Characterization of the colchicine binding site on avian tubulin isotype βVI

Biochemistry

Volumn 49, Issue 13, 2010, Pages 2932-2942

  Sharma, Shubhada ^a   Poliks, Barbara ^a   Chiauzzi, Colby ^a   Ravindra, Rudravajhala ^a   Blanden, Adam R ^a   Bane, Susan ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; ANTI-MICROTUBULE DRUGS; BINDING DOMAIN; BINDING MODES; BOVINE BRAIN; COLCHICINE BINDING; DRUG BINDING; EUKARYOTIC CELLS; EXPERIMENTAL CONDITIONS; HEMATOPOIETIC CELL; KINETIC EXPERIMENT; MICROTUBULES; MULTIPLE GENES; NOCODAZOLE; PACLITAXEL; PODOPHYLLOTOXIN; RING SIZES; RING STRUCTURES; RING SUBSTITUENTS; UNIVERSAL PROPERTIES;

AMINO ACIDS; BINDING ENERGY; ISOMERS; ORGANIC ACIDS;

LIGANDS;

ALLOCOLCHICINE; AMINO ACID; BETA TUBULIN; BETA TUBULIN 1; BETA TUBULIN 2; BETA TUBULIN 3; BETA TUBULIN 4; CHLOROCOLCHICINE; COLCHICINE; NOCODAZOLE; PACLITAXEL; PODOPHYLLOTOXIN; THIOCOLCHICINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; ERYTHROCYTE; HEMATOPOIETIC CELL; MICROTUBULE ASSEMBLY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RING FINGER MOTIF; SEQUENCE ALIGNMENT;

AMINO ACIDS; ANIMALS; BINDING SITES; CHICKENS; COLCHICINE; ERYTHROCYTES; LIGANDS; PROTEIN BINDING; PROTEIN ISOFORMS; TUBULIN;

AVES; BOVINAE; EUKARYOTA; GALLUS GALLUS;

EID: 77950435847     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100159p     Document Type: Article

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