Essential fatty acids for dry eye: A review

Contact Lens and Anterior Eye

Volumn 33, Issue 2, 2010, Pages 49-54

  Roncone, Marco ^a   Bartlett, Hannah ^a   Eperjesi, Frank ^a  

^a ASTON UNIVERSITY   (United Kingdom)

Author keywords

Alpha linoleic acid; Dry eye syndrome; Essential fatty acids; Linoleic acid; Omega 3

Indexed keywords

DOCOSAHEXAENOIC ACID; ESSENTIAL FATTY ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; OMEGA 3 FATTY ACID; PROSTAGLANDIN;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTHRITIS; CLINICAL FEATURE; CORNEA; DIET SUPPLEMENTATION; DRUG DOSAGE FORM COMPARISON; DRY EYE; EPITHELIUM CELL; HUMAN; ISCHEMIC HEART DISEASE; LACRIMAL GLAND; LIPID BILAYER; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SYMPTOM; TEAR FILM;

DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRY EYE SYNDROMES; FATTY ACIDS, ESSENTIAL; HUMANS; PREVALENCE; TREATMENT OUTCOME;

EID: 77950368768     PISSN: 13670484     EISSN: 14765411     Source Type: Journal    
DOI: 10.1016/j.clae.2009.11.002     Document Type: Review

References (49)

1. Bron A. Diagnosis of dry eye. Surv Ophthalmol 2001, 45:S221-S226.
2. Calonge M. The treatment of dry eye. Surv Ophthalmol 2001, 45:S227-S239.
3. Albietz J. Prevalence of dry eye subtypes in clinical optometric practice. Optom Vis Sci 2000, 77:357-363.
4. Moss S., Klein R., Klein B. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol 2000, 118:1264-1268.
5. Doughty M., Fonn D., Richter D., Simpson T., Caffrey B., Gordon K., et al. A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada. Optom Vis Sci 1997, 74:624-631.
6. Nichols K., Begley C., Caffrey B., Jones L. Symptoms of ocular irritation in patients diagnosed with dry eye. Optom Vis Sci 1999, 76:838-844.
7. Begley C., Chalmers R., Mitchell G., Nichols K., Caffrey B., Simpson T., et al. Characterization of ocular surface symptoms from optometric practices in North America. Cornea 2001, 20:610-618.
8. Orsborn G., Zantos S. Practitioner survey: management of dry eye symptoms in soft contact lens wearers. Contact Lens Spectrum 1989, 4:23-26.
9. McCarty C., Bansal A., Livingstone P., Stanislavsky Y., Taylor H. The epidemiology of dry eye in Melbourne, Australia. Ophthalmology 1998, 105:1114-1118.
10. Lemp M. Report of the National Eye Institute/Industry Workshop on Clinical trials in Dry Eye. CLAO J 1995, 21:221-232.
11. Foulks G., Lemp M., Jester J., Sutphin J., Murube J., Novack G. Report of the International Dry Eye Workshop (DEWS). Ocul Surf 2007, 5:65-203.
12. Gilbard J. Dry eye and the role of nutrition. Optom Today 2004, (June):34-41.
13. Gilbard J., Rossi S., Gray K. A new rabbit model for keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci 1987, 28:225-228.
14. Huang F., Tseng S., Shih M., Chen F. Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes. Ophthalmology 2002, 109:1934-1940.
15. Ketelson H., Asgharian B., Chowhan M., Meadows D. Characterization of physical property attributes for polymer systems used in artificial tear products. Invest Ophthalmol Vis Sci 2004, 45. E-Abstract 70.
16. Korb D., Scaffidi R., Greiner J., Kenyon K., Herman J., Blackie C., et al. The effect of two novel lubricant eye drops on tear film lipid layer thickness in subjects with dry eye symptoms. Optom Vis Sci 2005, 82:594-601.
17. Ridder W., Tomlinson A., Paugh J. Effect of artificial tears on visual performance in subjects with dry eye. Optom Vis Sci 2005, 82:835-842.
18. Caffrey B. Influence of diet on tear function. Optom Vis Sci 1991, 68:58-72.
19. Srinivasan S. Is there a role for nutritional supplements in dry eye?. Ann Acad Med 2007, 36:S45-S49.
20. Simopoulos A. Omega-3 fatty acids in inflammation and autoimmune disease. J Am Coll Nutr 2002, 21:495-505.
21. Hibbeln J., Nieminen L., Blasbalg T., Riggs J., Lands W. Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity. Am J Clin Nutr 2006, 83.
22. Simopoulos A. Evolutionary aspects of diet, essential fatty acids and cardiovascular disease. Eur Heart J 2001, 2001:D8-D21.
23. Schein O., Hochberg M., Munoz B., Tielsch J., Bandeen-Roche K., Provost T., et al. Dry eye and dry mouth in the elderly: a population-based assessment. Arch Int Med 1999, 159:1359-1363.
24. Chia E., Mitchell P., Rochtchina E., Le A., Maroun R., Wang J. Prevalence and associations of dry eye syndrome in an older population: the Blue Mountains Eye Study. Clin Exp Ophthalmol 2003, 31:229-232.
25. Schein O., Munoz B., Tielsch J.M., Bandeen-Roche K., West S. Prevalence of dry eye among the elderly. Am J Ophthalmol 1997, 124:723-728.
26. Miljanovic B., Sullivan D., Schaumberg D. Impact of dry eye syndrome on vision-related quality of life. Am J Ophthalmol 2007, 143:409-415.
27. Goldberg R., Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain 2007, 129:210-223.
28. Badouin C. The pathology of dry eye. Surv Ophthalmol 2001, 45:S211-S220.
29. Delaleu N., Immervoll H., Cornelius J., Jonsson R. Biomarker profiles in serum and saliva of experimental Sjogren's Syndrome: associations with specific autoimmune manifestations. Arthritis Res Ther 2008, 10:R22.
30. Brewitt H. Dry eye disease: the scale of the problem. Surv Ophthalmol 2001, 45:S199-S202.
31. Pinna A., Piccinini P., Carta F. Effect of oral linolein and gamma-linoleic acid on meibomian gland dysfunction. Cornea 2007, 26:260-264.
32. Meijer J., Pijpe J., Bootsma H., Vissink A., Kallenberg C. The future of biologic agents in the treatment of Sjogren's syndrome. Clin Rev Allergy Immunol 2007, 32:292-297.
33. 1 tear content in Sjogren's patients. Invest Ophthalmol Vis Sci 2005, 46:4474-4479.
34. Barabino S., Rolando M., Camicione P., Ravera G., Zanardi S., Guiffrida S., et al. Systemic linoleic and gamma-linoleic acid therapy in dry eye syndrome with an inflammatory component. Cornea 2003, 22:97-101.
35. Kokke K., Morris J., Lawrenson J. Oral omega-6 essential fatty acid treatment in contact lens associated dry eye. CLAE 2008, 31:141-146.
36. Milijanovic B., Trivedi K., Dana M., Gilbard J., Buring J., Schaumberg D. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr 2005, 82:887-893.
37. Food Standards Agency (Accessed 2009) Eat Well, Be Well: Fish and shellfish: http://www.eatwell.gov.uk/healthydiet/nutritionessentials/fishandshellfish/oilyfishshellfishandomega3/.
38. Rashid S., Jin Y., Ecoiffier T., Barabino S., Schaumberg D., Dana M. Topical omega-3 and omeg-6 fatty acids for treatment of dry eye. Arch Ophthalmol 2008, 126:219-225.
39. Ophthalmology Times. Nutritional supplementation stimulates tear production, 15th May 2003, 28.
40. Sullivan B., Cermak J., Sullivan R., Papas A., Evans J., Dana M., et al. Correlation between nutrient intake and the polar lipid profiles of meibomian gland secretions in women with Sjogren's syndrome. Adv Exp Med Biol 2002, 506:441-447.
41. Pflugfelder S., Jones D., Ji Z., Afonso A., Monroy D. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjogren's syndrome keratoconjunctivitis sicca. Curr Eye Res 1999, 19:201-211.
42. McGahon B., Martin D., Horrobin D., Lynch M. Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids. Neuroscience 1999, 94:305-314.
43. Calder P., Zurier R. Polyunsaturated fatty acids and rheumatoid arthritis. Curr Opin Clin Nutr Metab Care 2001, 4:115-121.
44. Lands W. Diets could prevent many diseases. Lipids 2003, 38:317-321.
45. Kris-Etherton P., Taylor D., Yu-Poth S., Huth P., Moriarty K., Fishell V., et al. Polyunsaturated fatty acids in the food chain in the United States. Am J Clin Nutr 2007, 71:S179-S188.
46. Lands W. Dietary fat and health: the evidence and the politics of prevention-careful use of dietary fats can improve life and prevent disease. Ann NY Acad Sci 2005, 1055:179-192.
47. Sugano M., Hirahara F. Polyunsaturated fatty acids in the food chain in Japan. Am J Clin Nutr 2000, 71:S189-S196.
48. Zoukhri D. Effect of inflammation on lacrimal gland function. Exp Eye Res 2006, 82:885-898.
49. Harris W. You are what you eat applies to fish too. J Am Diet Assoc 2008, 108:1131-1133.