Efficient downregulation of multiple mRNA targets with a single shRNA-expressing lentiviral vector

Plasmid

Volumn 63, Issue 3, 2010, Pages 143-149

  Chumakov, Stepan P ^a,c   Kravchenko, Julia E ^a,c   Prassolov, Vladimir S ^a   Frolova, Elena I ^b   Chumakov, Peter M ^a,c  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Lentiviral vectors; Multiplex shRNA expression; RNAi mediated gene silencing

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; LENTIVIRUS VECTOR; MESSENGER RNA; PEROXIREDOXIN 3; SESTRIN 1; SESTRIN 2; SESTRIN 3; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CELL SELECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG SYNTHESIS; EXPRESSION VECTOR; GENE LOCATION; GENE REPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; LONG TERMINAL REPEAT; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROMOTER REGION; RNA SYNTHESIS;

CELL LINE; DOWN-REGULATION; GENETIC VECTORS; HUMANS; LENTIVIRUS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RNA POLYMERASE III; RNA, MESSENGER; RNA, SMALL INTERFERING; TERMINAL REPEAT SEQUENCES;

EID: 77950369833     PISSN: 0147619X     EISSN: 10959890     Source Type: Journal    
DOI: 10.1016/j.plasmid.2009.12.003     Document Type: Article

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