493.
7. Newton A.C. Regulation of protein kinase C. Curr. Opin. Cell. Biol. 9:1997;161-167.
8. Juarez J., Clayman G., Nakajima M., Tanabe K.K., Saya H., Nicolson G.L., Boyd D. Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity. Int. J. Cancer. 55:1993;10-18.
9. Genersch E., Hayess K., Neuenfeld Y., Haller H. Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways. J. Cell Sci. 113:2000;4319-4330.
10. Shin M., Yan C., Boyd D. An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding, and PMA-inducible 92-kDa type IV collagenase expression. Biochim. Biophys. Acta. 1589:2002;311-316.
11. Simon C., Goepfert H., Boyd D. Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92, 000 type IV collagenase secretion and in vitro invasion. Cancer Res. 58:1998;1135-1139.
12. Bond M., Fabunmi R.P., Baker A.H., Newby A.C. Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-κB. FEBS Lett. 435:1998;29-34.
13. Esteve P.O., Chicoine E., Robledo O., Aoudjit F., Descoteaux A., Potworowski E.F., St-Pierre Y. Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-α in glioma cells via NF-κB. J. Biol. Chem. 277:2002;35150-35155.
14. Liu F., Qi H.L., Chen H.L. Regulation of differentiation- and proliferation-inducers on Lewis antigens, α-fucosyltransferase, and metastatic potential in hepatocarcinoma cells. Br. J. Cancer. 84:2001;1556-1563.
15. Masure S., Billiau A., Van Damme J., Opdenakker G. Human hepatoma cells produce an 85-kDa gelatinase regulated by phorbol-12-myristate-13-acetate. Biochim. Biophys. Acta. 1054:1990;317-325.
16. Kim Y.-M., Jang J.-W., Lee O.-H., Yeon J., Choi E.-Y., Kim K.-W., Lee S.-T., Kwon Y.-G. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res. 60:2000;5410-5413.
17. Jo Y., Yoon D.-W., Kim M.-Y., Lee Y.-J., Kim H.-J., Lee S.-T. Tissue inhibitor of metalloproteinases-2 inhibits the 4-aminophenylmercuric acetate-induced activation and autodegradation of the free promatrix metalloproteinase-2. J. Biochem. Mol. Biol. 32:1999;60-66.
18. Jo Y., Yeon J., Kim H.-J., Lee S.-T. Analysis of tissue inhibitor of metalloproteinases-2 effect on pro-matrix metalloproteinase-2 activation by membrane-type 1 matrix metalloproteinase using baculovirus/insect-cell expression system. Biochem. J. 345:2000;511-519.
19. Levy A.T., Cioce V., Sobel M.E., Garbisa S., Grigioni W.F., Liotta L.A., Stetler-Stevenson W.G. Increased expression of the Mr 72, 000 type IV collagenase in human colonic adenocarcinoma. Cancer Res. 51:1991;439-444.
20. Buisson-Legendre N., Bernard P., Bobichon H., Emonard H., Schneider C., Maquart F.X., Haye B., Hornebeck W. Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth. Biochem. Biophys. Res. Commun. 260:1999;634-640.
21. Williger B.T., Ho W.T., Exton J.H. Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells. J. Biol. Chem. 274:1999;735-738.
22. Chen F., Castranova V., Shi X., Demers L.M. New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases. Clin. Chem. 45:1999;7-17.
23. Beg A.A., Sha W.C., Bronson R.T., Ghosh S., Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature. 376:1995;167-170.
24. Cressman D.E., Greenbaum L.E., Haber B.A., Taub R. Rapid activation of post-hepatectomy factor/nuclear factor-κB in hepatocytes, a primary response in the regenerating liver. J. Biol. Chem. 269:1994;30429-30435.
25. Hellerbrand C., Jobin C., Iimuro Y., Licato L., Sartor R.B., Brenner D.A. Inhibition of NFκB in activated rat hepatic stellate cells by proteasome inhibitors and an IκB super-repressor. Hepatology. 27:1998;1285-1295.
26. Arsura M., Mercurio F., Oliver A.L., Thorgeirsson S.S., Sonenshein G.E. Role of the IκB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells. Mol. Cell. Biol. 20:2000;5381-5391.