Long-term effects of weight loss with a very low carbohydrate and low fat diet on vascular function in overweight and obese patients: Original Article

Journal of Internal Medicine

Volumn 267, Issue 5, 2010, Pages 452-461

  Wycherley, T P ^a,b   Brinkworth, G D ^a   Keogh, J B ^a   Noakes, M ^a   Buckley, J D ^c   Clifton, P M ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Cardiovascular disease; Endothelial function; Flow mediated dilatation

Indexed keywords

ADIPONECTIN; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; CHOLESTEROL; CYANOCOBALAMIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FOLIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMINOGEN ACTIVATOR INHIBITOR 1; SATURATED FATTY ACID; TISSUE PLASMINOGEN ACTIVATOR; TRIACYLGLYCEROL; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ARTERY BLOOD FLOW; ARTICLE; AUGMENTATION INDEX; BLOOD VESSEL FUNCTION; BODY MASS; BODY WEIGHT; CALORIC RESTRICTION; CARBOHYDRATE DIET; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DYSLIPIDEMIA; FEMALE; FOOD COMPOSITION; HUMAN; HYPERTENSION; INTERMETHOD COMPARISON; LIPID DIET; LOW CARBOHYDRATE DIET; LOW FAT DIET; MALE; OBESITY; PRIORITY JOURNAL; PULSE WAVE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM; VASODILATATION; VEIN BLOOD FLOW; WEIGHT REDUCTION;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRACHIAL ARTERY; DIET, CARBOHYDRATE-RESTRICTED; DIET, FAT-RESTRICTED; ENDOTHELIUM, VASCULAR; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; LIPIDS; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; VITAMIN B 12; WEIGHT LOSS;

EID: 77950464529     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2009.02174.x     Document Type: Article

References (50)

1. Lichtenstein AH, Appel LJ, Brands M et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation 2006 114 : 82 96., ACTR No:12606000203550. (Pubitemid 44305278)
2. Hession M, Rolland C, Kulkarni U, Wise A, Broom J. Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities. Obes Rev 2009 10 : 36 50.
3. Kromhout D, Menotti A, Bloemberg B et al. Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. Prev Med 1995 24 : 308 315.
4. Foster GD, Wyatt HR, Hill JO et al. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med 2003 348 : 2082 2090. (Pubitemid 36583303)
5. Samaha FF, Iqbal N, Seshadri P et al. A low-carbohydrate as compared with a low-fat diet in severe obesity. N Engl J Med 2003 348 : 2074 2081. (Pubitemid 36583302)
6. Gardner CD, Kiazand A, Alhassan S et al. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA 2007 297 : 969 977. (Pubitemid 46376751)
7. Brinkworth GD, Noakes M, Buckley JD, Keogh JB, Clifton PM. Long-term effects of a very-low-carbohydrate weight loss diet compared with an isocaloric low-fat diet after 12 mo. Am J Clin Nutr 2009 90 : 23 32.
8. Shai I, Schwarzfuchs D, Henkin Y et al. Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med 2008 359 : 229 241. (Pubitemid 352008438)
9. Nordmann AJ, Nordmann A, Briel M et al. Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials. Arch Intern Med 2006 166 : 285 293. (Pubitemid 43244316)
10. Braunwald E. Shattuck lecture - cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities. N Engl J Med 1997 337 : 1360 1369. (Pubitemid 27467771)
11. Hope SA, Meredith IT. Cellular adhesion molecules and cardiovascular disease. Part I. Their expression and role in atherogenesis. Int Med J 2003 33 : 380 386.
12. Thogersen AM, Jansson JH, Boman K et al. High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infarction in both men and women: evidence for the fibrinolytic system as an independent primary risk factor. Circulation 1998 98 : 2241 2247. (Pubitemid 28533841)
13. Smith FB, Lee AJ, Rumley A, Fowkes FG, Lowe GD. Tissue-plasminogen activator, plasminogen activator inhibitor and risk of peripheral arterial disease. Atherosclerosis 1995 115 : 35 43.
14. Arita Y, Kihara S, Ouchi N et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999 257 : 79 83. (Pubitemid 29299050)
15. Keogh JB, Brinkworth GD, Clifton PM. Effects of weight loss on a low-carbohydrate diet on flow-mediated dilatation, adhesion molecules and adiponectin. Br J Nutr 2007 98 : 852 859.
16. Sharman MJ, Volek JS. Weight loss leads to reductions in inflammatory biomarkers after a very-low-carbohydrate diet and a low-fat diet in overweight men. Clin Sci (Lond) 2004 107 : 365 369.
17. Murakami T, Horigome H, Tanaka K et al. Impact of weight reduction on production of platelet-derived microparticles and fibrinolytic parameters in obesity. Thromb Res 2007 119 : 45 53. (Pubitemid 44716205)
18. Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 2005 26 : 439 451. (Pubitemid 40686653)
19. Keogh JB, Brinkworth GD, Noakes M, Belobrajdic DP, Buckley JD, Clifton PM. Effects of weight loss from a very-low-carbohydrate diet on endothelial function and markers of cardiovascular disease risk in subjects with abdominal obesity. Am J Clin Nutr 2008 87 : 567 576. (Pubitemid 351364536)
20. Hashimoto M, Akishita M, Eto M et al. The impairment of flow-mediated vasodilatation in obese men with visceral fat accumulation. Int J Obes Relat Metab Disord 1998 22 : 477 484. (Pubitemid 28211977)
21. Rossi R, Nuzzo A, Origliani G, Modena MG. Prognostic role of flow-mediated dilation and cardiac risk factors in post-menopausal women. J Am Coll Cardiol 2008 51 : 997 1002. (Pubitemid 351318128)
22. Vogel RA, Corretti MC, Plotnick GD. Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardiol 1997 79 : 350 354.
23. Tentolouris N, Arapostathi C, Perrea D, Kyriaki D, Revenas C, Katsilambros N. Differential effects of two isoenergetic meals rich in saturated or monounsaturated fat on endothelial function in subjects with type 2 diabetes. Diabetes Care 2008 31 : 2276 2278.
24. Keogh JB, Grieger JA, Noakes M, Clifton PM. Flow-mediated dilatation is impaired by a high-saturated fat diet but not by a high-carbohydrate diet. Arterioscler Thromb Vasc Biol 2005 25 : 1274 1279. (Pubitemid 40776621)
25. Miller M, Beach V, Sorkin JD et al. Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance. J Am Diet Assoc 2009 109 : 713 717.
26. Fuentes F, Lopez-Miranda J, Sanchez E et al. Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men. Ann Intern Med 2001 134 : 1115 1119.
27. Rallidis LS, Lekakis J, Kolomvotsou A et al. Close adherence to a Mediterranean diet improves endothelial function in subjects with abdominal obesity. Am J Clin Nutr 2009 90 : 263 268.
28. Phillips SA, Jurva JW, Syed AQ et al. Benefit of low-fat over low-carbohydrate diet on endothelial health in obesity. Hypertension 2008 51 : 376 382.
29. Buscemi S, Verga S, Tranchina MR, Cottone S, Cerasola G. Effects of hypocaloric very-low-carbohydrate diet vs. Mediterranean diet on endothelial function in obese women*. Eur J Clin Invest 2009 39 : 339 347.
30. Alberti KG, Zimmet P, Shaw J. Metabolic syndrome - a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med 2006 23 : 469 480.
31. Corretti MC, Anderson TJ, Benjamin EJ et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 2002 39 : 257 265.
32. Jarvisalo MJ, Jartti L, Karvonen MK et al. Enhanced endothelium-dependent vasodilation in subjects with Proline7 substitution in the signal peptide of neuropeptide Y. Atherosclerosis 2003 167 : 319 326. (Pubitemid 36773531)
33. Eskurza I, Monahan KD, Robinson JA, Seals DR. Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol 2004 556 : 315 324. (Pubitemid 38519054)
34. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972 18 : 499 502.
35. Raitakari OT, Celermajer DS. Flow-mediated dilatation. Br J Clin Pharmacol 2000 50 : 397 404.
36. Joannides R, Haefeli WE, Linder L et al. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 1995 91 : 1314 1319.
37. Kuvin JT, Patel AR, Sliney KA, Pandian NG, Karas RH. Comparison of flow-mediated dilatation of the brachial artery in coronary patients with low-density lipoprotein cholesterol levels 80 mg/dl versus patients with levels <80 to 100 mg/dl. Am J Cardiol 2005 95 : 93 5.
38. Woo KS, Chook P, Chan LL et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. Am J Med 2002 112 : 535 539. (Pubitemid 34518312)
39. Woo KS, Chook P, Lolin YI, Sanderson JE, Metreweli C, Celermajer DS. Folic acid improves arterial endothelial function in adults with hyperhomocystinemia. J Am Coll Cardiol 1999 34 : 2002 2006. (Pubitemid 30002657)
40. Esposito K, Marfella R, Ciotola M et al. Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA 2004 292 : 1440 1446. (Pubitemid 39258336)
41. Clifton PM, Keogh JB, Foster PR, Noakes M. Effect of weight loss on inflammatory and endothelial markers and FMD using two low-fat diets. Int J Obes (Lond) 2005 29 : 1445 1451. (Pubitemid 41622223)
42. Toto-Moukouo JJ, Achimastos A, Asmar RG, Hugues CJ, Safar ME. Pulse wave velocity in patients with obesity and hypertension. Am Heart J 1986 112 : 136 140. (Pubitemid 16066267)
43. Boutouyrie P, Tropeano AI, Asmar R et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension 2002 39 : 10 5. (Pubitemid 34098081)
44. Ouchi N, Kihara S, Arita Y et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999 100 : 2473 2476. (Pubitemid 30005109)
45. Kobayashi K, Akishita M, Yu W, Hashimoto M, Ohni M, Toba K. Interrelationship between non-invasive measurements of atherosclerosis: flow-mediated dilation of brachial artery, carotid intima-media thickness and pulse wave velocity. Atherosclerosis 2004 173 : 13 8. (Pubitemid 38224191)
46. Cushman M, Lemaitre RN, Kuller LH et al. Fibrinolytic activation markers predict myocardial infarction in the elderly. The Cardiovascular Health Study. Arterioscler Thromb Vasc Biol 1999 19 : 493 498. (Pubitemid 29135146)
47. Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 2004 291 : 1730 1737. (Pubitemid 38489895)
48. Selhub J. The many facets of hyperhomocysteinemia: studies from the Framingham cohorts. J Nutr 2006 136 : 1726S 30S.
49. Malinow MR, Bostom AG, Krauss RM. Homocyst(e)ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation 1999 99 : 178 182. (Pubitemid 29035977)
50. Allen LH. Causes of vitamin B12 and folate deficiency. Food Nutr Bull 2008 29 : S20 34.