Role of the colchicine ring A and its methoxy groups in the binding to tubulin and microtubule inhibition

Biochemistry

Volumn 37, Issue 23, 1998, Pages 8356-8368

  Andreu, Jose M ^b   Perez Ramirez, Bernardo ^a,c   Gorbunoff, Marina J ^a   Ayala, David ^b   Timasheff, Serge N ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; TUBULIN;

ARTICLE; DRUG BINDING; ENZYME ACTIVITY; LIGAND BINDING; MICROTUBULE ASSEMBLY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

ANIMALS; BINDING SITES; CATTLE; COLCHICINE; ENZYME INDUCTION; GTP PHOSPHOHYDROLASES; LIGANDS; MICROTUBULES; TUBULIN; TUBULIN MODULATORS;

EID: 0032499648     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9728553     Document Type: Article

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